Mutagenetix > Incidental Mutation

Incidental Mutation 'R4501:Dnah2'

331822

Institutional Source

Beutler Lab

Gene Symbol

Dnah2

Ensembl Gene

ENSMUSG00000005237

Gene Name

dynein, axonemal, heavy chain 2

Synonyms

2900022L05Rik, D330014H01Rik, Dnahc2, Dnhd3

MMRRC Submission

041753-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4501 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

69311635-69439934 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 69368485 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Leucine at position 1717 (M1717L)

Ref Sequence

ENSEMBL: ENSMUSP00000104299 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035539] [ENSMUST00000108659]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000035539

SMART Domains

Protein: ENSMUSP00000047329
Gene: ENSMUSG00000005237

Domain	Start	End	E-Value	Type
low complexity region	4	25	N/A	INTRINSIC
Pfam:DHC_N1	273	429	6.6e-37	PFAM
Pfam:DHC_N1	432	761	1.3e-54	PFAM
Pfam:DHC_N2	1253	1668	3.4e-144	PFAM
AAA	1826	1962	2.95e-1	SMART
Pfam:AAA_5	2108	2251	1.3e-5	PFAM
AAA	2437	2584	3.63e-5	SMART
Pfam:AAA_8	2752	3022	1.1e-75	PFAM
Pfam:MT	3034	3370	8.7e-55	PFAM
Pfam:AAA_9	3386	3616	7.4e-68	PFAM
Pfam:Dynein_heavy	3748	4453	1.2e-220	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000108659
AA Change: M1717L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000104299
Gene: ENSMUSG00000005237
AA Change: M1717L

Domain	Start	End	E-Value	Type
low complexity region	4	25	N/A	INTRINSIC
Pfam:DHC_N1	274	429	1.1e-47	PFAM
Pfam:DHC_N1	438	760	1.5e-75	PFAM
Pfam:DHC_N2	1255	1666	4.4e-144	PFAM
low complexity region	1711	1720	N/A	INTRINSIC
AAA	1832	1968	2.95e-1	SMART
Blast:AAA	2111	2251	2e-86	BLAST
AAA	2443	2590	3.63e-5	SMART
Pfam:AAA_8	2758	3028	5.5e-77	PFAM
Pfam:MT	3040	3376	7.6e-55	PFAM
Pfam:AAA_9	3396	3621	7.5e-94	PFAM
Pfam:Dynein_heavy	3759	4458	4.9e-264	PFAM

Meta Mutation Damage Score

0.0582

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 95.0%

Validation Efficiency

100% (37/37)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acin1	A	G	14: 54,924,044 (GRCm39)	V65A	probably damaging	Het
Ankrd28	A	G	14: 31,428,753 (GRCm39)	L956S	probably damaging	Het
Atp2a1	G	A	7: 126,052,555 (GRCm39)	T388I	probably benign	Het
AU018091	A	G	7: 3,208,919 (GRCm39)	V389A	probably benign	Het
Cdh2	A	G	18: 16,762,642 (GRCm39)	V434A	possibly damaging	Het
Dennd4a	G	A	9: 64,817,405 (GRCm39)	D1680N	possibly damaging	Het
Dusp6	T	A	10: 99,100,457 (GRCm39)	L151Q	probably benign	Het
Hc	A	T	2: 34,887,488 (GRCm39)		probably null	Het
Hmcn1	A	T	1: 150,509,417 (GRCm39)	S3644T	probably damaging	Het
Kcnt2	T	C	1: 140,480,718 (GRCm39)	I761T	probably damaging	Het
Mmd2	A	G	5: 142,560,965 (GRCm39)	V90A	probably benign	Het
Ncf2	C	G	1: 152,710,784 (GRCm39)	Q432E	probably benign	Het
Nxn	T	C	11: 76,165,438 (GRCm39)	E172G	probably damaging	Het
P2ry12	A	G	3: 59,125,078 (GRCm39)	I199T	probably damaging	Het
Phldb3	A	G	7: 24,311,986 (GRCm39)	E100G	probably benign	Het
Pidd1	A	G	7: 141,021,356 (GRCm39)		probably benign	Het
Pldi	G	T	10: 60,764,188 (GRCm39)		noncoding transcript	Het
Plk5	T	C	10: 80,195,305 (GRCm39)	C208R	probably benign	Het
Ptpn12	G	T	5: 21,224,278 (GRCm39)	A105E	probably damaging	Het
Pusl1	T	C	4: 155,973,999 (GRCm39)	T252A	probably benign	Het
Rpl13a	T	C	7: 44,775,564 (GRCm39)	H95R	probably benign	Het
Sh3d21	GAATCTCCTGGGAAAATC	GAATC	4: 126,056,652 (GRCm39)		probably null	Het
Slc30a4	A	G	2: 122,527,136 (GRCm39)	I370T	probably benign	Het
Taf1c	A	G	8: 120,326,168 (GRCm39)	F565L	probably damaging	Het
Tdrd9	A	G	12: 112,009,243 (GRCm39)	K1050E	probably benign	Het
Tnrc6c	T	A	11: 117,613,324 (GRCm39)	L494Q	probably damaging	Het
Ttn	T	A	2: 76,624,991 (GRCm39)	I13450L	possibly damaging	Het
Usp34	C	A	11: 23,351,529 (GRCm39)	P1439Q	probably damaging	Het
Usp5	C	G	6: 124,799,593 (GRCm39)	K318N	possibly damaging	Het
Vmn1r80	A	G	7: 11,927,318 (GRCm39)	N143D	probably benign	Het
Zbtb44	G	A	9: 30,965,462 (GRCm39)	V291I	probably damaging	Het

Other mutations in Dnah2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00087:Dnah2	APN	11	69,383,498 (GRCm39)	missense	possibly damaging	0.93
IGL00418:Dnah2	APN	11	69,385,892 (GRCm39)	splice site	probably benign
IGL00772:Dnah2	APN	11	69,342,083 (GRCm39)	missense	probably damaging	0.97
IGL00819:Dnah2	APN	11	69,364,176 (GRCm39)	critical splice donor site	probably null
IGL00827:Dnah2	APN	11	69,339,283 (GRCm39)	missense	probably damaging	1.00
IGL01060:Dnah2	APN	11	69,368,918 (GRCm39)	missense	possibly damaging	0.86
IGL01340:Dnah2	APN	11	69,384,010 (GRCm39)	missense	probably damaging	0.99
IGL01349:Dnah2	APN	11	69,366,432 (GRCm39)	missense	probably damaging	0.99
IGL01413:Dnah2	APN	11	69,323,790 (GRCm39)	missense	probably damaging	0.99
IGL01451:Dnah2	APN	11	69,365,017 (GRCm39)	splice site	probably benign
IGL01480:Dnah2	APN	11	69,349,197 (GRCm39)	missense	possibly damaging	0.91
IGL01537:Dnah2	APN	11	69,406,906 (GRCm39)	missense	probably benign	0.17
IGL01592:Dnah2	APN	11	69,321,913 (GRCm39)	missense	probably benign	0.14
IGL01612:Dnah2	APN	11	69,355,889 (GRCm39)	splice site	probably benign
IGL01667:Dnah2	APN	11	69,435,221 (GRCm39)	missense	probably benign
IGL01667:Dnah2	APN	11	69,411,767 (GRCm39)	missense	probably damaging	0.98
IGL01691:Dnah2	APN	11	69,430,269 (GRCm39)	missense	probably benign
IGL02019:Dnah2	APN	11	69,365,111 (GRCm39)	missense	probably damaging	1.00
IGL02039:Dnah2	APN	11	69,390,038 (GRCm39)	missense	probably damaging	1.00
IGL02076:Dnah2	APN	11	69,313,385 (GRCm39)	missense	probably damaging	0.99
IGL02085:Dnah2	APN	11	69,349,011 (GRCm39)	missense	probably benign	0.07
IGL02158:Dnah2	APN	11	69,348,949 (GRCm39)	missense	probably benign
IGL02381:Dnah2	APN	11	69,337,118 (GRCm39)	missense	probably benign	0.25
IGL02681:Dnah2	APN	11	69,343,759 (GRCm39)	missense	probably benign	0.40
IGL02957:Dnah2	APN	11	69,339,333 (GRCm39)	missense	possibly damaging	0.96
IGL02961:Dnah2	APN	11	69,409,240 (GRCm39)	missense	probably damaging	1.00
IGL02969:Dnah2	APN	11	69,412,013 (GRCm39)	missense	possibly damaging	0.80
IGL03117:Dnah2	APN	11	69,327,117 (GRCm39)	splice site	probably benign
IGL03120:Dnah2	APN	11	69,312,674 (GRCm39)	missense	probably damaging	1.00
IGL03183:Dnah2	APN	11	69,349,314 (GRCm39)	missense	possibly damaging	0.94
IGL03197:Dnah2	APN	11	69,350,089 (GRCm39)	missense	probably damaging	1.00
IGL03263:Dnah2	APN	11	69,420,207 (GRCm39)	critical splice donor site	probably null
IGL03333:Dnah2	APN	11	69,385,949 (GRCm39)	missense	probably damaging	1.00
IGL03338:Dnah2	APN	11	69,387,403 (GRCm39)	missense	probably benign	0.13
argyrios	UTSW	11	69,407,416 (GRCm39)	missense	possibly damaging	0.47
Aureus	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
platinum	UTSW	11	69,348,868 (GRCm39)	missense	probably damaging	0.96
R0334_dnah2_144	UTSW	11	69,327,662 (GRCm39)	missense	probably damaging	1.00
R2150_dnah2_212	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
BB005:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
BB015:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
E0370:Dnah2	UTSW	11	69,406,441 (GRCm39)	splice site	probably null
P0026:Dnah2	UTSW	11	69,355,773 (GRCm39)	missense	probably damaging	1.00
R0133:Dnah2	UTSW	11	69,311,835 (GRCm39)	missense	probably damaging	1.00
R0190:Dnah2	UTSW	11	69,326,075 (GRCm39)	missense	probably damaging	1.00
R0334:Dnah2	UTSW	11	69,327,662 (GRCm39)	missense	probably damaging	1.00
R0359:Dnah2	UTSW	11	69,420,357 (GRCm39)	missense	probably benign	0.00
R0386:Dnah2	UTSW	11	69,338,687 (GRCm39)	missense	probably damaging	1.00
R0414:Dnah2	UTSW	11	69,390,064 (GRCm39)	missense	probably benign	0.26
R0427:Dnah2	UTSW	11	69,343,705 (GRCm39)	missense	probably damaging	0.99
R0433:Dnah2	UTSW	11	69,350,114 (GRCm39)	missense	probably damaging	1.00
R0442:Dnah2	UTSW	11	69,339,368 (GRCm39)	missense	probably damaging	1.00
R0462:Dnah2	UTSW	11	69,350,027 (GRCm39)	missense	probably damaging	1.00
R0463:Dnah2	UTSW	11	69,313,952 (GRCm39)	missense	probably damaging	1.00
R0611:Dnah2	UTSW	11	69,390,020 (GRCm39)	missense	probably damaging	1.00
R0626:Dnah2	UTSW	11	69,368,509 (GRCm39)	missense	probably benign	0.07
R0924:Dnah2	UTSW	11	69,312,134 (GRCm39)	missense	probably damaging	1.00
R0968:Dnah2	UTSW	11	69,339,345 (GRCm39)	missense	possibly damaging	0.67
R1066:Dnah2	UTSW	11	69,338,645 (GRCm39)	missense	probably damaging	1.00
R1183:Dnah2	UTSW	11	69,337,474 (GRCm39)	missense	possibly damaging	0.95
R1184:Dnah2	UTSW	11	69,390,016 (GRCm39)	missense	probably damaging	1.00
R1186:Dnah2	UTSW	11	69,406,526 (GRCm39)	missense	probably damaging	0.99
R1453:Dnah2	UTSW	11	69,341,876 (GRCm39)	missense	probably damaging	0.99
R1498:Dnah2	UTSW	11	69,411,493 (GRCm39)	splice site	probably null
R1538:Dnah2	UTSW	11	69,368,028 (GRCm39)	missense	probably benign	0.17
R1574:Dnah2	UTSW	11	69,405,514 (GRCm39)	missense	probably benign	0.26
R1574:Dnah2	UTSW	11	69,405,514 (GRCm39)	missense	probably benign	0.26
R1590:Dnah2	UTSW	11	69,412,024 (GRCm39)	missense	probably benign	0.00
R1590:Dnah2	UTSW	11	69,313,580 (GRCm39)	critical splice donor site	probably null
R1655:Dnah2	UTSW	11	69,364,680 (GRCm39)	missense	probably damaging	1.00
R1695:Dnah2	UTSW	11	69,405,517 (GRCm39)	missense	possibly damaging	0.74
R1726:Dnah2	UTSW	11	69,388,715 (GRCm39)	missense	probably damaging	1.00
R1764:Dnah2	UTSW	11	69,314,369 (GRCm39)	missense	probably damaging	1.00
R1815:Dnah2	UTSW	11	69,366,400 (GRCm39)	missense	probably damaging	1.00
R1822:Dnah2	UTSW	11	69,405,630 (GRCm39)	missense	probably damaging	1.00
R1859:Dnah2	UTSW	11	69,328,712 (GRCm39)	missense	probably damaging	0.99
R1911:Dnah2	UTSW	11	69,406,578 (GRCm39)	missense	possibly damaging	0.64
R1913:Dnah2	UTSW	11	69,355,756 (GRCm39)	missense	probably damaging	1.00
R1981:Dnah2	UTSW	11	69,365,151 (GRCm39)	missense	probably damaging	1.00
R2010:Dnah2	UTSW	11	69,349,184 (GRCm39)	critical splice donor site	probably null
R2016:Dnah2	UTSW	11	69,327,896 (GRCm39)	missense	probably damaging	0.97
R2017:Dnah2	UTSW	11	69,327,896 (GRCm39)	missense	probably damaging	0.97
R2044:Dnah2	UTSW	11	69,415,066 (GRCm39)	missense	probably benign	0.14
R2077:Dnah2	UTSW	11	69,387,432 (GRCm39)	missense	possibly damaging	0.73
R2096:Dnah2	UTSW	11	69,346,742 (GRCm39)	missense	probably damaging	0.98
R2099:Dnah2	UTSW	11	69,384,063 (GRCm39)	missense	probably damaging	1.00
R2127:Dnah2	UTSW	11	69,349,011 (GRCm39)	missense	probably benign	0.02
R2128:Dnah2	UTSW	11	69,349,011 (GRCm39)	missense	probably benign	0.02
R2146:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2147:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2150:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2404:Dnah2	UTSW	11	69,328,047 (GRCm39)	missense	probably damaging	0.99
R2510:Dnah2	UTSW	11	69,415,032 (GRCm39)	nonsense	probably null
R2517:Dnah2	UTSW	11	69,407,470 (GRCm39)	missense	probably damaging	1.00
R3014:Dnah2	UTSW	11	69,321,304 (GRCm39)	missense	probably benign
R3741:Dnah2	UTSW	11	69,339,295 (GRCm39)	missense	probably damaging	1.00
R3814:Dnah2	UTSW	11	69,383,476 (GRCm39)	splice site	probably null
R3872:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3873:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3874:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3875:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3881:Dnah2	UTSW	11	69,342,173 (GRCm39)	missense	possibly damaging	0.94
R3953:Dnah2	UTSW	11	69,344,929 (GRCm39)	missense	probably damaging	1.00
R3956:Dnah2	UTSW	11	69,374,847 (GRCm39)	missense	probably benign	0.00
R4515:Dnah2	UTSW	11	69,356,457 (GRCm39)	missense	possibly damaging	0.61
R4612:Dnah2	UTSW	11	69,374,193 (GRCm39)	missense	possibly damaging	0.93
R4625:Dnah2	UTSW	11	69,354,487 (GRCm39)	missense	probably damaging	1.00
R4627:Dnah2	UTSW	11	69,356,202 (GRCm39)	missense	probably damaging	1.00
R4642:Dnah2	UTSW	11	69,387,385 (GRCm39)	missense	probably benign	0.00
R4683:Dnah2	UTSW	11	69,349,768 (GRCm39)	missense	probably damaging	1.00
R4698:Dnah2	UTSW	11	69,389,358 (GRCm39)	missense	probably damaging	1.00
R4710:Dnah2	UTSW	11	69,368,903 (GRCm39)	missense	probably damaging	1.00
R4712:Dnah2	UTSW	11	69,407,416 (GRCm39)	missense	possibly damaging	0.47
R4713:Dnah2	UTSW	11	69,367,514 (GRCm39)	missense	probably damaging	1.00
R4717:Dnah2	UTSW	11	69,320,183 (GRCm39)	missense	probably benign	0.00
R4740:Dnah2	UTSW	11	69,348,868 (GRCm39)	missense	probably damaging	0.96
R4780:Dnah2	UTSW	11	69,364,697 (GRCm39)	missense	probably damaging	0.97
R4825:Dnah2	UTSW	11	69,314,031 (GRCm39)	missense	probably damaging	1.00
R4864:Dnah2	UTSW	11	69,313,416 (GRCm39)	missense	probably damaging	0.98
R4868:Dnah2	UTSW	11	69,354,474 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah2	UTSW	11	69,367,517 (GRCm39)	missense	probably damaging	1.00
R4908:Dnah2	UTSW	11	69,411,973 (GRCm39)	missense	probably benign	0.00
R4911:Dnah2	UTSW	11	69,389,930 (GRCm39)	critical splice donor site	probably null
R4954:Dnah2	UTSW	11	69,430,322 (GRCm39)	missense	possibly damaging	0.61
R4962:Dnah2	UTSW	11	69,346,799 (GRCm39)	nonsense	probably null
R5015:Dnah2	UTSW	11	69,388,708 (GRCm39)	missense	possibly damaging	0.89
R5049:Dnah2	UTSW	11	69,338,992 (GRCm39)	missense	probably damaging	1.00
R5055:Dnah2	UTSW	11	69,411,599 (GRCm39)	missense	possibly damaging	0.67
R5153:Dnah2	UTSW	11	69,411,759 (GRCm39)	missense	possibly damaging	0.84
R5155:Dnah2	UTSW	11	69,313,362 (GRCm39)	missense	probably damaging	1.00
R5186:Dnah2	UTSW	11	69,326,710 (GRCm39)	missense	probably damaging	1.00
R5187:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5208:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5252:Dnah2	UTSW	11	69,420,295 (GRCm39)	missense	probably damaging	0.98
R5296:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5298:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5299:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5301:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5324:Dnah2	UTSW	11	69,348,819 (GRCm39)	missense	probably benign	0.07
R5350:Dnah2	UTSW	11	69,406,862 (GRCm39)	missense	possibly damaging	0.48
R5377:Dnah2	UTSW	11	69,312,674 (GRCm39)	missense	probably damaging	1.00
R5393:Dnah2	UTSW	11	69,391,683 (GRCm39)	missense	probably benign
R5421:Dnah2	UTSW	11	69,326,462 (GRCm39)	missense	probably damaging	1.00
R5452:Dnah2	UTSW	11	69,415,209 (GRCm39)	missense	probably damaging	1.00
R5461:Dnah2	UTSW	11	69,364,177 (GRCm39)	critical splice donor site	probably null
R5474:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5476:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5477:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5510:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5527:Dnah2	UTSW	11	69,328,014 (GRCm39)	nonsense	probably null
R5566:Dnah2	UTSW	11	69,407,395 (GRCm39)	nonsense	probably null
R5587:Dnah2	UTSW	11	69,328,068 (GRCm39)	missense	probably damaging	1.00
R5628:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5688:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5690:Dnah2	UTSW	11	69,382,370 (GRCm39)	missense	probably benign	0.15
R5711:Dnah2	UTSW	11	69,326,216 (GRCm39)	missense	probably damaging	1.00
R5735:Dnah2	UTSW	11	69,321,643 (GRCm39)	missense	possibly damaging	0.93
R5826:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5913:Dnah2	UTSW	11	69,339,256 (GRCm39)	missense	probably damaging	1.00
R5914:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5960:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5961:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5961:Dnah2	UTSW	11	69,321,974 (GRCm39)	missense	probably damaging	1.00
R5977:Dnah2	UTSW	11	69,411,707 (GRCm39)	missense	possibly damaging	0.79
R6020:Dnah2	UTSW	11	69,391,665 (GRCm39)	missense	probably benign
R6036:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6036:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6050:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6086:Dnah2	UTSW	11	69,406,834 (GRCm39)	missense	probably benign	0.30
R6115:Dnah2	UTSW	11	69,337,475 (GRCm39)	missense	probably damaging	1.00
R6123:Dnah2	UTSW	11	69,409,185 (GRCm39)	missense	probably benign	0.29
R6159:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6159:Dnah2	UTSW	11	69,349,368 (GRCm39)	missense	probably damaging	1.00
R6163:Dnah2	UTSW	11	69,411,729 (GRCm39)	nonsense	probably null
R6171:Dnah2	UTSW	11	69,313,868 (GRCm39)	missense	probably damaging	1.00
R6263:Dnah2	UTSW	11	69,348,238 (GRCm39)	missense	probably damaging	1.00
R6298:Dnah2	UTSW	11	69,382,467 (GRCm39)	missense	probably benign	0.25
R6352:Dnah2	UTSW	11	69,339,053 (GRCm39)	missense	probably damaging	1.00
R6399:Dnah2	UTSW	11	69,349,344 (GRCm39)	missense	probably damaging	0.98
R6466:Dnah2	UTSW	11	69,430,241 (GRCm39)	missense	probably benign
R6478:Dnah2	UTSW	11	69,406,836 (GRCm39)	missense	probably benign	0.01
R6516:Dnah2	UTSW	11	69,356,212 (GRCm39)	missense	probably benign	0.34
R6538:Dnah2	UTSW	11	69,328,023 (GRCm39)	missense	possibly damaging	0.87
R6802:Dnah2	UTSW	11	69,314,516 (GRCm39)	missense	probably damaging	1.00
R6861:Dnah2	UTSW	11	69,346,789 (GRCm39)	missense	possibly damaging	0.64
R6869:Dnah2	UTSW	11	69,320,297 (GRCm39)	missense	probably damaging	1.00
R6894:Dnah2	UTSW	11	69,375,086 (GRCm39)	missense	probably benign	0.12
R6935:Dnah2	UTSW	11	69,312,567 (GRCm39)	missense	probably damaging	1.00
R7017:Dnah2	UTSW	11	69,382,373 (GRCm39)	nonsense	probably null
R7073:Dnah2	UTSW	11	69,321,318 (GRCm39)	nonsense	probably null
R7111:Dnah2	UTSW	11	69,337,579 (GRCm39)	splice site	probably null
R7125:Dnah2	UTSW	11	69,327,008 (GRCm39)	missense	probably damaging	0.99
R7137:Dnah2	UTSW	11	69,382,381 (GRCm39)	missense	probably damaging	1.00
R7190:Dnah2	UTSW	11	69,439,923 (GRCm39)	splice site	probably null
R7214:Dnah2	UTSW	11	69,321,935 (GRCm39)	missense	probably damaging	1.00
R7227:Dnah2	UTSW	11	69,312,222 (GRCm39)	missense	probably damaging	0.99
R7238:Dnah2	UTSW	11	69,349,972 (GRCm39)	critical splice donor site	probably null
R7256:Dnah2	UTSW	11	69,321,920 (GRCm39)	missense	probably damaging	1.00
R7267:Dnah2	UTSW	11	69,391,643 (GRCm39)	missense	probably damaging	1.00
R7420:Dnah2	UTSW	11	69,369,623 (GRCm39)	missense	possibly damaging	0.94
R7421:Dnah2	UTSW	11	69,383,631 (GRCm39)	missense	probably benign	0.25
R7437:Dnah2	UTSW	11	69,389,453 (GRCm39)	missense	probably damaging	1.00
R7461:Dnah2	UTSW	11	69,439,816 (GRCm39)	critical splice donor site	probably null
R7473:Dnah2	UTSW	11	69,382,484 (GRCm39)	missense	probably damaging	0.99
R7528:Dnah2	UTSW	11	69,391,622 (GRCm39)	missense	probably damaging	0.99
R7613:Dnah2	UTSW	11	69,439,816 (GRCm39)	critical splice donor site	probably null
R7615:Dnah2	UTSW	11	69,326,130 (GRCm39)	missense	probably damaging	0.99
R7626:Dnah2	UTSW	11	69,389,511 (GRCm39)	missense	probably damaging	0.99
R7745:Dnah2	UTSW	11	69,342,144 (GRCm39)	nonsense	probably null
R7764:Dnah2	UTSW	11	69,348,984 (GRCm39)	missense	probably benign	0.29
R7793:Dnah2	UTSW	11	69,386,040 (GRCm39)	missense	probably benign	0.00
R7819:Dnah2	UTSW	11	69,407,419 (GRCm39)	missense	probably benign	0.01
R7881:Dnah2	UTSW	11	69,322,064 (GRCm39)	missense	probably damaging	1.00
R7900:Dnah2	UTSW	11	69,409,254 (GRCm39)	missense	probably damaging	1.00
R7916:Dnah2	UTSW	11	69,311,974 (GRCm39)	critical splice acceptor site	probably null
R7921:Dnah2	UTSW	11	69,411,660 (GRCm39)	missense	probably benign
R7928:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
R7937:Dnah2	UTSW	11	69,408,511 (GRCm39)	nonsense	probably null
R7995:Dnah2	UTSW	11	69,411,563 (GRCm39)	missense	possibly damaging	0.77
R8202:Dnah2	UTSW	11	69,369,649 (GRCm39)	missense	probably benign	0.00
R8208:Dnah2	UTSW	11	69,411,678 (GRCm39)	missense	probably benign	0.05
R8215:Dnah2	UTSW	11	69,326,193 (GRCm39)	missense	probably damaging	1.00
R8279:Dnah2	UTSW	11	69,366,399 (GRCm39)	missense	probably damaging	1.00
R8338:Dnah2	UTSW	11	69,378,122 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah2	UTSW	11	69,320,273 (GRCm39)	missense	possibly damaging	0.95
R8405:Dnah2	UTSW	11	69,349,289 (GRCm39)	missense	probably damaging	1.00
R8407:Dnah2	UTSW	11	69,350,104 (GRCm39)	missense	probably benign	0.00
R8493:Dnah2	UTSW	11	69,343,804 (GRCm39)	missense	probably damaging	1.00
R8673:Dnah2	UTSW	11	69,405,523 (GRCm39)	missense	probably benign	0.23
R8725:Dnah2	UTSW	11	69,415,005 (GRCm39)	missense	probably damaging	1.00
R8727:Dnah2	UTSW	11	69,415,005 (GRCm39)	missense	probably damaging	1.00
R8730:Dnah2	UTSW	11	69,384,087 (GRCm39)	missense	possibly damaging	0.73
R8804:Dnah2	UTSW	11	69,356,511 (GRCm39)	missense	probably benign	0.01
R8876:Dnah2	UTSW	11	69,382,348 (GRCm39)	missense	probably damaging	1.00
R8894:Dnah2	UTSW	11	69,383,048 (GRCm39)	missense	probably benign	0.01
R8938:Dnah2	UTSW	11	69,328,754 (GRCm39)	missense	probably damaging	0.99
R9044:Dnah2	UTSW	11	69,420,247 (GRCm39)	missense	probably benign
R9085:Dnah2	UTSW	11	69,320,224 (GRCm39)	missense	possibly damaging	0.69
R9110:Dnah2	UTSW	11	69,435,208 (GRCm39)	missense	probably benign
R9156:Dnah2	UTSW	11	69,313,687 (GRCm39)	missense
R9251:Dnah2	UTSW	11	69,406,619 (GRCm39)	missense	probably damaging	1.00
R9258:Dnah2	UTSW	11	69,368,079 (GRCm39)	missense	probably damaging	1.00
R9279:Dnah2	UTSW	11	69,409,104 (GRCm39)	missense	probably benign	0.01
R9318:Dnah2	UTSW	11	69,375,155 (GRCm39)	missense	probably benign	0.07
R9321:Dnah2	UTSW	11	69,338,939 (GRCm39)	critical splice donor site	probably null
R9350:Dnah2	UTSW	11	69,384,073 (GRCm39)	missense	probably benign	0.10
R9358:Dnah2	UTSW	11	69,406,592 (GRCm39)	missense	probably damaging	0.99
R9417:Dnah2	UTSW	11	69,326,990 (GRCm39)	missense	probably damaging	1.00
R9420:Dnah2	UTSW	11	69,368,942 (GRCm39)	missense	probably benign	0.09
R9438:Dnah2	UTSW	11	69,364,220 (GRCm39)	missense	probably damaging	1.00
R9469:Dnah2	UTSW	11	69,321,896 (GRCm39)	missense	probably damaging	1.00
R9487:Dnah2	UTSW	11	69,406,617 (GRCm39)	missense	possibly damaging	0.47
R9495:Dnah2	UTSW	11	69,345,208 (GRCm39)	missense	possibly damaging	0.89
R9579:Dnah2	UTSW	11	69,368,041 (GRCm39)	missense	probably damaging	1.00
R9608:Dnah2	UTSW	11	69,344,888 (GRCm39)	missense	probably null	1.00
R9651:Dnah2	UTSW	11	69,341,824 (GRCm39)	critical splice donor site	probably null
R9662:Dnah2	UTSW	11	69,343,763 (GRCm39)	missense	probably benign
RF004:Dnah2	UTSW	11	69,328,013 (GRCm39)	missense	probably benign	0.24
U24488:Dnah2	UTSW	11	69,374,648 (GRCm39)	missense	probably damaging	0.99
X0021:Dnah2	UTSW	11	69,339,388 (GRCm39)	missense	possibly damaging	0.81
Z1088:Dnah2	UTSW	11	69,321,619 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,312,647 (GRCm39)	missense	possibly damaging	0.46
Z1176:Dnah2	UTSW	11	69,407,349 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,407,307 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,389,493 (GRCm39)	missense	probably benign	0.12
Z1176:Dnah2	UTSW	11	69,377,880 (GRCm39)	missense	possibly damaging	0.46
Z1176:Dnah2	UTSW	11	69,341,946 (GRCm39)	missense	probably benign
Z1177:Dnah2	UTSW	11	69,435,383 (GRCm39)	critical splice acceptor site	probably null
Z1177:Dnah2	UTSW	11	69,354,279 (GRCm39)	missense	possibly damaging	0.63

Predicted Primers

PCR Primer
(F):5'- CTAACTCTGCTCTGCATGGTG -3'
(R):5'- TCTCATACCCCAAGAGCTGG -3'

Sequencing Primer
(F):5'- GCATGGTGCACTCCTCC -3'
(R):5'- AAGAGCTGGAACCGCTGCTC -3'

Posted On

2015-07-21