Incidental Mutation 'R0254:Clip1'
| ID |
34548 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Rsn, CLIP-170, 4631429H07Rik, restin, Clip 170, 1110007I12Rik, Clip50, cytoplasmic linker protein 50 |
| MMRRC Submission |
038485-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0254 (G1)
|
| Quality Score |
94 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
123715857-123822527 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to T
at 123755395 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
[ENSMUST00000149410]
|
| AlphaFold |
Q922J3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000031382
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063905
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111561
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111564
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111566
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133545
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137363
|
| SMART Domains |
Protein: ENSMUSP00000121425
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
2 |
31 |
2.59e0 |
SMART |
|
low complexity region
|
39 |
57 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
84 |
N/A |
INTRINSIC |
|
coiled coil region
|
101 |
276 |
N/A |
INTRINSIC |
|
coiled coil region
|
322 |
361 |
N/A |
INTRINSIC |
|
coiled coil region
|
393 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1002 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1004 |
1021 |
4.2e-9 |
PFAM |
|
ZnF_C2HC
|
1046 |
1062 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154672
|
| SMART Domains |
Protein: ENSMUSP00000122064
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
43 |
59 |
N/A |
INTRINSIC |
|
low complexity region
|
165 |
176 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
352 |
375 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
358 |
377 |
5.32e-6 |
PROSPERO |
|
internal_repeat_1
|
450 |
473 |
1.56e-8 |
PROSPERO |
|
internal_repeat_3
|
544 |
563 |
5.32e-6 |
PROSPERO |
|
internal_repeat_2
|
553 |
575 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
735 |
744 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
781 |
803 |
2.88e-7 |
PROSPERO |
|
low complexity region
|
819 |
830 |
N/A |
INTRINSIC |
|
low complexity region
|
962 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1081 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1121 |
N/A |
INTRINSIC |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149410
|
| SMART Domains |
Protein: ENSMUSP00000115965
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
32 |
N/A |
INTRINSIC |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
334 |
458 |
N/A |
INTRINSIC |
|
coiled coil region
|
504 |
543 |
N/A |
INTRINSIC |
|
coiled coil region
|
575 |
827 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144121
|
| SMART Domains |
Protein: ENSMUSP00000119641
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
37 |
102 |
1.05e-31 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.1%
- 20x: 91.7%
|
| Validation Efficiency |
100% (100/100) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700034J05Rik |
T |
A |
6: 146,853,902 (GRCm39) |
M252L |
probably benign |
Het |
| Abca6 |
A |
G |
11: 110,127,615 (GRCm39) |
V314A |
probably benign |
Het |
| Abcb1b |
A |
T |
5: 8,877,409 (GRCm39) |
E656D |
probably benign |
Het |
| Abhd4 |
T |
C |
14: 54,500,691 (GRCm39) |
I160T |
probably benign |
Het |
| Aco2 |
T |
C |
15: 81,773,557 (GRCm39) |
V32A |
probably damaging |
Het |
| Actl6b |
A |
G |
5: 137,552,406 (GRCm39) |
|
probably benign |
Het |
| Akap13 |
T |
C |
7: 75,386,352 (GRCm39) |
|
probably benign |
Het |
| Alpk3 |
A |
T |
7: 80,726,722 (GRCm39) |
T136S |
probably benign |
Het |
| Ap1g1 |
G |
T |
8: 110,529,749 (GRCm39) |
M56I |
probably benign |
Het |
| Arid2 |
C |
T |
15: 96,268,452 (GRCm39) |
T855I |
probably damaging |
Het |
| Asprv1 |
T |
C |
6: 86,606,077 (GRCm39) |
F308L |
probably damaging |
Het |
| Ass1 |
A |
T |
2: 31,404,831 (GRCm39) |
N371Y |
probably damaging |
Het |
| Atp11b |
T |
A |
3: 35,866,259 (GRCm39) |
M378K |
possibly damaging |
Het |
| Atp1a3 |
T |
C |
7: 24,680,937 (GRCm39) |
|
probably benign |
Het |
| Blk |
C |
A |
14: 63,618,253 (GRCm39) |
A218S |
probably benign |
Het |
| C4b |
T |
A |
17: 34,953,750 (GRCm39) |
T953S |
probably benign |
Het |
| Cdadc1 |
T |
C |
14: 59,813,356 (GRCm39) |
|
probably benign |
Het |
| Cdca2 |
C |
A |
14: 67,914,627 (GRCm39) |
L877F |
probably damaging |
Het |
| Ceacam10 |
G |
T |
7: 24,477,733 (GRCm39) |
V83L |
probably damaging |
Het |
| Cep290 |
A |
T |
10: 100,350,436 (GRCm39) |
I677F |
probably benign |
Het |
| Col11a2 |
G |
T |
17: 34,283,777 (GRCm39) |
|
probably benign |
Het |
| Coro1c |
A |
T |
5: 113,983,313 (GRCm39) |
V405D |
probably benign |
Het |
| Crebrf |
A |
G |
17: 26,958,568 (GRCm39) |
T13A |
probably benign |
Het |
| Cspg4 |
A |
G |
9: 56,804,694 (GRCm39) |
E1835G |
probably damaging |
Het |
| Cubn |
A |
T |
2: 13,480,846 (GRCm39) |
|
probably null |
Het |
| Cubn |
T |
C |
2: 13,429,505 (GRCm39) |
N1332S |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,445,325 (GRCm39) |
T1014A |
possibly damaging |
Het |
| Efnb1 |
T |
C |
X: 98,180,634 (GRCm39) |
|
probably benign |
Het |
| Elf2 |
G |
T |
3: 51,215,611 (GRCm39) |
P33Q |
probably damaging |
Het |
| Fap |
C |
T |
2: 62,333,746 (GRCm39) |
G633D |
probably damaging |
Het |
| Gm10288 |
T |
C |
3: 146,544,675 (GRCm39) |
|
noncoding transcript |
Het |
| Got2 |
T |
C |
8: 96,596,166 (GRCm39) |
N318S |
probably benign |
Het |
| Guk1 |
A |
T |
11: 59,076,854 (GRCm39) |
F76L |
probably damaging |
Het |
| H2-K2 |
A |
T |
17: 34,215,639 (GRCm39) |
|
probably benign |
Het |
| Helz2 |
C |
A |
2: 180,874,552 (GRCm39) |
G1981C |
probably damaging |
Het |
| Hinfp |
G |
A |
9: 44,209,536 (GRCm39) |
H250Y |
probably damaging |
Het |
| Hnrnpm |
C |
T |
17: 33,871,242 (GRCm39) |
|
probably null |
Het |
| Hsd11b2 |
T |
A |
8: 106,249,699 (GRCm39) |
V270E |
possibly damaging |
Het |
| Igbp1b |
A |
T |
6: 138,635,201 (GRCm39) |
M81K |
probably damaging |
Het |
| Kif11 |
A |
G |
19: 37,399,957 (GRCm39) |
T815A |
probably benign |
Het |
| Kit |
G |
A |
5: 75,781,581 (GRCm39) |
V337I |
probably benign |
Het |
| Klf11 |
T |
C |
12: 24,703,582 (GRCm39) |
S6P |
probably damaging |
Het |
| Klk13 |
T |
C |
7: 43,373,245 (GRCm39) |
V193A |
probably benign |
Het |
| Krt73 |
T |
A |
15: 101,708,324 (GRCm39) |
|
probably benign |
Het |
| L1td1 |
T |
A |
4: 98,625,419 (GRCm39) |
L538* |
probably null |
Het |
| Macf1 |
A |
G |
4: 123,326,572 (GRCm39) |
L2061P |
probably damaging |
Het |
| Mcm2 |
A |
G |
6: 88,860,998 (GRCm39) |
I900T |
probably damaging |
Het |
| Med16 |
A |
T |
10: 79,736,034 (GRCm39) |
N371K |
possibly damaging |
Het |
| Mepce |
A |
C |
5: 137,783,698 (GRCm39) |
D209E |
possibly damaging |
Het |
| Mrc2 |
C |
G |
11: 105,238,692 (GRCm39) |
P1249R |
probably benign |
Het |
| Mx2 |
A |
T |
16: 97,357,295 (GRCm39) |
I463L |
probably benign |
Het |
| Naaa |
A |
T |
5: 92,412,994 (GRCm39) |
N73K |
probably damaging |
Het |
| Nags |
T |
A |
11: 102,038,771 (GRCm39) |
L404Q |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,133,402 (GRCm39) |
Y3379H |
probably damaging |
Het |
| Nhsl1 |
A |
G |
10: 18,348,733 (GRCm39) |
E120G |
probably damaging |
Het |
| Or11j4 |
T |
C |
14: 50,630,536 (GRCm39) |
S108P |
probably damaging |
Het |
| Or4f53 |
A |
C |
2: 111,087,466 (GRCm39) |
N2T |
probably benign |
Het |
| Or51a42 |
T |
C |
7: 103,708,728 (GRCm39) |
H27R |
probably benign |
Het |
| Or51ah3 |
T |
A |
7: 103,209,829 (GRCm39) |
Y48* |
probably null |
Het |
| Or51f5 |
C |
A |
7: 102,424,076 (GRCm39) |
S115* |
probably null |
Het |
| Pcnt |
A |
G |
10: 76,228,414 (GRCm39) |
F1584L |
probably benign |
Het |
| Pdgfra |
G |
A |
5: 75,328,596 (GRCm39) |
V243I |
probably damaging |
Het |
| Polr2a |
T |
C |
11: 69,634,497 (GRCm39) |
I689V |
possibly damaging |
Het |
| Ppfia4 |
C |
A |
1: 134,251,962 (GRCm39) |
|
probably benign |
Het |
| Prmt8 |
C |
A |
6: 127,688,771 (GRCm39) |
V200L |
probably damaging |
Het |
| Prpf8 |
T |
A |
11: 75,397,188 (GRCm39) |
I2007N |
possibly damaging |
Het |
| Ptpn6 |
T |
C |
6: 124,705,113 (GRCm39) |
E230G |
probably damaging |
Het |
| R3hcc1l |
G |
A |
19: 42,551,587 (GRCm39) |
V195I |
probably damaging |
Het |
| Rb1cc1 |
C |
T |
1: 6,333,071 (GRCm39) |
T1330I |
probably damaging |
Het |
| Reep3 |
G |
T |
10: 66,857,575 (GRCm39) |
T172N |
probably benign |
Het |
| Rfwd3 |
A |
G |
8: 112,020,655 (GRCm39) |
V236A |
probably benign |
Het |
| Rgs22 |
T |
C |
15: 36,104,698 (GRCm39) |
I121V |
probably damaging |
Het |
| Robo1 |
T |
A |
16: 72,461,058 (GRCm39) |
F11I |
probably benign |
Het |
| Rsrc2 |
A |
G |
5: 123,878,910 (GRCm39) |
|
probably benign |
Het |
| Rubcn |
A |
G |
16: 32,668,316 (GRCm39) |
V117A |
probably benign |
Het |
| Scamp1 |
T |
G |
13: 94,347,088 (GRCm39) |
N192T |
probably benign |
Het |
| Scn8a |
T |
A |
15: 100,916,245 (GRCm39) |
I1218N |
probably damaging |
Het |
| Serinc1 |
A |
G |
10: 57,399,304 (GRCm39) |
S200P |
probably damaging |
Het |
| Serpinb9f |
T |
A |
13: 33,518,574 (GRCm39) |
F358Y |
probably damaging |
Het |
| Slc12a5 |
T |
C |
2: 164,839,165 (GRCm39) |
|
probably null |
Het |
| Slc5a4b |
T |
C |
10: 75,906,462 (GRCm39) |
M386V |
possibly damaging |
Het |
| Smarca5 |
A |
G |
8: 81,431,329 (GRCm39) |
F963L |
probably benign |
Het |
| Smchd1 |
A |
T |
17: 71,718,886 (GRCm39) |
F828I |
probably benign |
Het |
| Smr2l |
A |
T |
5: 88,430,230 (GRCm39) |
H42L |
possibly damaging |
Het |
| Stab2 |
G |
T |
10: 86,733,824 (GRCm39) |
Q1333K |
probably benign |
Het |
| Svop |
T |
C |
5: 114,176,600 (GRCm39) |
S349G |
probably benign |
Het |
| Tdrd1 |
G |
A |
19: 56,830,998 (GRCm39) |
S271N |
probably benign |
Het |
| Tec |
G |
A |
5: 72,941,081 (GRCm39) |
P159S |
probably benign |
Het |
| Tec |
T |
C |
5: 72,920,899 (GRCm39) |
|
probably benign |
Het |
| Tfip11 |
G |
A |
5: 112,483,521 (GRCm39) |
M645I |
probably benign |
Het |
| Thap12 |
A |
T |
7: 98,364,488 (GRCm39) |
T219S |
probably benign |
Het |
| Tmem87a |
C |
T |
2: 120,205,988 (GRCm39) |
R329H |
probably damaging |
Het |
| Tpsab1 |
A |
G |
17: 25,562,719 (GRCm39) |
Y227H |
probably damaging |
Het |
| Urah |
G |
A |
7: 140,417,602 (GRCm39) |
V114I |
probably benign |
Het |
| Wnt5a |
G |
A |
14: 28,244,811 (GRCm39) |
E353K |
probably damaging |
Het |
| Zfp1004 |
G |
A |
2: 150,033,784 (GRCm39) |
R35K |
possibly damaging |
Het |
| Zfp101 |
A |
T |
17: 33,599,952 (GRCm39) |
H601Q |
possibly damaging |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,768,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,717,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,755,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,721,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,741,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,761,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,755,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,759,857 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,759,919 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,791,633 (GRCm39) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,721,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,769,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4812001:Clip1
|
UTSW |
5 |
123,768,738 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0401:Clip1
|
UTSW |
5 |
123,791,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,778,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,717,554 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,785,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Clip1
|
UTSW |
5 |
123,768,466 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1700:Clip1
|
UTSW |
5 |
123,768,433 (GRCm39) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,791,559 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,761,281 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,741,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,728,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,755,892 (GRCm39) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,717,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,769,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,721,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,768,408 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4960:Clip1
|
UTSW |
5 |
123,792,066 (GRCm39) |
nonsense |
probably null |
|
|
R5014:Clip1
|
UTSW |
5 |
123,755,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,768,770 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,768,744 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,751,147 (GRCm39) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,768,303 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,751,366 (GRCm39) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,753,217 (GRCm39) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,765,460 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,753,152 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,751,604 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,751,897 (GRCm39) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,780,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6377:Clip1
|
UTSW |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6436:Clip1
|
UTSW |
5 |
123,779,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,778,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,752,827 (GRCm39) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,751,675 (GRCm39) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,761,333 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,791,673 (GRCm39) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,749,904 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,749,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,751,328 (GRCm39) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,741,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,751,857 (GRCm39) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,765,419 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7447:Clip1
|
UTSW |
5 |
123,791,696 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7458:Clip1
|
UTSW |
5 |
123,778,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,755,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,721,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,752,342 (GRCm39) |
missense |
|
|
|
R7831:Clip1
|
UTSW |
5 |
123,751,342 (GRCm39) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,760,861 (GRCm39) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,751,699 (GRCm39) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,768,782 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,785,981 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,780,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,794,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,752,770 (GRCm39) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,791,969 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,752,756 (GRCm39) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,752,645 (GRCm39) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,753,223 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,721,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,717,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,784,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,751,186 (GRCm39) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,760,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,755,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCTACTGCAAGCAAGCAGACAGAG -3'
(R):5'- CCAGTGTCAGGACCTGAAAGCTAAG -3'
Sequencing Primer
(F):5'- TGATGGCTACACAGGACATTTG -3'
(R):5'- GCTAAGTATGAAAAAGCCAGTTCTG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation