Incidental Mutation 'R4676:Tdrd6'
| ID |
349619 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tdrd6
|
| Ensembl Gene |
ENSMUSG00000040140 |
| Gene Name |
tudor domain containing 6 |
| Synonyms |
|
| MMRRC Submission |
042013-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4676 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
43926226-43941190 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 43938501 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 849
(E849G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000035338
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045717]
[ENSMUST00000168073]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000045717
AA Change: E849G
PolyPhen 2
Score 0.958 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000035338
Gene: ENSMUSG00000040140
AA Change: E849G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
14 |
133 |
9.9e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2026 |
2083 |
9.45e-1 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000168073
AA Change: E849G
PolyPhen 2
Score 0.817 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000131277
Gene: ENSMUSG00000040140
AA Change: E849G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
12 |
133 |
7.2e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2027 |
2084 |
9.45e-1 |
SMART |
|
| Meta Mutation Damage Score |
0.1934 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.8%
|
| Validation Efficiency |
98% (93/95) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1). [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit male fertility associated with arrested spermatogenesis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3110009E18Rik |
T |
A |
1: 120,078,382 (GRCm39) |
I13N |
probably damaging |
Het |
| Abcd3 |
T |
A |
3: 121,567,815 (GRCm39) |
T409S |
possibly damaging |
Het |
| Acad12 |
C |
A |
5: 121,745,234 (GRCm39) |
W317L |
probably damaging |
Het |
| Acap1 |
T |
A |
11: 69,780,294 (GRCm39) |
M50L |
probably benign |
Het |
| Acvr1b |
T |
A |
15: 101,100,867 (GRCm39) |
V343E |
probably damaging |
Het |
| Adgb |
C |
A |
10: 10,302,454 (GRCm39) |
G371W |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,082,774 (GRCm39) |
K1966R |
probably damaging |
Het |
| Akap9 |
C |
T |
5: 4,114,515 (GRCm39) |
Q48* |
probably null |
Het |
| Ano10 |
T |
C |
9: 122,092,853 (GRCm39) |
R159G |
probably damaging |
Het |
| Anxa7 |
T |
C |
14: 20,517,983 (GRCm39) |
M128V |
probably benign |
Het |
| Arhgef40 |
C |
A |
14: 52,228,416 (GRCm39) |
C554* |
probably null |
Het |
| Atf6 |
T |
C |
1: 170,614,979 (GRCm39) |
Y538C |
probably damaging |
Het |
| Atp8b1 |
A |
C |
18: 64,671,749 (GRCm39) |
D1091E |
probably benign |
Het |
| BC034090 |
A |
G |
1: 155,102,010 (GRCm39) |
Y85H |
possibly damaging |
Het |
| Bcas2 |
A |
G |
3: 103,083,017 (GRCm39) |
|
probably benign |
Het |
| Bnc2 |
T |
C |
4: 84,211,056 (GRCm39) |
N463D |
probably damaging |
Het |
| Capn7 |
A |
T |
14: 31,081,216 (GRCm39) |
H411L |
possibly damaging |
Het |
| Cavin3 |
T |
C |
7: 105,130,320 (GRCm39) |
E164G |
probably damaging |
Het |
| Ccdc191 |
T |
C |
16: 43,759,536 (GRCm39) |
|
probably benign |
Het |
| Ccdc88b |
A |
G |
19: 6,830,368 (GRCm39) |
V858A |
probably benign |
Het |
| Clcn3 |
A |
G |
8: 61,383,685 (GRCm39) |
|
probably benign |
Het |
| Commd6 |
T |
C |
14: 101,877,720 (GRCm39) |
|
probably benign |
Het |
| Cspg4b |
C |
A |
13: 113,505,341 (GRCm39) |
L2157I |
probably damaging |
Het |
| Cspg4b |
T |
G |
13: 113,505,342 (GRCm39) |
L2157R |
probably damaging |
Het |
| Cul3 |
G |
A |
1: 80,249,391 (GRCm39) |
L561F |
probably damaging |
Het |
| Cyfip1 |
T |
A |
7: 55,524,761 (GRCm39) |
I131N |
probably damaging |
Het |
| Dlgap3 |
T |
A |
4: 127,127,554 (GRCm39) |
Y741N |
probably damaging |
Het |
| Dnaaf10 |
T |
C |
11: 17,179,794 (GRCm39) |
V265A |
probably benign |
Het |
| Dnah5 |
A |
T |
15: 28,295,406 (GRCm39) |
I1380F |
possibly damaging |
Het |
| Dync1h1 |
G |
T |
12: 110,628,975 (GRCm39) |
L4177F |
probably damaging |
Het |
| Ethe1 |
G |
A |
7: 24,307,319 (GRCm39) |
V178M |
probably damaging |
Het |
| Flnc |
A |
T |
6: 29,445,153 (GRCm39) |
|
probably null |
Het |
| Get3 |
C |
T |
8: 85,745,502 (GRCm39) |
A219T |
probably benign |
Het |
| Glt8d1 |
T |
C |
14: 30,728,649 (GRCm39) |
F26L |
probably benign |
Het |
| Gm5493 |
T |
A |
17: 22,967,054 (GRCm39) |
D63E |
probably benign |
Het |
| Gm9996 |
T |
A |
10: 29,019,834 (GRCm39) |
|
probably benign |
Het |
| Gnl2 |
T |
G |
4: 124,947,266 (GRCm39) |
S629R |
possibly damaging |
Het |
| Gpbp1l1 |
T |
C |
4: 116,447,462 (GRCm39) |
S381P |
probably damaging |
Het |
| Igsf10 |
A |
C |
3: 59,233,370 (GRCm39) |
F1788V |
probably benign |
Het |
| Inpp5d |
C |
A |
1: 87,642,864 (GRCm39) |
P935Q |
probably damaging |
Het |
| Itch |
A |
C |
2: 155,041,355 (GRCm39) |
I468L |
probably benign |
Het |
| Itga5 |
A |
T |
15: 103,265,637 (GRCm39) |
Y192N |
probably damaging |
Het |
| Itih3 |
T |
A |
14: 30,640,906 (GRCm39) |
Q302L |
probably null |
Het |
| Itih3 |
T |
A |
14: 30,643,643 (GRCm39) |
Q121L |
possibly damaging |
Het |
| Kctd17 |
T |
A |
15: 78,319,959 (GRCm39) |
|
probably benign |
Het |
| Lsm1 |
T |
C |
8: 26,283,717 (GRCm39) |
L43P |
probably damaging |
Het |
| Magi3 |
A |
T |
3: 103,923,141 (GRCm39) |
M1192K |
probably benign |
Het |
| Mecom |
A |
G |
3: 30,322,817 (GRCm39) |
|
probably benign |
Het |
| Minar1 |
A |
G |
9: 89,483,606 (GRCm39) |
V597A |
probably damaging |
Het |
| Mtmr3 |
A |
T |
11: 4,477,855 (GRCm39) |
F63Y |
probably benign |
Het |
| Naa16 |
A |
G |
14: 79,573,788 (GRCm39) |
|
probably benign |
Het |
| Neto1 |
A |
T |
18: 86,416,427 (GRCm39) |
T45S |
possibly damaging |
Het |
| Nlrp4a |
A |
T |
7: 26,149,654 (GRCm39) |
R420S |
probably damaging |
Het |
| Nr1h4 |
T |
C |
10: 89,309,736 (GRCm39) |
D317G |
probably damaging |
Het |
| Or8b53 |
A |
G |
9: 38,666,955 (GRCm39) |
|
probably benign |
Het |
| Or9i16 |
C |
T |
19: 13,864,765 (GRCm39) |
D270N |
probably damaging |
Het |
| Or9q2 |
T |
A |
19: 13,772,838 (GRCm39) |
I46F |
possibly damaging |
Het |
| Pde5a |
A |
T |
3: 122,541,542 (GRCm39) |
M11L |
possibly damaging |
Het |
| Plxnb1 |
G |
A |
9: 108,939,503 (GRCm39) |
R1416Q |
possibly damaging |
Het |
| Polm |
A |
T |
11: 5,785,749 (GRCm39) |
Y141* |
probably null |
Het |
| Rxfp1 |
A |
G |
3: 79,612,975 (GRCm39) |
F32L |
probably damaging |
Het |
| Scrt1 |
T |
A |
15: 76,405,868 (GRCm39) |
D13V |
possibly damaging |
Het |
| Slc1a7 |
T |
A |
4: 107,834,871 (GRCm39) |
V79E |
possibly damaging |
Het |
| Snurf |
T |
C |
7: 59,645,270 (GRCm39) |
Q48R |
probably benign |
Het |
| Srek1 |
T |
C |
13: 103,894,695 (GRCm39) |
|
probably benign |
Het |
| Stxbp5l |
T |
C |
16: 37,076,246 (GRCm39) |
S267G |
probably damaging |
Het |
| Taf5 |
C |
T |
19: 47,063,409 (GRCm39) |
R320W |
probably damaging |
Het |
| Tars2 |
A |
T |
3: 95,660,403 (GRCm39) |
N106K |
probably damaging |
Het |
| Tatdn3 |
A |
T |
1: 190,781,531 (GRCm39) |
L207Q |
probably damaging |
Het |
| Tedc2 |
T |
C |
17: 24,438,985 (GRCm39) |
T111A |
probably benign |
Het |
| Tfg |
T |
A |
16: 56,514,854 (GRCm39) |
|
probably null |
Het |
| Tgds |
A |
T |
14: 118,353,643 (GRCm39) |
S225T |
probably benign |
Het |
| Tnks2 |
T |
A |
19: 36,852,671 (GRCm39) |
Y134* |
probably null |
Het |
| Trappc1 |
T |
A |
11: 69,216,356 (GRCm39) |
V134D |
probably damaging |
Het |
| Ttc3 |
C |
A |
16: 94,243,620 (GRCm39) |
P853Q |
probably damaging |
Het |
| Ttc7 |
C |
A |
17: 87,678,163 (GRCm39) |
|
probably benign |
Het |
| Ttf1 |
A |
G |
2: 28,964,606 (GRCm39) |
S643G |
probably damaging |
Het |
| Tubgcp3 |
A |
T |
8: 12,700,171 (GRCm39) |
S338T |
probably damaging |
Het |
| Ugt1a6a |
T |
C |
1: 88,067,007 (GRCm39) |
I271T |
possibly damaging |
Het |
| Vipas39 |
T |
A |
12: 87,288,075 (GRCm39) |
Y445F |
probably damaging |
Het |
| Vmn1r31 |
A |
C |
6: 58,448,998 (GRCm39) |
I289S |
probably damaging |
Het |
| Zfp112 |
A |
G |
7: 23,825,685 (GRCm39) |
E551G |
probably damaging |
Het |
| Zfp397 |
T |
A |
18: 24,093,854 (GRCm39) |
Y446* |
probably null |
Het |
| Zfp442 |
A |
T |
2: 150,251,526 (GRCm39) |
H124Q |
probably damaging |
Het |
|
| Other mutations in Tdrd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00571:Tdrd6
|
APN |
17 |
43,939,051 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00844:Tdrd6
|
APN |
17 |
43,928,087 (GRCm39) |
missense |
probably benign |
|
|
IGL00845:Tdrd6
|
APN |
17 |
43,937,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,936,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,935,657 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01575:Tdrd6
|
APN |
17 |
43,938,871 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01812:Tdrd6
|
APN |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02013:Tdrd6
|
APN |
17 |
43,936,837 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02067:Tdrd6
|
APN |
17 |
43,939,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02112:Tdrd6
|
APN |
17 |
43,940,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02159:Tdrd6
|
APN |
17 |
43,939,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02226:Tdrd6
|
APN |
17 |
43,938,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02416:Tdrd6
|
APN |
17 |
43,935,629 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02577:Tdrd6
|
APN |
17 |
43,937,728 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02631:Tdrd6
|
APN |
17 |
43,937,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02738:Tdrd6
|
APN |
17 |
43,931,337 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02792:Tdrd6
|
APN |
17 |
43,935,918 (GRCm39) |
missense |
probably benign |
|
|
IGL02929:Tdrd6
|
APN |
17 |
43,940,604 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02934:Tdrd6
|
APN |
17 |
43,938,778 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02954:Tdrd6
|
APN |
17 |
43,938,153 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02969:Tdrd6
|
APN |
17 |
43,938,440 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03006:Tdrd6
|
APN |
17 |
43,936,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03155:Tdrd6
|
APN |
17 |
43,936,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03219:Tdrd6
|
APN |
17 |
43,938,855 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03372:Tdrd6
|
APN |
17 |
43,936,459 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Edward
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
eliza
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
Elizabeth
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
henry
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
BB001:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
BB011:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
G1citation:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0030:Tdrd6
|
UTSW |
17 |
43,937,482 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0057:Tdrd6
|
UTSW |
17 |
43,928,052 (GRCm39) |
splice site |
probably benign |
|
|
R0090:Tdrd6
|
UTSW |
17 |
43,939,132 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Tdrd6
|
UTSW |
17 |
43,935,199 (GRCm39) |
missense |
probably benign |
|
|
R0463:Tdrd6
|
UTSW |
17 |
43,936,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Tdrd6
|
UTSW |
17 |
43,940,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0650:Tdrd6
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1226:Tdrd6
|
UTSW |
17 |
43,937,523 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1309:Tdrd6
|
UTSW |
17 |
43,937,512 (GRCm39) |
missense |
probably benign |
|
|
R1483:Tdrd6
|
UTSW |
17 |
43,938,498 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1561:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1574:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1647:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1648:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1723:Tdrd6
|
UTSW |
17 |
43,939,218 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1786:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1819:Tdrd6
|
UTSW |
17 |
43,937,442 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1836:Tdrd6
|
UTSW |
17 |
43,936,480 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1892:Tdrd6
|
UTSW |
17 |
43,935,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1911:Tdrd6
|
UTSW |
17 |
43,937,979 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1936:Tdrd6
|
UTSW |
17 |
43,937,358 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2005:Tdrd6
|
UTSW |
17 |
43,939,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2006:Tdrd6
|
UTSW |
17 |
43,939,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2133:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3010:Tdrd6
|
UTSW |
17 |
43,938,933 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4225:Tdrd6
|
UTSW |
17 |
43,936,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4449:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4531:Tdrd6
|
UTSW |
17 |
43,939,645 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4624:Tdrd6
|
UTSW |
17 |
43,936,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4665:Tdrd6
|
UTSW |
17 |
43,935,007 (GRCm39) |
missense |
probably benign |
|
|
R4785:Tdrd6
|
UTSW |
17 |
43,936,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4912:Tdrd6
|
UTSW |
17 |
43,935,218 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5134:Tdrd6
|
UTSW |
17 |
43,937,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5145:Tdrd6
|
UTSW |
17 |
43,936,966 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5623:Tdrd6
|
UTSW |
17 |
43,940,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5712:Tdrd6
|
UTSW |
17 |
43,937,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Tdrd6
|
UTSW |
17 |
43,935,768 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5913:Tdrd6
|
UTSW |
17 |
43,939,302 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6142:Tdrd6
|
UTSW |
17 |
43,940,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6181:Tdrd6
|
UTSW |
17 |
43,939,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6195:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6289:Tdrd6
|
UTSW |
17 |
43,935,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6315:Tdrd6
|
UTSW |
17 |
43,937,229 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6578:Tdrd6
|
UTSW |
17 |
43,939,852 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6645:Tdrd6
|
UTSW |
17 |
43,935,423 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6822:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7000:Tdrd6
|
UTSW |
17 |
43,938,599 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7075:Tdrd6
|
UTSW |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7107:Tdrd6
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7381:Tdrd6
|
UTSW |
17 |
43,936,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7458:Tdrd6
|
UTSW |
17 |
43,935,937 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7461:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7505:Tdrd6
|
UTSW |
17 |
43,938,570 (GRCm39) |
missense |
not run |
|
|
R7583:Tdrd6
|
UTSW |
17 |
43,935,129 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7613:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7723:Tdrd6
|
UTSW |
17 |
43,936,851 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7759:Tdrd6
|
UTSW |
17 |
43,935,730 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7924:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8002:Tdrd6
|
UTSW |
17 |
43,940,710 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8134:Tdrd6
|
UTSW |
17 |
43,937,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8231:Tdrd6
|
UTSW |
17 |
43,933,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8242:Tdrd6
|
UTSW |
17 |
43,939,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8542:Tdrd6
|
UTSW |
17 |
43,935,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8713:Tdrd6
|
UTSW |
17 |
43,935,910 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9100:Tdrd6
|
UTSW |
17 |
43,936,305 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9201:Tdrd6
|
UTSW |
17 |
43,936,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9222:Tdrd6
|
UTSW |
17 |
43,939,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9369:Tdrd6
|
UTSW |
17 |
43,936,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9373:Tdrd6
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9384:Tdrd6
|
UTSW |
17 |
43,937,783 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9448:Tdrd6
|
UTSW |
17 |
43,936,567 (GRCm39) |
missense |
probably benign |
|
|
R9534:Tdrd6
|
UTSW |
17 |
43,936,510 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9613:Tdrd6
|
UTSW |
17 |
43,939,518 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,884 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,044 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1088:Tdrd6
|
UTSW |
17 |
43,937,409 (GRCm39) |
missense |
probably benign |
0.23 |
|
Z1177:Tdrd6
|
UTSW |
17 |
43,938,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGATGAACCCGCTGAAAGC -3'
(R):5'- TCTCACATCGAAAACCCTGG -3'
Sequencing Primer
(F):5'- ACCCGCTGAAAGCCTGTACTG -3'
(R):5'- GAAAACCCTGGCTCCTTCTGG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation