Incidental Mutation 'R0010:Ylpm1'
| ID |
32504 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ylpm1
|
| Ensembl Gene |
ENSMUSG00000021244 |
| Gene Name |
YLP motif containing 1 |
| Synonyms |
A930013E17Rik, Zap3, ZAP |
| MMRRC Submission |
038305-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0010 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
12 |
| Chromosomal Location |
85043095-85117289 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 85075800 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Lysine
at position 384
(Q384K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000126347
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021670]
[ENSMUST00000101202]
[ENSMUST00000164558]
[ENSMUST00000168977]
|
| AlphaFold |
Q9R0I7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000021670
AA Change: Q842K
PolyPhen 2
Score 0.973 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000021670
Gene: ENSMUSG00000021244
AA Change: Q842K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
225 |
N/A |
INTRINSIC |
|
low complexity region
|
226 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
688 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
763 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
771 |
840 |
4.03e-5 |
PROSPERO |
|
low complexity region
|
841 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
966 |
972 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1062 |
1124 |
4.03e-5 |
PROSPERO |
|
low complexity region
|
1252 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1293 |
N/A |
INTRINSIC |
|
low complexity region
|
1326 |
1338 |
N/A |
INTRINSIC |
|
low complexity region
|
1339 |
1353 |
N/A |
INTRINSIC |
|
low complexity region
|
1408 |
1425 |
N/A |
INTRINSIC |
|
coiled coil region
|
1447 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1494 |
1517 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1532 |
N/A |
INTRINSIC |
|
low complexity region
|
1536 |
1557 |
N/A |
INTRINSIC |
|
low complexity region
|
1598 |
1630 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1694 |
N/A |
INTRINSIC |
|
low complexity region
|
1705 |
1717 |
N/A |
INTRINSIC |
|
low complexity region
|
1720 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
1797 |
1808 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1829 |
1990 |
7.8e-11 |
PFAM |
|
coiled coil region
|
1995 |
2032 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101202
|
| SMART Domains |
Protein: ENSMUSP00000098763
Gene: ENSMUSG00000021244
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
206 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
342 |
360 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
388 |
N/A |
INTRINSIC |
|
low complexity region
|
408 |
417 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
607 |
N/A |
INTRINSIC |
|
low complexity region
|
641 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
741 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
765 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
783 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
845 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
941 |
N/A |
INTRINSIC |
|
low complexity region
|
952 |
964 |
N/A |
INTRINSIC |
|
low complexity region
|
967 |
983 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1055 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1076 |
1265 |
4.9e-11 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000164558
AA Change: Q384K
PolyPhen 2
Score 0.973 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000126347
Gene: ENSMUSG00000021244
AA Change: Q384K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
80 |
196 |
N/A |
INTRINSIC |
|
low complexity region
|
230 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
293 |
305 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
514 |
N/A |
INTRINSIC |
|
low complexity region
|
794 |
808 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
880 |
N/A |
INTRINSIC |
|
low complexity region
|
881 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
967 |
N/A |
INTRINSIC |
|
coiled coil region
|
989 |
1016 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1060 |
1074 |
N/A |
INTRINSIC |
|
low complexity region
|
1078 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1140 |
1172 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1236 |
N/A |
INTRINSIC |
|
low complexity region
|
1247 |
1259 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1278 |
N/A |
INTRINSIC |
|
low complexity region
|
1339 |
1350 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1371 |
1559 |
5.2e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168977
|
| SMART Domains |
Protein: ENSMUSP00000128962
Gene: ENSMUSG00000021244
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
225 |
N/A |
INTRINSIC |
|
low complexity region
|
226 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
688 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
811 |
N/A |
INTRINSIC |
|
low complexity region
|
812 |
826 |
N/A |
INTRINSIC |
|
low complexity region
|
830 |
851 |
N/A |
INTRINSIC |
|
low complexity region
|
892 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
972 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
999 |
1011 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1030 |
N/A |
INTRINSIC |
|
low complexity region
|
1091 |
1102 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1123 |
1311 |
4.5e-11 |
PFAM |
|
| Meta Mutation Damage Score |
0.0838 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.9%
|
| Validation Efficiency |
100% (89/89) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrf3 |
T |
C |
5: 30,410,607 (GRCm39) |
|
probably benign |
Het |
| Ahrr |
G |
A |
13: 74,431,143 (GRCm39) |
|
probably benign |
Het |
| Aoc1l3 |
A |
T |
6: 48,965,840 (GRCm39) |
H616L |
probably damaging |
Het |
| Bbs7 |
T |
C |
3: 36,661,866 (GRCm39) |
|
probably null |
Het |
| Cacna1h |
T |
C |
17: 25,599,818 (GRCm39) |
K1566E |
probably damaging |
Het |
| Ccdc73 |
C |
T |
2: 104,811,332 (GRCm39) |
|
probably benign |
Het |
| Cd74 |
A |
T |
18: 60,942,143 (GRCm39) |
H124L |
probably benign |
Het |
| Cd74 |
A |
T |
18: 60,936,968 (GRCm39) |
|
probably benign |
Het |
| Cdk5rap2 |
T |
C |
4: 70,161,696 (GRCm39) |
E270G |
probably benign |
Het |
| Ces2a |
G |
A |
8: 105,468,028 (GRCm39) |
D520N |
probably benign |
Het |
| Cldnd1 |
T |
A |
16: 58,551,622 (GRCm39) |
|
probably benign |
Het |
| Cox17 |
T |
A |
16: 38,167,532 (GRCm39) |
C24S |
possibly damaging |
Het |
| Cyp2b9 |
T |
A |
7: 25,886,178 (GRCm39) |
|
probably benign |
Het |
| Dennd4a |
T |
C |
9: 64,803,997 (GRCm39) |
L1112P |
probably benign |
Het |
| Dennd4c |
T |
C |
4: 86,699,814 (GRCm39) |
S222P |
probably damaging |
Het |
| Dhx37 |
T |
A |
5: 125,508,680 (GRCm39) |
Q85L |
probably benign |
Het |
| Egfem1 |
G |
T |
3: 29,637,068 (GRCm39) |
C192F |
probably damaging |
Het |
| Eif3f |
A |
T |
7: 108,540,212 (GRCm39) |
N336Y |
possibly damaging |
Het |
| Evc2 |
T |
A |
5: 37,574,793 (GRCm39) |
L1016Q |
probably damaging |
Het |
| Fam114a2 |
G |
T |
11: 57,404,982 (GRCm39) |
T40N |
probably damaging |
Het |
| Fam135b |
T |
C |
15: 71,493,881 (GRCm39) |
K16R |
probably damaging |
Het |
| Fcho1 |
A |
G |
8: 72,162,643 (GRCm39) |
Y725H |
probably damaging |
Het |
| Frem1 |
T |
C |
4: 82,918,335 (GRCm39) |
I536V |
probably benign |
Het |
| Galnt2l |
G |
A |
8: 122,997,337 (GRCm39) |
|
probably benign |
Het |
| Ginm1 |
T |
C |
10: 7,651,138 (GRCm39) |
|
probably benign |
Het |
| Glrb |
A |
T |
3: 80,767,622 (GRCm39) |
|
probably benign |
Het |
| Glt6d1 |
C |
A |
2: 25,684,739 (GRCm39) |
|
probably null |
Het |
| Gm10320 |
T |
C |
13: 98,626,054 (GRCm39) |
Y110C |
probably damaging |
Het |
| Gm3985 |
A |
T |
8: 33,432,484 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5422 |
A |
G |
10: 31,125,750 (GRCm39) |
|
noncoding transcript |
Het |
| Igkv6-29 |
A |
T |
6: 70,115,754 (GRCm39) |
|
probably benign |
Het |
| Inpp5d |
G |
A |
1: 87,625,268 (GRCm39) |
|
probably null |
Het |
| Itpr3 |
T |
G |
17: 27,339,951 (GRCm39) |
V2610G |
probably damaging |
Het |
| Kmt5c |
T |
A |
7: 4,749,207 (GRCm39) |
M88K |
probably benign |
Het |
| Lrp12 |
C |
T |
15: 39,741,672 (GRCm39) |
A367T |
probably damaging |
Het |
| Ltbp1 |
A |
G |
17: 75,670,386 (GRCm39) |
T1476A |
probably damaging |
Het |
| Mcoln2 |
C |
T |
3: 145,889,316 (GRCm39) |
T374M |
probably damaging |
Het |
| Milr1 |
T |
G |
11: 106,657,829 (GRCm39) |
*209G |
probably null |
Het |
| Mitf |
A |
G |
6: 97,784,242 (GRCm39) |
K33R |
probably benign |
Het |
| Mon2 |
A |
C |
10: 122,868,599 (GRCm39) |
S485A |
probably damaging |
Het |
| Mpdu1 |
C |
T |
11: 69,549,667 (GRCm39) |
G47R |
probably damaging |
Het |
| Ms4a4d |
A |
G |
19: 11,532,190 (GRCm39) |
N112S |
probably damaging |
Het |
| Mybpc3 |
G |
A |
2: 90,965,178 (GRCm39) |
W1082* |
probably null |
Het |
| Myl3 |
A |
C |
9: 110,596,997 (GRCm39) |
D119A |
probably damaging |
Het |
| Naa15 |
A |
T |
3: 51,343,634 (GRCm39) |
|
probably null |
Het |
| Nav3 |
A |
G |
10: 109,659,087 (GRCm39) |
|
probably benign |
Het |
| Nek7 |
T |
A |
1: 138,471,942 (GRCm39) |
Q66L |
possibly damaging |
Het |
| Nktr |
G |
A |
9: 121,570,232 (GRCm39) |
|
probably benign |
Het |
| Nlgn1 |
G |
T |
3: 25,490,006 (GRCm39) |
|
probably benign |
Het |
| Npr1 |
T |
C |
3: 90,362,139 (GRCm39) |
E1002G |
probably damaging |
Het |
| Nup133 |
A |
T |
8: 124,631,318 (GRCm39) |
I1072N |
probably damaging |
Het |
| Oc90 |
C |
T |
15: 65,748,397 (GRCm39) |
C371Y |
probably damaging |
Het |
| Or5ak24 |
A |
T |
2: 85,260,239 (GRCm39) |
D311E |
probably benign |
Het |
| Or7g20 |
A |
T |
9: 18,946,618 (GRCm39) |
L66F |
probably damaging |
Het |
| Or8b42 |
A |
T |
9: 38,342,216 (GRCm39) |
I213F |
possibly damaging |
Het |
| Pradc1 |
A |
T |
6: 85,424,213 (GRCm39) |
N44K |
probably damaging |
Het |
| Pradc1 |
T |
C |
6: 85,424,602 (GRCm39) |
D116G |
probably damaging |
Het |
| Ptprk |
G |
A |
10: 28,461,965 (GRCm39) |
C91Y |
probably damaging |
Het |
| Pus7 |
T |
C |
5: 23,952,843 (GRCm39) |
I491V |
probably benign |
Het |
| Rock1 |
T |
A |
18: 10,084,380 (GRCm39) |
D951V |
probably damaging |
Het |
| Scgb2b26 |
T |
A |
7: 33,643,774 (GRCm39) |
E55D |
probably damaging |
Het |
| Scn8a |
T |
C |
15: 100,911,454 (GRCm39) |
V958A |
probably damaging |
Het |
| Sec14l1 |
T |
C |
11: 117,034,596 (GRCm39) |
|
probably benign |
Het |
| Sec24c |
A |
G |
14: 20,739,329 (GRCm39) |
|
probably benign |
Het |
| Sema6b |
C |
T |
17: 56,431,105 (GRCm39) |
E853K |
probably benign |
Het |
| Sgk1 |
G |
A |
10: 21,873,337 (GRCm39) |
|
probably null |
Het |
| Shprh |
C |
T |
10: 11,027,675 (GRCm39) |
T94I |
probably benign |
Het |
| Slc16a3 |
T |
C |
11: 120,847,531 (GRCm39) |
S240P |
probably benign |
Het |
| Slc5a8 |
T |
C |
10: 88,722,452 (GRCm39) |
V95A |
probably benign |
Het |
| Smg1 |
A |
T |
7: 117,771,082 (GRCm39) |
|
probably benign |
Het |
| Spta1 |
G |
A |
1: 174,045,509 (GRCm39) |
V1556I |
probably benign |
Het |
| Trappc14 |
T |
C |
5: 138,258,555 (GRCm39) |
|
probably null |
Het |
| Trappc4 |
G |
A |
9: 44,316,528 (GRCm39) |
|
probably benign |
Het |
| Tubgcp6 |
A |
G |
15: 88,987,386 (GRCm39) |
S1188P |
probably benign |
Het |
| Txlna |
T |
G |
4: 129,522,879 (GRCm39) |
D487A |
probably benign |
Het |
| Ube2d2b |
T |
C |
5: 107,978,502 (GRCm39) |
F51S |
possibly damaging |
Het |
| Vmn2r6 |
G |
A |
3: 64,466,966 (GRCm39) |
Q178* |
probably null |
Het |
| Wdfy3 |
T |
C |
5: 101,996,215 (GRCm39) |
T3234A |
probably damaging |
Het |
| Zbtb41 |
T |
G |
1: 139,351,268 (GRCm39) |
V127G |
probably damaging |
Het |
| Zfp605 |
T |
A |
5: 110,275,400 (GRCm39) |
C173S |
probably benign |
Het |
| Zfp608 |
A |
T |
18: 55,028,286 (GRCm39) |
|
probably benign |
Het |
| Zhx2 |
T |
C |
15: 57,684,670 (GRCm39) |
V13A |
possibly damaging |
Het |
|
| Other mutations in Ylpm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00539:Ylpm1
|
APN |
12 |
85,075,728 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL00809:Ylpm1
|
APN |
12 |
85,095,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01508:Ylpm1
|
APN |
12 |
85,062,229 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL02199:Ylpm1
|
APN |
12 |
85,080,779 (GRCm39) |
nonsense |
probably null |
|
|
IGL02392:Ylpm1
|
APN |
12 |
85,061,731 (GRCm39) |
missense |
unknown |
|
|
IGL02455:Ylpm1
|
APN |
12 |
85,077,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02506:Ylpm1
|
APN |
12 |
85,095,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Ylpm1
|
APN |
12 |
85,096,032 (GRCm39) |
splice site |
probably benign |
|
|
I1329:Ylpm1
|
UTSW |
12 |
85,087,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02799:Ylpm1
|
UTSW |
12 |
85,091,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0090:Ylpm1
|
UTSW |
12 |
85,075,814 (GRCm39) |
intron |
probably benign |
|
|
R0149:Ylpm1
|
UTSW |
12 |
85,075,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0226:Ylpm1
|
UTSW |
12 |
85,096,511 (GRCm39) |
missense |
probably benign |
0.21 |
|
R0375:Ylpm1
|
UTSW |
12 |
85,061,754 (GRCm39) |
missense |
unknown |
|
|
R0378:Ylpm1
|
UTSW |
12 |
85,043,850 (GRCm39) |
intron |
probably benign |
|
|
R0507:Ylpm1
|
UTSW |
12 |
85,075,886 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0742:Ylpm1
|
UTSW |
12 |
85,075,886 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1350:Ylpm1
|
UTSW |
12 |
85,060,856 (GRCm39) |
unclassified |
probably benign |
|
|
R1452:Ylpm1
|
UTSW |
12 |
85,077,157 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1500:Ylpm1
|
UTSW |
12 |
85,061,770 (GRCm39) |
missense |
unknown |
|
|
R1837:Ylpm1
|
UTSW |
12 |
85,076,107 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1945:Ylpm1
|
UTSW |
12 |
85,062,192 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1971:Ylpm1
|
UTSW |
12 |
85,087,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2211:Ylpm1
|
UTSW |
12 |
85,091,152 (GRCm39) |
nonsense |
probably null |
|
|
R2213:Ylpm1
|
UTSW |
12 |
85,116,492 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2269:Ylpm1
|
UTSW |
12 |
85,061,824 (GRCm39) |
missense |
unknown |
|
|
R2300:Ylpm1
|
UTSW |
12 |
85,107,093 (GRCm39) |
splice site |
probably null |
|
|
R2439:Ylpm1
|
UTSW |
12 |
85,060,891 (GRCm39) |
unclassified |
probably benign |
|
|
R2497:Ylpm1
|
UTSW |
12 |
85,043,535 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2890:Ylpm1
|
UTSW |
12 |
85,076,587 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3111:Ylpm1
|
UTSW |
12 |
85,076,145 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3436:Ylpm1
|
UTSW |
12 |
85,096,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3437:Ylpm1
|
UTSW |
12 |
85,096,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4156:Ylpm1
|
UTSW |
12 |
85,104,177 (GRCm39) |
intron |
probably benign |
|
|
R4157:Ylpm1
|
UTSW |
12 |
85,104,177 (GRCm39) |
intron |
probably benign |
|
|
R4959:Ylpm1
|
UTSW |
12 |
85,096,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5014:Ylpm1
|
UTSW |
12 |
85,061,523 (GRCm39) |
missense |
unknown |
|
|
R5039:Ylpm1
|
UTSW |
12 |
85,089,013 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Ylpm1
|
UTSW |
12 |
85,062,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5084:Ylpm1
|
UTSW |
12 |
85,076,095 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5325:Ylpm1
|
UTSW |
12 |
85,060,735 (GRCm39) |
unclassified |
probably benign |
|
|
R5378:Ylpm1
|
UTSW |
12 |
85,077,029 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5428:Ylpm1
|
UTSW |
12 |
85,077,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5467:Ylpm1
|
UTSW |
12 |
85,043,633 (GRCm39) |
missense |
unknown |
|
|
R5605:Ylpm1
|
UTSW |
12 |
85,075,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5614:Ylpm1
|
UTSW |
12 |
85,111,718 (GRCm39) |
intron |
probably benign |
|
|
R5748:Ylpm1
|
UTSW |
12 |
85,107,025 (GRCm39) |
splice site |
probably null |
|
|
R5860:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5861:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5881:Ylpm1
|
UTSW |
12 |
85,088,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5912:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5915:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6000:Ylpm1
|
UTSW |
12 |
85,044,030 (GRCm39) |
missense |
unknown |
|
|
R6004:Ylpm1
|
UTSW |
12 |
85,075,858 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6007:Ylpm1
|
UTSW |
12 |
85,076,064 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6053:Ylpm1
|
UTSW |
12 |
85,043,277 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6104:Ylpm1
|
UTSW |
12 |
85,076,404 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6197:Ylpm1
|
UTSW |
12 |
85,088,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6293:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6297:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6305:Ylpm1
|
UTSW |
12 |
85,077,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6379:Ylpm1
|
UTSW |
12 |
85,077,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6465:Ylpm1
|
UTSW |
12 |
85,096,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6608:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6609:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6737:Ylpm1
|
UTSW |
12 |
85,077,620 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6794:Ylpm1
|
UTSW |
12 |
85,043,655 (GRCm39) |
missense |
unknown |
|
|
R7383:Ylpm1
|
UTSW |
12 |
85,091,242 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7514:Ylpm1
|
UTSW |
12 |
85,077,268 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7577:Ylpm1
|
UTSW |
12 |
85,043,994 (GRCm39) |
missense |
unknown |
|
|
R7709:Ylpm1
|
UTSW |
12 |
85,059,799 (GRCm39) |
missense |
unknown |
|
|
R7718:Ylpm1
|
UTSW |
12 |
85,075,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7736:Ylpm1
|
UTSW |
12 |
85,059,757 (GRCm39) |
missense |
unknown |
|
|
R7758:Ylpm1
|
UTSW |
12 |
85,061,796 (GRCm39) |
missense |
unknown |
|
|
R7807:Ylpm1
|
UTSW |
12 |
85,060,855 (GRCm39) |
nonsense |
probably null |
|
|
R7838:Ylpm1
|
UTSW |
12 |
85,095,640 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7846:Ylpm1
|
UTSW |
12 |
85,104,042 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8170:Ylpm1
|
UTSW |
12 |
85,080,801 (GRCm39) |
missense |
probably benign |
0.40 |
|
R8776:Ylpm1
|
UTSW |
12 |
85,077,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8776-TAIL:Ylpm1
|
UTSW |
12 |
85,077,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8812:Ylpm1
|
UTSW |
12 |
85,043,566 (GRCm39) |
missense |
unknown |
|
|
R8847:Ylpm1
|
UTSW |
12 |
85,061,672 (GRCm39) |
missense |
unknown |
|
|
R8874:Ylpm1
|
UTSW |
12 |
85,116,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Ylpm1
|
UTSW |
12 |
85,104,052 (GRCm39) |
missense |
|
|
|
R9165:Ylpm1
|
UTSW |
12 |
85,077,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9198:Ylpm1
|
UTSW |
12 |
85,080,689 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9564:Ylpm1
|
UTSW |
12 |
85,091,176 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9629:Ylpm1
|
UTSW |
12 |
85,044,036 (GRCm39) |
missense |
unknown |
|
|
R9797:Ylpm1
|
UTSW |
12 |
85,077,109 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1088:Ylpm1
|
UTSW |
12 |
85,076,929 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Ylpm1
|
UTSW |
12 |
85,077,058 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Ylpm1
|
UTSW |
12 |
85,104,057 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCAAGCACTGCTGCCTTAACG -3'
(R):5'- CTGAGCTGCCTTGGTATCCTTGAC -3'
Sequencing Primer
(F):5'- CGTTTTGAAGGAAATCGCCC -3'
(R):5'- TGGTATCCTTGACATCTGCG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation