Mutagenetix > Incidental Mutation

Incidental Mutation 'R4458:Fsip2'

329987

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

041718-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.123) question?

Stock #

R4458 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

82773978-82839281 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 82821120 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Serine at position 5618 (A5618S)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000143764
AA Change: A5618S

PolyPhen 2 Score 0.705 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: A5618S

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Meta Mutation Damage Score

0.1795

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 95.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A630076J17Rik	G	A	3: 107,139,997 (GRCm39)		probably null	Het
Akap13	A	G	7: 75,389,213 (GRCm39)	D2377G	probably damaging	Het
Ankrd44	A	T	1: 54,801,550 (GRCm39)	I56N	possibly damaging	Het
Apob	T	A	12: 8,065,445 (GRCm39)	I4105N	probably damaging	Het
Arhgap5	T	A	12: 52,564,740 (GRCm39)	N570K	probably benign	Het
Arid1b	A	T	17: 5,293,191 (GRCm39)	Q703L	probably damaging	Het
Atp4a	G	A	7: 30,419,650 (GRCm39)	R671Q	probably benign	Het
Cad	T	A	5: 31,218,570 (GRCm39)	V499D	probably damaging	Het
Cdkn2d	C	G	9: 21,202,185 (GRCm39)	V21L	probably benign	Het
Celsr2	A	C	3: 108,302,313 (GRCm39)	I2605S	probably damaging	Het
Chd6	T	A	2: 160,871,796 (GRCm39)	Y213F	possibly damaging	Het
Clec18a	T	A	8: 111,802,102 (GRCm39)	T296S	probably damaging	Het
Crybg2	C	T	4: 133,802,205 (GRCm39)	P1122S	probably benign	Het
Cyld	G	T	8: 89,445,929 (GRCm39)	S309I	probably benign	Het
Dctn5	G	T	7: 121,734,303 (GRCm39)	R49L	probably damaging	Het
Egr2	GAA	GA	10: 67,375,733 (GRCm39)		probably null	Het
Erbin	C	A	13: 103,970,065 (GRCm39)	V1184F	probably damaging	Het
Ercc2	G	T	7: 19,127,771 (GRCm39)	R406L	probably damaging	Het
Eya1	C	T	1: 14,253,420 (GRCm39)	V519M	probably damaging	Het
Flad1	T	C	3: 89,316,241 (GRCm39)	H107R	probably benign	Het
Gabbr1	G	T	17: 37,378,667 (GRCm39)		probably null	Het
Haghl	A	T	17: 26,003,994 (GRCm39)	V30E	probably damaging	Het
Itga5	C	T	15: 103,258,630 (GRCm39)	E822K	probably damaging	Het
Klhl26	T	A	8: 70,905,342 (GRCm39)	E108D	possibly damaging	Het
Kpnb1	A	T	11: 97,059,996 (GRCm39)	L558Q	probably damaging	Het
Lias	T	C	5: 65,551,383 (GRCm39)		probably null	Het
Ltbp1	A	T	17: 75,583,502 (GRCm39)	K434M	possibly damaging	Het
Marchf1	C	A	8: 66,908,823 (GRCm39)	A177E	probably damaging	Het
Naip2	T	A	13: 100,291,419 (GRCm39)	H1173L	probably benign	Het
Nol4	T	C	18: 22,885,052 (GRCm39)	I419V	probably damaging	Het
Nol6	A	G	4: 41,115,888 (GRCm39)	L1068P	probably damaging	Het
Nrcam	T	C	12: 44,606,513 (GRCm39)	S420P	probably damaging	Het
Or10c1	A	T	17: 37,522,204 (GRCm39)	I180N	possibly damaging	Het
Pitpnm2	T	C	5: 124,259,439 (GRCm39)	T1299A	probably benign	Het
Prdm16	A	G	4: 154,406,765 (GRCm39)	V1220A	probably benign	Het
Saraf	T	C	8: 34,621,870 (GRCm39)	S25P	unknown	Het
Serpine3	C	A	14: 62,911,922 (GRCm39)	L295I	probably damaging	Het
Sntb2	G	A	8: 107,718,239 (GRCm39)		probably null	Het
Surf6	T	C	2: 26,782,721 (GRCm39)	E202G	probably benign	Het
Tent5a	T	C	9: 85,208,527 (GRCm39)	I99V	possibly damaging	Het
Th	A	T	7: 142,450,690 (GRCm39)	D135E	probably benign	Het
Traf1	A	G	2: 34,835,445 (GRCm39)	Y326H	probably damaging	Het
Tshz2	G	A	2: 169,727,008 (GRCm39)	A66T	probably benign	Het
Ttn	T	C	2: 76,777,257 (GRCm39)	M1382V	probably benign	Het
Ubqlnl	A	G	7: 103,798,396 (GRCm39)	V367A	probably benign	Het
Uspl1	T	A	5: 149,150,962 (GRCm39)	S707T	possibly damaging	Het
Utp18	A	G	11: 93,761,359 (GRCm39)	S350P	possibly damaging	Het
Vmn1r177	A	G	7: 23,565,645 (GRCm39)	V77A	possibly damaging	Het
Vmn1r229	A	G	17: 21,034,894 (GRCm39)	I46M	probably damaging	Het
Vnn3	T	C	10: 23,741,567 (GRCm39)	Y291H	probably benign	Het
Vps9d1	A	G	8: 123,974,487 (GRCm39)	S267P	probably benign	Het
Wrn	T	A	8: 33,785,026 (GRCm39)	T692S	probably damaging	Het
Yeats2	T	C	16: 20,032,071 (GRCm39)	I19T	probably damaging	Het
Zfp13	G	A	17: 23,800,150 (GRCm39)	A36V	probably benign	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,820,730 (GRCm39)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,821,657 (GRCm39)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,830,163 (GRCm39)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,823,326 (GRCm39)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,807,863 (GRCm39)	missense	probably benign
IGL01554:Fsip2	APN	2	82,807,622 (GRCm39)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,821,430 (GRCm39)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,808,691 (GRCm39)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,812,983 (GRCm39)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,815,273 (GRCm39)	missense	probably benign
IGL01918:Fsip2	APN	2	82,822,482 (GRCm39)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,824,349 (GRCm39)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,824,211 (GRCm39)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,822,204 (GRCm39)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,809,065 (GRCm39)	missense	probably benign
IGL02155:Fsip2	APN	2	82,828,696 (GRCm39)	missense	probably benign
IGL02219:Fsip2	APN	2	82,808,174 (GRCm39)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,813,116 (GRCm39)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,809,137 (GRCm39)	missense	probably benign
IGL02478:Fsip2	APN	2	82,814,736 (GRCm39)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,809,199 (GRCm39)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,822,347 (GRCm39)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,779,836 (GRCm39)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,823,407 (GRCm39)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,828,662 (GRCm39)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,812,501 (GRCm39)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,781,370 (GRCm39)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,823,839 (GRCm39)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,822,701 (GRCm39)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,813,398 (GRCm39)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,820,968 (GRCm39)	intron	probably benign
IGL03076:Fsip2	APN	2	82,812,482 (GRCm39)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,808,420 (GRCm39)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,807,737 (GRCm39)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,820,814 (GRCm39)	missense	probably benign
bubblegum	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
Dao	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
engulf	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
envelope	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
gladius	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
glove	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
Katana	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
scarf	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
Sock	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
swaddle	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
wrap	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
Wrapper	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,818,756 (GRCm39)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,814,709 (GRCm39)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,814,706 (GRCm39)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,821,196 (GRCm39)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,830,201 (GRCm39)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,806,952 (GRCm39)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,815,269 (GRCm39)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,821,465 (GRCm39)	missense	probably benign
R0149:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,811,151 (GRCm39)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,815,521 (GRCm39)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,816,240 (GRCm39)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,813,677 (GRCm39)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,814,908 (GRCm39)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,821,419 (GRCm39)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,808,129 (GRCm39)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,777,296 (GRCm39)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,824,139 (GRCm39)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,807,877 (GRCm39)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,774,484 (GRCm39)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,819,302 (GRCm39)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,807,241 (GRCm39)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,816,513 (GRCm39)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,821,703 (GRCm39)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,812,683 (GRCm39)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,816,617 (GRCm39)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,815,828 (GRCm39)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,828,375 (GRCm39)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,819,780 (GRCm39)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,818,805 (GRCm39)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,805,378 (GRCm39)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,821,844 (GRCm39)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,805,570 (GRCm39)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,805,361 (GRCm39)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,811,355 (GRCm39)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,820,107 (GRCm39)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,819,752 (GRCm39)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,820,089 (GRCm39)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,828,407 (GRCm39)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,817,539 (GRCm39)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,810,155 (GRCm39)	missense	probably benign
R1520:Fsip2	UTSW	2	82,811,058 (GRCm39)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,811,931 (GRCm39)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,816,626 (GRCm39)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,808,861 (GRCm39)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,816,689 (GRCm39)	missense	probably benign
R1700:Fsip2	UTSW	2	82,822,081 (GRCm39)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,805,289 (GRCm39)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,820,256 (GRCm39)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,818,055 (GRCm39)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,815,240 (GRCm39)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,830,185 (GRCm39)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,807,906 (GRCm39)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,814,933 (GRCm39)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,823,601 (GRCm39)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,811,127 (GRCm39)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,817,077 (GRCm39)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,810,902 (GRCm39)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,821,894 (GRCm39)	missense	probably benign
R1965:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,810,175 (GRCm39)	missense	probably benign
R1988:Fsip2	UTSW	2	82,806,861 (GRCm39)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,819,788 (GRCm39)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,808,856 (GRCm39)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,806,699 (GRCm39)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	82,839,159 (GRCm39)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,818,923 (GRCm39)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,820,615 (GRCm39)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,807,823 (GRCm39)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,793,095 (GRCm39)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,805,437 (GRCm39)	missense	probably benign
R2344:Fsip2	UTSW	2	82,820,257 (GRCm39)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,806,593 (GRCm39)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,811,064 (GRCm39)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,815,685 (GRCm39)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,809,954 (GRCm39)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,782,001 (GRCm39)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,808,511 (GRCm39)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,820,775 (GRCm39)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,809,389 (GRCm39)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,821,868 (GRCm39)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,816,854 (GRCm39)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,822,354 (GRCm39)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,817,071 (GRCm39)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,815,253 (GRCm39)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,819,311 (GRCm39)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,808,561 (GRCm39)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,813,058 (GRCm39)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,781,290 (GRCm39)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,819,950 (GRCm39)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,816,759 (GRCm39)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,789,006 (GRCm39)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,813,862 (GRCm39)	missense	probably benign
R4042:Fsip2	UTSW	2	82,813,896 (GRCm39)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,813,245 (GRCm39)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,817,413 (GRCm39)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,808,201 (GRCm39)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,821,550 (GRCm39)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,782,009 (GRCm39)	missense	probably benign
R4549:Fsip2	UTSW	2	82,819,972 (GRCm39)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,815,297 (GRCm39)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,816,510 (GRCm39)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,809,017 (GRCm39)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,818,103 (GRCm39)	missense	probably benign
R4700:Fsip2	UTSW	2	82,817,373 (GRCm39)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,805,203 (GRCm39)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,805,697 (GRCm39)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,819,629 (GRCm39)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,812,452 (GRCm39)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,818,044 (GRCm39)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,818,786 (GRCm39)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,820,515 (GRCm39)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,815,815 (GRCm39)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,779,739 (GRCm39)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,821,295 (GRCm39)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,805,202 (GRCm39)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,818,438 (GRCm39)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,811,837 (GRCm39)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,824,114 (GRCm39)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,815,384 (GRCm39)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,807,758 (GRCm39)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,777,276 (GRCm39)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,816,222 (GRCm39)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,809,773 (GRCm39)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,819,477 (GRCm39)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,818,836 (GRCm39)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,821,460 (GRCm39)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,822,329 (GRCm39)	missense	probably benign
R5119:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,811,768 (GRCm39)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,808,916 (GRCm39)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,813,338 (GRCm39)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,823,505 (GRCm39)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,808,925 (GRCm39)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,818,489 (GRCm39)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,820,185 (GRCm39)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,805,742 (GRCm39)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,821,262 (GRCm39)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,812,572 (GRCm39)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,810,230 (GRCm39)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,815,654 (GRCm39)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,815,542 (GRCm39)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,781,256 (GRCm39)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,781,252 (GRCm39)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,793,090 (GRCm39)	missense	probably benign
R5568:Fsip2	UTSW	2	82,816,908 (GRCm39)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,828,472 (GRCm39)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,818,439 (GRCm39)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,817,838 (GRCm39)	nonsense	probably null
R5712:Fsip2	UTSW	2	82,839,192 (GRCm39)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,808,260 (GRCm39)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,815,084 (GRCm39)	missense	probably benign
R5881:Fsip2	UTSW	2	82,814,785 (GRCm39)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,822,953 (GRCm39)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,818,852 (GRCm39)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,817,092 (GRCm39)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,807,835 (GRCm39)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,793,657 (GRCm39)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,820,812 (GRCm39)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,818,283 (GRCm39)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,822,471 (GRCm39)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,816,017 (GRCm39)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,809,777 (GRCm39)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,821,388 (GRCm39)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,824,112 (GRCm39)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,818,289 (GRCm39)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,817,601 (GRCm39)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,811,071 (GRCm39)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,812,798 (GRCm39)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,820,227 (GRCm39)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,810,785 (GRCm39)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,819,242 (GRCm39)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,823,416 (GRCm39)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,823,028 (GRCm39)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,813,836 (GRCm39)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,812,657 (GRCm39)	missense	probably benign
R6621:Fsip2	UTSW	2	82,820,158 (GRCm39)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,813,571 (GRCm39)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,798,161 (GRCm39)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,809,878 (GRCm39)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,816,776 (GRCm39)	missense	probably benign
R6790:Fsip2	UTSW	2	82,821,283 (GRCm39)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,811,303 (GRCm39)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,815,544 (GRCm39)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,813,969 (GRCm39)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,816,332 (GRCm39)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,809,061 (GRCm39)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,778,630 (GRCm39)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,807,298 (GRCm39)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,817,269 (GRCm39)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,820,979 (GRCm39)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,821,235 (GRCm39)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,811,078 (GRCm39)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,813,496 (GRCm39)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,817,968 (GRCm39)	missense	probably benign
R7126:Fsip2	UTSW	2	82,813,485 (GRCm39)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,813,085 (GRCm39)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,811,541 (GRCm39)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,816,571 (GRCm39)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,823,581 (GRCm39)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,819,412 (GRCm39)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,814,015 (GRCm39)	missense	probably benign
R7228:Fsip2	UTSW	2	82,822,651 (GRCm39)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,812,484 (GRCm39)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,823,607 (GRCm39)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,809,425 (GRCm39)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,812,474 (GRCm39)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,810,863 (GRCm39)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,820,035 (GRCm39)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,813,462 (GRCm39)	missense	probably benign
R7343:Fsip2	UTSW	2	82,809,711 (GRCm39)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,819,140 (GRCm39)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,820,663 (GRCm39)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,815,601 (GRCm39)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,810,441 (GRCm39)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,782,024 (GRCm39)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,818,894 (GRCm39)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,815,196 (GRCm39)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,824,337 (GRCm39)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,819,361 (GRCm39)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,805,585 (GRCm39)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,817,256 (GRCm39)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,812,149 (GRCm39)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,820,455 (GRCm39)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,811,252 (GRCm39)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,818,723 (GRCm39)	missense	probably benign
R7811:Fsip2	UTSW	2	82,828,797 (GRCm39)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,807,044 (GRCm39)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,808,168 (GRCm39)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,781,365 (GRCm39)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,816,120 (GRCm39)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,818,793 (GRCm39)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
R8034:Fsip2	UTSW	2	82,819,699 (GRCm39)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,816,322 (GRCm39)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,789,017 (GRCm39)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,823,296 (GRCm39)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,806,141 (GRCm39)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,818,021 (GRCm39)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,815,088 (GRCm39)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,806,951 (GRCm39)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,820,808 (GRCm39)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,808,487 (GRCm39)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,811,346 (GRCm39)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,818,724 (GRCm39)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,821,099 (GRCm39)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,818,198 (GRCm39)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,822,239 (GRCm39)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8419:Fsip2	UTSW	2	82,808,963 (GRCm39)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,811,910 (GRCm39)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,807,430 (GRCm39)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8459:Fsip2	UTSW	2	82,810,022 (GRCm39)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,810,284 (GRCm39)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,777,336 (GRCm39)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,821,871 (GRCm39)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,815,246 (GRCm39)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,811,453 (GRCm39)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,815,822 (GRCm39)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,813,453 (GRCm39)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,821,606 (GRCm39)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,820,782 (GRCm39)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,809,524 (GRCm39)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,807,681 (GRCm39)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,816,984 (GRCm39)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,810,938 (GRCm39)	missense	probably benign
R8926:Fsip2	UTSW	2	82,823,927 (GRCm39)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,815,370 (GRCm39)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,806,898 (GRCm39)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,817,075 (GRCm39)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,828,545 (GRCm39)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,806,180 (GRCm39)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,807,301 (GRCm39)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,816,103 (GRCm39)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,813,170 (GRCm39)	missense	probably benign
R9149:Fsip2	UTSW	2	82,812,374 (GRCm39)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,815,574 (GRCm39)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,817,844 (GRCm39)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,820,425 (GRCm39)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,823,062 (GRCm39)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,815,958 (GRCm39)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,807,662 (GRCm39)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,818,604 (GRCm39)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,818,747 (GRCm39)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,811,039 (GRCm39)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,822,756 (GRCm39)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,819,793 (GRCm39)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,805,907 (GRCm39)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,816,702 (GRCm39)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,806,132 (GRCm39)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,817,285 (GRCm39)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,793,062 (GRCm39)	missense	probably benign
R9523:Fsip2	UTSW	2	82,807,972 (GRCm39)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,798,173 (GRCm39)	missense	probably benign
R9636:Fsip2	UTSW	2	82,820,563 (GRCm39)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,821,984 (GRCm39)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,819,272 (GRCm39)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,806,226 (GRCm39)	missense	probably benign
R9705:Fsip2	UTSW	2	82,823,634 (GRCm39)	missense	probably benign
R9739:Fsip2	UTSW	2	82,823,896 (GRCm39)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,818,241 (GRCm39)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,821,994 (GRCm39)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,810,225 (GRCm39)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,821,865 (GRCm39)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,822,876 (GRCm39)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,808,184 (GRCm39)	missense	probably benign
RF028:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,812,851 (GRCm39)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,781,364 (GRCm39)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,785,290 (GRCm39)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,807,122 (GRCm39)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,817,807 (GRCm39)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,818,978 (GRCm39)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,817,997 (GRCm39)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,805,792 (GRCm39)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,820,009 (GRCm39)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,814,868 (GRCm39)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,777,304 (GRCm39)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,817,547 (GRCm39)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- ACAGTCAGTGATGTCTCCACC -3'
(R):5'- GAATCTGCCCCTGCTCATTG -3'

Sequencing Primer
(F):5'- GTGATGTCTCCACCCACCAC -3'
(R):5'- CCTGCTCATTGACTAGGACTAAG -3'

Posted On

2015-07-21