Incidental Mutation 'IGL00539:Fpr-rs4'
| ID |
332564 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Fpr-rs4
|
| Ensembl Gene |
ENSMUSG00000048062 |
| Gene Name |
formyl peptide receptor, related sequence 4 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.084)
|
| Stock # |
IGL00539
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
18241995-18242966 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 18242188 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 65
(L65Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000093311
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000095651]
|
| AlphaFold |
A4FUQ5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000095651
AA Change: L65Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000093311
Gene: ENSMUSG00000048062
AA Change: L65Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:7tm_1
|
43 |
297 |
4.9e-35 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 26 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ahnak |
C |
A |
19: 8,985,272 (GRCm39) |
D2185E |
possibly damaging |
Het |
| Camk2b |
A |
G |
11: 5,922,310 (GRCm39) |
S560P |
probably damaging |
Het |
| Cdh13 |
C |
A |
8: 120,039,245 (GRCm39) |
N562K |
possibly damaging |
Het |
| Cdhr4 |
A |
G |
9: 107,876,744 (GRCm39) |
Y771C |
probably damaging |
Het |
| Ermap |
A |
G |
4: 119,041,114 (GRCm39) |
S299P |
probably damaging |
Het |
| Fgd3 |
A |
G |
13: 49,429,119 (GRCm39) |
|
probably benign |
Het |
| Hsph1 |
C |
T |
5: 149,542,254 (GRCm39) |
R723H |
possibly damaging |
Het |
| Iqcb1 |
A |
G |
16: 36,678,873 (GRCm39) |
K396E |
probably damaging |
Het |
| Kif21a |
T |
C |
15: 90,821,504 (GRCm39) |
T1424A |
probably damaging |
Het |
| Mpdz |
T |
C |
4: 81,279,588 (GRCm39) |
S700G |
possibly damaging |
Het |
| Mta3 |
G |
A |
17: 84,070,412 (GRCm39) |
R39Q |
probably benign |
Het |
| Muc4 |
A |
T |
16: 32,569,728 (GRCm39) |
T263S |
possibly damaging |
Het |
| Ncan |
G |
A |
8: 70,567,921 (GRCm39) |
P64S |
probably benign |
Het |
| Pisd |
T |
C |
5: 32,895,756 (GRCm39) |
I441V |
probably benign |
Het |
| Pla2g4f |
T |
C |
2: 120,133,219 (GRCm39) |
H660R |
possibly damaging |
Het |
| Polq |
A |
G |
16: 36,880,931 (GRCm39) |
T753A |
probably damaging |
Het |
| Ptchd4 |
C |
T |
17: 42,627,817 (GRCm39) |
Q93* |
probably null |
Het |
| Sfpq |
T |
C |
4: 126,917,481 (GRCm39) |
V437A |
possibly damaging |
Het |
| Slc18b1 |
G |
A |
10: 23,700,659 (GRCm39) |
|
probably null |
Het |
| Taf1c |
C |
T |
8: 120,328,067 (GRCm39) |
V277I |
possibly damaging |
Het |
| Tcf20 |
T |
A |
15: 82,736,957 (GRCm39) |
Q1498L |
probably benign |
Het |
| Tet1 |
C |
A |
10: 62,650,276 (GRCm39) |
C1644F |
probably damaging |
Het |
| Trmt5 |
T |
C |
12: 73,331,693 (GRCm39) |
E121G |
possibly damaging |
Het |
| Wapl |
A |
G |
14: 34,416,965 (GRCm39) |
D525G |
probably damaging |
Het |
| Ylpm1 |
A |
G |
12: 85,075,728 (GRCm39) |
T360A |
possibly damaging |
Het |
| Zfp292 |
G |
A |
4: 34,808,790 (GRCm39) |
P1418L |
probably damaging |
Het |
|
| Other mutations in Fpr-rs4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01064:Fpr-rs4
|
APN |
17 |
18,242,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01626:Fpr-rs4
|
APN |
17 |
18,242,493 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02544:Fpr-rs4
|
APN |
17 |
18,242,473 (GRCm39) |
missense |
probably benign |
|
|
IGL02837:Fpr-rs4
|
UTSW |
17 |
18,242,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0179:Fpr-rs4
|
UTSW |
17 |
18,242,289 (GRCm39) |
nonsense |
probably null |
|
|
R0383:Fpr-rs4
|
UTSW |
17 |
18,242,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0686:Fpr-rs4
|
UTSW |
17 |
18,242,613 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1551:Fpr-rs4
|
UTSW |
17 |
18,242,589 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1956:Fpr-rs4
|
UTSW |
17 |
18,242,518 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2040:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R2041:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R2043:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R2045:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R2048:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R2092:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R2093:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R2136:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R3624:Fpr-rs4
|
UTSW |
17 |
18,242,596 (GRCm39) |
frame shift |
probably null |
|
|
R4684:Fpr-rs4
|
UTSW |
17 |
18,242,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6076:Fpr-rs4
|
UTSW |
17 |
18,242,317 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Fpr-rs4
|
UTSW |
17 |
18,242,748 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6639:Fpr-rs4
|
UTSW |
17 |
18,242,394 (GRCm39) |
nonsense |
probably null |
|
|
R6757:Fpr-rs4
|
UTSW |
17 |
18,242,394 (GRCm39) |
nonsense |
probably null |
|
|
R8703:Fpr-rs4
|
UTSW |
17 |
18,242,332 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9007:Fpr-rs4
|
UTSW |
17 |
18,242,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9318:Fpr-rs4
|
UTSW |
17 |
18,242,217 (GRCm39) |
missense |
probably benign |
|
|
R9357:Fpr-rs4
|
UTSW |
17 |
18,242,211 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9435:Fpr-rs4
|
UTSW |
17 |
18,242,391 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Fpr-rs4
|
UTSW |
17 |
18,242,956 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1088:Fpr-rs4
|
UTSW |
17 |
18,242,181 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
| Posted On |
2015-08-05 |
Incidental Mutation