Mutagenetix > Incidental Mutation

Incidental Mutation 'R4467:Gm9978'

329247

Institutional Source

Beutler Lab

Gene Symbol

Gm9978

Ensembl Gene

ENSMUSG00000055704

Gene Name

predicted gene 9978

Synonyms

MMRRC Submission

041724-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

R4467 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

78320404-78323676 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to A at 78322750 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000069431

SMART Domains

Protein: ENSMUSP00000070442
Gene: ENSMUSG00000055704

Domain	Start	End	E-Value	Type
low complexity region	34	46	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000219248

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000220136

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 97.1%
20x: 95.0%

Validation Efficiency

98% (52/53)

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610040J01Rik	G	T	5: 64,056,182 (GRCm39)		probably benign	Het
Atg4a-ps	A	G	3: 103,553,171 (GRCm39)	Y57H	probably damaging	Het
Bag4	C	T	8: 26,259,516 (GRCm39)	A228T	probably benign	Het
Bms1	G	A	6: 118,360,808 (GRCm39)	T1220I	probably damaging	Het
Brat1	T	C	5: 140,690,826 (GRCm39)		probably benign	Het
Cds2	T	A	2: 132,136,366 (GRCm39)	Y39*	probably null	Het
Chrnd	T	A	1: 87,125,099 (GRCm39)	L384Q	probably damaging	Het
Cpa3	A	T	3: 20,282,981 (GRCm39)	Y155*	probably null	Het
Crlf1	G	A	8: 70,953,606 (GRCm39)	W260*	probably null	Het
Cux1	C	G	5: 136,341,576 (GRCm39)	E605D	probably damaging	Het
Cylc2	C	G	4: 51,229,651 (GRCm39)	T331R	unknown	Het
Dmtf1	T	C	5: 9,186,085 (GRCm39)	N167S	probably damaging	Het
Dnaaf9	A	G	2: 130,609,567 (GRCm39)	I372T	probably damaging	Het
Dnai7	A	T	6: 145,128,944 (GRCm39)		probably null	Het
Dtx2	T	A	5: 136,040,930 (GRCm39)	W112R	probably damaging	Het
Elf3	A	G	1: 135,184,582 (GRCm39)	I138T	probably damaging	Het
F11	T	A	8: 45,694,511 (GRCm39)	I617F	probably damaging	Het
Fdps	A	T	3: 89,008,093 (GRCm39)	D8E	possibly damaging	Het
Fzd10	C	A	5: 128,678,340 (GRCm39)	T20K	probably benign	Het
Gpr158	T	A	2: 21,831,810 (GRCm39)	M970K	probably damaging	Het
Has1	C	T	17: 18,064,257 (GRCm39)	V461M	probably benign	Het
Hdac3	C	T	18: 38,085,566 (GRCm39)	G80D	probably benign	Het
Klk12	A	T	7: 43,422,807 (GRCm39)	R245W	probably damaging	Het
Lamp5	A	G	2: 135,900,940 (GRCm39)	I47V	probably damaging	Het
Or6c1b	T	C	10: 129,272,933 (GRCm39)	I84T	probably benign	Het
Ovgp1	A	G	3: 105,885,027 (GRCm39)	D122G	probably benign	Het
Piezo1	T	C	8: 123,213,135 (GRCm39)	E1875G	probably benign	Het
Pih1d1	A	G	7: 44,807,921 (GRCm39)	M132V	possibly damaging	Het
Pon2	C	T	6: 5,267,021 (GRCm39)	A241T	probably benign	Het
Prkce	A	G	17: 86,927,339 (GRCm39)	I538V	possibly damaging	Het
Rab36	C	T	10: 74,887,875 (GRCm39)	R249*	probably null	Het
Rps6kl1	C	T	12: 85,194,582 (GRCm39)	A110T	probably damaging	Het
Rsad1	T	C	11: 94,435,356 (GRCm39)	T244A	probably benign	Het
Slc22a7	T	C	17: 46,743,436 (GRCm39)	I532V	probably benign	Het
Slc2a7	T	C	4: 150,247,731 (GRCm39)	V377A	possibly damaging	Het
Slx4	A	G	16: 3,806,919 (GRCm39)	V508A	possibly damaging	Het
Stag2	A	G	X: 41,322,749 (GRCm39)	S400G	probably benign	Het
Stat6	T	G	10: 127,487,097 (GRCm39)	I201M	probably damaging	Het
Stim2	T	C	5: 54,273,536 (GRCm39)		probably null	Het
Tbc1d9	A	G	8: 83,937,107 (GRCm39)	Y63C	probably damaging	Het
Tctn2	T	C	5: 124,758,252 (GRCm39)		noncoding transcript	Het
Tmem181a	T	A	17: 6,346,061 (GRCm39)	L185H	probably damaging	Het
Ubr5	T	A	15: 38,004,580 (GRCm39)	T1282S	probably damaging	Het
Ufl1	A	T	4: 25,254,806 (GRCm39)	I550N	probably damaging	Het
Uty	A	G	Y: 1,158,372 (GRCm39)	V557A	possibly damaging	Het
Vmn1r54	T	C	6: 90,246,253 (GRCm39)	S56P	probably damaging	Het
Zfp980	G	A	4: 145,428,653 (GRCm39)	G461S	probably benign	Het

Other mutations in Gm9978

Allele	Source	Chr	Coord	Type	Predicted Effect
R2117:Gm9978	UTSW	10	78,322,731 (GRCm39)	unclassified	noncoding transcript
R5937:Gm9978	UTSW	10	78,322,675 (GRCm39)	unclassified	noncoding transcript
R6018:Gm9978	UTSW	10	78,322,915 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- TAAAGCACAGCTGGGTCAG -3'
(R):5'- CACAGTGACAGGTGAAGGTC -3'

Sequencing Primer
(F):5'- ACAGCTGGGTCAGGTCAG -3'
(R):5'- ACAGCACTGGCCTCCATG -3'

Posted On

2015-07-21