Incidental Mutation 'R4718:N4bp2'
| ID |
354205 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
N4bp2
|
| Ensembl Gene |
ENSMUSG00000037795 |
| Gene Name |
NEDD4 binding protein 2 |
| Synonyms |
LOC333789, B3bp, LOC386488 |
| MMRRC Submission |
041985-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.190)
|
| Stock # |
R4718 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
65920864-65987451 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 65960806 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Isoleucine
at position 492
(M492I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144278
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087264]
[ENSMUST00000201489]
[ENSMUST00000201615]
|
| AlphaFold |
F8VQG7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000087264
AA Change: M492I
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000084519
Gene: ENSMUSG00000037795
AA Change: M492I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.1e-15 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200843
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000201489
AA Change: M492I
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000143807
Gene: ENSMUSG00000037795
AA Change: M492I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000201615
AA Change: M492I
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000144278
Gene: ENSMUSG00000037795
AA Change: M492I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.2e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
8e-10 |
BLAST |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
|
| Allele List at MGI |
All alleles(9) : Targeted, other(2) Gene trapped(7)
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930519G04Rik |
G |
A |
5: 115,001,615 (GRCm39) |
|
probably null |
Het |
| Acsm2 |
A |
T |
7: 119,172,826 (GRCm39) |
Y147F |
probably damaging |
Het |
| Alg12 |
A |
T |
15: 88,690,256 (GRCm39) |
Y413N |
probably damaging |
Het |
| Arrdc3 |
A |
T |
13: 81,031,986 (GRCm39) |
Q73L |
possibly damaging |
Het |
| Atp13a5 |
T |
C |
16: 29,066,922 (GRCm39) |
K1017E |
probably damaging |
Het |
| Bmal1 |
A |
T |
7: 112,902,568 (GRCm39) |
I399F |
probably damaging |
Het |
| Bms1 |
T |
C |
6: 118,380,196 (GRCm39) |
N704D |
possibly damaging |
Het |
| Bsph1 |
T |
A |
7: 13,206,107 (GRCm39) |
Y47* |
probably null |
Het |
| Crat |
A |
T |
2: 30,298,176 (GRCm39) |
Y174* |
probably null |
Het |
| Csmd3 |
G |
T |
15: 47,561,546 (GRCm39) |
Y2254* |
probably null |
Het |
| Cyld |
T |
A |
8: 89,468,933 (GRCm39) |
I568N |
probably damaging |
Het |
| Dapl1 |
T |
C |
2: 59,315,072 (GRCm39) |
V7A |
probably benign |
Het |
| Dhx29 |
G |
A |
13: 113,083,469 (GRCm39) |
R508H |
unknown |
Het |
| Dnah9 |
A |
G |
11: 65,976,299 (GRCm39) |
I1250T |
probably benign |
Het |
| Dnajb3 |
C |
T |
1: 88,133,061 (GRCm39) |
D114N |
probably benign |
Het |
| Dsg1b |
A |
G |
18: 20,530,986 (GRCm39) |
N446D |
probably damaging |
Het |
| Dthd1 |
T |
A |
5: 62,976,136 (GRCm39) |
V270E |
probably damaging |
Het |
| F2rl3 |
A |
C |
8: 73,489,536 (GRCm39) |
R254S |
possibly damaging |
Het |
| Fgfr2 |
A |
G |
7: 129,863,518 (GRCm39) |
S24P |
probably damaging |
Het |
| Fpr2 |
T |
C |
17: 18,113,598 (GRCm39) |
V198A |
probably benign |
Het |
| Gbp2b |
G |
A |
3: 142,304,756 (GRCm39) |
G64D |
probably damaging |
Het |
| Gbp9 |
T |
G |
5: 105,231,624 (GRCm39) |
N321H |
probably damaging |
Het |
| Gk2 |
T |
A |
5: 97,603,725 (GRCm39) |
Y371F |
probably benign |
Het |
| Gm10382 |
T |
C |
5: 125,466,462 (GRCm39) |
|
probably benign |
Het |
| Gpatch3 |
A |
G |
4: 133,309,855 (GRCm39) |
D396G |
probably benign |
Het |
| Heatr5a |
A |
C |
12: 51,962,946 (GRCm39) |
L985V |
possibly damaging |
Het |
| Homer1 |
T |
A |
13: 93,528,272 (GRCm39) |
V269E |
probably damaging |
Het |
| Hspbap1 |
T |
C |
16: 35,607,692 (GRCm39) |
V66A |
probably benign |
Het |
| Ighv7-2 |
A |
C |
12: 113,876,089 (GRCm39) |
I5M |
possibly damaging |
Het |
| Ints7 |
T |
A |
1: 191,315,389 (GRCm39) |
F108Y |
possibly damaging |
Het |
| Itga7 |
CT |
CTGGGGATT |
10: 128,776,603 (GRCm39) |
|
probably null |
Het |
| Junb |
G |
A |
8: 85,705,061 (GRCm39) |
|
probably benign |
Het |
| Lcp2 |
A |
G |
11: 34,020,992 (GRCm39) |
N116S |
probably benign |
Het |
| Lrguk |
A |
G |
6: 34,006,431 (GRCm39) |
T14A |
probably benign |
Het |
| Lrrcc1 |
T |
A |
3: 14,601,092 (GRCm39) |
H41Q |
probably damaging |
Het |
| Ltb |
C |
A |
17: 35,414,313 (GRCm39) |
|
probably null |
Het |
| Mapk7 |
A |
G |
11: 61,380,080 (GRCm39) |
S693P |
possibly damaging |
Het |
| Mbd5 |
A |
T |
2: 49,146,414 (GRCm39) |
H208L |
possibly damaging |
Het |
| Megf9 |
A |
T |
4: 70,367,015 (GRCm39) |
S322R |
possibly damaging |
Het |
| Mgat4c |
T |
C |
10: 102,224,467 (GRCm39) |
V227A |
probably damaging |
Het |
| Mospd3 |
G |
A |
5: 137,597,915 (GRCm39) |
T151M |
probably benign |
Het |
| Mpl |
A |
G |
4: 118,313,921 (GRCm39) |
S115P |
probably benign |
Het |
| Myo6 |
C |
A |
9: 80,153,799 (GRCm39) |
D258E |
probably benign |
Het |
| Ndst3 |
G |
A |
3: 123,465,915 (GRCm39) |
A19V |
probably benign |
Het |
| Nkx2-3 |
C |
A |
19: 43,601,082 (GRCm39) |
T48K |
probably benign |
Het |
| Nlrp4f |
T |
C |
13: 65,342,803 (GRCm39) |
T281A |
probably benign |
Het |
| Nmur1 |
A |
G |
1: 86,315,463 (GRCm39) |
V157A |
probably damaging |
Het |
| Obscn |
A |
T |
11: 58,912,780 (GRCm39) |
F6992L |
probably damaging |
Het |
| Ocm |
G |
T |
5: 143,961,375 (GRCm39) |
P22Q |
possibly damaging |
Het |
| Or5be3 |
T |
C |
2: 86,864,239 (GRCm39) |
T109A |
probably damaging |
Het |
| Osbp2 |
C |
A |
11: 3,661,793 (GRCm39) |
C753F |
probably damaging |
Het |
| Pabpc2 |
A |
G |
18: 39,907,556 (GRCm39) |
T274A |
probably benign |
Het |
| Pamr1 |
T |
A |
2: 102,472,681 (GRCm39) |
I660N |
probably damaging |
Het |
| Papola |
C |
T |
12: 105,786,707 (GRCm39) |
T466I |
possibly damaging |
Het |
| Pask |
T |
C |
1: 93,249,918 (GRCm39) |
E494G |
possibly damaging |
Het |
| Pck1 |
A |
T |
2: 172,997,014 (GRCm39) |
I219F |
probably damaging |
Het |
| Pgm3 |
T |
C |
9: 86,452,448 (GRCm39) |
E4G |
probably benign |
Het |
| Pgs1 |
A |
G |
11: 117,896,709 (GRCm39) |
H462R |
probably damaging |
Het |
| Phlpp2 |
T |
A |
8: 110,667,452 (GRCm39) |
M1327K |
probably benign |
Het |
| Pkhd1 |
C |
A |
1: 20,151,452 (GRCm39) |
G3815W |
probably damaging |
Het |
| Plin4 |
T |
A |
17: 56,413,981 (GRCm39) |
I215F |
possibly damaging |
Het |
| Plod1 |
T |
G |
4: 148,000,701 (GRCm39) |
|
probably benign |
Het |
| Ppfia2 |
T |
C |
10: 106,694,146 (GRCm39) |
S707P |
probably damaging |
Het |
| Psmd12 |
A |
G |
11: 107,377,259 (GRCm39) |
Q86R |
probably benign |
Het |
| Rasgrf2 |
C |
A |
13: 92,138,716 (GRCm39) |
|
probably null |
Het |
| Rictor |
T |
C |
15: 6,812,641 (GRCm39) |
S926P |
possibly damaging |
Het |
| Rras2 |
A |
T |
7: 113,649,584 (GRCm39) |
I160N |
probably benign |
Het |
| Slc27a6 |
A |
T |
18: 58,738,138 (GRCm39) |
Y398F |
probably benign |
Het |
| Speer4f1 |
A |
G |
5: 17,685,422 (GRCm39) |
E239G |
unknown |
Het |
| Sppl2c |
T |
C |
11: 104,079,141 (GRCm39) |
I647T |
probably benign |
Het |
| Sptan1 |
A |
G |
2: 29,921,074 (GRCm39) |
Y2467C |
probably damaging |
Het |
| Sptbn1 |
G |
T |
11: 30,104,297 (GRCm39) |
H136N |
probably damaging |
Het |
| Stau2 |
T |
C |
1: 16,416,269 (GRCm39) |
|
probably null |
Het |
| Tasor2 |
A |
T |
13: 3,624,495 (GRCm39) |
D1818E |
probably benign |
Het |
| Tet1 |
T |
A |
10: 62,649,591 (GRCm39) |
I40F |
probably damaging |
Het |
| Tnfaip2 |
A |
G |
12: 111,412,463 (GRCm39) |
E288G |
possibly damaging |
Het |
| Trav7-5 |
T |
A |
14: 53,768,610 (GRCm39) |
H59Q |
probably benign |
Het |
| Usp53 |
T |
C |
3: 122,727,631 (GRCm39) |
I984V |
probably benign |
Het |
| Wdfy4 |
A |
G |
14: 32,867,273 (GRCm39) |
I403T |
probably benign |
Het |
| Yars2 |
T |
A |
16: 16,127,204 (GRCm39) |
M423K |
probably benign |
Het |
| Zfp292 |
A |
T |
4: 34,819,521 (GRCm39) |
V272D |
possibly damaging |
Het |
| Zmynd11 |
A |
T |
13: 9,739,603 (GRCm39) |
V478D |
possibly damaging |
Het |
|
| Other mutations in N4bp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:N4bp2
|
APN |
5 |
65,964,867 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01503:N4bp2
|
APN |
5 |
65,960,890 (GRCm39) |
nonsense |
probably null |
0.00 |
|
IGL01621:N4bp2
|
APN |
5 |
65,948,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02109:N4bp2
|
APN |
5 |
65,955,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02286:N4bp2
|
APN |
5 |
65,960,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
1mM(1):N4bp2
|
UTSW |
5 |
65,965,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03046:N4bp2
|
UTSW |
5 |
65,948,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:N4bp2
|
UTSW |
5 |
65,960,916 (GRCm39) |
splice site |
probably benign |
|
|
R0285:N4bp2
|
UTSW |
5 |
65,963,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0366:N4bp2
|
UTSW |
5 |
65,963,739 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0548:N4bp2
|
UTSW |
5 |
65,965,496 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0551:N4bp2
|
UTSW |
5 |
65,977,684 (GRCm39) |
splice site |
probably null |
|
|
R0671:N4bp2
|
UTSW |
5 |
65,964,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1136:N4bp2
|
UTSW |
5 |
65,965,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:N4bp2
|
UTSW |
5 |
65,947,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1597:N4bp2
|
UTSW |
5 |
65,964,483 (GRCm39) |
missense |
probably benign |
0.45 |
|
R1628:N4bp2
|
UTSW |
5 |
65,960,915 (GRCm39) |
splice site |
probably null |
|
|
R1722:N4bp2
|
UTSW |
5 |
65,964,225 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1735:N4bp2
|
UTSW |
5 |
65,965,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:N4bp2
|
UTSW |
5 |
65,948,165 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1759:N4bp2
|
UTSW |
5 |
65,983,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1799:N4bp2
|
UTSW |
5 |
65,964,168 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1846:N4bp2
|
UTSW |
5 |
65,965,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1872:N4bp2
|
UTSW |
5 |
65,951,861 (GRCm39) |
splice site |
probably benign |
|
|
R2042:N4bp2
|
UTSW |
5 |
65,983,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2082:N4bp2
|
UTSW |
5 |
65,964,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:N4bp2
|
UTSW |
5 |
65,948,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:N4bp2
|
UTSW |
5 |
65,966,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2251:N4bp2
|
UTSW |
5 |
65,964,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2507:N4bp2
|
UTSW |
5 |
65,947,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2508:N4bp2
|
UTSW |
5 |
65,947,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2919:N4bp2
|
UTSW |
5 |
65,964,441 (GRCm39) |
missense |
probably benign |
0.22 |
|
R3086:N4bp2
|
UTSW |
5 |
65,948,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4092:N4bp2
|
UTSW |
5 |
65,947,799 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4177:N4bp2
|
UTSW |
5 |
65,955,513 (GRCm39) |
splice site |
probably null |
|
|
R4859:N4bp2
|
UTSW |
5 |
65,982,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:N4bp2
|
UTSW |
5 |
65,965,473 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4915:N4bp2
|
UTSW |
5 |
65,960,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4949:N4bp2
|
UTSW |
5 |
65,979,142 (GRCm39) |
splice site |
probably null |
|
|
R4978:N4bp2
|
UTSW |
5 |
65,947,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5029:N4bp2
|
UTSW |
5 |
65,972,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5079:N4bp2
|
UTSW |
5 |
65,969,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5097:N4bp2
|
UTSW |
5 |
65,974,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5158:N4bp2
|
UTSW |
5 |
65,965,805 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5228:N4bp2
|
UTSW |
5 |
65,964,861 (GRCm39) |
missense |
probably benign |
|
|
R5322:N4bp2
|
UTSW |
5 |
65,947,800 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5554:N4bp2
|
UTSW |
5 |
65,965,457 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5731:N4bp2
|
UTSW |
5 |
65,966,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:N4bp2
|
UTSW |
5 |
65,965,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6393:N4bp2
|
UTSW |
5 |
65,948,344 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6767:N4bp2
|
UTSW |
5 |
65,974,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7103:N4bp2
|
UTSW |
5 |
65,964,189 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7112:N4bp2
|
UTSW |
5 |
65,948,050 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7171:N4bp2
|
UTSW |
5 |
65,965,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7177:N4bp2
|
UTSW |
5 |
65,964,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7240:N4bp2
|
UTSW |
5 |
65,951,888 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7353:N4bp2
|
UTSW |
5 |
65,963,714 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7450:N4bp2
|
UTSW |
5 |
65,982,643 (GRCm39) |
nonsense |
probably null |
|
|
R7560:N4bp2
|
UTSW |
5 |
65,948,458 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7698:N4bp2
|
UTSW |
5 |
65,965,500 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7743:N4bp2
|
UTSW |
5 |
65,965,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7871:N4bp2
|
UTSW |
5 |
65,964,446 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7981:N4bp2
|
UTSW |
5 |
65,969,485 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8065:N4bp2
|
UTSW |
5 |
65,964,639 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8067:N4bp2
|
UTSW |
5 |
65,964,639 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8164:N4bp2
|
UTSW |
5 |
65,966,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8166:N4bp2
|
UTSW |
5 |
65,977,655 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8331:N4bp2
|
UTSW |
5 |
65,964,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8559:N4bp2
|
UTSW |
5 |
65,982,628 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8806:N4bp2
|
UTSW |
5 |
65,965,551 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9287:N4bp2
|
UTSW |
5 |
65,960,855 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9369:N4bp2
|
UTSW |
5 |
65,964,259 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9460:N4bp2
|
UTSW |
5 |
65,963,886 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9462:N4bp2
|
UTSW |
5 |
65,947,898 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9605:N4bp2
|
UTSW |
5 |
65,963,879 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9641:N4bp2
|
UTSW |
5 |
65,948,035 (GRCm39) |
missense |
probably benign |
0.15 |
|
Z1177:N4bp2
|
UTSW |
5 |
65,964,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCTCATGAGAAGTGCCAG -3'
(R):5'- GCTGACTTCAGGTGAAACTGATC -3'
Sequencing Primer
(F):5'- TCTCATGAGAAGTGCCAGTGATG -3'
(R):5'- GTCAGAAGCGTATGCACA -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation