Incidental Mutation 'R4583:Chd6'
| ID |
343789 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd6
|
| Ensembl Gene |
ENSMUSG00000057133 |
| Gene Name |
chromodomain helicase DNA binding protein 6 |
| Synonyms |
5430439G14Rik, 6330406J24Rik |
| MMRRC Submission |
041804-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.755)
|
| Stock # |
R4583 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
160788898-160950995 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 160856114 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 715
(E715G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042291
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039782]
[ENSMUST00000134178]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039782
AA Change: E715G
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000042291
Gene: ENSMUSG00000057133
AA Change: E715G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
229 |
N/A |
INTRINSIC |
|
CHROMO
|
289 |
355 |
1.35e-4 |
SMART |
|
CHROMO
|
372 |
430 |
3.48e-7 |
SMART |
|
DEXDc
|
456 |
658 |
1.73e-39 |
SMART |
|
HELICc
|
812 |
896 |
3.84e-23 |
SMART |
|
low complexity region
|
1080 |
1094 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1108 |
1153 |
4e-23 |
BLAST |
|
SANT
|
1445 |
1504 |
1.51e0 |
SMART |
|
low complexity region
|
1866 |
1875 |
N/A |
INTRINSIC |
|
low complexity region
|
2048 |
2057 |
N/A |
INTRINSIC |
|
low complexity region
|
2130 |
2140 |
N/A |
INTRINSIC |
|
low complexity region
|
2277 |
2290 |
N/A |
INTRINSIC |
|
low complexity region
|
2333 |
2349 |
N/A |
INTRINSIC |
|
low complexity region
|
2437 |
2446 |
N/A |
INTRINSIC |
|
low complexity region
|
2539 |
2563 |
N/A |
INTRINSIC |
|
low complexity region
|
2652 |
2659 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000134178
AA Change: E714G
PolyPhen 2
Score 0.616 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000123240
Gene: ENSMUSG00000057133
AA Change: E714G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
228 |
N/A |
INTRINSIC |
|
CHROMO
|
288 |
354 |
1.35e-4 |
SMART |
|
CHROMO
|
371 |
429 |
3.48e-7 |
SMART |
|
DEXDc
|
455 |
657 |
1.73e-39 |
SMART |
|
HELICc
|
811 |
895 |
3.84e-23 |
SMART |
|
low complexity region
|
1079 |
1093 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1107 |
1152 |
4e-23 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137831
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000138078
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the chromodomain/helicase/DNA-binding domain family of chromatin remodeling enzymes. This protein has been found to be specifically involved in transcription initiation and elongation. Homozygous knockout mice exhibit impaired motor coordination. A pseudogene has been identified on chromosome 8. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 119 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022A10Rik |
T |
C |
7: 27,274,017 (GRCm39) |
L86P |
unknown |
Het |
| Aimp1 |
C |
T |
3: 132,382,808 (GRCm39) |
E23K |
probably damaging |
Het |
| Ap2b1 |
A |
T |
11: 83,288,605 (GRCm39) |
N884I |
probably benign |
Het |
| Apoe |
G |
T |
7: 19,431,423 (GRCm39) |
Q65K |
possibly damaging |
Het |
| Arhgef1 |
T |
A |
7: 24,611,996 (GRCm39) |
D93E |
probably benign |
Het |
| Arhgef12 |
G |
T |
9: 42,888,958 (GRCm39) |
T1085K |
probably damaging |
Het |
| Arid5a |
T |
C |
1: 36,356,745 (GRCm39) |
|
probably null |
Het |
| Atp9a |
A |
T |
2: 168,531,280 (GRCm39) |
|
probably null |
Het |
| Baz1a |
T |
C |
12: 54,969,325 (GRCm39) |
I635V |
probably damaging |
Het |
| Bbs10 |
A |
G |
10: 111,136,995 (GRCm39) |
K703E |
probably benign |
Het |
| Cckar |
T |
A |
5: 53,857,124 (GRCm39) |
M429L |
probably benign |
Het |
| Ccl3 |
A |
T |
11: 83,539,164 (GRCm39) |
L65Q |
probably benign |
Het |
| Ccr3 |
A |
G |
9: 123,829,477 (GRCm39) |
T271A |
probably benign |
Het |
| Cd8b1 |
T |
A |
6: 71,303,081 (GRCm39) |
I52N |
probably damaging |
Het |
| Cdh15 |
G |
A |
8: 123,591,767 (GRCm39) |
E551K |
probably damaging |
Het |
| Cdh17 |
A |
G |
4: 11,810,466 (GRCm39) |
K719R |
probably benign |
Het |
| Cfap43 |
T |
C |
19: 47,825,655 (GRCm39) |
R38G |
probably null |
Het |
| Cldn34b2 |
T |
A |
X: 153,908,625 (GRCm39) |
R68* |
probably null |
Het |
| Col19a1 |
T |
G |
1: 24,600,410 (GRCm39) |
D44A |
unknown |
Het |
| Colgalt2 |
C |
T |
1: 152,382,627 (GRCm39) |
S493F |
probably damaging |
Het |
| Cr1l |
T |
C |
1: 194,812,139 (GRCm39) |
I99M |
probably damaging |
Het |
| Crybg1 |
T |
C |
10: 43,873,616 (GRCm39) |
E1164G |
probably damaging |
Het |
| Cym |
G |
T |
3: 107,118,718 (GRCm39) |
D367E |
probably damaging |
Het |
| Dennd2a |
G |
T |
6: 39,499,776 (GRCm39) |
T263K |
probably damaging |
Het |
| Dhx9 |
T |
A |
1: 153,336,049 (GRCm39) |
M869L |
probably damaging |
Het |
| Dnm2 |
A |
G |
9: 21,415,742 (GRCm39) |
H692R |
probably damaging |
Het |
| Ern1 |
A |
T |
11: 106,298,031 (GRCm39) |
S697T |
probably damaging |
Het |
| F12 |
G |
A |
13: 55,568,943 (GRCm39) |
T273I |
probably benign |
Het |
| Fam151b |
A |
T |
13: 92,604,617 (GRCm39) |
L124Q |
probably damaging |
Het |
| Fancg |
A |
G |
4: 43,002,991 (GRCm39) |
V622A |
probably benign |
Het |
| Fbxo2 |
T |
A |
4: 148,249,356 (GRCm39) |
N159K |
possibly damaging |
Het |
| Fgd2 |
C |
A |
17: 29,586,052 (GRCm39) |
T212K |
possibly damaging |
Het |
| Fhl3 |
T |
A |
4: 124,601,342 (GRCm39) |
D178E |
probably benign |
Het |
| Filip1 |
G |
T |
9: 79,723,091 (GRCm39) |
A1176D |
possibly damaging |
Het |
| Fndc1 |
T |
C |
17: 7,958,081 (GRCm39) |
Y1722C |
probably damaging |
Het |
| Frem3 |
T |
C |
8: 81,340,143 (GRCm39) |
V812A |
probably benign |
Het |
| Fsip2 |
A |
G |
2: 82,809,017 (GRCm39) |
I1779V |
probably benign |
Het |
| Gli2 |
C |
T |
1: 118,769,798 (GRCm39) |
V585I |
probably benign |
Het |
| Gm15056 |
C |
G |
8: 21,390,697 (GRCm39) |
S80T |
probably benign |
Het |
| Gm5145 |
A |
G |
17: 20,790,715 (GRCm39) |
E31G |
probably benign |
Het |
| Gmfg |
A |
G |
7: 28,145,369 (GRCm39) |
Y71C |
probably damaging |
Het |
| Grk1 |
A |
G |
8: 13,459,322 (GRCm39) |
E291G |
probably damaging |
Het |
| Gtpbp1 |
A |
G |
15: 79,600,152 (GRCm39) |
E393G |
possibly damaging |
Het |
| Gtpbp2 |
A |
G |
17: 46,472,071 (GRCm39) |
D2G |
probably damaging |
Het |
| Hc |
A |
T |
2: 34,918,189 (GRCm39) |
V698E |
probably benign |
Het |
| Helz |
G |
A |
11: 107,536,895 (GRCm39) |
R249H |
probably damaging |
Het |
| Hmcn2 |
A |
G |
2: 31,303,277 (GRCm39) |
I2973V |
possibly damaging |
Het |
| Hnrnpa3 |
A |
G |
2: 75,493,950 (GRCm39) |
R286G |
probably benign |
Het |
| Hus1b |
A |
T |
13: 31,131,501 (GRCm39) |
W53R |
probably damaging |
Het |
| Hydin |
C |
T |
8: 111,321,857 (GRCm39) |
T4503I |
probably benign |
Het |
| Ighmbp2 |
G |
C |
19: 3,315,324 (GRCm39) |
P699A |
probably benign |
Het |
| Igkv1-122 |
A |
T |
6: 67,994,442 (GRCm39) |
Y110F |
probably benign |
Het |
| Igkv8-28 |
T |
C |
6: 70,120,604 (GRCm39) |
Y113C |
probably damaging |
Het |
| Iigp1c |
T |
C |
18: 60,379,152 (GRCm39) |
I229T |
possibly damaging |
Het |
| Il16 |
A |
G |
7: 83,332,107 (GRCm39) |
S158P |
probably damaging |
Het |
| Kalrn |
T |
A |
16: 34,055,637 (GRCm39) |
H876L |
probably damaging |
Het |
| Kdm5d |
T |
A |
Y: 914,134 (GRCm39) |
L357H |
probably damaging |
Het |
| Krt78 |
T |
C |
15: 101,855,055 (GRCm39) |
T919A |
possibly damaging |
Het |
| L3mbtl2 |
T |
C |
15: 81,569,107 (GRCm39) |
C594R |
probably damaging |
Het |
| Lcorl |
A |
T |
5: 45,890,931 (GRCm39) |
L474* |
probably null |
Het |
| Lgals3 |
A |
T |
14: 47,619,144 (GRCm39) |
|
probably null |
Het |
| Lnx1 |
C |
T |
5: 74,771,457 (GRCm39) |
V350I |
probably benign |
Het |
| Lpcat3 |
T |
G |
6: 124,680,286 (GRCm39) |
W429G |
possibly damaging |
Het |
| Lrp1 |
T |
C |
10: 127,377,241 (GRCm39) |
T4149A |
probably benign |
Het |
| Memo1 |
G |
A |
17: 74,565,456 (GRCm39) |
Q36* |
probably null |
Het |
| Mical2 |
A |
G |
7: 112,012,154 (GRCm39) |
N668S |
probably benign |
Het |
| Ms4a10 |
A |
T |
19: 10,945,553 (GRCm39) |
I76N |
possibly damaging |
Het |
| Mthfr |
T |
G |
4: 148,136,329 (GRCm39) |
L362V |
possibly damaging |
Het |
| Myh3 |
T |
A |
11: 66,987,279 (GRCm39) |
Y1376* |
probably null |
Het |
| Mymk |
C |
A |
2: 26,952,292 (GRCm39) |
V192F |
probably benign |
Het |
| Myo1c |
A |
G |
11: 75,562,688 (GRCm39) |
D966G |
possibly damaging |
Het |
| Ncam2 |
A |
G |
16: 81,314,445 (GRCm39) |
N474D |
probably damaging |
Het |
| Nmnat1 |
T |
C |
4: 149,553,608 (GRCm39) |
N168S |
possibly damaging |
Het |
| Nmur1 |
C |
T |
1: 86,314,367 (GRCm39) |
V323M |
possibly damaging |
Het |
| Npr2 |
C |
A |
4: 43,633,522 (GRCm39) |
|
probably null |
Het |
| Nsd3 |
T |
A |
8: 26,200,703 (GRCm39) |
M1265K |
probably benign |
Het |
| Or13c7 |
A |
G |
4: 43,855,262 (GRCm39) |
T318A |
probably benign |
Het |
| Or1e34 |
T |
C |
11: 73,778,629 (GRCm39) |
T190A |
probably damaging |
Het |
| Or1j16 |
A |
C |
2: 36,530,626 (GRCm39) |
T192P |
probably damaging |
Het |
| Or4c107 |
T |
A |
2: 88,789,556 (GRCm39) |
F249I |
probably damaging |
Het |
| Or4c11 |
G |
T |
2: 88,695,838 (GRCm39) |
M296I |
probably benign |
Het |
| Or5b108 |
T |
A |
19: 13,168,062 (GRCm39) |
F10L |
probably damaging |
Het |
| Or5i1 |
T |
C |
2: 87,613,565 (GRCm39) |
V227A |
possibly damaging |
Het |
| Or6c216 |
T |
C |
10: 129,678,344 (GRCm39) |
D189G |
probably damaging |
Het |
| Otub1 |
G |
A |
19: 7,181,801 (GRCm39) |
A25V |
possibly damaging |
Het |
| Paqr3 |
T |
A |
5: 97,256,069 (GRCm39) |
R102* |
probably null |
Het |
| Patl2 |
A |
G |
2: 121,957,226 (GRCm39) |
S103P |
probably benign |
Het |
| Pcdhb15 |
A |
T |
18: 37,608,628 (GRCm39) |
H620L |
possibly damaging |
Het |
| Pdgfc |
A |
T |
3: 81,048,835 (GRCm39) |
D81V |
possibly damaging |
Het |
| Pdia2 |
T |
C |
17: 26,415,476 (GRCm39) |
D447G |
probably damaging |
Het |
| Pold1 |
C |
A |
7: 44,188,337 (GRCm39) |
A514S |
probably damaging |
Het |
| Pomgnt1 |
C |
T |
4: 116,015,691 (GRCm39) |
T552I |
probably benign |
Het |
| Ppl |
T |
C |
16: 4,922,400 (GRCm39) |
E294G |
probably benign |
Het |
| Pramel12 |
A |
G |
4: 143,143,324 (GRCm39) |
Y30C |
probably damaging |
Het |
| Prkcb |
A |
G |
7: 122,056,447 (GRCm39) |
S100G |
probably benign |
Het |
| Psg16 |
T |
G |
7: 16,829,097 (GRCm39) |
I227S |
probably benign |
Het |
| Rbbp6 |
AAAGAAGAAGAAGAAGAAG |
AAAGAAGAAGAAGAAG |
7: 122,601,175 (GRCm39) |
|
probably benign |
Het |
| Reck |
T |
C |
4: 43,931,062 (GRCm39) |
|
probably null |
Het |
| Rrbp1 |
C |
T |
2: 143,830,671 (GRCm39) |
G499S |
probably benign |
Het |
| Sema6d |
G |
T |
2: 124,506,082 (GRCm39) |
R630L |
probably damaging |
Het |
| Slc29a1 |
A |
G |
17: 45,900,882 (GRCm39) |
V94A |
possibly damaging |
Het |
| Slc35a1 |
T |
A |
4: 34,664,146 (GRCm39) |
Q324L |
probably benign |
Het |
| Slc35c1 |
A |
T |
2: 92,289,266 (GRCm39) |
L80Q |
probably damaging |
Het |
| Slc7a10 |
G |
T |
7: 34,897,377 (GRCm39) |
|
probably null |
Het |
| Srrm2 |
C |
T |
17: 24,038,593 (GRCm39) |
|
probably benign |
Het |
| Stk38 |
T |
G |
17: 29,201,130 (GRCm39) |
D182A |
probably damaging |
Het |
| Tas2r104 |
C |
T |
6: 131,662,398 (GRCm39) |
G104S |
probably benign |
Het |
| Tmem121b |
T |
C |
6: 120,469,055 (GRCm39) |
E554G |
probably damaging |
Het |
| Tor1aip2 |
A |
G |
1: 155,940,888 (GRCm39) |
H398R |
probably benign |
Het |
| Tram2 |
C |
T |
1: 21,083,673 (GRCm39) |
V83I |
probably benign |
Het |
| Ube3a |
C |
T |
7: 58,935,811 (GRCm39) |
T565I |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,108,164 (GRCm39) |
V56A |
possibly damaging |
Het |
| Vmn1r128 |
T |
C |
7: 21,083,644 (GRCm39) |
V116A |
possibly damaging |
Het |
| Vmn1r170 |
C |
T |
7: 23,306,087 (GRCm39) |
T163I |
probably benign |
Het |
| Vmn2r75 |
T |
A |
7: 85,813,290 (GRCm39) |
D504V |
possibly damaging |
Het |
| Vps36 |
G |
A |
8: 22,708,436 (GRCm39) |
M363I |
probably benign |
Het |
| Wdsub1 |
A |
G |
2: 59,708,661 (GRCm39) |
S71P |
probably damaging |
Het |
| Zdhhc12 |
A |
G |
2: 29,981,496 (GRCm39) |
F189L |
probably benign |
Het |
| Zfp521 |
T |
C |
18: 13,977,387 (GRCm39) |
M1009V |
probably benign |
Het |
|
| Other mutations in Chd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00837:Chd6
|
APN |
2 |
160,883,999 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00899:Chd6
|
APN |
2 |
160,871,218 (GRCm39) |
splice site |
probably benign |
|
|
IGL01104:Chd6
|
APN |
2 |
160,803,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01295:Chd6
|
APN |
2 |
160,830,290 (GRCm39) |
splice site |
probably benign |
|
|
IGL01717:Chd6
|
APN |
2 |
160,807,179 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01795:Chd6
|
APN |
2 |
160,803,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01814:Chd6
|
APN |
2 |
160,901,849 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02016:Chd6
|
APN |
2 |
160,825,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Chd6
|
APN |
2 |
160,819,432 (GRCm39) |
missense |
probably benign |
|
|
IGL02158:Chd6
|
APN |
2 |
160,868,212 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02313:Chd6
|
APN |
2 |
160,807,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02472:Chd6
|
APN |
2 |
160,826,372 (GRCm39) |
splice site |
probably benign |
|
|
IGL02522:Chd6
|
APN |
2 |
160,807,716 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02626:Chd6
|
APN |
2 |
160,881,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02727:Chd6
|
APN |
2 |
160,811,383 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02738:Chd6
|
APN |
2 |
160,807,618 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL02743:Chd6
|
APN |
2 |
160,802,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02800:Chd6
|
APN |
2 |
160,826,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02811:Chd6
|
APN |
2 |
160,832,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02850:Chd6
|
APN |
2 |
160,861,536 (GRCm39) |
nonsense |
probably null |
|
|
IGL02979:Chd6
|
APN |
2 |
160,808,090 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02993:Chd6
|
APN |
2 |
160,894,304 (GRCm39) |
splice site |
probably benign |
|
|
IGL03277:Chd6
|
APN |
2 |
160,824,981 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03346:Chd6
|
APN |
2 |
160,802,282 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03357:Chd6
|
APN |
2 |
160,859,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL03134:Chd6
|
UTSW |
2 |
160,807,403 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0212:Chd6
|
UTSW |
2 |
160,894,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0363:Chd6
|
UTSW |
2 |
160,856,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0399:Chd6
|
UTSW |
2 |
160,894,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0511:Chd6
|
UTSW |
2 |
160,834,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0771:Chd6
|
UTSW |
2 |
160,861,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1184:Chd6
|
UTSW |
2 |
160,872,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1277:Chd6
|
UTSW |
2 |
160,809,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1396:Chd6
|
UTSW |
2 |
160,825,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1647:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1648:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:Chd6
|
UTSW |
2 |
160,823,587 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1766:Chd6
|
UTSW |
2 |
160,808,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1871:Chd6
|
UTSW |
2 |
160,832,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1928:Chd6
|
UTSW |
2 |
160,809,920 (GRCm39) |
splice site |
probably benign |
|
|
R1973:Chd6
|
UTSW |
2 |
160,808,307 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Chd6
|
UTSW |
2 |
160,825,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2340:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2341:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2519:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2919:Chd6
|
UTSW |
2 |
160,809,800 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3025:Chd6
|
UTSW |
2 |
160,808,472 (GRCm39) |
small deletion |
probably benign |
|
|
R3426:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3427:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4042:Chd6
|
UTSW |
2 |
160,830,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4273:Chd6
|
UTSW |
2 |
160,803,211 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4360:Chd6
|
UTSW |
2 |
160,791,776 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R4399:Chd6
|
UTSW |
2 |
160,807,238 (GRCm39) |
missense |
probably benign |
|
|
R4458:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4625:Chd6
|
UTSW |
2 |
160,811,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:Chd6
|
UTSW |
2 |
160,812,103 (GRCm39) |
missense |
probably benign |
|
|
R4765:Chd6
|
UTSW |
2 |
160,808,164 (GRCm39) |
nonsense |
probably null |
|
|
R4779:Chd6
|
UTSW |
2 |
160,791,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Chd6
|
UTSW |
2 |
160,871,219 (GRCm39) |
splice site |
probably benign |
|
|
R5068:Chd6
|
UTSW |
2 |
160,808,289 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5215:Chd6
|
UTSW |
2 |
160,791,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5275:Chd6
|
UTSW |
2 |
160,811,283 (GRCm39) |
missense |
probably benign |
|
|
R5405:Chd6
|
UTSW |
2 |
160,807,310 (GRCm39) |
missense |
probably benign |
|
|
R5598:Chd6
|
UTSW |
2 |
160,856,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5693:Chd6
|
UTSW |
2 |
160,807,185 (GRCm39) |
missense |
probably benign |
|
|
R5697:Chd6
|
UTSW |
2 |
160,859,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Chd6
|
UTSW |
2 |
160,791,798 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5759:Chd6
|
UTSW |
2 |
160,825,682 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5954:Chd6
|
UTSW |
2 |
160,807,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6025:Chd6
|
UTSW |
2 |
160,807,502 (GRCm39) |
missense |
probably benign |
|
|
R6104:Chd6
|
UTSW |
2 |
160,856,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Chd6
|
UTSW |
2 |
160,791,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6393:Chd6
|
UTSW |
2 |
160,821,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6452:Chd6
|
UTSW |
2 |
160,807,418 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6468:Chd6
|
UTSW |
2 |
160,854,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6784:Chd6
|
UTSW |
2 |
160,808,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6803:Chd6
|
UTSW |
2 |
160,802,279 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6869:Chd6
|
UTSW |
2 |
160,807,650 (GRCm39) |
missense |
probably benign |
|
|
R6895:Chd6
|
UTSW |
2 |
160,830,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Chd6
|
UTSW |
2 |
160,855,047 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7061:Chd6
|
UTSW |
2 |
160,867,885 (GRCm39) |
nonsense |
probably null |
|
|
R7064:Chd6
|
UTSW |
2 |
160,791,983 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Chd6
|
UTSW |
2 |
160,803,199 (GRCm39) |
nonsense |
probably null |
|
|
R7287:Chd6
|
UTSW |
2 |
160,850,312 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7431:Chd6
|
UTSW |
2 |
160,868,248 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7486:Chd6
|
UTSW |
2 |
160,791,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7509:Chd6
|
UTSW |
2 |
160,855,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7699:Chd6
|
UTSW |
2 |
160,867,863 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7748:Chd6
|
UTSW |
2 |
160,808,539 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7785:Chd6
|
UTSW |
2 |
160,812,095 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8002:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Chd6
|
UTSW |
2 |
160,799,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8317:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8388:Chd6
|
UTSW |
2 |
160,861,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8865:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8867:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8996:Chd6
|
UTSW |
2 |
160,823,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9270:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9310:Chd6
|
UTSW |
2 |
160,881,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9367:Chd6
|
UTSW |
2 |
160,871,784 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9438:Chd6
|
UTSW |
2 |
160,799,078 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9756:Chd6
|
UTSW |
2 |
160,802,259 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Chd6
|
UTSW |
2 |
160,808,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATCAACCTCTCTGAAGCTCTG -3'
(R):5'- TGGGGCAAATAAATGGCTTTCC -3'
Sequencing Primer
(F):5'- GCAAACAGGCCTTTCTTATTACTAGC -3'
(R):5'- GGGGCAAATAAATGGCTTTCCTTTTC -3'
|
| Posted On |
2015-09-24 |
Incidental Mutation