Incidental Mutation 'R0105:Prrc2b'
| ID |
33236 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prrc2b
|
| Ensembl Gene |
ENSMUSG00000039262 |
| Gene Name |
proline-rich coiled-coil 2B |
| Synonyms |
5830434P21Rik, Bat2l |
| MMRRC Submission |
038391-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0105 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
2 |
| Chromosomal Location |
32041094-32124549 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to T
at 32103323 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Stop codon
at position 934
(E934*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000064892
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036691]
[ENSMUST00000069817]
|
| AlphaFold |
Q7TPM1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036691
|
| SMART Domains |
Protein: ENSMUSP00000035734
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
194 |
2.7e-85 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1007 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1126 |
N/A |
INTRINSIC |
|
low complexity region
|
1218 |
1233 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1421 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1437 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000069817
AA Change: E934*
|
| SMART Domains |
Protein: ENSMUSP00000064892
Gene: ENSMUSG00000039262
AA Change: E934*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
191 |
3.1e-65 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1018 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1307 |
1325 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1401 |
N/A |
INTRINSIC |
|
low complexity region
|
1413 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1572 |
1587 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1693 |
N/A |
INTRINSIC |
|
low complexity region
|
1798 |
1812 |
N/A |
INTRINSIC |
|
low complexity region
|
1904 |
1919 |
N/A |
INTRINSIC |
|
low complexity region
|
1943 |
1961 |
N/A |
INTRINSIC |
|
low complexity region
|
2088 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2111 |
2123 |
N/A |
INTRINSIC |
|
low complexity region
|
2161 |
2174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123270
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128936
|
| SMART Domains |
Protein: ENSMUSP00000121664
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
68 |
N/A |
INTRINSIC |
|
low complexity region
|
159 |
174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132459
|
| SMART Domains |
Protein: ENSMUSP00000116429
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
119 |
9.8e-24 |
PFAM |
|
low complexity region
|
287 |
302 |
N/A |
INTRINSIC |
|
low complexity region
|
316 |
322 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
352 |
N/A |
INTRINSIC |
|
coiled coil region
|
421 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
528 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
566 |
584 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
828 |
N/A |
INTRINSIC |
|
low complexity region
|
920 |
935 |
N/A |
INTRINSIC |
|
low complexity region
|
1040 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1146 |
1161 |
N/A |
INTRINSIC |
|
low complexity region
|
1185 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1349 |
N/A |
INTRINSIC |
|
low complexity region
|
1353 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1416 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140015
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142219
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156313
|
| SMART Domains |
Protein: ENSMUSP00000114994
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
125 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
231 |
246 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.9705 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.9%
|
| Validation Efficiency |
100% (70/70) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 66 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5530400C23Rik |
G |
A |
6: 133,271,277 (GRCm39) |
R107K |
probably benign |
Het |
| A530053G22Rik |
T |
C |
6: 60,379,137 (GRCm39) |
|
noncoding transcript |
Het |
| Adcy9 |
A |
G |
16: 4,106,252 (GRCm39) |
V954A |
probably damaging |
Het |
| Aldh8a1 |
T |
A |
10: 21,271,438 (GRCm39) |
M388K |
probably damaging |
Het |
| Ankhd1 |
A |
G |
18: 36,779,819 (GRCm39) |
I1720M |
probably damaging |
Het |
| Atp6v0a4 |
T |
C |
6: 38,030,064 (GRCm39) |
|
probably benign |
Het |
| C1qtnf4 |
T |
A |
2: 90,720,707 (GRCm39) |
*327R |
probably null |
Het |
| C1s1 |
T |
C |
6: 124,518,277 (GRCm39) |
|
probably benign |
Het |
| Cdsn |
A |
C |
17: 35,867,035 (GRCm39) |
R521S |
possibly damaging |
Het |
| Cgnl1 |
T |
C |
9: 71,563,384 (GRCm39) |
M848V |
probably benign |
Het |
| Cog3 |
A |
G |
14: 75,959,580 (GRCm39) |
S591P |
probably damaging |
Het |
| Col6a3 |
A |
G |
1: 90,725,883 (GRCm39) |
V1375A |
possibly damaging |
Het |
| Cplane1 |
T |
A |
15: 8,216,876 (GRCm39) |
V698D |
probably benign |
Het |
| Cr1l |
A |
G |
1: 194,794,720 (GRCm39) |
|
probably benign |
Het |
| Crmp1 |
T |
A |
5: 37,441,479 (GRCm39) |
D520E |
probably damaging |
Het |
| Ctdspl2 |
T |
A |
2: 121,807,801 (GRCm39) |
|
probably benign |
Het |
| Dnah6 |
C |
T |
6: 73,132,262 (GRCm39) |
A1147T |
probably damaging |
Het |
| Dsg2 |
T |
C |
18: 20,735,111 (GRCm39) |
S1030P |
probably benign |
Het |
| Elavl3 |
C |
A |
9: 21,948,129 (GRCm39) |
V12F |
possibly damaging |
Het |
| Fam20b |
T |
C |
1: 156,518,140 (GRCm39) |
E218G |
probably damaging |
Het |
| Fam227a |
T |
C |
15: 79,505,033 (GRCm39) |
D466G |
possibly damaging |
Het |
| Fto |
G |
A |
8: 92,249,430 (GRCm39) |
E421K |
probably damaging |
Het |
| Gab2 |
T |
C |
7: 96,948,279 (GRCm39) |
Y290H |
probably damaging |
Het |
| Gm973 |
A |
G |
1: 59,621,633 (GRCm39) |
Q591R |
probably null |
Het |
| Gsdmc2 |
T |
C |
15: 63,700,026 (GRCm39) |
T249A |
probably benign |
Het |
| Il15ra |
T |
A |
2: 11,735,459 (GRCm39) |
|
probably null |
Het |
| Il1rl1 |
CTTGTTGTTGTTGTTGTTG |
CTTGTTGTTGTTGTTGTTGTTG |
1: 40,481,734 (GRCm39) |
|
probably benign |
Het |
| Il6ra |
A |
G |
3: 89,784,125 (GRCm39) |
I382T |
probably damaging |
Het |
| Isy1 |
G |
A |
6: 87,796,167 (GRCm39) |
R257W |
probably damaging |
Het |
| Krt76 |
T |
C |
15: 101,793,347 (GRCm39) |
T564A |
unknown |
Het |
| Lhpp |
T |
C |
7: 132,232,254 (GRCm39) |
S57P |
probably damaging |
Het |
| Lrrk1 |
G |
T |
7: 65,942,089 (GRCm39) |
D716E |
probably damaging |
Het |
| Mcm3ap |
T |
A |
10: 76,335,368 (GRCm39) |
D1263E |
probably damaging |
Het |
| Mogat1 |
A |
G |
1: 78,500,307 (GRCm39) |
T124A |
probably benign |
Het |
| Mroh7 |
T |
C |
4: 106,568,467 (GRCm39) |
T48A |
possibly damaging |
Het |
| Nccrp1 |
T |
C |
7: 28,246,463 (GRCm39) |
D33G |
probably benign |
Het |
| Neurog1 |
G |
T |
13: 56,399,050 (GRCm39) |
D232E |
probably benign |
Het |
| Or4a71 |
T |
C |
2: 89,358,707 (GRCm39) |
T16A |
probably benign |
Het |
| Or4c105 |
T |
A |
2: 88,648,253 (GRCm39) |
V246D |
probably damaging |
Het |
| Otog |
C |
A |
7: 45,937,790 (GRCm39) |
T1833K |
possibly damaging |
Het |
| Perm1 |
C |
A |
4: 156,302,682 (GRCm39) |
H409N |
probably benign |
Het |
| Pik3r5 |
A |
T |
11: 68,381,337 (GRCm39) |
E174D |
probably damaging |
Het |
| Pkhd1 |
G |
A |
1: 20,593,956 (GRCm39) |
Q1386* |
probably null |
Het |
| Pla2r1 |
T |
C |
2: 60,345,325 (GRCm39) |
R344G |
possibly damaging |
Het |
| Plekha5 |
G |
A |
6: 140,537,473 (GRCm39) |
R646K |
possibly damaging |
Het |
| Plekhg4 |
G |
A |
8: 106,108,644 (GRCm39) |
V1202M |
possibly damaging |
Het |
| Ppil4 |
A |
G |
10: 7,674,210 (GRCm39) |
Y118C |
probably damaging |
Het |
| Psmb9 |
A |
G |
17: 34,406,249 (GRCm39) |
F12S |
probably benign |
Het |
| Ptdss2 |
T |
C |
7: 140,732,793 (GRCm39) |
W183R |
probably damaging |
Het |
| Ptpn4 |
C |
T |
1: 119,615,335 (GRCm39) |
|
probably null |
Het |
| Reln |
G |
A |
5: 22,253,813 (GRCm39) |
R600W |
probably damaging |
Het |
| Scml4 |
T |
A |
10: 42,806,595 (GRCm39) |
V161E |
probably damaging |
Het |
| Sdcbp2 |
A |
T |
2: 151,431,478 (GRCm39) |
T284S |
probably benign |
Het |
| Slc22a29 |
T |
C |
19: 8,137,991 (GRCm39) |
|
probably benign |
Het |
| Slc35e1 |
T |
C |
8: 73,246,415 (GRCm39) |
|
probably benign |
Het |
| Spen |
T |
C |
4: 141,197,121 (GRCm39) |
|
probably benign |
Het |
| Sumf2 |
T |
A |
5: 129,878,735 (GRCm39) |
|
probably benign |
Het |
| Tbx10 |
A |
G |
19: 4,043,121 (GRCm39) |
|
probably benign |
Het |
| Tex10 |
C |
A |
4: 48,468,957 (GRCm39) |
V73F |
probably damaging |
Het |
| Tgm5 |
C |
A |
2: 120,907,493 (GRCm39) |
G77W |
probably damaging |
Het |
| Tnfrsf21 |
T |
A |
17: 43,351,082 (GRCm39) |
|
probably null |
Het |
| Treml2 |
C |
T |
17: 48,609,856 (GRCm39) |
T96I |
probably damaging |
Het |
| Trim65 |
T |
C |
11: 116,016,892 (GRCm39) |
*523W |
probably null |
Het |
| Zcchc17 |
T |
A |
4: 130,243,099 (GRCm39) |
D28V |
probably benign |
Het |
| Zhx2 |
T |
C |
15: 57,686,091 (GRCm39) |
F487L |
probably damaging |
Het |
| Zkscan6 |
T |
A |
11: 65,712,811 (GRCm39) |
L248Q |
probably damaging |
Het |
|
| Other mutations in Prrc2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00156:Prrc2b
|
APN |
2 |
32,098,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00846:Prrc2b
|
APN |
2 |
32,089,109 (GRCm39) |
splice site |
probably benign |
|
|
IGL00977:Prrc2b
|
APN |
2 |
32,103,822 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01372:Prrc2b
|
APN |
2 |
32,113,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01993:Prrc2b
|
APN |
2 |
32,114,057 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02097:Prrc2b
|
APN |
2 |
32,081,513 (GRCm39) |
splice site |
probably benign |
|
|
IGL02165:Prrc2b
|
APN |
2 |
32,104,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02184:Prrc2b
|
APN |
2 |
32,111,467 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02238:Prrc2b
|
APN |
2 |
32,103,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02338:Prrc2b
|
APN |
2 |
32,104,047 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02399:Prrc2b
|
APN |
2 |
32,116,973 (GRCm39) |
nonsense |
probably null |
|
|
IGL02597:Prrc2b
|
APN |
2 |
32,109,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02729:Prrc2b
|
APN |
2 |
32,098,770 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02743:Prrc2b
|
APN |
2 |
32,084,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Prrc2b
|
APN |
2 |
32,094,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03159:Prrc2b
|
APN |
2 |
32,084,498 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB002:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB012:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4304:Prrc2b
|
UTSW |
2 |
32,111,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0082:Prrc2b
|
UTSW |
2 |
32,102,310 (GRCm39) |
splice site |
probably benign |
|
|
R0276:Prrc2b
|
UTSW |
2 |
32,109,666 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0325:Prrc2b
|
UTSW |
2 |
32,089,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0436:Prrc2b
|
UTSW |
2 |
32,120,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0595:Prrc2b
|
UTSW |
2 |
32,073,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0607:Prrc2b
|
UTSW |
2 |
32,103,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0650:Prrc2b
|
UTSW |
2 |
32,119,267 (GRCm39) |
splice site |
probably benign |
|
|
R1282:Prrc2b
|
UTSW |
2 |
32,113,456 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1421:Prrc2b
|
UTSW |
2 |
32,090,990 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1452:Prrc2b
|
UTSW |
2 |
32,084,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Prrc2b
|
UTSW |
2 |
32,094,301 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1709:Prrc2b
|
UTSW |
2 |
32,084,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Prrc2b
|
UTSW |
2 |
32,102,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2094:Prrc2b
|
UTSW |
2 |
32,072,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2203:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2204:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2428:Prrc2b
|
UTSW |
2 |
32,106,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2435:Prrc2b
|
UTSW |
2 |
32,109,741 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3439:Prrc2b
|
UTSW |
2 |
32,096,359 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4175:Prrc2b
|
UTSW |
2 |
32,108,820 (GRCm39) |
intron |
probably benign |
|
|
R4710:Prrc2b
|
UTSW |
2 |
32,083,869 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4728:Prrc2b
|
UTSW |
2 |
32,120,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4791:Prrc2b
|
UTSW |
2 |
32,107,351 (GRCm39) |
splice site |
probably null |
|
|
R4876:Prrc2b
|
UTSW |
2 |
32,104,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4908:Prrc2b
|
UTSW |
2 |
32,116,330 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4997:Prrc2b
|
UTSW |
2 |
32,112,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5240:Prrc2b
|
UTSW |
2 |
32,096,408 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5276:Prrc2b
|
UTSW |
2 |
32,104,734 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5455:Prrc2b
|
UTSW |
2 |
32,111,355 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5821:Prrc2b
|
UTSW |
2 |
32,102,144 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5835:Prrc2b
|
UTSW |
2 |
32,096,485 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5958:Prrc2b
|
UTSW |
2 |
32,102,092 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6052:Prrc2b
|
UTSW |
2 |
32,102,297 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6218:Prrc2b
|
UTSW |
2 |
32,098,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Prrc2b
|
UTSW |
2 |
32,116,508 (GRCm39) |
splice site |
probably null |
|
|
R6505:Prrc2b
|
UTSW |
2 |
32,112,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6812:Prrc2b
|
UTSW |
2 |
32,103,153 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6826:Prrc2b
|
UTSW |
2 |
32,112,300 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6827:Prrc2b
|
UTSW |
2 |
32,090,963 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7021:Prrc2b
|
UTSW |
2 |
32,111,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7078:Prrc2b
|
UTSW |
2 |
32,103,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7081:Prrc2b
|
UTSW |
2 |
32,103,075 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7101:Prrc2b
|
UTSW |
2 |
32,117,005 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7215:Prrc2b
|
UTSW |
2 |
32,119,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7228:Prrc2b
|
UTSW |
2 |
32,104,318 (GRCm39) |
nonsense |
probably null |
|
|
R7566:Prrc2b
|
UTSW |
2 |
32,084,402 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7719:Prrc2b
|
UTSW |
2 |
32,107,280 (GRCm39) |
nonsense |
probably null |
|
|
R7925:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7999:Prrc2b
|
UTSW |
2 |
32,084,426 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8099:Prrc2b
|
UTSW |
2 |
32,098,686 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8154:Prrc2b
|
UTSW |
2 |
32,108,689 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8252:Prrc2b
|
UTSW |
2 |
32,109,392 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8379:Prrc2b
|
UTSW |
2 |
32,104,666 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8485:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,106,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8919:Prrc2b
|
UTSW |
2 |
32,104,953 (GRCm39) |
missense |
probably benign |
|
|
R8982:Prrc2b
|
UTSW |
2 |
32,102,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9065:Prrc2b
|
UTSW |
2 |
32,109,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9127:Prrc2b
|
UTSW |
2 |
32,103,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Prrc2b
|
UTSW |
2 |
32,103,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9338:Prrc2b
|
UTSW |
2 |
32,098,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9344:Prrc2b
|
UTSW |
2 |
32,103,600 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9386:Prrc2b
|
UTSW |
2 |
32,104,125 (GRCm39) |
missense |
probably benign |
|
|
R9601:Prrc2b
|
UTSW |
2 |
32,090,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9607:Prrc2b
|
UTSW |
2 |
32,098,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9670:Prrc2b
|
UTSW |
2 |
32,103,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9706:Prrc2b
|
UTSW |
2 |
32,107,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,106,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,104,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1177:Prrc2b
|
UTSW |
2 |
32,116,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTCCCCATTGGAGCCTGACTTTG -3'
(R):5'- AAAGACCACTTGTGCTGCTGCC -3'
Sequencing Primer
(F):5'- GAGCCTGACTTTGTCCCAG -3'
(R):5'- GGCCTGTTCCTCATCAATGAAG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation