Incidental Mutation 'R4669:Ltn1'
| ID |
352308 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ltn1
|
| Ensembl Gene |
ENSMUSG00000052299 |
| Gene Name |
listerin E3 ubiquitin protein ligase 1 |
| Synonyms |
Listerin, Zfp294, Rnf160, 4930528H02Rik |
| MMRRC Submission |
041925-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4669 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
87173539-87229500 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 87215375 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 420
(M420K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156299
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039449]
[ENSMUST00000232095]
|
| AlphaFold |
Q6A009 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000039449
AA Change: M420K
PolyPhen 2
Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000038775
Gene: ENSMUSG00000052299
AA Change: M420K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
176 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
410 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
522 |
N/A |
INTRINSIC |
|
low complexity region
|
553 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
832 |
N/A |
INTRINSIC |
|
low complexity region
|
1380 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1451 |
N/A |
INTRINSIC |
|
RING
|
1716 |
1762 |
1.05e-1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000083713
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000232095
AA Change: M420K
PolyPhen 2
Score 0.904 (Sensitivity: 0.82; Specificity: 0.94)
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM, Nov 2010]
PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Mice homozygous for a point mutation display progressive neuron degeneration and age dependent motor deficits. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad8 |
A |
G |
9: 26,901,923 (GRCm39) |
L147P |
probably damaging |
Het |
| Acan |
A |
G |
7: 78,750,890 (GRCm39) |
E464G |
probably benign |
Het |
| Agap1 |
A |
G |
1: 89,765,528 (GRCm39) |
|
probably null |
Het |
| Akap13 |
A |
G |
7: 75,378,842 (GRCm39) |
T2128A |
probably damaging |
Het |
| Ap2a1 |
A |
T |
7: 44,552,343 (GRCm39) |
|
probably benign |
Het |
| Arap3 |
T |
C |
18: 38,129,307 (GRCm39) |
D217G |
probably benign |
Het |
| Arl2 |
C |
A |
19: 6,184,716 (GRCm39) |
R179L |
probably damaging |
Het |
| Atg2a |
T |
A |
19: 6,309,017 (GRCm39) |
|
probably null |
Het |
| B3gat1 |
T |
A |
9: 26,663,052 (GRCm39) |
L6Q |
probably benign |
Het |
| Bcl10 |
A |
G |
3: 145,636,327 (GRCm39) |
N75S |
probably damaging |
Het |
| Bmpr2 |
T |
C |
1: 59,906,875 (GRCm39) |
L656S |
probably damaging |
Het |
| Brms1l |
A |
G |
12: 55,888,356 (GRCm39) |
E48G |
possibly damaging |
Het |
| C2cd2l |
A |
T |
9: 44,226,322 (GRCm39) |
N414K |
possibly damaging |
Het |
| Capn2 |
C |
T |
1: 182,298,345 (GRCm39) |
C640Y |
probably benign |
Het |
| Ccdc153 |
G |
T |
9: 44,157,021 (GRCm39) |
R99M |
probably damaging |
Het |
| Ccdc51 |
A |
G |
9: 108,920,030 (GRCm39) |
N142S |
probably benign |
Het |
| Cdipt |
A |
G |
7: 126,577,578 (GRCm39) |
H108R |
possibly damaging |
Het |
| Ceacam20 |
T |
C |
7: 19,719,952 (GRCm39) |
Y495H |
probably damaging |
Het |
| Celf2 |
T |
C |
2: 6,726,339 (GRCm39) |
I47V |
probably benign |
Het |
| Cts3 |
C |
T |
13: 61,714,637 (GRCm39) |
E223K |
probably benign |
Het |
| Cyp2a22 |
T |
C |
7: 26,637,280 (GRCm39) |
D168G |
possibly damaging |
Het |
| Cyp2c67 |
T |
A |
19: 39,632,098 (GRCm39) |
H90L |
probably benign |
Het |
| Ddx4 |
T |
C |
13: 112,758,778 (GRCm39) |
Y261C |
probably damaging |
Het |
| Dnah17 |
T |
C |
11: 117,965,119 (GRCm39) |
T2308A |
probably benign |
Het |
| Dnah6 |
T |
C |
6: 73,014,671 (GRCm39) |
T3587A |
probably damaging |
Het |
| Dpy19l1 |
C |
T |
9: 24,343,664 (GRCm39) |
V494I |
possibly damaging |
Het |
| Dse |
T |
G |
10: 34,029,008 (GRCm39) |
Y694S |
probably damaging |
Het |
| Emilin3 |
T |
C |
2: 160,752,717 (GRCm39) |
I78V |
probably benign |
Het |
| Esam |
T |
A |
9: 37,447,952 (GRCm39) |
Y195* |
probably null |
Het |
| Extl3 |
T |
A |
14: 65,313,745 (GRCm39) |
N479I |
possibly damaging |
Het |
| Fat2 |
A |
G |
11: 55,202,441 (GRCm39) |
V211A |
probably benign |
Het |
| Ganc |
G |
T |
2: 120,261,548 (GRCm39) |
V343F |
probably benign |
Het |
| Ggt5 |
T |
C |
10: 75,438,865 (GRCm39) |
L121P |
probably damaging |
Het |
| Gnmt |
A |
T |
17: 47,037,225 (GRCm39) |
C186* |
probably null |
Het |
| Gpr75 |
A |
T |
11: 30,842,072 (GRCm39) |
I326F |
probably damaging |
Het |
| Gsdme |
C |
T |
6: 50,185,102 (GRCm39) |
V451M |
probably damaging |
Het |
| H2-T23 |
G |
T |
17: 36,342,690 (GRCm39) |
D149E |
probably damaging |
Het |
| Hmcn2 |
G |
T |
2: 31,325,804 (GRCm39) |
R4277L |
probably benign |
Het |
| Irf9 |
C |
A |
14: 55,843,223 (GRCm39) |
H94N |
probably benign |
Het |
| Jhy |
T |
C |
9: 40,872,449 (GRCm39) |
N20S |
probably benign |
Het |
| Klf17 |
C |
A |
4: 117,617,568 (GRCm39) |
C263F |
probably damaging |
Het |
| Lama5 |
T |
C |
2: 179,822,430 (GRCm39) |
Y2881C |
probably damaging |
Het |
| Lig1 |
T |
G |
7: 13,044,953 (GRCm39) |
I882S |
probably damaging |
Het |
| Mael |
T |
C |
1: 166,063,077 (GRCm39) |
E125G |
probably damaging |
Het |
| Mib2 |
C |
T |
4: 155,741,872 (GRCm39) |
D275N |
possibly damaging |
Het |
| Mical3 |
C |
T |
6: 120,934,664 (GRCm39) |
R1805Q |
probably damaging |
Het |
| Mix23 |
A |
G |
16: 35,903,089 (GRCm39) |
D27G |
probably damaging |
Het |
| Mllt10 |
A |
G |
2: 18,208,444 (GRCm39) |
D158G |
probably damaging |
Het |
| Mocs1 |
A |
G |
17: 49,761,613 (GRCm39) |
D569G |
possibly damaging |
Het |
| Msh6 |
T |
C |
17: 88,292,234 (GRCm39) |
S330P |
possibly damaging |
Het |
| Mtmr2 |
T |
C |
9: 13,707,260 (GRCm39) |
S199P |
probably damaging |
Het |
| Ndufaf5 |
T |
C |
2: 140,029,675 (GRCm39) |
V164A |
probably benign |
Het |
| Nek9 |
T |
C |
12: 85,360,978 (GRCm39) |
E518G |
probably benign |
Het |
| Nfatc2 |
T |
C |
2: 168,413,410 (GRCm39) |
I72V |
probably benign |
Het |
| Nlrp9c |
C |
T |
7: 26,074,793 (GRCm39) |
A746T |
possibly damaging |
Het |
| Nup42 |
A |
G |
5: 24,387,415 (GRCm39) |
R402G |
probably benign |
Het |
| Ogdh |
G |
T |
11: 6,290,600 (GRCm39) |
C406F |
probably benign |
Het |
| Or3a1d |
A |
G |
11: 74,237,789 (GRCm39) |
V207A |
probably benign |
Het |
| Or4c120 |
G |
A |
2: 89,001,245 (GRCm39) |
H104Y |
probably damaging |
Het |
| Or8b35 |
A |
T |
9: 37,904,381 (GRCm39) |
I198F |
possibly damaging |
Het |
| Or8g17 |
T |
A |
9: 38,930,675 (GRCm39) |
Y54F |
probably benign |
Het |
| Or8j3 |
A |
T |
2: 86,028,277 (GRCm39) |
M273K |
possibly damaging |
Het |
| Otof |
A |
G |
5: 30,578,318 (GRCm39) |
|
probably null |
Het |
| Pcdhb17 |
T |
C |
18: 37,619,259 (GRCm39) |
S350P |
probably damaging |
Het |
| Phf3 |
T |
C |
1: 30,869,027 (GRCm39) |
T674A |
probably damaging |
Het |
| Pikfyve |
T |
A |
1: 65,289,432 (GRCm39) |
C1235S |
probably damaging |
Het |
| Ppfia3 |
T |
C |
7: 45,001,517 (GRCm39) |
E465G |
probably damaging |
Het |
| Prkg1 |
T |
A |
19: 31,641,639 (GRCm39) |
I15F |
probably damaging |
Het |
| Rab5c |
A |
G |
11: 100,610,843 (GRCm39) |
F22L |
probably damaging |
Het |
| Raf1 |
A |
G |
6: 115,609,880 (GRCm39) |
S220P |
probably damaging |
Het |
| Rgl1 |
T |
G |
1: 152,397,122 (GRCm39) |
R716S |
probably damaging |
Het |
| Rhbg |
C |
A |
3: 88,153,273 (GRCm39) |
W205L |
probably damaging |
Het |
| Rimbp3 |
A |
G |
16: 17,027,053 (GRCm39) |
E159G |
possibly damaging |
Het |
| Ryr1 |
T |
C |
7: 28,759,256 (GRCm39) |
D3338G |
probably null |
Het |
| Sash1 |
T |
C |
10: 8,606,149 (GRCm39) |
N747S |
probably benign |
Het |
| Serpina3g |
A |
T |
12: 104,205,479 (GRCm39) |
I73F |
probably damaging |
Het |
| Sfxn2 |
C |
A |
19: 46,574,213 (GRCm39) |
N134K |
probably damaging |
Het |
| Slc12a6 |
A |
G |
2: 112,184,640 (GRCm39) |
H853R |
probably damaging |
Het |
| Slc16a12 |
C |
T |
19: 34,649,965 (GRCm39) |
D357N |
probably damaging |
Het |
| Slc39a8 |
T |
C |
3: 135,561,772 (GRCm39) |
Y164H |
probably benign |
Het |
| Snx9 |
A |
G |
17: 5,977,499 (GRCm39) |
K518E |
probably damaging |
Het |
| Spdye4c |
G |
A |
2: 128,434,273 (GRCm39) |
V5I |
possibly damaging |
Het |
| Spef2 |
A |
G |
15: 9,676,459 (GRCm39) |
V704A |
probably benign |
Het |
| Stard3nl |
T |
A |
13: 19,560,689 (GRCm39) |
N29Y |
probably damaging |
Het |
| Strap |
C |
A |
6: 137,712,384 (GRCm39) |
S11* |
probably null |
Het |
| Synpo2 |
A |
G |
3: 122,906,712 (GRCm39) |
L868P |
probably damaging |
Het |
| Tenm2 |
A |
G |
11: 35,901,314 (GRCm39) |
V2474A |
probably damaging |
Het |
| Tm9sf4 |
T |
A |
2: 153,029,228 (GRCm39) |
V92D |
probably damaging |
Het |
| Tmf1 |
A |
T |
6: 97,147,388 (GRCm39) |
M526K |
probably benign |
Het |
| Top2b |
T |
G |
14: 16,409,189 (GRCm38) |
I777M |
probably damaging |
Het |
| Ttc39d |
A |
G |
17: 80,525,068 (GRCm39) |
I576V |
probably benign |
Het |
| Upk1a |
T |
G |
7: 30,304,554 (GRCm39) |
T193P |
probably benign |
Het |
| Vmn2r67 |
A |
T |
7: 84,799,732 (GRCm39) |
V502E |
probably benign |
Het |
| Wdr17 |
A |
G |
8: 55,143,083 (GRCm39) |
V189A |
possibly damaging |
Het |
| Wrap73 |
A |
T |
4: 154,236,153 (GRCm39) |
S161C |
probably benign |
Het |
| Zfp568 |
A |
G |
7: 29,722,702 (GRCm39) |
H549R |
probably damaging |
Het |
| Zfp605 |
T |
A |
5: 110,275,227 (GRCm39) |
M115K |
possibly damaging |
Het |
| Zp1 |
T |
A |
19: 10,896,269 (GRCm39) |
H152L |
probably benign |
Het |
|
| Other mutations in Ltn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00328:Ltn1
|
APN |
16 |
87,215,378 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01139:Ltn1
|
APN |
16 |
87,212,897 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01359:Ltn1
|
APN |
16 |
87,202,581 (GRCm39) |
splice site |
probably benign |
|
|
IGL01503:Ltn1
|
APN |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably benign |
|
|
IGL01529:Ltn1
|
APN |
16 |
87,178,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02437:Ltn1
|
APN |
16 |
87,194,889 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02658:Ltn1
|
APN |
16 |
87,212,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02890:Ltn1
|
APN |
16 |
87,206,185 (GRCm39) |
splice site |
probably null |
|
|
IGL02899:Ltn1
|
APN |
16 |
87,179,547 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02902:Ltn1
|
APN |
16 |
87,176,693 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL03128:Ltn1
|
APN |
16 |
87,212,832 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03392:Ltn1
|
APN |
16 |
87,222,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03046:Ltn1
|
UTSW |
16 |
87,202,509 (GRCm39) |
missense |
probably benign |
0.10 |
|
PIT4305001:Ltn1
|
UTSW |
16 |
87,217,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4366001:Ltn1
|
UTSW |
16 |
87,177,728 (GRCm39) |
nonsense |
probably null |
|
|
R0126:Ltn1
|
UTSW |
16 |
87,222,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0164:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0165:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0280:Ltn1
|
UTSW |
16 |
87,194,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0565:Ltn1
|
UTSW |
16 |
87,212,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0733:Ltn1
|
UTSW |
16 |
87,209,395 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1034:Ltn1
|
UTSW |
16 |
87,194,025 (GRCm39) |
splice site |
probably null |
|
|
R1252:Ltn1
|
UTSW |
16 |
87,212,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1524:Ltn1
|
UTSW |
16 |
87,178,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1746:Ltn1
|
UTSW |
16 |
87,208,669 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1826:Ltn1
|
UTSW |
16 |
87,212,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Ltn1
|
UTSW |
16 |
87,197,034 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1839:Ltn1
|
UTSW |
16 |
87,213,152 (GRCm39) |
nonsense |
probably null |
|
|
R1860:Ltn1
|
UTSW |
16 |
87,213,231 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1997:Ltn1
|
UTSW |
16 |
87,178,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Ltn1
|
UTSW |
16 |
87,212,530 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2134:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2135:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Ltn1
|
UTSW |
16 |
87,224,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2307:Ltn1
|
UTSW |
16 |
87,229,312 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2376:Ltn1
|
UTSW |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3054:Ltn1
|
UTSW |
16 |
87,200,961 (GRCm39) |
missense |
probably benign |
0.32 |
|
R3404:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3405:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3618:Ltn1
|
UTSW |
16 |
87,217,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4065:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4066:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4067:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4288:Ltn1
|
UTSW |
16 |
87,194,876 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4436:Ltn1
|
UTSW |
16 |
87,202,502 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4535:Ltn1
|
UTSW |
16 |
87,223,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Ltn1
|
UTSW |
16 |
87,198,912 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4715:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4830:Ltn1
|
UTSW |
16 |
87,176,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Ltn1
|
UTSW |
16 |
87,195,697 (GRCm39) |
nonsense |
probably null |
|
|
R4961:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R4992:Ltn1
|
UTSW |
16 |
87,202,475 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5073:Ltn1
|
UTSW |
16 |
87,224,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5288:Ltn1
|
UTSW |
16 |
87,212,899 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5802:Ltn1
|
UTSW |
16 |
87,212,569 (GRCm39) |
missense |
probably benign |
0.17 |
|
R5907:Ltn1
|
UTSW |
16 |
87,178,391 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6180:Ltn1
|
UTSW |
16 |
87,224,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6194:Ltn1
|
UTSW |
16 |
87,212,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6257:Ltn1
|
UTSW |
16 |
87,208,662 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6301:Ltn1
|
UTSW |
16 |
87,217,194 (GRCm39) |
missense |
probably benign |
|
|
R6481:Ltn1
|
UTSW |
16 |
87,175,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6525:Ltn1
|
UTSW |
16 |
87,217,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R6969:Ltn1
|
UTSW |
16 |
87,212,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Ltn1
|
UTSW |
16 |
87,220,361 (GRCm39) |
missense |
probably benign |
|
|
R7038:Ltn1
|
UTSW |
16 |
87,221,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7062:Ltn1
|
UTSW |
16 |
87,224,491 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7152:Ltn1
|
UTSW |
16 |
87,224,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7247:Ltn1
|
UTSW |
16 |
87,206,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7454:Ltn1
|
UTSW |
16 |
87,194,700 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7471:Ltn1
|
UTSW |
16 |
87,194,787 (GRCm39) |
missense |
probably benign |
|
|
R7511:Ltn1
|
UTSW |
16 |
87,205,716 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7691:Ltn1
|
UTSW |
16 |
87,195,574 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7702:Ltn1
|
UTSW |
16 |
87,223,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7761:Ltn1
|
UTSW |
16 |
87,208,681 (GRCm39) |
missense |
probably benign |
|
|
R8002:Ltn1
|
UTSW |
16 |
87,212,835 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8101:Ltn1
|
UTSW |
16 |
87,215,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8142:Ltn1
|
UTSW |
16 |
87,178,529 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8214:Ltn1
|
UTSW |
16 |
87,177,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8674:Ltn1
|
UTSW |
16 |
87,195,673 (GRCm39) |
missense |
probably benign |
|
|
R8783:Ltn1
|
UTSW |
16 |
87,207,247 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8839:Ltn1
|
UTSW |
16 |
87,215,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8885:Ltn1
|
UTSW |
16 |
87,178,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8889:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8892:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8919:Ltn1
|
UTSW |
16 |
87,178,381 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8970:Ltn1
|
UTSW |
16 |
87,212,926 (GRCm39) |
missense |
probably benign |
|
|
R9113:Ltn1
|
UTSW |
16 |
87,224,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9208:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9234:Ltn1
|
UTSW |
16 |
87,194,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9421:Ltn1
|
UTSW |
16 |
87,215,375 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9558:Ltn1
|
UTSW |
16 |
87,220,295 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9654:Ltn1
|
UTSW |
16 |
87,207,227 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9738:Ltn1
|
UTSW |
16 |
87,222,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0028:Ltn1
|
UTSW |
16 |
87,199,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Ltn1
|
UTSW |
16 |
87,198,925 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GAAATCATTTGGAAGGCTAACTGC -3'
(R):5'- GTTTTCATTCAGCGGGATTCC -3'
Sequencing Primer
(F):5'- ACACAGTGAGCTTGAGTCTTTC -3'
(R):5'- CATTCAGCGGGATTCCTTTTTAG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation