Incidental Mutation 'R4717:Cemip'
| ID |
354130 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cemip
|
| Ensembl Gene |
ENSMUSG00000052353 |
| Gene Name |
cell migration inducing protein, hyaluronan binding |
| Synonyms |
12H19.01.T7, 6330404C01Rik, 9930013L23Rik, Hybid |
| MMRRC Submission |
041984-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.068)
|
| Stock # |
R4717 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
83582065-83735710 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 83596488 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 1092
(I1092N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000063277
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064174]
|
| AlphaFold |
Q8BI06 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000064174
AA Change: I1092N
PolyPhen 2
Score 0.973 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000063277
Gene: ENSMUSG00000052353
AA Change: I1092N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
G8
|
44 |
166 |
9.01e-42 |
SMART |
|
Pfam:ILEI
|
187 |
281 |
2.1e-28 |
PFAM |
|
Pfam:Mucin2_WxxW
|
324 |
403 |
1.2e-13 |
PFAM |
|
PbH1
|
572 |
594 |
7.34e3 |
SMART |
|
PbH1
|
595 |
617 |
3.73e3 |
SMART |
|
PbH1
|
719 |
741 |
4.11e3 |
SMART |
|
PbH1
|
798 |
819 |
6.96e2 |
SMART |
|
Blast:PbH1
|
844 |
882 |
7e-17 |
BLAST |
|
Blast:PbH1
|
917 |
952 |
2e-15 |
BLAST |
|
Pfam:ILEI
|
1244 |
1334 |
2.7e-17 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142518
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145171
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150495
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a conditional allele activated in Schwann cells exhibit transient acceleration of postnatal myelination, reduced demyelination in culture, and reduced myelin degradation and increases remyelination following nerve axotomy or sciatic nerve crush. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9330159F19Rik |
T |
C |
10: 29,097,783 (GRCm39) |
L60P |
probably damaging |
Het |
| Acsf2 |
T |
G |
11: 94,450,372 (GRCm39) |
M512L |
probably benign |
Het |
| Ahrr |
T |
A |
13: 74,363,885 (GRCm39) |
H312L |
probably benign |
Het |
| Akr1c18 |
T |
C |
13: 4,186,717 (GRCm39) |
M244V |
probably benign |
Het |
| Aldh3b2 |
A |
G |
19: 4,031,128 (GRCm39) |
Y459C |
probably damaging |
Het |
| Arhgap29 |
A |
T |
3: 121,803,607 (GRCm39) |
I796L |
possibly damaging |
Het |
| Arrdc4 |
T |
A |
7: 68,391,406 (GRCm39) |
D287V |
probably damaging |
Het |
| Astn2 |
A |
T |
4: 65,562,991 (GRCm39) |
I930N |
possibly damaging |
Het |
| Bace2 |
T |
A |
16: 97,238,073 (GRCm39) |
L508Q |
probably damaging |
Het |
| Baz2a |
G |
T |
10: 127,960,811 (GRCm39) |
C1537F |
possibly damaging |
Het |
| Cad |
A |
G |
5: 31,224,030 (GRCm39) |
|
probably null |
Het |
| Capn5 |
A |
T |
7: 97,773,126 (GRCm39) |
I626N |
probably benign |
Het |
| Car8 |
A |
T |
4: 8,169,685 (GRCm39) |
N274K |
probably damaging |
Het |
| Casp14 |
T |
C |
10: 78,550,958 (GRCm39) |
I76V |
probably benign |
Het |
| Ccdc88c |
A |
G |
12: 100,882,925 (GRCm39) |
V1649A |
probably benign |
Het |
| Clspn |
A |
G |
4: 126,453,849 (GRCm39) |
N91D |
probably damaging |
Het |
| Cpxm2 |
A |
G |
7: 131,656,574 (GRCm39) |
Y563H |
possibly damaging |
Het |
| Csnk1g2 |
T |
C |
10: 80,473,749 (GRCm39) |
V72A |
probably benign |
Het |
| Cyp46a1 |
T |
C |
12: 108,318,285 (GRCm39) |
|
probably null |
Het |
| Cyp4x1 |
T |
C |
4: 114,978,902 (GRCm39) |
H206R |
probably benign |
Het |
| Dapk1 |
T |
A |
13: 60,874,476 (GRCm39) |
|
probably null |
Het |
| Ddx1 |
A |
G |
12: 13,290,888 (GRCm39) |
W76R |
probably damaging |
Het |
| Dhx29 |
G |
A |
13: 113,083,469 (GRCm39) |
R508H |
unknown |
Het |
| Dnah2 |
T |
C |
11: 69,320,183 (GRCm39) |
D3962G |
probably benign |
Het |
| Dnajc14 |
T |
A |
10: 128,642,113 (GRCm39) |
C12S |
possibly damaging |
Het |
| Dock1 |
T |
C |
7: 134,449,899 (GRCm39) |
I804T |
probably damaging |
Het |
| Efs |
G |
T |
14: 55,157,801 (GRCm39) |
S170Y |
probably damaging |
Het |
| Eml4 |
G |
T |
17: 83,755,654 (GRCm39) |
W295C |
probably benign |
Het |
| Fkbp15 |
A |
G |
4: 62,226,306 (GRCm39) |
S748P |
probably damaging |
Het |
| Ghr |
T |
G |
15: 3,349,235 (GRCm39) |
I648L |
possibly damaging |
Het |
| Gigyf1 |
T |
A |
5: 137,523,494 (GRCm39) |
I942N |
probably damaging |
Het |
| Gpam |
T |
A |
19: 55,064,046 (GRCm39) |
E682D |
probably benign |
Het |
| Gsr |
A |
T |
8: 34,183,886 (GRCm39) |
K383* |
probably null |
Het |
| Hapln1 |
C |
A |
13: 89,753,579 (GRCm39) |
S248R |
probably benign |
Het |
| Haus2 |
G |
T |
2: 120,449,583 (GRCm39) |
R209L |
probably benign |
Het |
| Hhatl |
A |
G |
9: 121,618,943 (GRCm39) |
F63S |
probably damaging |
Het |
| Hmcn1 |
A |
G |
1: 150,494,816 (GRCm39) |
M4091T |
probably benign |
Het |
| Hspb7 |
A |
G |
4: 141,149,896 (GRCm39) |
D94G |
probably damaging |
Het |
| Irf6 |
T |
A |
1: 192,849,742 (GRCm39) |
|
probably null |
Het |
| Itgb2 |
T |
A |
10: 77,381,878 (GRCm39) |
L60* |
probably null |
Het |
| Jmjd1c |
C |
T |
10: 66,993,830 (GRCm39) |
Q104* |
probably null |
Het |
| Kcnh1 |
A |
G |
1: 191,959,025 (GRCm39) |
D193G |
probably damaging |
Het |
| Klhl25 |
G |
T |
7: 75,516,528 (GRCm39) |
C478F |
probably damaging |
Het |
| Klhl3 |
T |
C |
13: 58,178,330 (GRCm39) |
D267G |
probably damaging |
Het |
| L3mbtl4 |
T |
G |
17: 68,762,708 (GRCm39) |
H80Q |
probably null |
Het |
| Lhcgr |
C |
A |
17: 89,049,895 (GRCm39) |
V544F |
probably benign |
Het |
| Mfsd4a |
T |
C |
1: 131,985,633 (GRCm39) |
N168D |
probably benign |
Het |
| Mmp3 |
A |
G |
9: 7,449,881 (GRCm39) |
Q255R |
possibly damaging |
Het |
| Mrgprb3 |
C |
A |
7: 48,293,000 (GRCm39) |
G184C |
probably benign |
Het |
| Mtpap |
C |
T |
18: 4,396,394 (GRCm39) |
A562V |
possibly damaging |
Het |
| Nid1 |
T |
C |
13: 13,681,086 (GRCm39) |
V1072A |
probably benign |
Het |
| Nsf |
T |
G |
11: 103,714,595 (GRCm39) |
K728T |
probably damaging |
Het |
| Or10ak7 |
T |
C |
4: 118,791,626 (GRCm39) |
N140D |
probably benign |
Het |
| Or12j3 |
T |
C |
7: 139,953,328 (GRCm39) |
N65S |
probably damaging |
Het |
| Or1e17 |
T |
A |
11: 73,831,641 (GRCm39) |
S190T |
possibly damaging |
Het |
| Or2a5 |
T |
C |
6: 42,874,158 (GRCm39) |
Y258H |
probably damaging |
Het |
| Or4k15b |
A |
T |
14: 50,272,821 (GRCm39) |
V13E |
probably damaging |
Het |
| Pcsk5 |
A |
T |
19: 17,502,631 (GRCm39) |
C894S |
probably damaging |
Het |
| Pde2a |
A |
G |
7: 101,143,879 (GRCm39) |
D166G |
probably benign |
Het |
| Pfpl |
G |
A |
19: 12,406,618 (GRCm39) |
E290K |
probably benign |
Het |
| Pi4kb |
A |
C |
3: 94,906,162 (GRCm39) |
I570L |
probably damaging |
Het |
| Plxnb2 |
A |
T |
15: 89,041,622 (GRCm39) |
C1727* |
probably null |
Het |
| Poln |
A |
T |
5: 34,286,792 (GRCm39) |
D125E |
possibly damaging |
Het |
| Pomgnt1 |
A |
G |
4: 116,011,412 (GRCm39) |
D259G |
possibly damaging |
Het |
| Prx |
A |
T |
7: 27,216,152 (GRCm39) |
M218L |
probably benign |
Het |
| Pxn |
A |
T |
5: 115,690,001 (GRCm39) |
Q342L |
probably damaging |
Het |
| Rhpn2 |
A |
G |
7: 35,033,775 (GRCm39) |
D3G |
possibly damaging |
Het |
| Rnase2b |
C |
T |
14: 51,400,174 (GRCm39) |
T85I |
possibly damaging |
Het |
| Rnaseh2b |
C |
A |
14: 62,591,075 (GRCm39) |
T142K |
probably damaging |
Het |
| Sacs |
T |
C |
14: 61,450,304 (GRCm39) |
S4117P |
probably damaging |
Het |
| Sdk2 |
T |
C |
11: 113,745,195 (GRCm39) |
N700S |
probably damaging |
Het |
| Sec62 |
A |
C |
3: 30,864,020 (GRCm39) |
K101Q |
unknown |
Het |
| Sel1l2 |
A |
C |
2: 140,071,943 (GRCm39) |
L659R |
possibly damaging |
Het |
| Septin11 |
A |
G |
5: 93,304,815 (GRCm39) |
I211V |
possibly damaging |
Het |
| Slc25a42 |
C |
T |
8: 70,642,107 (GRCm39) |
E112K |
probably damaging |
Het |
| Spem2 |
T |
C |
11: 69,708,609 (GRCm39) |
N119D |
probably benign |
Het |
| Themis |
G |
A |
10: 28,665,748 (GRCm39) |
E604K |
probably benign |
Het |
| Tie1 |
T |
C |
4: 118,343,414 (GRCm39) |
K150E |
probably damaging |
Het |
| Top6bl |
A |
G |
19: 4,675,901 (GRCm39) |
|
probably benign |
Het |
| Ubap2 |
G |
A |
4: 41,218,333 (GRCm39) |
T258I |
possibly damaging |
Het |
| Ushbp1 |
C |
T |
8: 71,838,313 (GRCm39) |
A664T |
probably damaging |
Het |
| Vmn1r1 |
T |
C |
1: 181,984,774 (GRCm39) |
N297S |
possibly damaging |
Het |
| Vmn1r173 |
A |
C |
7: 23,402,637 (GRCm39) |
I291L |
probably damaging |
Het |
| Yy1 |
A |
G |
12: 108,759,972 (GRCm39) |
I212V |
possibly damaging |
Het |
| Zfp442 |
A |
T |
2: 150,250,149 (GRCm39) |
F527L |
probably damaging |
Het |
| Zyg11b |
T |
A |
4: 108,099,069 (GRCm39) |
H632L |
probably damaging |
Het |
|
| Other mutations in Cemip |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00781:Cemip
|
APN |
7 |
83,596,488 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL01520:Cemip
|
APN |
7 |
83,597,830 (GRCm39) |
missense |
probably benign |
0.27 |
|
IGL01646:Cemip
|
APN |
7 |
83,632,440 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02057:Cemip
|
APN |
7 |
83,636,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02058:Cemip
|
APN |
7 |
83,646,500 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02120:Cemip
|
APN |
7 |
83,600,771 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02278:Cemip
|
APN |
7 |
83,586,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Cemip
|
APN |
7 |
83,613,192 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02366:Cemip
|
APN |
7 |
83,592,849 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL02434:Cemip
|
APN |
7 |
83,604,492 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02622:Cemip
|
APN |
7 |
83,613,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02958:Cemip
|
APN |
7 |
83,624,263 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02979:Cemip
|
APN |
7 |
83,652,514 (GRCm39) |
splice site |
probably benign |
|
|
IGL03280:Cemip
|
APN |
7 |
83,636,538 (GRCm39) |
splice site |
probably benign |
|
|
IGL03400:Cemip
|
APN |
7 |
83,607,724 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03134:Cemip
|
UTSW |
7 |
83,648,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4618001:Cemip
|
UTSW |
7 |
83,593,147 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0149:Cemip
|
UTSW |
7 |
83,613,218 (GRCm39) |
missense |
probably benign |
|
|
R0212:Cemip
|
UTSW |
7 |
83,622,398 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0361:Cemip
|
UTSW |
7 |
83,613,218 (GRCm39) |
missense |
probably benign |
|
|
R0565:Cemip
|
UTSW |
7 |
83,613,318 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0727:Cemip
|
UTSW |
7 |
83,610,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1342:Cemip
|
UTSW |
7 |
83,593,283 (GRCm39) |
nonsense |
probably null |
|
|
R1456:Cemip
|
UTSW |
7 |
83,647,718 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1526:Cemip
|
UTSW |
7 |
83,600,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1676:Cemip
|
UTSW |
7 |
83,613,246 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1718:Cemip
|
UTSW |
7 |
83,584,866 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2234:Cemip
|
UTSW |
7 |
83,647,770 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2513:Cemip
|
UTSW |
7 |
83,591,233 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3788:Cemip
|
UTSW |
7 |
83,593,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3964:Cemip
|
UTSW |
7 |
83,600,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R3966:Cemip
|
UTSW |
7 |
83,600,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4436:Cemip
|
UTSW |
7 |
83,636,637 (GRCm39) |
missense |
probably null |
0.43 |
|
R4584:Cemip
|
UTSW |
7 |
83,607,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4601:Cemip
|
UTSW |
7 |
83,600,826 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4767:Cemip
|
UTSW |
7 |
83,622,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4822:Cemip
|
UTSW |
7 |
83,622,449 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4849:Cemip
|
UTSW |
7 |
83,584,945 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4910:Cemip
|
UTSW |
7 |
83,646,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4911:Cemip
|
UTSW |
7 |
83,632,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4922:Cemip
|
UTSW |
7 |
83,596,308 (GRCm39) |
intron |
probably benign |
|
|
R4924:Cemip
|
UTSW |
7 |
83,602,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Cemip
|
UTSW |
7 |
83,591,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5310:Cemip
|
UTSW |
7 |
83,641,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5327:Cemip
|
UTSW |
7 |
83,604,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5378:Cemip
|
UTSW |
7 |
83,607,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Cemip
|
UTSW |
7 |
83,631,499 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5644:Cemip
|
UTSW |
7 |
83,638,392 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5688:Cemip
|
UTSW |
7 |
83,610,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5714:Cemip
|
UTSW |
7 |
83,624,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6170:Cemip
|
UTSW |
7 |
83,596,438 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6505:Cemip
|
UTSW |
7 |
83,600,805 (GRCm39) |
nonsense |
probably null |
|
|
R6713:Cemip
|
UTSW |
7 |
83,592,845 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6767:Cemip
|
UTSW |
7 |
83,647,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6817:Cemip
|
UTSW |
7 |
83,637,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6896:Cemip
|
UTSW |
7 |
83,647,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6945:Cemip
|
UTSW |
7 |
83,647,755 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7236:Cemip
|
UTSW |
7 |
83,598,012 (GRCm39) |
splice site |
probably null |
|
|
R7410:Cemip
|
UTSW |
7 |
83,602,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Cemip
|
UTSW |
7 |
83,647,784 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Cemip
|
UTSW |
7 |
83,606,872 (GRCm39) |
nonsense |
probably null |
|
|
R7924:Cemip
|
UTSW |
7 |
83,592,923 (GRCm39) |
splice site |
probably benign |
|
|
R7962:Cemip
|
UTSW |
7 |
83,652,616 (GRCm39) |
start gained |
probably benign |
|
|
R7988:Cemip
|
UTSW |
7 |
83,652,616 (GRCm39) |
start gained |
probably benign |
|
|
R7993:Cemip
|
UTSW |
7 |
83,613,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Cemip
|
UTSW |
7 |
83,652,616 (GRCm39) |
start gained |
probably benign |
|
|
R8077:Cemip
|
UTSW |
7 |
83,652,616 (GRCm39) |
start gained |
probably benign |
|
|
R8130:Cemip
|
UTSW |
7 |
83,596,384 (GRCm39) |
missense |
probably benign |
|
|
R8131:Cemip
|
UTSW |
7 |
83,652,616 (GRCm39) |
start gained |
probably benign |
|
|
R8172:Cemip
|
UTSW |
7 |
83,646,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8220:Cemip
|
UTSW |
7 |
83,596,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8345:Cemip
|
UTSW |
7 |
83,591,373 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8391:Cemip
|
UTSW |
7 |
83,604,517 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8492:Cemip
|
UTSW |
7 |
83,622,422 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8496:Cemip
|
UTSW |
7 |
83,600,634 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8698:Cemip
|
UTSW |
7 |
83,607,790 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8835:Cemip
|
UTSW |
7 |
83,586,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9229:Cemip
|
UTSW |
7 |
83,606,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Cemip
|
UTSW |
7 |
83,610,843 (GRCm39) |
missense |
probably damaging |
0.99 |
|
T0970:Cemip
|
UTSW |
7 |
83,632,354 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0067:Cemip
|
UTSW |
7 |
83,596,416 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Cemip
|
UTSW |
7 |
83,596,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACTGCACTGCACTTCTTAGGG -3'
(R):5'- CTCCCTGAACACTTTGCAACATAG -3'
Sequencing Primer
(F):5'- GCACTTCTTAGGGTTATAGGGAAAC -3'
(R):5'- GCCCTTGCCTAGAACTAA -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation