Incidental Mutation 'R4660:Iqgap3'
| ID |
352737 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
041920-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.314)
|
| Stock # |
R4660 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 88027483 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Arginine
at position 702
(L702R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142035
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071812
AA Change: L1600R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: L1600R
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000194440
AA Change: L702R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
AA Change: L702R
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.6043 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
96% (102/106) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adra1d |
T |
C |
2: 131,403,062 (GRCm39) |
T343A |
probably damaging |
Het |
| Angptl4 |
A |
T |
17: 33,996,249 (GRCm39) |
|
probably benign |
Het |
| Antxr2 |
A |
T |
5: 98,151,913 (GRCm39) |
|
probably null |
Het |
| Ap1b1 |
T |
A |
11: 4,966,760 (GRCm39) |
V145E |
probably damaging |
Het |
| Asns |
G |
T |
6: 7,678,012 (GRCm39) |
N355K |
probably benign |
Het |
| Asxl3 |
A |
G |
18: 22,649,534 (GRCm39) |
T508A |
probably benign |
Het |
| B4galt7 |
T |
A |
13: 55,752,111 (GRCm39) |
V54D |
possibly damaging |
Het |
| Bach2 |
C |
T |
4: 32,562,777 (GRCm39) |
P415S |
probably benign |
Het |
| Bbs9 |
G |
A |
9: 22,490,063 (GRCm39) |
R278Q |
probably benign |
Het |
| Blzf1 |
C |
T |
1: 164,134,062 (GRCm39) |
|
probably benign |
Het |
| Btd |
A |
T |
14: 31,389,760 (GRCm39) |
T494S |
probably benign |
Het |
| Casp9 |
C |
T |
4: 141,540,934 (GRCm39) |
T434I |
probably benign |
Het |
| Cavin2 |
T |
C |
1: 51,340,510 (GRCm39) |
S396P |
probably benign |
Het |
| Ccnk |
C |
T |
12: 108,168,575 (GRCm39) |
|
probably benign |
Het |
| Cldn8 |
G |
A |
16: 88,359,296 (GRCm39) |
H210Y |
probably benign |
Het |
| Clip1 |
G |
A |
5: 123,717,437 (GRCm39) |
T1284I |
probably damaging |
Het |
| Coch |
T |
C |
12: 51,642,268 (GRCm39) |
V80A |
probably benign |
Het |
| Cttnbp2 |
A |
G |
6: 18,406,536 (GRCm39) |
S1052P |
probably benign |
Het |
| Cyp2j7 |
C |
T |
4: 96,083,579 (GRCm39) |
R457K |
probably benign |
Het |
| Dalrd3 |
T |
C |
9: 108,447,568 (GRCm39) |
S129P |
probably benign |
Het |
| Ddx10 |
A |
G |
9: 53,147,698 (GRCm39) |
|
probably null |
Het |
| Dnah7b |
A |
T |
1: 46,328,696 (GRCm39) |
T3143S |
probably damaging |
Het |
| Dynlt1b |
A |
G |
17: 6,699,279 (GRCm39) |
T10A |
probably benign |
Het |
| Eif2s2 |
G |
A |
2: 154,730,189 (GRCm39) |
T36I |
probably benign |
Het |
| Fam118b |
A |
T |
9: 35,146,551 (GRCm39) |
H105Q |
possibly damaging |
Het |
| Galntl5 |
T |
A |
5: 25,408,377 (GRCm39) |
I250N |
probably damaging |
Het |
| Gm11544 |
C |
T |
11: 94,736,306 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5709 |
C |
T |
3: 59,526,124 (GRCm39) |
|
noncoding transcript |
Het |
| Golgb1 |
T |
A |
16: 36,707,980 (GRCm39) |
I107N |
probably damaging |
Het |
| Gpld1 |
T |
C |
13: 25,166,586 (GRCm39) |
|
probably null |
Het |
| Grik1 |
T |
A |
16: 87,720,019 (GRCm39) |
T768S |
probably damaging |
Het |
| H2-T23 |
T |
G |
17: 36,341,108 (GRCm39) |
Q349P |
probably damaging |
Het |
| Ing3 |
A |
T |
6: 21,973,710 (GRCm39) |
|
probably benign |
Het |
| Itga8 |
A |
G |
2: 12,270,069 (GRCm39) |
V139A |
probably damaging |
Het |
| Jam2 |
G |
A |
16: 84,609,840 (GRCm39) |
V151M |
probably damaging |
Het |
| Kbtbd12 |
T |
C |
6: 88,594,772 (GRCm39) |
I353V |
probably benign |
Het |
| Kif27 |
T |
C |
13: 58,471,730 (GRCm39) |
E786G |
probably damaging |
Het |
| Lingo4 |
T |
A |
3: 94,310,672 (GRCm39) |
S537T |
probably benign |
Het |
| Lipo3 |
C |
T |
19: 33,598,360 (GRCm39) |
|
probably benign |
Het |
| Lrrc3 |
G |
T |
10: 77,729,866 (GRCm39) |
|
probably benign |
Het |
| Ltbp3 |
T |
A |
19: 5,798,814 (GRCm39) |
|
probably null |
Het |
| Lyg1 |
T |
A |
1: 37,985,942 (GRCm39) |
|
probably benign |
Het |
| Mcm9 |
T |
C |
10: 53,424,623 (GRCm39) |
I656V |
probably benign |
Het |
| Mfsd8 |
T |
A |
3: 40,776,372 (GRCm39) |
I427F |
probably benign |
Het |
| Mga |
T |
A |
2: 119,769,104 (GRCm39) |
|
probably benign |
Het |
| Miga1 |
A |
G |
3: 151,993,155 (GRCm39) |
L422P |
probably damaging |
Het |
| Msantd3 |
A |
G |
4: 48,552,536 (GRCm39) |
I42V |
probably benign |
Het |
| Mybbp1a |
T |
C |
11: 72,336,538 (GRCm39) |
V510A |
probably benign |
Het |
| Nccrp1 |
G |
T |
7: 28,245,760 (GRCm39) |
P135T |
probably damaging |
Het |
| Neb |
T |
A |
2: 52,145,600 (GRCm39) |
M2975L |
possibly damaging |
Het |
| Nfxl1 |
A |
T |
5: 72,710,011 (GRCm39) |
I171N |
probably damaging |
Het |
| Odad2 |
A |
G |
18: 7,211,609 (GRCm39) |
V755A |
possibly damaging |
Het |
| Or10q3 |
T |
C |
19: 11,848,412 (GRCm39) |
H56R |
possibly damaging |
Het |
| Or12j5 |
A |
T |
7: 140,083,933 (GRCm39) |
F146L |
probably benign |
Het |
| Or13a19 |
T |
C |
7: 139,903,325 (GRCm39) |
F238L |
possibly damaging |
Het |
| Otop1 |
T |
G |
5: 38,457,368 (GRCm39) |
S376A |
possibly damaging |
Het |
| Pdgfra |
T |
C |
5: 75,322,932 (GRCm39) |
V10A |
possibly damaging |
Het |
| Pgs1 |
T |
C |
11: 117,910,503 (GRCm39) |
V538A |
probably damaging |
Het |
| Ppa2 |
A |
T |
3: 133,032,445 (GRCm39) |
T97S |
probably damaging |
Het |
| Pramel22 |
T |
A |
4: 143,380,847 (GRCm39) |
Y392F |
probably benign |
Het |
| Pramel26 |
A |
G |
4: 143,538,435 (GRCm39) |
S179P |
probably benign |
Het |
| Prdm10 |
G |
A |
9: 31,238,624 (GRCm39) |
C172Y |
probably damaging |
Het |
| Prrc2c |
G |
A |
1: 162,508,464 (GRCm39) |
P1091L |
probably damaging |
Het |
| Pthlh |
G |
A |
6: 147,158,796 (GRCm39) |
R55C |
probably damaging |
Het |
| Ptpn9 |
A |
T |
9: 56,943,782 (GRCm39) |
T105S |
probably benign |
Het |
| Rundc1 |
T |
A |
11: 101,324,830 (GRCm39) |
V512E |
possibly damaging |
Het |
| Scrib |
G |
A |
15: 75,937,185 (GRCm39) |
S307L |
probably damaging |
Het |
| Sec23ip |
A |
G |
7: 128,352,010 (GRCm39) |
S26G |
probably null |
Het |
| Sec61a2 |
A |
G |
2: 5,878,504 (GRCm39) |
|
probably benign |
Het |
| Sema3c |
T |
C |
5: 17,877,511 (GRCm39) |
V206A |
probably damaging |
Het |
| Sgk2 |
C |
T |
2: 162,839,763 (GRCm39) |
H124Y |
possibly damaging |
Het |
| Slc26a6 |
C |
T |
9: 108,738,540 (GRCm39) |
T592I |
probably damaging |
Het |
| Slc5a11 |
T |
C |
7: 122,864,486 (GRCm39) |
Y361H |
probably damaging |
Het |
| Smc6 |
T |
C |
12: 11,324,008 (GRCm39) |
V51A |
probably damaging |
Het |
| Stab1 |
A |
T |
14: 30,876,872 (GRCm39) |
N817K |
possibly damaging |
Het |
| Swt1 |
A |
T |
1: 151,283,348 (GRCm39) |
D336E |
probably benign |
Het |
| Taf13 |
T |
A |
3: 108,480,293 (GRCm39) |
|
probably benign |
Het |
| Tmub2 |
T |
C |
11: 102,175,845 (GRCm39) |
|
probably benign |
Het |
| Tnf |
A |
G |
17: 35,419,156 (GRCm39) |
S209P |
probably benign |
Het |
| Try10 |
A |
G |
6: 41,334,761 (GRCm39) |
Y229C |
probably damaging |
Het |
| Ttbk1 |
G |
T |
17: 46,788,714 (GRCm39) |
Y183* |
probably null |
Het |
| Ttc17 |
A |
T |
2: 94,194,774 (GRCm39) |
I533N |
possibly damaging |
Het |
| Tubb6 |
C |
T |
18: 67,535,016 (GRCm39) |
P305L |
probably damaging |
Het |
| Tulp3 |
G |
A |
6: 128,300,017 (GRCm39) |
|
probably benign |
Het |
| Usp9x |
A |
G |
X: 12,989,747 (GRCm39) |
R776G |
possibly damaging |
Het |
| Virma |
T |
C |
4: 11,513,505 (GRCm39) |
V453A |
probably damaging |
Het |
| Vmn2r103 |
A |
T |
17: 20,032,077 (GRCm39) |
N617I |
probably damaging |
Het |
| Xirp1 |
G |
T |
9: 119,846,058 (GRCm39) |
L942M |
probably damaging |
Het |
| Zc3h7b |
T |
G |
15: 81,676,451 (GRCm39) |
V731G |
probably benign |
Het |
| Zfp534 |
C |
T |
4: 147,759,175 (GRCm39) |
G498D |
probably benign |
Het |
| Zfp639 |
T |
C |
3: 32,574,679 (GRCm39) |
Y435H |
probably damaging |
Het |
| Zxdc |
A |
G |
6: 90,355,820 (GRCm39) |
H443R |
probably damaging |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACAGATTCTCCGGTGTTTGC -3'
(R):5'- CTTCAGCCAAGTAGGACAATTC -3'
Sequencing Primer
(F):5'- GTTTGCCTTGAGTAAGAAACCCGC -3'
(R):5'- ACAATTCCTCTTGGGCGG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation