Mutagenetix > Incidental Mutation

Incidental Mutation 'R4348:Dnah12'

328413

Institutional Source

Beutler Lab

Gene Symbol

Dnah12

Ensembl Gene

ENSMUSG00000021879

Gene Name

dynein, axonemal, heavy chain 12

Synonyms

HL19, DHC3, Dnahc7l, 4921531P07Rik, HL-19, LOC380889, Hdhc3, Dnahc12, DLP12

MMRRC Submission

041103-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.187) question?

Stock #

R4348 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

26414429-26613660 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 26536498 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Lysine at position 2138 (M2138K)

Ref Sequence

ENSEMBL: ENSMUSP00000022433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022433]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000022433
AA Change: M2138K

PolyPhen 2 Score 0.935 (Sensitivity: 0.80; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000022433
Gene: ENSMUSG00000021879
AA Change: M2138K

Domain	Start	End	E-Value	Type
low complexity region	127	140	N/A	INTRINSIC
coiled coil region	588	666	N/A	INTRINSIC
Pfam:DHC_N2	676	1113	1.1e-147	PFAM
AAA	1268	1407	1.15e0	SMART
Pfam:AAA_5	1552	1695	1.5e-7	PFAM
Blast:AAA	1709	1827	2e-24	BLAST
Blast:AAA	1848	1898	1e-16	BLAST
AAA	1903	2051	5.42e-4	SMART
Pfam:AAA_8	2238	2316	2e-18	PFAM

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.3%
20x: 95.3%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2ml1	C	T	6: 128,557,349 (GRCm39)	A115T	probably benign	Het
Aass	A	G	6: 23,113,738 (GRCm39)	F235L	probably benign	Het
Adamts1	T	A	16: 85,599,234 (GRCm39)	D122V	probably benign	Het
Adcy6	A	T	15: 98,502,041 (GRCm39)	V191E	probably benign	Het
Cngb3	G	A	4: 19,396,688 (GRCm39)	R347Q	probably damaging	Het
Cntnap4	T	A	8: 113,480,554 (GRCm39)	C334S	probably damaging	Het
D7Ertd443e	ACCTAGGAGGTCCT	ACCT	7: 133,950,682 (GRCm39)		probably null	Het
Ebf2	T	C	14: 67,476,871 (GRCm39)	I138T	probably damaging	Het
Ect2l	A	G	10: 18,012,736 (GRCm39)	S784P	probably damaging	Het
Emilin2	T	C	17: 71,587,726 (GRCm39)	M129V	probably benign	Het
Enah	A	T	1: 181,749,985 (GRCm39)	S266T	possibly damaging	Het
Fhip1b	A	G	7: 105,034,556 (GRCm39)	V422A	probably damaging	Het
Garem2	G	A	5: 30,310,366 (GRCm39)	R26H	possibly damaging	Het
Gfy	T	C	7: 44,827,040 (GRCm39)	E352G	probably benign	Het
Gpatch11	T	C	17: 79,148,446 (GRCm39)	L128P	probably damaging	Het
Inava	C	T	1: 136,153,946 (GRCm39)	V180I	probably damaging	Het
Kcns3	T	C	12: 11,141,382 (GRCm39)	N439S	possibly damaging	Het
Llgl1	C	T	11: 60,600,394 (GRCm39)	P581L	probably benign	Het
Mbd1	G	T	18: 74,407,487 (GRCm39)	R199L	probably damaging	Het
Mbd5	T	A	2: 49,146,339 (GRCm39)	M183K	probably benign	Het
Mecom	C	A	3: 30,020,887 (GRCm39)	V452L	possibly damaging	Het
Nckap1l	A	G	15: 103,395,246 (GRCm39)	T909A	probably damaging	Het
Ntrk2	A	G	13: 59,026,073 (GRCm39)	K464E	probably damaging	Het
Orc1	C	T	4: 108,450,649 (GRCm39)	T127I	probably damaging	Het
Pcdh17	T	C	14: 84,685,060 (GRCm39)	I509T	probably damaging	Het
Pcsk7	G	A	9: 45,830,646 (GRCm39)	A475T	probably damaging	Het
Prb1b	T	G	6: 132,290,624 (GRCm39)	Y25S	unknown	Het
Prdm16	A	G	4: 154,561,124 (GRCm39)	V136A	probably benign	Het
Ptch1	C	T	13: 63,682,143 (GRCm39)	R537H	probably damaging	Het
Ptpn13	T	A	5: 103,717,592 (GRCm39)	S1879R	probably damaging	Het
Rasgrp3	A	T	17: 75,818,975 (GRCm39)	Q388L	probably benign	Het
Rnf31	AAC	A	14: 55,838,555 (GRCm39)		probably null	Het
Rnf38	A	T	4: 44,149,100 (GRCm39)	N82K	possibly damaging	Het
Smco3	T	A	6: 136,808,692 (GRCm39)	T61S	possibly damaging	Het
Ssx2ip	T	C	3: 146,138,245 (GRCm39)	V364A	probably benign	Het
Ttn	A	G	2: 76,595,109 (GRCm39)	I20347T	possibly damaging	Het
Vmn2r120	A	T	17: 57,829,466 (GRCm39)	F477Y	possibly damaging	Het
Wee1	A	G	7: 109,730,165 (GRCm39)	H423R	probably damaging	Het

Other mutations in Dnah12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01412:Dnah12	APN	14	26,492,962 (GRCm39)	missense	probably damaging	1.00
IGL01602:Dnah12	APN	14	26,431,430 (GRCm39)	splice site	probably benign
IGL01681:Dnah12	APN	14	26,443,315 (GRCm39)	missense	probably benign
IGL02082:Dnah12	APN	14	26,428,317 (GRCm39)	missense	possibly damaging	0.79
IGL02140:Dnah12	APN	14	26,437,732 (GRCm39)	missense	probably benign	0.20
IGL02170:Dnah12	APN	14	26,495,069 (GRCm39)	missense	probably damaging	0.99
IGL02174:Dnah12	APN	14	26,428,072 (GRCm39)	missense	probably benign	0.00
IGL02367:Dnah12	APN	14	26,430,316 (GRCm39)	missense	probably benign	0.30
IGL02418:Dnah12	APN	14	26,495,679 (GRCm39)	missense	probably damaging	1.00
IGL03039:Dnah12	APN	14	26,445,667 (GRCm39)	missense	probably benign	0.02
IGL03066:Dnah12	APN	14	26,418,553 (GRCm39)	missense	probably benign	0.06
drippings	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
grueben	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
BB010:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
BB020:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
F5770:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
FR4304:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4340:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4342:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4589:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
IGL03055:Dnah12	UTSW	14	26,594,697 (GRCm39)	missense	probably damaging	1.00
LCD18:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
R0003:Dnah12	UTSW	14	26,494,601 (GRCm39)	missense	probably damaging	1.00
R0110:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0302:Dnah12	UTSW	14	26,521,956 (GRCm39)	missense	probably damaging	1.00
R0355:Dnah12	UTSW	14	26,427,272 (GRCm39)	splice site	probably null
R0364:Dnah12	UTSW	14	26,445,628 (GRCm39)	missense	probably benign	0.10
R0469:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0558:Dnah12	UTSW	14	26,430,465 (GRCm39)	missense	probably benign	0.00
R0709:Dnah12	UTSW	14	26,606,222 (GRCm39)	splice site	probably benign
R0734:Dnah12	UTSW	14	26,521,970 (GRCm39)	missense	probably benign	0.00
R1273:Dnah12	UTSW	14	26,460,375 (GRCm39)	nonsense	probably null
R1496:Dnah12	UTSW	14	26,431,403 (GRCm39)	missense	probably benign
R1503:Dnah12	UTSW	14	26,495,649 (GRCm39)	missense	probably damaging	1.00
R1535:Dnah12	UTSW	14	26,538,279 (GRCm39)	missense	possibly damaging	0.91
R1608:Dnah12	UTSW	14	26,488,147 (GRCm39)	missense	probably damaging	1.00
R1682:Dnah12	UTSW	14	26,500,840 (GRCm39)	missense	possibly damaging	0.71
R1758:Dnah12	UTSW	14	26,488,071 (GRCm39)	missense	probably benign	0.02
R1826:Dnah12	UTSW	14	26,432,174 (GRCm39)	missense	probably benign	0.01
R1829:Dnah12	UTSW	14	26,522,032 (GRCm39)	missense	probably damaging	1.00
R1829:Dnah12	UTSW	14	26,494,980 (GRCm39)	missense	probably damaging	1.00
R1862:Dnah12	UTSW	14	26,430,412 (GRCm39)	missense	probably benign	0.30
R1862:Dnah12	UTSW	14	26,418,553 (GRCm39)	missense	probably benign	0.06
R1913:Dnah12	UTSW	14	26,514,221 (GRCm39)	splice site	probably null
R1933:Dnah12	UTSW	14	26,455,650 (GRCm39)	missense	probably damaging	0.98
R2006:Dnah12	UTSW	14	26,536,416 (GRCm39)	missense	possibly damaging	0.95
R2045:Dnah12	UTSW	14	26,503,485 (GRCm39)	missense	probably null	1.00
R2113:Dnah12	UTSW	14	26,488,098 (GRCm39)	missense	probably damaging	1.00
R2125:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2126:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2207:Dnah12	UTSW	14	26,503,744 (GRCm39)	missense	probably damaging	0.99
R2213:Dnah12	UTSW	14	26,460,485 (GRCm39)	missense	probably benign	0.06
R2511:Dnah12	UTSW	14	26,491,907 (GRCm39)	missense	possibly damaging	0.65
R2875:Dnah12	UTSW	14	26,598,907 (GRCm39)	missense	probably benign	0.05
R2875:Dnah12	UTSW	14	26,414,625 (GRCm39)	missense	probably benign	0.04
R3551:Dnah12	UTSW	14	26,492,929 (GRCm39)	missense	probably benign	0.01
R3713:Dnah12	UTSW	14	26,534,747 (GRCm39)	missense	probably benign
R3729:Dnah12	UTSW	14	26,427,220 (GRCm39)	missense	probably benign	0.02
R3799:Dnah12	UTSW	14	26,492,880 (GRCm39)	missense	probably damaging	1.00
R3846:Dnah12	UTSW	14	26,431,366 (GRCm39)	missense	probably benign	0.00
R3892:Dnah12	UTSW	14	26,578,573 (GRCm39)	missense	probably benign	0.03
R3921:Dnah12	UTSW	14	26,493,008 (GRCm39)	missense	probably damaging	1.00
R3940:Dnah12	UTSW	14	26,444,754 (GRCm39)	missense	probably benign
R4065:Dnah12	UTSW	14	26,492,405 (GRCm39)	missense	probably benign	0.02
R4113:Dnah12	UTSW	14	26,414,722 (GRCm39)	missense	probably damaging	0.98
R4249:Dnah12	UTSW	14	26,430,341 (GRCm39)	missense	possibly damaging	0.70
R4259:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4260:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4457:Dnah12	UTSW	14	26,537,464 (GRCm39)	missense	probably damaging	1.00
R4490:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4491:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4494:Dnah12	UTSW	14	26,593,812 (GRCm39)	missense	probably damaging	0.99
R4523:Dnah12	UTSW	14	26,598,915 (GRCm39)	missense	possibly damaging	0.83
R4523:Dnah12	UTSW	14	26,491,979 (GRCm39)	missense	probably damaging	0.97
R4546:Dnah12	UTSW	14	26,494,971 (GRCm39)	missense	probably damaging	1.00
R4584:Dnah12	UTSW	14	26,494,551 (GRCm39)	missense	probably damaging	1.00
R4624:Dnah12	UTSW	14	26,456,913 (GRCm39)	missense	possibly damaging	0.82
R4689:Dnah12	UTSW	14	26,427,994 (GRCm39)	missense	probably benign	0.00
R4727:Dnah12	UTSW	14	26,594,274 (GRCm39)	missense	probably damaging	1.00
R4732:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4733:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4851:Dnah12	UTSW	14	26,437,784 (GRCm39)	nonsense	probably null
R4879:Dnah12	UTSW	14	26,439,201 (GRCm39)	critical splice donor site	probably null
R4893:Dnah12	UTSW	14	26,431,325 (GRCm39)	missense	possibly damaging	0.66
R4915:Dnah12	UTSW	14	26,455,725 (GRCm39)	missense	probably damaging	1.00
R4927:Dnah12	UTSW	14	26,583,762 (GRCm39)	nonsense	probably null
R4939:Dnah12	UTSW	14	26,613,481 (GRCm39)	missense	probably damaging	1.00
R4962:Dnah12	UTSW	14	26,437,855 (GRCm39)	missense	probably benign	0.00
R5011:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5013:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5043:Dnah12	UTSW	14	26,606,147 (GRCm39)	missense	probably damaging	1.00
R5049:Dnah12	UTSW	14	26,456,852 (GRCm39)	missense	probably benign	0.09
R5122:Dnah12	UTSW	14	26,439,155 (GRCm39)	missense	probably benign	0.00
R5135:Dnah12	UTSW	14	26,492,434 (GRCm39)	missense	probably damaging	0.99
R5149:Dnah12	UTSW	14	26,572,883 (GRCm39)	nonsense	probably null
R5154:Dnah12	UTSW	14	26,571,320 (GRCm39)	missense	probably benign	0.12
R5206:Dnah12	UTSW	14	26,491,942 (GRCm39)	missense	probably damaging	1.00
R5307:Dnah12	UTSW	14	26,414,641 (GRCm39)	missense	possibly damaging	0.49
R5330:Dnah12	UTSW	14	26,495,787 (GRCm39)	missense	probably damaging	1.00
R5335:Dnah12	UTSW	14	26,601,695 (GRCm39)	missense	probably damaging	1.00
R5339:Dnah12	UTSW	14	26,536,494 (GRCm39)	missense	possibly damaging	0.83
R5354:Dnah12	UTSW	14	26,496,299 (GRCm39)	splice site	probably null
R5389:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R5434:Dnah12	UTSW	14	26,581,256 (GRCm39)	missense	probably damaging	1.00
R5466:Dnah12	UTSW	14	26,493,007 (GRCm39)	missense	probably damaging	1.00
R5655:Dnah12	UTSW	14	26,431,424 (GRCm39)	missense	probably benign	0.01
R5681:Dnah12	UTSW	14	26,537,452 (GRCm39)	missense	probably benign	0.32
R5824:Dnah12	UTSW	14	26,492,475 (GRCm39)	critical splice donor site	probably null
R5863:Dnah12	UTSW	14	26,576,878 (GRCm39)	missense	probably damaging	1.00
R5890:Dnah12	UTSW	14	26,428,039 (GRCm39)	missense	probably benign	0.09
R5912:Dnah12	UTSW	14	26,491,965 (GRCm39)	nonsense	probably null
R5916:Dnah12	UTSW	14	26,428,073 (GRCm39)	missense	possibly damaging	0.92
R5941:Dnah12	UTSW	14	26,428,022 (GRCm39)	missense	probably benign	0.00
R5987:Dnah12	UTSW	14	26,608,828 (GRCm39)	missense	possibly damaging	0.54
R5992:Dnah12	UTSW	14	26,418,496 (GRCm39)	missense	probably benign	0.04
R6132:Dnah12	UTSW	14	26,439,066 (GRCm39)	missense	probably damaging	1.00
R6136:Dnah12	UTSW	14	26,597,227 (GRCm39)	missense	probably damaging	0.99
R6158:Dnah12	UTSW	14	26,495,642 (GRCm39)	missense	possibly damaging	0.95
R6183:Dnah12	UTSW	14	26,583,726 (GRCm39)	missense	probably damaging	1.00
R6191:Dnah12	UTSW	14	26,431,412 (GRCm39)	missense	probably benign	0.03
R6235:Dnah12	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
R6277:Dnah12	UTSW	14	26,492,439 (GRCm39)	missense	probably damaging	1.00
R6332:Dnah12	UTSW	14	26,439,129 (GRCm39)	missense	probably damaging	0.99
R6334:Dnah12	UTSW	14	26,427,989 (GRCm39)	missense	possibly damaging	0.51
R6443:Dnah12	UTSW	14	26,600,008 (GRCm39)	missense	probably benign	0.06
R6480:Dnah12	UTSW	14	26,594,412 (GRCm39)	missense	probably damaging	1.00
R6530:Dnah12	UTSW	14	26,456,865 (GRCm39)	missense	probably damaging	1.00
R6678:Dnah12	UTSW	14	26,456,847 (GRCm39)	missense	probably damaging	1.00
R6709:Dnah12	UTSW	14	26,594,706 (GRCm39)	missense	probably damaging	1.00
R6724:Dnah12	UTSW	14	26,518,180 (GRCm39)	missense	probably benign	0.02
R6745:Dnah12	UTSW	14	26,428,383 (GRCm39)	missense	probably damaging	0.99
R6788:Dnah12	UTSW	14	26,523,470 (GRCm39)	missense	probably damaging	0.99
R6894:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R6912:Dnah12	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
R6982:Dnah12	UTSW	14	26,521,033 (GRCm39)	splice site	probably null
R7001:Dnah12	UTSW	14	26,601,681 (GRCm39)	missense	probably damaging	0.99
R7002:Dnah12	UTSW	14	26,598,955 (GRCm39)	missense	probably damaging	1.00
R7017:Dnah12	UTSW	14	26,456,835 (GRCm39)	missense	probably benign
R7107:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7108:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7121:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7122:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,523,370 (GRCm39)	missense	probably damaging	0.99
R7150:Dnah12	UTSW	14	26,583,689 (GRCm39)	missense	probably damaging	0.99
R7188:Dnah12	UTSW	14	26,536,370 (GRCm39)	missense	probably benign	0.04
R7201:Dnah12	UTSW	14	26,536,579 (GRCm39)	missense	probably benign	0.08
R7202:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7204:Dnah12	UTSW	14	26,503,442 (GRCm39)	missense	probably damaging	0.99
R7204:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7205:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7206:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7219:Dnah12	UTSW	14	26,576,837 (GRCm39)	missense	probably damaging	0.99
R7337:Dnah12	UTSW	14	26,488,534 (GRCm39)	splice site	probably null
R7339:Dnah12	UTSW	14	26,594,277 (GRCm39)	missense	probably benign
R7363:Dnah12	UTSW	14	26,445,766 (GRCm39)	missense	probably benign
R7426:Dnah12	UTSW	14	26,445,781 (GRCm39)	missense	probably benign	0.01
R7472:Dnah12	UTSW	14	26,578,592 (GRCm39)	missense	probably benign	0.01
R7579:Dnah12	UTSW	14	26,492,460 (GRCm39)	missense	probably benign	0.05
R7655:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7656:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7694:Dnah12	UTSW	14	26,503,337 (GRCm39)	missense	probably damaging	1.00
R7730:Dnah12	UTSW	14	26,507,890 (GRCm39)	missense	probably damaging	1.00
R7837:Dnah12	UTSW	14	26,518,176 (GRCm39)	missense	probably benign	0.01
R7855:Dnah12	UTSW	14	26,551,286 (GRCm39)	missense	probably benign	0.14
R7870:Dnah12	UTSW	14	26,578,486 (GRCm39)	missense	probably benign	0.00
R7920:Dnah12	UTSW	14	26,578,499 (GRCm39)	missense	possibly damaging	0.58
R7933:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
R7956:Dnah12	UTSW	14	26,430,427 (GRCm39)	missense	probably damaging	0.96
R8192:Dnah12	UTSW	14	26,428,036 (GRCm39)	missense	probably benign
R8263:Dnah12	UTSW	14	26,613,421 (GRCm39)	missense	noncoding transcript
R8287:Dnah12	UTSW	14	26,534,560 (GRCm39)	missense	probably benign
R8336:Dnah12	UTSW	14	26,432,220 (GRCm39)	missense	probably benign	0.01
R8362:Dnah12	UTSW	14	26,576,788 (GRCm39)	missense	probably damaging	1.00
R8392:Dnah12	UTSW	14	26,607,869 (GRCm39)	missense	probably benign
R8458:Dnah12	UTSW	14	26,548,849 (GRCm39)	critical splice acceptor site	probably null
R8481:Dnah12	UTSW	14	26,575,753 (GRCm39)	missense	probably benign	0.02
R8551:Dnah12	UTSW	14	26,496,227 (GRCm39)	missense	probably damaging	0.97
R8669:Dnah12	UTSW	14	26,552,582 (GRCm39)	splice site	probably benign
R8698:Dnah12	UTSW	14	26,428,418 (GRCm39)	missense	probably benign	0.02
R8709:Dnah12	UTSW	14	26,414,757 (GRCm39)	missense	probably benign	0.00
R8778:Dnah12	UTSW	14	26,455,718 (GRCm39)	missense	probably benign	0.29
R9049:Dnah12	UTSW	14	26,443,275 (GRCm39)	missense	probably benign	0.00
R9087:Dnah12	UTSW	14	26,546,503 (GRCm39)	missense	probably damaging	1.00
R9099:Dnah12	UTSW	14	26,492,325 (GRCm39)	missense	probably benign	0.31
R9153:Dnah12	UTSW	14	26,536,569 (GRCm39)	missense	probably damaging	1.00
R9177:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9214:Dnah12	UTSW	14	26,445,060 (GRCm39)	missense	probably benign	0.02
R9268:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9274:Dnah12	UTSW	14	26,537,374 (GRCm39)	missense	probably benign	0.00
R9293:Dnah12	UTSW	14	26,495,016 (GRCm39)	missense	probably benign
R9322:Dnah12	UTSW	14	26,492,934 (GRCm39)	missense	possibly damaging	0.75
R9353:Dnah12	UTSW	14	26,578,507 (GRCm39)	missense	probably damaging	1.00
R9506:Dnah12	UTSW	14	26,514,168 (GRCm39)	missense	probably benign	0.00
R9518:Dnah12	UTSW	14	26,495,713 (GRCm39)	missense	probably damaging	1.00
R9524:Dnah12	UTSW	14	26,572,494 (GRCm39)	missense	probably null	0.91
R9562:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9565:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9573:Dnah12	UTSW	14	26,414,619 (GRCm39)	missense	probably benign
R9581:Dnah12	UTSW	14	26,491,985 (GRCm39)	missense	probably damaging	1.00
R9689:Dnah12	UTSW	14	26,590,871 (GRCm39)	missense	probably null	1.00
R9727:Dnah12	UTSW	14	26,523,510 (GRCm39)	nonsense	probably null
V7580:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
V7581:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
X0018:Dnah12	UTSW	14	26,536,437 (GRCm39)	missense	probably damaging	1.00
X0027:Dnah12	UTSW	14	26,538,245 (GRCm39)	missense	probably damaging	1.00
X0065:Dnah12	UTSW	14	26,536,602 (GRCm39)	missense	possibly damaging	0.93
Z1177:Dnah12	UTSW	14	26,597,172 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGTACTCCATGCTACATTTCCAAAG -3'
(R):5'- ACTGGAGCATTCCCATTCC -3'

Sequencing Primer
(F):5'- CCATGCTACATTTCCAAAGTGATAG -3'
(R):5'- TTCCCATTCCGCAGATGATGAAAG -3'

Posted On

2015-07-07