Incidental Mutation 'R4573:Pnpla7'
| ID |
342242 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pnpla7
|
| Ensembl Gene |
ENSMUSG00000036833 |
| Gene Name |
patatin-like phospholipase domain containing 7 |
| Synonyms |
NRE, E430013P11Rik |
| MMRRC Submission |
041598-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.151)
|
| Stock # |
R4573 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
24866045-24944069 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 24940885 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1079
(V1079A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000044078
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000006646]
[ENSMUST00000045295]
[ENSMUST00000074422]
[ENSMUST00000100334]
[ENSMUST00000102931]
[ENSMUST00000114386]
[ENSMUST00000114388]
[ENSMUST00000137913]
[ENSMUST00000140737]
[ENSMUST00000132172]
[ENSMUST00000116574]
[ENSMUST00000155601]
[ENSMUST00000144520]
[ENSMUST00000152122]
|
| AlphaFold |
A2AJ88 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000006646
|
| SMART Domains |
Protein: ENSMUSP00000006646
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
292 |
N/A |
INTRINSIC |
|
low complexity region
|
361 |
375 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000045295
AA Change: V1079A
PolyPhen 2
Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000044078
Gene: ENSMUSG00000036833
AA Change: V1079A
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
66 |
N/A |
INTRINSIC |
|
cNMP
|
170 |
295 |
2.06e-12 |
SMART |
|
low complexity region
|
439 |
444 |
N/A |
INTRINSIC |
|
cNMP
|
481 |
600 |
1.16e-6 |
SMART |
|
cNMP
|
603 |
716 |
1.55e-7 |
SMART |
|
Pfam:Patatin
|
950 |
1116 |
3.2e-24 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074422
|
| SMART Domains |
Protein: ENSMUSP00000074022
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
258 |
269 |
N/A |
INTRINSIC |
|
low complexity region
|
338 |
352 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100334
|
| SMART Domains |
Protein: ENSMUSP00000097908
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
283 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
363 |
377 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102931
|
| SMART Domains |
Protein: ENSMUSP00000099995
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
260 |
271 |
N/A |
INTRINSIC |
|
low complexity region
|
340 |
354 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114386
|
| SMART Domains |
Protein: ENSMUSP00000110028
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
310 |
324 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114388
|
| SMART Domains |
Protein: ENSMUSP00000110030
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
345 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132082
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000138536
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141584
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141866
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128517
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154359
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155909
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137913
|
| SMART Domains |
Protein: ENSMUSP00000141577
Gene: ENSMUSG00000036833
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
10 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
33 |
40 |
N/A |
INTRINSIC |
|
Pfam:cNMP_binding
|
162 |
200 |
2.7e-5 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140737
|
| SMART Domains |
Protein: ENSMUSP00000141410
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132172
|
| SMART Domains |
Protein: ENSMUSP00000116106
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000116574
|
| SMART Domains |
Protein: ENSMUSP00000112273
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
260 |
271 |
N/A |
INTRINSIC |
|
low complexity region
|
340 |
354 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155601
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144520
|
| SMART Domains |
Protein: ENSMUSP00000141583
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
283 |
294 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152122
|
| SMART Domains |
Protein: ENSMUSP00000121580
Gene: ENSMUSG00000006476
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
28 |
N/A |
INTRINSIC |
|
Pfam:IQ
|
62 |
80 |
2.5e-4 |
PFAM |
|
low complexity region
|
114 |
125 |
N/A |
INTRINSIC |
|
low complexity region
|
194 |
208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175104
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Human patatin-like phospholipases, such as PNPLA7, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM, Jun 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam15 |
T |
C |
3: 89,253,293 (GRCm39) |
E212G |
probably damaging |
Het |
| Adam1b |
A |
C |
5: 121,638,856 (GRCm39) |
S730A |
probably benign |
Het |
| Akr1b10 |
T |
C |
6: 34,369,064 (GRCm39) |
V153A |
probably damaging |
Het |
| Ap1m2 |
T |
C |
9: 21,217,054 (GRCm39) |
Y94C |
probably damaging |
Het |
| Arhgef33 |
T |
C |
17: 80,672,711 (GRCm39) |
S320P |
probably damaging |
Het |
| Arsg |
T |
C |
11: 109,408,108 (GRCm39) |
S87P |
probably damaging |
Het |
| Asic3 |
A |
G |
5: 24,622,190 (GRCm39) |
Y458C |
probably damaging |
Het |
| Aspm |
G |
T |
1: 139,407,245 (GRCm39) |
W2044L |
probably damaging |
Het |
| Atad2b |
T |
C |
12: 5,004,663 (GRCm39) |
|
probably null |
Het |
| Atp1a2 |
T |
C |
1: 172,106,204 (GRCm39) |
I869M |
possibly damaging |
Het |
| Bpifb2 |
C |
T |
2: 153,731,412 (GRCm39) |
L263F |
probably damaging |
Het |
| C1s2 |
T |
C |
6: 124,605,202 (GRCm39) |
|
probably null |
Het |
| Carf |
G |
T |
1: 60,187,271 (GRCm39) |
A590S |
probably benign |
Het |
| Cbarp |
G |
T |
10: 79,967,245 (GRCm39) |
D658E |
probably damaging |
Het |
| Cd1d2 |
A |
G |
3: 86,894,861 (GRCm39) |
I78V |
probably benign |
Het |
| Cdc42bpb |
A |
T |
12: 111,289,575 (GRCm39) |
M418K |
probably benign |
Het |
| Cdhr3 |
A |
T |
12: 33,118,152 (GRCm39) |
|
probably null |
Het |
| Cep290 |
A |
G |
10: 100,354,712 (GRCm39) |
K932R |
probably benign |
Het |
| Ces1d |
A |
C |
8: 93,908,162 (GRCm39) |
N310K |
probably benign |
Het |
| Chka |
A |
G |
19: 3,935,960 (GRCm39) |
K240R |
probably damaging |
Het |
| Cltb |
C |
T |
13: 54,746,574 (GRCm39) |
R64H |
probably damaging |
Het |
| Cyp4f37 |
A |
G |
17: 32,848,061 (GRCm39) |
E193G |
probably benign |
Het |
| Dhrs9 |
C |
A |
2: 69,227,985 (GRCm39) |
H200N |
probably benign |
Het |
| Dnah6 |
T |
A |
6: 73,063,164 (GRCm39) |
N2698I |
probably damaging |
Het |
| Dnah8 |
T |
C |
17: 30,919,380 (GRCm39) |
S1118P |
probably benign |
Het |
| Dyrk1a |
A |
G |
16: 94,492,882 (GRCm39) |
Y705C |
possibly damaging |
Het |
| Elmod1 |
T |
C |
9: 53,833,256 (GRCm39) |
N183S |
probably damaging |
Het |
| Fer1l6 |
G |
A |
15: 58,498,129 (GRCm39) |
|
probably null |
Het |
| Fsip2 |
A |
T |
2: 82,816,510 (GRCm39) |
Y4081F |
possibly damaging |
Het |
| Gsr |
A |
G |
8: 34,183,881 (GRCm39) |
D381G |
probably benign |
Het |
| Gucy1a1 |
A |
G |
3: 82,016,229 (GRCm39) |
L253S |
possibly damaging |
Het |
| Herc3 |
C |
A |
6: 58,871,098 (GRCm39) |
T69K |
possibly damaging |
Het |
| Hoxb13 |
A |
G |
11: 96,085,777 (GRCm39) |
Y170C |
probably damaging |
Het |
| Hsd3b5 |
T |
C |
3: 98,526,964 (GRCm39) |
M161V |
probably benign |
Het |
| Lrp6 |
G |
A |
6: 134,447,693 (GRCm39) |
R985* |
probably null |
Het |
| Marchf5 |
T |
A |
19: 37,197,793 (GRCm39) |
I154K |
probably damaging |
Het |
| Mcemp1 |
A |
G |
8: 3,715,835 (GRCm39) |
|
probably null |
Het |
| Mrpl2 |
G |
T |
17: 46,959,967 (GRCm39) |
C212F |
possibly damaging |
Het |
| Mterf1a |
G |
A |
5: 3,941,119 (GRCm39) |
R250W |
possibly damaging |
Het |
| Mthfd1 |
A |
G |
12: 76,340,912 (GRCm39) |
|
probably null |
Het |
| Mul1 |
T |
C |
4: 138,163,660 (GRCm39) |
F19L |
probably benign |
Het |
| Mycbp2 |
G |
T |
14: 103,583,733 (GRCm39) |
A74E |
probably benign |
Het |
| Myo5a |
A |
T |
9: 75,108,579 (GRCm39) |
|
probably null |
Het |
| Ncor2 |
A |
T |
5: 125,132,889 (GRCm39) |
S33T |
probably damaging |
Het |
| Niban1 |
T |
C |
1: 151,579,517 (GRCm39) |
V412A |
possibly damaging |
Het |
| Ninj1 |
A |
G |
13: 49,348,463 (GRCm39) |
N191S |
probably damaging |
Het |
| Nrap |
T |
C |
19: 56,330,770 (GRCm39) |
|
probably null |
Het |
| Ofcc1 |
G |
A |
13: 40,168,864 (GRCm39) |
T841I |
probably damaging |
Het |
| Or1j21 |
T |
A |
2: 36,683,491 (GRCm39) |
M81K |
probably damaging |
Het |
| Or1n1b |
T |
C |
2: 36,780,202 (GRCm39) |
I219M |
probably damaging |
Het |
| Osbpl5 |
C |
A |
7: 143,248,053 (GRCm39) |
V671L |
probably benign |
Het |
| Paics |
T |
C |
5: 77,104,450 (GRCm39) |
L25S |
probably benign |
Het |
| Pcmtd1 |
A |
G |
1: 7,190,591 (GRCm39) |
E20G |
probably damaging |
Het |
| Pgbd5 |
G |
A |
8: 125,102,966 (GRCm39) |
Q228* |
probably null |
Het |
| Pou2f1 |
G |
A |
1: 165,740,830 (GRCm39) |
T113I |
probably benign |
Het |
| Ppp1r14c |
A |
G |
10: 3,413,416 (GRCm39) |
I150V |
possibly damaging |
Het |
| Ppp1r2 |
A |
G |
16: 31,079,455 (GRCm39) |
Y115H |
possibly damaging |
Het |
| Ptchd4 |
T |
C |
17: 42,813,668 (GRCm39) |
V523A |
probably benign |
Het |
| Rabep1 |
G |
C |
11: 70,808,577 (GRCm39) |
S468T |
probably damaging |
Het |
| Rgs6 |
T |
A |
12: 83,112,789 (GRCm39) |
W200R |
probably damaging |
Het |
| Ryr3 |
C |
T |
2: 112,585,519 (GRCm39) |
|
probably null |
Het |
| Scamp2 |
A |
T |
9: 57,484,477 (GRCm39) |
D20V |
probably damaging |
Het |
| Sec24d |
G |
A |
3: 123,152,519 (GRCm39) |
V844M |
probably damaging |
Het |
| Septin10 |
T |
A |
10: 59,028,151 (GRCm39) |
N57Y |
probably damaging |
Het |
| Sis |
T |
C |
3: 72,835,570 (GRCm39) |
K931E |
possibly damaging |
Het |
| Slamf7 |
T |
C |
1: 171,463,934 (GRCm39) |
T258A |
probably benign |
Het |
| Slc15a1 |
A |
G |
14: 121,724,441 (GRCm39) |
S144P |
probably damaging |
Het |
| Slc6a7 |
A |
T |
18: 61,135,253 (GRCm39) |
V425E |
probably benign |
Het |
| Syt7 |
C |
T |
19: 10,416,576 (GRCm39) |
R253* |
probably null |
Het |
| Tm4sf1 |
A |
T |
3: 57,202,206 (GRCm39) |
C2S |
possibly damaging |
Het |
| Trio |
CCTTCTTCTTCT |
CCTTCTTCT |
15: 27,773,084 (GRCm39) |
|
probably benign |
Het |
| Trpm3 |
C |
T |
19: 22,879,506 (GRCm39) |
H594Y |
probably damaging |
Het |
| Tshz1 |
A |
T |
18: 84,033,207 (GRCm39) |
N400K |
probably damaging |
Het |
| Vat1 |
A |
T |
11: 101,351,441 (GRCm39) |
M300K |
probably benign |
Het |
| Vmn1r70 |
C |
A |
7: 10,367,556 (GRCm39) |
|
probably null |
Het |
| Vmn2r5 |
C |
T |
3: 64,411,339 (GRCm39) |
D410N |
probably damaging |
Het |
| Yap1 |
T |
C |
9: 7,934,682 (GRCm39) |
D428G |
probably damaging |
Het |
| Zbed6 |
A |
G |
1: 133,587,127 (GRCm39) |
I70T |
probably benign |
Het |
| Zfp157 |
A |
G |
5: 138,455,191 (GRCm39) |
Y463C |
probably damaging |
Het |
|
| Other mutations in Pnpla7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00421:Pnpla7
|
APN |
2 |
24,866,327 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00765:Pnpla7
|
APN |
2 |
24,870,236 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01576:Pnpla7
|
APN |
2 |
24,906,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01626:Pnpla7
|
APN |
2 |
24,940,905 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
IGL01844:Pnpla7
|
APN |
2 |
24,940,985 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02280:Pnpla7
|
APN |
2 |
24,901,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02629:Pnpla7
|
APN |
2 |
24,940,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02642:Pnpla7
|
APN |
2 |
24,940,288 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL02931:Pnpla7
|
APN |
2 |
24,905,241 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL03162:Pnpla7
|
APN |
2 |
24,905,301 (GRCm39) |
unclassified |
probably benign |
|
|
PIT4495001:Pnpla7
|
UTSW |
2 |
24,932,151 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0047:Pnpla7
|
UTSW |
2 |
24,901,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0047:Pnpla7
|
UTSW |
2 |
24,901,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0064:Pnpla7
|
UTSW |
2 |
24,887,239 (GRCm39) |
nonsense |
probably null |
|
|
R0064:Pnpla7
|
UTSW |
2 |
24,887,239 (GRCm39) |
nonsense |
probably null |
|
|
R0309:Pnpla7
|
UTSW |
2 |
24,877,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0541:Pnpla7
|
UTSW |
2 |
24,885,305 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0556:Pnpla7
|
UTSW |
2 |
24,942,313 (GRCm39) |
splice site |
probably null |
|
|
R0565:Pnpla7
|
UTSW |
2 |
24,870,129 (GRCm39) |
splice site |
probably benign |
|
|
R0830:Pnpla7
|
UTSW |
2 |
24,887,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0865:Pnpla7
|
UTSW |
2 |
24,872,135 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0893:Pnpla7
|
UTSW |
2 |
24,887,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0969:Pnpla7
|
UTSW |
2 |
24,940,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1102:Pnpla7
|
UTSW |
2 |
24,886,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1551:Pnpla7
|
UTSW |
2 |
24,937,720 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1572:Pnpla7
|
UTSW |
2 |
24,905,263 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1623:Pnpla7
|
UTSW |
2 |
24,942,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1876:Pnpla7
|
UTSW |
2 |
24,930,985 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1898:Pnpla7
|
UTSW |
2 |
24,943,796 (GRCm39) |
unclassified |
probably benign |
|
|
R1909:Pnpla7
|
UTSW |
2 |
24,887,300 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1973:Pnpla7
|
UTSW |
2 |
24,906,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2230:Pnpla7
|
UTSW |
2 |
24,941,610 (GRCm39) |
unclassified |
probably benign |
|
|
R2381:Pnpla7
|
UTSW |
2 |
24,870,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2655:Pnpla7
|
UTSW |
2 |
24,942,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3125:Pnpla7
|
UTSW |
2 |
24,932,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4223:Pnpla7
|
UTSW |
2 |
24,872,126 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4411:Pnpla7
|
UTSW |
2 |
24,941,716 (GRCm39) |
nonsense |
probably null |
|
|
R4674:Pnpla7
|
UTSW |
2 |
24,942,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4841:Pnpla7
|
UTSW |
2 |
24,870,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4842:Pnpla7
|
UTSW |
2 |
24,870,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4893:Pnpla7
|
UTSW |
2 |
24,943,688 (GRCm39) |
nonsense |
probably null |
|
|
R4941:Pnpla7
|
UTSW |
2 |
24,887,276 (GRCm39) |
splice site |
probably null |
|
|
R5116:Pnpla7
|
UTSW |
2 |
24,911,982 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5126:Pnpla7
|
UTSW |
2 |
24,870,056 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5138:Pnpla7
|
UTSW |
2 |
24,931,115 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5169:Pnpla7
|
UTSW |
2 |
24,940,321 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5188:Pnpla7
|
UTSW |
2 |
24,887,312 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5288:Pnpla7
|
UTSW |
2 |
24,931,031 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5307:Pnpla7
|
UTSW |
2 |
24,911,964 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5339:Pnpla7
|
UTSW |
2 |
24,892,949 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5384:Pnpla7
|
UTSW |
2 |
24,931,031 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5385:Pnpla7
|
UTSW |
2 |
24,931,031 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5479:Pnpla7
|
UTSW |
2 |
24,909,453 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5640:Pnpla7
|
UTSW |
2 |
24,893,013 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5662:Pnpla7
|
UTSW |
2 |
24,942,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5751:Pnpla7
|
UTSW |
2 |
24,871,790 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5874:Pnpla7
|
UTSW |
2 |
24,901,661 (GRCm39) |
missense |
probably benign |
|
|
R6284:Pnpla7
|
UTSW |
2 |
24,906,630 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6351:Pnpla7
|
UTSW |
2 |
24,901,576 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6513:Pnpla7
|
UTSW |
2 |
24,906,550 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7193:Pnpla7
|
UTSW |
2 |
24,941,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7503:Pnpla7
|
UTSW |
2 |
24,873,544 (GRCm39) |
nonsense |
probably null |
|
|
R7526:Pnpla7
|
UTSW |
2 |
24,888,678 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7791:Pnpla7
|
UTSW |
2 |
24,942,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pnpla7
|
UTSW |
2 |
24,873,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8283:Pnpla7
|
UTSW |
2 |
24,940,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8993:Pnpla7
|
UTSW |
2 |
24,943,431 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9086:Pnpla7
|
UTSW |
2 |
24,929,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9229:Pnpla7
|
UTSW |
2 |
24,873,503 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9494:Pnpla7
|
UTSW |
2 |
24,942,390 (GRCm39) |
nonsense |
probably null |
|
|
R9651:Pnpla7
|
UTSW |
2 |
24,892,931 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Pnpla7
|
UTSW |
2 |
24,888,771 (GRCm39) |
missense |
probably null |
0.06 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTTGAGGGTAAGAGGCCTG -3'
(R):5'- TTGGCATACTCCAAGGAAAACG -3'
Sequencing Primer
(F):5'- CCTGGTGGAGGTCTGCTAG -3'
(R):5'- GGCATACTCCAAGGAAAACGTGTAC -3'
|
| Posted On |
2015-09-24 |
Incidental Mutation