Incidental Mutation 'R4676:Plxnb1'
| ID |
349584 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| MMRRC Submission |
042013-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4676 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 108939503 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glutamine
at position 1416
(R1416Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000072093
AA Change: R1416Q
PolyPhen 2
Score 0.631 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: R1416Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192117
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192988
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194734
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195364
|
| Meta Mutation Damage Score |
0.1185 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.8%
|
| Validation Efficiency |
98% (93/95) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3110009E18Rik |
T |
A |
1: 120,078,382 (GRCm39) |
I13N |
probably damaging |
Het |
| Abcd3 |
T |
A |
3: 121,567,815 (GRCm39) |
T409S |
possibly damaging |
Het |
| Acad12 |
C |
A |
5: 121,745,234 (GRCm39) |
W317L |
probably damaging |
Het |
| Acap1 |
T |
A |
11: 69,780,294 (GRCm39) |
M50L |
probably benign |
Het |
| Acvr1b |
T |
A |
15: 101,100,867 (GRCm39) |
V343E |
probably damaging |
Het |
| Adgb |
C |
A |
10: 10,302,454 (GRCm39) |
G371W |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,082,774 (GRCm39) |
K1966R |
probably damaging |
Het |
| Akap9 |
C |
T |
5: 4,114,515 (GRCm39) |
Q48* |
probably null |
Het |
| Ano10 |
T |
C |
9: 122,092,853 (GRCm39) |
R159G |
probably damaging |
Het |
| Anxa7 |
T |
C |
14: 20,517,983 (GRCm39) |
M128V |
probably benign |
Het |
| Arhgef40 |
C |
A |
14: 52,228,416 (GRCm39) |
C554* |
probably null |
Het |
| Atf6 |
T |
C |
1: 170,614,979 (GRCm39) |
Y538C |
probably damaging |
Het |
| Atp8b1 |
A |
C |
18: 64,671,749 (GRCm39) |
D1091E |
probably benign |
Het |
| BC034090 |
A |
G |
1: 155,102,010 (GRCm39) |
Y85H |
possibly damaging |
Het |
| Bcas2 |
A |
G |
3: 103,083,017 (GRCm39) |
|
probably benign |
Het |
| Bnc2 |
T |
C |
4: 84,211,056 (GRCm39) |
N463D |
probably damaging |
Het |
| Capn7 |
A |
T |
14: 31,081,216 (GRCm39) |
H411L |
possibly damaging |
Het |
| Cavin3 |
T |
C |
7: 105,130,320 (GRCm39) |
E164G |
probably damaging |
Het |
| Ccdc191 |
T |
C |
16: 43,759,536 (GRCm39) |
|
probably benign |
Het |
| Ccdc88b |
A |
G |
19: 6,830,368 (GRCm39) |
V858A |
probably benign |
Het |
| Clcn3 |
A |
G |
8: 61,383,685 (GRCm39) |
|
probably benign |
Het |
| Commd6 |
T |
C |
14: 101,877,720 (GRCm39) |
|
probably benign |
Het |
| Cspg4b |
C |
A |
13: 113,505,341 (GRCm39) |
L2157I |
probably damaging |
Het |
| Cspg4b |
T |
G |
13: 113,505,342 (GRCm39) |
L2157R |
probably damaging |
Het |
| Cul3 |
G |
A |
1: 80,249,391 (GRCm39) |
L561F |
probably damaging |
Het |
| Cyfip1 |
T |
A |
7: 55,524,761 (GRCm39) |
I131N |
probably damaging |
Het |
| Dlgap3 |
T |
A |
4: 127,127,554 (GRCm39) |
Y741N |
probably damaging |
Het |
| Dnaaf10 |
T |
C |
11: 17,179,794 (GRCm39) |
V265A |
probably benign |
Het |
| Dnah5 |
A |
T |
15: 28,295,406 (GRCm39) |
I1380F |
possibly damaging |
Het |
| Dync1h1 |
G |
T |
12: 110,628,975 (GRCm39) |
L4177F |
probably damaging |
Het |
| Ethe1 |
G |
A |
7: 24,307,319 (GRCm39) |
V178M |
probably damaging |
Het |
| Flnc |
A |
T |
6: 29,445,153 (GRCm39) |
|
probably null |
Het |
| Get3 |
C |
T |
8: 85,745,502 (GRCm39) |
A219T |
probably benign |
Het |
| Glt8d1 |
T |
C |
14: 30,728,649 (GRCm39) |
F26L |
probably benign |
Het |
| Gm5493 |
T |
A |
17: 22,967,054 (GRCm39) |
D63E |
probably benign |
Het |
| Gm9996 |
T |
A |
10: 29,019,834 (GRCm39) |
|
probably benign |
Het |
| Gnl2 |
T |
G |
4: 124,947,266 (GRCm39) |
S629R |
possibly damaging |
Het |
| Gpbp1l1 |
T |
C |
4: 116,447,462 (GRCm39) |
S381P |
probably damaging |
Het |
| Igsf10 |
A |
C |
3: 59,233,370 (GRCm39) |
F1788V |
probably benign |
Het |
| Inpp5d |
C |
A |
1: 87,642,864 (GRCm39) |
P935Q |
probably damaging |
Het |
| Itch |
A |
C |
2: 155,041,355 (GRCm39) |
I468L |
probably benign |
Het |
| Itga5 |
A |
T |
15: 103,265,637 (GRCm39) |
Y192N |
probably damaging |
Het |
| Itih3 |
T |
A |
14: 30,640,906 (GRCm39) |
Q302L |
probably null |
Het |
| Itih3 |
T |
A |
14: 30,643,643 (GRCm39) |
Q121L |
possibly damaging |
Het |
| Kctd17 |
T |
A |
15: 78,319,959 (GRCm39) |
|
probably benign |
Het |
| Lsm1 |
T |
C |
8: 26,283,717 (GRCm39) |
L43P |
probably damaging |
Het |
| Magi3 |
A |
T |
3: 103,923,141 (GRCm39) |
M1192K |
probably benign |
Het |
| Mecom |
A |
G |
3: 30,322,817 (GRCm39) |
|
probably benign |
Het |
| Minar1 |
A |
G |
9: 89,483,606 (GRCm39) |
V597A |
probably damaging |
Het |
| Mtmr3 |
A |
T |
11: 4,477,855 (GRCm39) |
F63Y |
probably benign |
Het |
| Naa16 |
A |
G |
14: 79,573,788 (GRCm39) |
|
probably benign |
Het |
| Neto1 |
A |
T |
18: 86,416,427 (GRCm39) |
T45S |
possibly damaging |
Het |
| Nlrp4a |
A |
T |
7: 26,149,654 (GRCm39) |
R420S |
probably damaging |
Het |
| Nr1h4 |
T |
C |
10: 89,309,736 (GRCm39) |
D317G |
probably damaging |
Het |
| Or8b53 |
A |
G |
9: 38,666,955 (GRCm39) |
|
probably benign |
Het |
| Or9i16 |
C |
T |
19: 13,864,765 (GRCm39) |
D270N |
probably damaging |
Het |
| Or9q2 |
T |
A |
19: 13,772,838 (GRCm39) |
I46F |
possibly damaging |
Het |
| Pde5a |
A |
T |
3: 122,541,542 (GRCm39) |
M11L |
possibly damaging |
Het |
| Polm |
A |
T |
11: 5,785,749 (GRCm39) |
Y141* |
probably null |
Het |
| Rxfp1 |
A |
G |
3: 79,612,975 (GRCm39) |
F32L |
probably damaging |
Het |
| Scrt1 |
T |
A |
15: 76,405,868 (GRCm39) |
D13V |
possibly damaging |
Het |
| Slc1a7 |
T |
A |
4: 107,834,871 (GRCm39) |
V79E |
possibly damaging |
Het |
| Snurf |
T |
C |
7: 59,645,270 (GRCm39) |
Q48R |
probably benign |
Het |
| Srek1 |
T |
C |
13: 103,894,695 (GRCm39) |
|
probably benign |
Het |
| Stxbp5l |
T |
C |
16: 37,076,246 (GRCm39) |
S267G |
probably damaging |
Het |
| Taf5 |
C |
T |
19: 47,063,409 (GRCm39) |
R320W |
probably damaging |
Het |
| Tars2 |
A |
T |
3: 95,660,403 (GRCm39) |
N106K |
probably damaging |
Het |
| Tatdn3 |
A |
T |
1: 190,781,531 (GRCm39) |
L207Q |
probably damaging |
Het |
| Tdrd6 |
T |
C |
17: 43,938,501 (GRCm39) |
E849G |
probably damaging |
Het |
| Tedc2 |
T |
C |
17: 24,438,985 (GRCm39) |
T111A |
probably benign |
Het |
| Tfg |
T |
A |
16: 56,514,854 (GRCm39) |
|
probably null |
Het |
| Tgds |
A |
T |
14: 118,353,643 (GRCm39) |
S225T |
probably benign |
Het |
| Tnks2 |
T |
A |
19: 36,852,671 (GRCm39) |
Y134* |
probably null |
Het |
| Trappc1 |
T |
A |
11: 69,216,356 (GRCm39) |
V134D |
probably damaging |
Het |
| Ttc3 |
C |
A |
16: 94,243,620 (GRCm39) |
P853Q |
probably damaging |
Het |
| Ttc7 |
C |
A |
17: 87,678,163 (GRCm39) |
|
probably benign |
Het |
| Ttf1 |
A |
G |
2: 28,964,606 (GRCm39) |
S643G |
probably damaging |
Het |
| Tubgcp3 |
A |
T |
8: 12,700,171 (GRCm39) |
S338T |
probably damaging |
Het |
| Ugt1a6a |
T |
C |
1: 88,067,007 (GRCm39) |
I271T |
possibly damaging |
Het |
| Vipas39 |
T |
A |
12: 87,288,075 (GRCm39) |
Y445F |
probably damaging |
Het |
| Vmn1r31 |
A |
C |
6: 58,448,998 (GRCm39) |
I289S |
probably damaging |
Het |
| Zfp112 |
A |
G |
7: 23,825,685 (GRCm39) |
E551G |
probably damaging |
Het |
| Zfp397 |
T |
A |
18: 24,093,854 (GRCm39) |
Y446* |
probably null |
Het |
| Zfp442 |
A |
T |
2: 150,251,526 (GRCm39) |
H124Q |
probably damaging |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1727:Plxnb1
|
UTSW |
9 |
108,930,125 (GRCm39) |
splice site |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2102:Plxnb1
|
UTSW |
9 |
108,944,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Plxnb1
|
UTSW |
9 |
108,939,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4796:Plxnb1
|
UTSW |
9 |
108,943,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Plxnb1
|
UTSW |
9 |
108,934,442 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5256:Plxnb1
|
UTSW |
9 |
108,943,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6193:Plxnb1
|
UTSW |
9 |
108,933,971 (GRCm39) |
missense |
probably benign |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- GATAGATGGCTTCAGGATTATCCC -3'
(R):5'- TCGCCATCGTACTGCACATG -3'
Sequencing Primer
(F):5'- ATCCCACTCATGTTTGGGGACATAG -3'
(R):5'- GCAGGTTGCCCATCTGTAC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation