Incidental Mutation 'R4380:2310016G11Rik'
ID325296
Institutional Source Beutler Lab
Gene Symbol 2310016G11Rik
Ensembl Gene ENSMUSG00000070574
Gene NameRIKEN cDNA 2310016G11 gene
Synonyms
MMRRC Submission 041678-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.224) question?
Stock #R4380 (G1)
Quality Score225
Status Validated
Chromosome7
Chromosomal Location44676965-44678235 bp(+) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) T to C at 44677156 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000094460
SMART Domains Protein: ENSMUSP00000092031
Gene: ENSMUSG00000070574

DomainStartEndE-ValueType
Blast:HOX 14 79 8e-10 BLAST
Predicted Effect noncoding transcript
Transcript: ENSMUST00000209111
Meta Mutation Damage Score 0.1072 question?
Coding Region Coverage
  • 1x: 99.2%
  • 3x: 98.6%
  • 10x: 97.1%
  • 20x: 94.7%
Validation Efficiency 98% (45/46)
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Casc3 C A 11: 98,823,031 P363Q possibly damaging Het
Cep162 C A 9: 87,200,003 R1283L probably damaging Het
Clk3 C A 9: 57,751,792 W562L probably damaging Het
Col17a1 G A 19: 47,657,090 T844M possibly damaging Het
Dntt G C 19: 41,053,233 G452A probably damaging Het
Dopey2 G A 16: 93,716,232 V20I possibly damaging Het
Dst T C 1: 34,163,235 S215P probably damaging Het
Dync1li2 A T 8: 104,428,166 I270N probably damaging Het
Egflam A T 15: 7,243,869 I575N possibly damaging Het
Gldc G T 19: 30,160,768 probably benign Het
Gm13089 T A 4: 143,698,286 I196F probably benign Het
Gm17067 C A 7: 42,708,038 V347L probably benign Het
Gmds T A 13: 31,917,696 N304I probably benign Het
Grm7 G T 6: 110,646,348 V161F probably damaging Het
Igfn1 T C 1: 135,967,771 T1686A probably benign Het
Klk14 G A 7: 43,692,077 C51Y probably damaging Het
Lamb3 A T 1: 193,331,375 Q519L probably benign Het
Lrp10 C T 14: 54,468,366 R338C probably damaging Het
Macf1 A G 4: 123,354,492 probably benign Het
Mcfd2 C G 17: 87,257,959 G39R possibly damaging Het
Mecom T C 3: 29,987,070 H125R probably damaging Het
Nme7 A G 1: 164,345,238 T173A probably benign Het
Olfr1193 A G 2: 88,678,271 T132A possibly damaging Het
Olfr194 C T 16: 59,119,664 M135I probably benign Het
Pde1c T A 6: 56,072,278 R683S probably null Het
Pkn2 A T 3: 142,830,456 probably benign Het
Plppr4 T G 3: 117,322,397 T604P probably benign Het
Slc34a2 C T 5: 53,069,286 P584S probably damaging Het
Slco5a1 A T 1: 12,939,168 M361K probably damaging Het
Snx4 T A 16: 33,264,296 I60N probably damaging Het
Sp6 T C 11: 97,021,746 L95P probably damaging Het
Stat5b A G 11: 100,787,349 F646S probably damaging Het
Tbc1d1 T C 5: 64,333,548 M785T probably benign Het
Tbc1d22a T A 15: 86,351,734 C365S probably damaging Het
Tle1 ACAGGTTTCTTCAGGTTTCTT ACAGGTTTCTT 4: 72,118,163 probably benign Het
Tnfsf8 A T 4: 63,861,027 C11* probably null Het
Ttn A T 2: 76,918,141 V4188E probably damaging Het
Ugt2b5 T A 5: 87,127,894 H366L probably damaging Het
Wdr17 T C 8: 54,648,407 probably benign Het
Zfhx3 A G 8: 108,956,390 Y3487C unknown Het
Zfp28 C T 7: 6,393,442 T292I probably benign Het
Other mutations in 2310016G11Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0021:2310016G11Rik UTSW 7 44677196 intron noncoding transcript
R0021:2310016G11Rik UTSW 7 44677196 intron noncoding transcript
R0863:2310016G11Rik UTSW 7 44677808 exon noncoding transcript
R5110:2310016G11Rik UTSW 7 44677862 exon noncoding transcript
Predicted Primers PCR Primer
(F):5'- GAGATGAGAAACTCCCCAGC -3'
(R):5'- TTGTGCCAGAGGATTGGAAAC -3'

Sequencing Primer
(F):5'- TCCCCAGCTAATCTGAAGAAGG -3'
(R):5'- CATTAAACGAATTCTTAGGCCAGAG -3'
Posted On2015-07-06