Incidental Mutation 'R4261:Zcwpw2'
ID322661
Institutional Source Beutler Lab
Gene Symbol Zcwpw2
Ensembl Gene ENSMUSG00000032443
Gene Namezinc finger, CW type with PWWP domain 2
Synonyms4930430K04Rik
MMRRC Submission 041074-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.074) question?
Stock #R4261 (G1)
Quality Score225
Status Validated
Chromosome9
Chromosomal Location117876000-118040259 bp(-) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) T to C at 117998914 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000104810
Predicted Effect noncoding transcript
Transcript: ENSMUST00000111769
SMART Domains Protein: ENSMUSP00000107399
Gene: ENSMUSG00000032443

DomainStartEndE-ValueType
Pfam:zf-CW 14 62 1.5e-18 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000187803
Predicted Effect noncoding transcript
Transcript: ENSMUST00000191100
Predicted Effect noncoding transcript
Transcript: ENSMUST00000217232
Coding Region Coverage
  • 1x: 99.3%
  • 3x: 98.7%
  • 10x: 97.4%
  • 20x: 95.6%
Validation Efficiency 96% (53/55)
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700010I14Rik T C 17: 8,995,234 S298P probably damaging Het
4930407I10Rik A G 15: 82,063,726 D608G possibly damaging Het
Actr10 T C 12: 70,952,985 V185A probably benign Het
Adam9 G A 8: 24,964,907 Q733* probably null Het
Adamts4 C T 1: 171,259,104 P822S probably benign Het
Arhgap9 G C 10: 127,328,465 R537P probably damaging Het
Bsn T A 9: 108,110,684 probably benign Het
Car5a A T 8: 121,944,749 H15Q probably benign Het
Disp1 A T 1: 183,089,386 I490N probably damaging Het
Dlgap5 T G 14: 47,413,788 Y96S probably damaging Het
Dnah10 T A 5: 124,730,137 V162D possibly damaging Het
Dock7 A T 4: 99,003,886 M821K possibly damaging Het
Exoc3l T C 8: 105,290,967 R528G probably damaging Het
Fam234b G A 6: 135,209,136 G17E unknown Het
Grhl2 G A 15: 37,360,823 G617D possibly damaging Het
Herc1 CTGAGGACTCTTTG CTG 9: 66,448,348 probably null Het
Hoxd9 C A 2: 74,695,687 probably benign Het
Hspa9 A G 18: 34,939,423 S550P probably damaging Het
Ide A C 19: 37,329,186 S63A unknown Het
Kat6b T A 14: 21,669,669 I1363N probably damaging Het
Ltbp1 T A 17: 75,291,367 C614* probably null Het
Mphosph8 A G 14: 56,674,465 D315G probably benign Het
Mthfr-ps1 A C 5: 78,474,483 noncoding transcript Het
Mug1 A G 6: 121,873,734 T730A probably benign Het
Myef2 T C 2: 125,115,479 T119A possibly damaging Het
Pald1 A G 10: 61,343,692 L466P probably damaging Het
Pcdh15 G A 10: 74,645,680 V286M probably damaging Het
Pcdhgb2 A G 18: 37,691,897 D647G probably damaging Het
Pdgfrb A C 18: 61,077,631 T737P probably benign Het
Pgk2 T G 17: 40,207,383 T385P probably benign Het
Pkp4 A G 2: 59,305,162 Y126C probably damaging Het
Plppr1 A G 4: 49,300,993 I109V probably benign Het
Ppcs A G 4: 119,421,909 F149L probably damaging Het
Ppp2r5d G A 17: 46,687,081 Q219* probably null Het
Raf1 C T 6: 115,623,054 probably null Het
Rfx7 C T 9: 72,616,643 R372W probably damaging Het
Robo4 C A 9: 37,405,581 S397R probably benign Het
Sat1 T C X: 155,215,186 probably benign Het
Serpina1c T C 12: 103,897,080 K287R probably benign Het
Sgsm2 T A 11: 74,892,028 H34L probably damaging Het
Slc38a4 A G 15: 96,998,493 Y498H probably damaging Het
Ttn T A 2: 76,798,040 Y14592F probably damaging Het
Ube3b T C 5: 114,398,428 F245S possibly damaging Het
Ugt3a2 G A 15: 9,335,793 probably null Het
Wdr91 T A 6: 34,904,522 S297C possibly damaging Het
Other mutations in Zcwpw2
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0329:Zcwpw2 UTSW 9 118014055 exon noncoding transcript
R0762:Zcwpw2 UTSW 9 118014114 exon noncoding transcript
R4651:Zcwpw2 UTSW 9 118014051 exon noncoding transcript
R4652:Zcwpw2 UTSW 9 118014051 exon noncoding transcript
Predicted Primers PCR Primer
(F):5'- CACGTTACCAGTGGAAGAGG -3'
(R):5'- CTACTTGCTTACTGTCTTTGAAAGG -3'

Sequencing Primer
(F):5'- GAGGAAAGCTGTTAAACTCTACAAC -3'
(R):5'- TGCTTACTGTCTTTGAAAGGTATAAG -3'
Posted On2015-06-20