Incidental Mutation 'R0255:Anapc1'
| ID |
34632 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| MMRRC Submission |
038486-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0255 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 128476631 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 1329
(M1329K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000014499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
|
| AlphaFold |
P53995 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000014499
AA Change: M1329K
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: M1329K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154320
|
| Meta Mutation Damage Score |
0.4220 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.6%
|
| Validation Efficiency |
93% (102/110) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700113H08Rik |
T |
C |
10: 87,061,907 (GRCm39) |
F119S |
probably damaging |
Het |
| Abca13 |
C |
A |
11: 9,531,545 (GRCm39) |
Q4591K |
probably damaging |
Het |
| Aoah |
A |
T |
13: 21,163,710 (GRCm39) |
K338* |
probably null |
Het |
| Ascc3 |
A |
T |
10: 50,521,154 (GRCm39) |
T416S |
probably benign |
Het |
| Baz2a |
A |
G |
10: 127,950,508 (GRCm39) |
T484A |
possibly damaging |
Het |
| Btnl6 |
T |
C |
17: 34,727,477 (GRCm39) |
N351S |
probably benign |
Het |
| Cacna1s |
T |
G |
1: 136,046,544 (GRCm39) |
I1772S |
possibly damaging |
Het |
| Ccdc8 |
A |
G |
7: 16,729,582 (GRCm39) |
D357G |
unknown |
Het |
| Ccna1 |
T |
C |
3: 54,958,049 (GRCm39) |
E152G |
probably damaging |
Het |
| Cct4 |
A |
G |
11: 22,949,073 (GRCm39) |
D273G |
probably damaging |
Het |
| Cd9 |
A |
G |
6: 125,440,703 (GRCm39) |
V96A |
probably damaging |
Het |
| Cdc5l |
G |
A |
17: 45,726,610 (GRCm39) |
R321W |
probably damaging |
Het |
| Cdh20 |
T |
C |
1: 109,922,036 (GRCm39) |
S43P |
probably benign |
Het |
| Cep95 |
G |
A |
11: 106,702,097 (GRCm39) |
V365M |
probably benign |
Het |
| Ces1c |
T |
C |
8: 93,854,152 (GRCm39) |
T128A |
probably benign |
Het |
| Chil5 |
A |
G |
3: 105,926,583 (GRCm39) |
V82A |
probably damaging |
Het |
| Clmn |
T |
C |
12: 104,748,023 (GRCm39) |
D508G |
probably benign |
Het |
| Cog8 |
A |
T |
8: 107,775,777 (GRCm39) |
|
probably benign |
Het |
| Cst3 |
A |
T |
2: 148,717,089 (GRCm39) |
V70E |
probably damaging |
Het |
| Ctcf |
A |
G |
8: 106,390,671 (GRCm39) |
T93A |
possibly damaging |
Het |
| Ctsk |
C |
A |
3: 95,416,188 (GRCm39) |
N315K |
probably benign |
Het |
| Cyp2j12 |
G |
T |
4: 96,029,262 (GRCm39) |
D6E |
probably benign |
Het |
| Dhx34 |
A |
G |
7: 15,939,917 (GRCm39) |
V655A |
probably benign |
Het |
| Dock10 |
T |
C |
1: 80,583,593 (GRCm39) |
Y203C |
probably damaging |
Het |
| Dok7 |
A |
T |
5: 35,221,678 (GRCm39) |
D26V |
probably damaging |
Het |
| Epha8 |
G |
A |
4: 136,667,597 (GRCm39) |
H295Y |
probably damaging |
Het |
| Esf1 |
A |
G |
2: 139,990,843 (GRCm39) |
|
probably benign |
Het |
| Fam83c |
A |
G |
2: 155,671,672 (GRCm39) |
S588P |
probably benign |
Het |
| Fat3 |
G |
A |
9: 15,881,002 (GRCm39) |
|
probably benign |
Het |
| Fhdc1 |
T |
C |
3: 84,360,817 (GRCm39) |
|
probably benign |
Het |
| Frmd4b |
A |
G |
6: 97,285,047 (GRCm39) |
V338A |
probably damaging |
Het |
| Fsd1l |
A |
G |
4: 53,694,727 (GRCm39) |
T394A |
probably damaging |
Het |
| Gbf1 |
A |
G |
19: 46,242,549 (GRCm39) |
|
probably benign |
Het |
| Glg1 |
G |
T |
8: 111,886,490 (GRCm39) |
Q1101K |
possibly damaging |
Het |
| Glt8d2 |
T |
A |
10: 82,487,361 (GRCm39) |
|
probably null |
Het |
| Gm19345 |
T |
C |
7: 19,588,855 (GRCm39) |
|
probably benign |
Het |
| Gpr179 |
A |
T |
11: 97,226,892 (GRCm39) |
D1754E |
probably benign |
Het |
| Hydin |
A |
G |
8: 111,291,650 (GRCm39) |
T3381A |
probably benign |
Het |
| Igkv12-41 |
G |
A |
6: 69,835,822 (GRCm39) |
T16I |
possibly damaging |
Het |
| Insl5 |
A |
G |
4: 102,875,313 (GRCm39) |
*146Q |
probably null |
Het |
| Iqce |
A |
T |
5: 140,651,957 (GRCm39) |
I655N |
possibly damaging |
Het |
| Irf2bp1 |
G |
A |
7: 18,738,927 (GRCm39) |
R189H |
possibly damaging |
Het |
| Itprid2 |
T |
A |
2: 79,490,810 (GRCm39) |
L976Q |
probably damaging |
Het |
| Itsn1 |
C |
T |
16: 91,602,978 (GRCm39) |
|
probably benign |
Het |
| Kansl3 |
A |
T |
1: 36,384,050 (GRCm39) |
I724N |
probably benign |
Het |
| Kcna4 |
T |
C |
2: 107,126,907 (GRCm39) |
I547T |
probably damaging |
Het |
| Klk1b4 |
A |
T |
7: 43,860,158 (GRCm39) |
I91F |
probably benign |
Het |
| Lmbr1 |
A |
G |
5: 29,457,753 (GRCm39) |
S282P |
probably damaging |
Het |
| Lrrc17 |
G |
A |
5: 21,765,967 (GRCm39) |
A150T |
probably benign |
Het |
| Lrrc2 |
A |
G |
9: 110,809,966 (GRCm39) |
E334G |
possibly damaging |
Het |
| Lrrc7 |
G |
A |
3: 157,866,475 (GRCm39) |
Q1077* |
probably null |
Het |
| Mapk8 |
A |
T |
14: 33,109,264 (GRCm39) |
|
probably benign |
Het |
| Mast1 |
T |
A |
8: 85,638,650 (GRCm39) |
T1560S |
probably benign |
Het |
| Mdh1b |
C |
A |
1: 63,758,777 (GRCm39) |
A272S |
probably damaging |
Het |
| Myo15b |
T |
C |
11: 115,777,109 (GRCm39) |
Y912H |
probably damaging |
Het |
| Nf1 |
T |
G |
11: 79,299,525 (GRCm39) |
|
probably null |
Het |
| Nme7 |
T |
A |
1: 164,172,944 (GRCm39) |
D218E |
probably damaging |
Het |
| Nsun7 |
T |
A |
5: 66,446,751 (GRCm39) |
|
probably benign |
Het |
| Nxpe2 |
A |
G |
9: 48,251,870 (GRCm39) |
|
probably null |
Het |
| Or1e34 |
A |
G |
11: 73,778,655 (GRCm39) |
V181A |
probably benign |
Het |
| Or2ag16 |
G |
A |
7: 106,352,196 (GRCm39) |
T133I |
probably benign |
Het |
| Or2n1c |
T |
G |
17: 38,519,286 (GRCm39) |
I50R |
probably benign |
Het |
| Or5p53 |
T |
A |
7: 107,533,375 (GRCm39) |
V216D |
probably damaging |
Het |
| P2ry1 |
T |
C |
3: 60,910,951 (GRCm39) |
V30A |
probably benign |
Het |
| Pgm2 |
T |
A |
5: 64,269,386 (GRCm39) |
I491N |
possibly damaging |
Het |
| Pkd1l3 |
A |
T |
8: 110,365,386 (GRCm39) |
D1169V |
probably damaging |
Het |
| Poldip2 |
T |
A |
11: 78,403,189 (GRCm39) |
S18T |
probably benign |
Het |
| Prg4 |
C |
T |
1: 150,331,558 (GRCm39) |
|
probably benign |
Het |
| Prkab2 |
T |
A |
3: 97,574,728 (GRCm39) |
Y241* |
probably null |
Het |
| Prmt7 |
A |
G |
8: 106,953,839 (GRCm39) |
|
probably benign |
Het |
| Proser3 |
T |
A |
7: 30,245,842 (GRCm39) |
R80W |
probably damaging |
Het |
| Prr12 |
A |
G |
7: 44,699,415 (GRCm39) |
|
probably benign |
Het |
| Psmd1 |
A |
T |
1: 86,006,304 (GRCm39) |
L223F |
probably damaging |
Het |
| Rab13 |
A |
G |
3: 90,131,088 (GRCm39) |
|
probably benign |
Het |
| Rgl1 |
C |
T |
1: 152,428,347 (GRCm39) |
C294Y |
probably damaging |
Het |
| Rpl21-ps4 |
C |
A |
14: 11,227,556 (GRCm38) |
|
noncoding transcript |
Het |
| Rusc2 |
T |
C |
4: 43,423,954 (GRCm39) |
V1036A |
probably damaging |
Het |
| Sae1 |
T |
A |
7: 16,104,247 (GRCm39) |
K121* |
probably null |
Het |
| Sap130 |
C |
T |
18: 31,813,559 (GRCm39) |
P539S |
probably damaging |
Het |
| Saxo4 |
C |
T |
19: 10,452,418 (GRCm39) |
R364Q |
probably damaging |
Het |
| Scube2 |
A |
G |
7: 109,424,079 (GRCm39) |
L475P |
probably damaging |
Het |
| Sec16a |
T |
C |
2: 26,321,198 (GRCm39) |
D1298G |
probably damaging |
Het |
| Serpinb9b |
T |
C |
13: 33,222,003 (GRCm39) |
F206L |
probably benign |
Het |
| Sh3bp1 |
T |
A |
15: 78,788,534 (GRCm39) |
Y202* |
probably null |
Het |
| Shprh |
T |
A |
10: 11,062,135 (GRCm39) |
C1177S |
possibly damaging |
Het |
| Slc27a6 |
T |
C |
18: 58,742,937 (GRCm39) |
Y542H |
possibly damaging |
Het |
| Slc41a1 |
T |
C |
1: 131,771,650 (GRCm39) |
|
probably benign |
Het |
| Slc46a1 |
T |
C |
11: 78,361,625 (GRCm39) |
F424L |
probably damaging |
Het |
| Slc66a2 |
C |
T |
18: 80,306,733 (GRCm39) |
A101V |
probably benign |
Het |
| Slc6a12 |
G |
A |
6: 121,333,877 (GRCm39) |
V238I |
probably damaging |
Het |
| Slc6a20a |
A |
G |
9: 123,493,686 (GRCm39) |
V65A |
probably damaging |
Het |
| Slc9c1 |
T |
A |
16: 45,374,663 (GRCm39) |
S343T |
probably benign |
Het |
| Spcs3 |
C |
A |
8: 54,981,415 (GRCm39) |
R60I |
probably benign |
Het |
| Tbc1d16 |
C |
A |
11: 119,038,401 (GRCm39) |
R764L |
possibly damaging |
Het |
| Tcaf2 |
A |
T |
6: 42,619,838 (GRCm39) |
V63E |
possibly damaging |
Het |
| Tmc1 |
G |
T |
19: 20,766,951 (GRCm39) |
A750E |
possibly damaging |
Het |
| Tmem273 |
A |
G |
14: 32,530,320 (GRCm39) |
K83E |
possibly damaging |
Het |
| Tmem81 |
C |
G |
1: 132,435,567 (GRCm39) |
I124M |
probably damaging |
Het |
| Tmx3 |
T |
C |
18: 90,558,130 (GRCm39) |
I394T |
probably damaging |
Het |
| Trank1 |
G |
A |
9: 111,195,092 (GRCm39) |
E1039K |
possibly damaging |
Het |
| Trpc4ap |
A |
G |
2: 155,499,866 (GRCm39) |
|
probably benign |
Het |
| Tsen54 |
T |
C |
11: 115,706,234 (GRCm39) |
C123R |
probably damaging |
Het |
| Ubtd1 |
A |
G |
19: 42,020,373 (GRCm39) |
D39G |
possibly damaging |
Het |
| Vmn1r181 |
A |
T |
7: 23,683,759 (GRCm39) |
M75L |
probably benign |
Het |
| Zc3h7a |
T |
C |
16: 10,958,601 (GRCm39) |
T847A |
probably damaging |
Het |
| Zc3hav1 |
A |
G |
6: 38,313,485 (GRCm39) |
C187R |
probably damaging |
Het |
| Zfp692 |
G |
A |
11: 58,201,229 (GRCm39) |
|
probably benign |
Het |
| Zmiz1 |
G |
A |
14: 25,654,919 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0514:Anapc1
|
UTSW |
2 |
128,474,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Anapc1
|
UTSW |
2 |
128,470,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1677:Anapc1
|
UTSW |
2 |
128,518,128 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1854:Anapc1
|
UTSW |
2 |
128,517,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4824:Anapc1
|
UTSW |
2 |
128,470,610 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4960:Anapc1
|
UTSW |
2 |
128,526,514 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9516:Anapc1
|
UTSW |
2 |
128,517,633 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTAGATCATAGCCAACGCCAGAGTAG -3'
(R):5'- GGACAAATAGGGCTTCTGAGTTGAGTG -3'
Sequencing Primer
(F):5'- GGACAAGTCACATCCACGTTTATG -3'
(R):5'- CTGGTGCAGTAATGAAAGTACTC -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation