Mutagenetix > Incidental Mutation

Incidental Mutation 'R4509:Gm15032'

331146

Institutional Source

Beutler Lab

Gene Symbol

Gm15032

Ensembl Gene

ENSMUSG00000081568

Gene Name

predicted gene 15032

Synonyms

MMRRC Submission

041758-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

R4509 (G1)

Quality Score

222

Status

Validated

Chromosome

Chromosomal Location

141405488-141405898 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

A to T at 141405622 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000118547

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.5%
20x: 95.8%

Validation Efficiency

98% (48/49)

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8b	A	G	11: 109,857,581 (GRCm39)	L657P	probably damaging	Het
Adam4	A	T	12: 81,468,521 (GRCm39)	C33*	probably null	Het
Adam6b	T	C	12: 113,453,972 (GRCm39)	V263A	probably benign	Het
Arid1a	A	C	4: 133,423,010 (GRCm39)		probably benign	Het
Ascc3	T	C	10: 50,718,339 (GRCm39)	F2011L	probably benign	Het
Atp5pf	T	C	16: 84,624,862 (GRCm39)	D104G	probably benign	Het
Cacna1d	T	C	14: 29,818,928 (GRCm39)	Y1209C	probably damaging	Het
Camta2	G	A	11: 70,571,844 (GRCm39)	T484M	probably benign	Het
Ccdc178	T	C	18: 22,200,449 (GRCm39)	N452D	possibly damaging	Het
Col1a2	G	A	6: 4,518,822 (GRCm39)		probably benign	Het
Cttnbp2nl	T	C	3: 104,940,063 (GRCm39)	N2S	probably damaging	Het
Gzmg	G	A	14: 56,394,210 (GRCm39)	P228L	probably damaging	Het
Hao1	T	A	2: 134,364,964 (GRCm39)	D221V	probably damaging	Het
Ints9	A	G	14: 65,266,381 (GRCm39)	D411G	possibly damaging	Het
Lnx1	C	T	5: 74,780,853 (GRCm39)	D382N	probably damaging	Het
Mdn1	C	T	4: 32,715,883 (GRCm39)	R2022C	probably damaging	Het
Mipep	T	C	14: 61,064,770 (GRCm39)	Y375H	probably damaging	Het
Muc6	G	A	7: 141,218,313 (GRCm39)	S2120F	possibly damaging	Het
Pah	T	C	10: 87,412,077 (GRCm39)		probably null	Het
Perm1	T	C	4: 156,302,043 (GRCm39)	S196P	probably benign	Het
Pik3c2g	A	T	6: 139,665,732 (GRCm39)	T18S	probably benign	Het
Polq	G	A	16: 36,868,925 (GRCm39)	R765H	probably damaging	Het
Ppp3cb	A	T	14: 20,565,569 (GRCm39)		probably benign	Het
Psd4	T	C	2: 24,286,347 (GRCm39)	S316P	probably benign	Het
Ptpn18	T	C	1: 34,501,823 (GRCm39)	V45A	possibly damaging	Het
Rasgrp3	A	G	17: 75,807,668 (GRCm39)	M242V	probably damaging	Het
Repin1	T	C	6: 48,573,460 (GRCm39)	C130R	possibly damaging	Het
Rrp1	G	T	10: 78,248,656 (GRCm39)	T44K	possibly damaging	Het
Slc44a5	A	G	3: 153,939,710 (GRCm39)	Y88C	probably damaging	Het
Socs1	C	T	16: 10,602,218 (GRCm39)	R173Q	probably benign	Het
Speer3	T	G	5: 13,846,368 (GRCm39)	N229K	possibly damaging	Het
Sult2a7	T	A	7: 14,204,086 (GRCm39)	I226F	probably damaging	Het
Tdp1	G	A	12: 99,921,324 (GRCm39)		probably benign	Het
Tnfrsf21	G	A	17: 43,396,279 (GRCm39)	S521N	probably benign	Het
Tnip1	T	A	11: 54,817,616 (GRCm39)	S244C	probably benign	Het
Ubqln3	G	A	7: 103,790,651 (GRCm39)	L480F	probably damaging	Het
Vps13d	G	A	4: 144,789,172 (GRCm39)	P3817L	probably damaging	Het
Xpr1	A	G	1: 155,165,907 (GRCm39)		probably benign	Het
Zfhx3	A	G	8: 109,520,411 (GRCm39)	E511G	probably benign	Het
Zfp560	C	T	9: 20,260,019 (GRCm39)	C281Y	probably damaging	Het

Predicted Primers

PCR Primer
(F):5'- TCAGGCATGGAATGGTGGAC -3'
(R):5'- TCTCTGTGAAGGGAATCAAGGTAC -3'

Sequencing Primer
(F):5'- GGAATGGTGGACTTTCCTAAGACATC -3'
(R):5'- TCAAGGTACGGCTGAACAGACTTC -3'

Posted On

2015-07-21