Incidental Mutation 'R4701:Tnn'
| ID |
355992 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnn
|
| Ensembl Gene |
ENSMUSG00000026725 |
| Gene Name |
tenascin N |
| Synonyms |
tenascin-W, Tnw |
| MMRRC Submission |
041949-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.298)
|
| Stock # |
R4701 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
159912599-159981150 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 159975338 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 30
(S30T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039452
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039178]
[ENSMUST00000131919]
|
| AlphaFold |
Q80Z71 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000039178
AA Change: S30T
PolyPhen 2
Score 0.719 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000039452
Gene: ENSMUSG00000026725
AA Change: S30T
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.34e-9 |
SMART |
|
FN3
|
883 |
960 |
9.04e-9 |
SMART |
|
FN3
|
971 |
1048 |
1.07e-10 |
SMART |
|
FN3
|
1059 |
1136 |
7.57e-11 |
SMART |
|
FN3
|
1147 |
1224 |
4.59e-10 |
SMART |
|
FN3
|
1235 |
1312 |
1.95e-4 |
SMART |
|
FBG
|
1327 |
1539 |
1.16e-114 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131919
AA Change: S30T
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000115685
Gene: ENSMUSG00000026725
AA Change: S30T
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.57e-11 |
SMART |
|
FN3
|
883 |
960 |
4.59e-10 |
SMART |
|
FN3
|
971 |
1048 |
1.95e-4 |
SMART |
|
FBG
|
1063 |
1275 |
1.16e-114 |
SMART |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
96% (108/112) |
| Allele List at MGI |
All alleles(2) : Targeted, other(2)
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aarsd1 |
T |
C |
11: 101,301,986 (GRCm39) |
I196V |
probably benign |
Het |
| Aass |
T |
A |
6: 23,075,855 (GRCm39) |
K761* |
probably null |
Het |
| Abca13 |
A |
G |
11: 9,242,306 (GRCm39) |
T1390A |
possibly damaging |
Het |
| Abhd16a |
T |
C |
17: 35,315,582 (GRCm39) |
|
probably null |
Het |
| Acad11 |
C |
T |
9: 103,972,764 (GRCm39) |
Q486* |
probably null |
Het |
| Actl9 |
T |
C |
17: 33,652,909 (GRCm39) |
L323P |
probably benign |
Het |
| Adam12 |
T |
A |
7: 133,518,191 (GRCm39) |
I650F |
possibly damaging |
Het |
| Adgre4 |
A |
T |
17: 56,091,971 (GRCm39) |
D77V |
probably damaging |
Het |
| Ankrd26 |
A |
G |
6: 118,483,446 (GRCm39) |
F1586S |
possibly damaging |
Het |
| Anpep |
T |
C |
7: 79,489,213 (GRCm39) |
T320A |
probably benign |
Het |
| Arl15 |
T |
A |
13: 114,104,261 (GRCm39) |
C133S |
probably benign |
Het |
| Ascc3 |
A |
G |
10: 50,596,760 (GRCm39) |
N1230S |
possibly damaging |
Het |
| Atf4 |
T |
A |
15: 80,141,618 (GRCm39) |
I336K |
probably damaging |
Het |
| Atp7b |
A |
T |
8: 22,490,137 (GRCm39) |
S1044T |
probably benign |
Het |
| Atp8b4 |
A |
G |
2: 126,256,213 (GRCm39) |
F249L |
probably damaging |
Het |
| AU021092 |
G |
T |
16: 5,030,057 (GRCm39) |
N319K |
probably benign |
Het |
| Bbs4 |
A |
G |
9: 59,230,802 (GRCm39) |
V440A |
probably benign |
Het |
| Bpifb4 |
G |
T |
2: 153,792,305 (GRCm39) |
G450C |
probably damaging |
Het |
| Cadm1 |
G |
A |
9: 47,730,120 (GRCm39) |
|
probably benign |
Het |
| Ccser2 |
G |
A |
14: 36,660,654 (GRCm39) |
L500F |
probably damaging |
Het |
| Cd22 |
T |
A |
7: 30,575,578 (GRCm39) |
I155F |
probably damaging |
Het |
| Cdkl4 |
A |
T |
17: 80,851,081 (GRCm39) |
V207E |
probably damaging |
Het |
| Cfap251 |
A |
G |
5: 123,460,676 (GRCm39) |
K1213E |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,958,067 (GRCm39) |
D947G |
probably damaging |
Het |
| Cntn6 |
T |
C |
6: 104,781,321 (GRCm39) |
V397A |
probably benign |
Het |
| Cpox |
T |
A |
16: 58,498,332 (GRCm39) |
Y388* |
probably null |
Het |
| Dab1 |
C |
T |
4: 104,588,948 (GRCm39) |
A524V |
probably benign |
Het |
| Dda1 |
T |
A |
8: 71,926,454 (GRCm39) |
Y58N |
probably damaging |
Het |
| Dennd4a |
C |
T |
9: 64,804,639 (GRCm39) |
T1326I |
possibly damaging |
Het |
| Eps8l2 |
A |
T |
7: 140,937,173 (GRCm39) |
I338F |
probably damaging |
Het |
| Fbxo42 |
A |
G |
4: 140,927,120 (GRCm39) |
T467A |
probably benign |
Het |
| Flt4 |
T |
C |
11: 49,517,635 (GRCm39) |
F319S |
possibly damaging |
Het |
| Fmn1 |
A |
T |
2: 113,414,416 (GRCm39) |
Y895F |
possibly damaging |
Het |
| Gm6887 |
C |
A |
7: 42,114,517 (GRCm39) |
|
noncoding transcript |
Het |
| Grid2 |
A |
G |
6: 64,642,899 (GRCm39) |
D887G |
probably benign |
Het |
| Grm6 |
C |
T |
11: 50,753,837 (GRCm39) |
P714S |
probably damaging |
Het |
| Gsto2 |
A |
G |
19: 47,873,095 (GRCm39) |
I157V |
probably benign |
Het |
| Il15ra |
A |
G |
2: 11,723,156 (GRCm39) |
|
probably null |
Het |
| Impg1 |
A |
G |
9: 80,221,682 (GRCm39) |
F713L |
probably benign |
Het |
| Jag1 |
T |
A |
2: 136,936,376 (GRCm39) |
T373S |
probably benign |
Het |
| Kcnh3 |
T |
A |
15: 99,139,826 (GRCm39) |
L904Q |
probably benign |
Het |
| Kctd19 |
C |
A |
8: 106,117,061 (GRCm39) |
G356V |
possibly damaging |
Het |
| Kdm5b |
T |
A |
1: 134,533,750 (GRCm39) |
|
probably benign |
Het |
| Kif1a |
T |
C |
1: 93,006,557 (GRCm39) |
I37V |
probably damaging |
Het |
| Lama5 |
G |
A |
2: 179,833,489 (GRCm39) |
R1508C |
probably damaging |
Het |
| Lamb1 |
T |
A |
12: 31,316,847 (GRCm39) |
C65* |
probably null |
Het |
| Lingo1 |
A |
G |
9: 56,527,542 (GRCm39) |
F349S |
probably damaging |
Het |
| Loxl4 |
G |
A |
19: 42,596,052 (GRCm39) |
H147Y |
probably benign |
Het |
| Lrrn4cl |
T |
A |
19: 8,829,419 (GRCm39) |
N132K |
probably damaging |
Het |
| Med17 |
A |
T |
9: 15,181,656 (GRCm39) |
H31Q |
probably damaging |
Het |
| Med23 |
A |
T |
10: 24,769,546 (GRCm39) |
L476F |
probably damaging |
Het |
| Mgst1 |
A |
T |
6: 138,127,836 (GRCm39) |
D66V |
probably damaging |
Het |
| Mroh2a |
T |
C |
1: 88,162,334 (GRCm39) |
|
probably null |
Het |
| Mroh2a |
A |
C |
1: 88,169,340 (GRCm39) |
I672L |
probably benign |
Het |
| Muc4 |
A |
T |
16: 32,576,220 (GRCm39) |
|
probably benign |
Het |
| Myo18a |
C |
T |
11: 77,708,491 (GRCm39) |
T30M |
probably damaging |
Het |
| Ncapg2 |
G |
T |
12: 116,404,238 (GRCm39) |
R903L |
probably benign |
Het |
| Nme1 |
A |
G |
11: 93,856,734 (GRCm39) |
I9T |
probably damaging |
Het |
| Nmt2 |
T |
A |
2: 3,323,678 (GRCm39) |
I357N |
probably benign |
Het |
| Nphp4 |
T |
C |
4: 152,581,116 (GRCm39) |
F100S |
probably damaging |
Het |
| Oca2 |
C |
A |
7: 55,904,750 (GRCm39) |
T72K |
probably benign |
Het |
| Or52e4 |
A |
T |
7: 104,706,086 (GRCm39) |
D211V |
probably damaging |
Het |
| Or52e7 |
A |
T |
7: 104,684,798 (GRCm39) |
D131V |
probably damaging |
Het |
| Or52z15 |
G |
A |
7: 103,332,269 (GRCm39) |
V105M |
probably damaging |
Het |
| Or7h8 |
T |
C |
9: 20,123,921 (GRCm39) |
I92T |
probably damaging |
Het |
| Or9s15 |
C |
A |
1: 92,525,160 (GRCm39) |
D306E |
probably benign |
Het |
| Plce1 |
A |
T |
19: 38,713,451 (GRCm39) |
T1240S |
probably benign |
Het |
| Plch1 |
A |
T |
3: 63,606,917 (GRCm39) |
|
probably null |
Het |
| Plxna4 |
T |
C |
6: 32,493,623 (GRCm39) |
D331G |
probably damaging |
Het |
| Ppp1r3a |
T |
C |
6: 14,718,992 (GRCm39) |
T641A |
probably benign |
Het |
| Rab32 |
A |
G |
10: 10,426,598 (GRCm39) |
L116P |
probably benign |
Het |
| Recql4 |
C |
T |
15: 76,592,785 (GRCm39) |
C302Y |
probably damaging |
Het |
| Rorc |
G |
C |
3: 94,299,017 (GRCm39) |
E391Q |
probably null |
Het |
| Saa4 |
A |
T |
7: 46,381,051 (GRCm39) |
F24I |
possibly damaging |
Het |
| Sall1 |
T |
A |
8: 89,757,788 (GRCm39) |
K772M |
probably damaging |
Het |
| Sdk1 |
T |
G |
5: 142,170,986 (GRCm39) |
L1950V |
probably damaging |
Het |
| Sil1 |
T |
C |
18: 35,399,949 (GRCm39) |
E352G |
probably benign |
Het |
| Slc26a3 |
C |
T |
12: 31,497,773 (GRCm39) |
P59L |
probably damaging |
Het |
| Smco2 |
T |
C |
6: 146,763,440 (GRCm39) |
|
probably benign |
Het |
| Sppl3 |
A |
G |
5: 115,241,372 (GRCm39) |
|
probably null |
Het |
| St6gal2 |
T |
A |
17: 55,803,345 (GRCm39) |
V360D |
probably damaging |
Het |
| Stard9 |
G |
A |
2: 120,536,194 (GRCm39) |
R345Q |
possibly damaging |
Het |
| Susd4 |
T |
A |
1: 182,719,626 (GRCm39) |
Y414N |
probably damaging |
Het |
| Tenm4 |
T |
C |
7: 96,544,556 (GRCm39) |
Y2191H |
probably damaging |
Het |
| Tln2 |
A |
G |
9: 67,253,809 (GRCm39) |
V754A |
probably benign |
Het |
| Tmem132c |
T |
A |
5: 127,641,560 (GRCm39) |
|
probably benign |
Het |
| Trpd52l3 |
G |
T |
19: 29,981,895 (GRCm39) |
V217F |
probably damaging |
Het |
| Trpm1 |
G |
T |
7: 63,893,248 (GRCm39) |
L1033F |
probably damaging |
Het |
| Tulp2 |
A |
G |
7: 45,167,348 (GRCm39) |
E182G |
probably damaging |
Het |
| Ubr4 |
A |
G |
4: 139,198,647 (GRCm39) |
K4490R |
possibly damaging |
Het |
| Usp17la |
A |
T |
7: 104,509,856 (GRCm39) |
R154* |
probably null |
Het |
| Vmn2r17 |
T |
G |
5: 109,575,849 (GRCm39) |
M240R |
probably damaging |
Het |
| Vmn2r22 |
T |
A |
6: 123,627,428 (GRCm39) |
N56I |
probably benign |
Het |
| Zdhhc21 |
A |
T |
4: 82,738,571 (GRCm39) |
I206N |
possibly damaging |
Het |
| Zfp148 |
T |
A |
16: 33,277,278 (GRCm39) |
D122E |
probably benign |
Het |
| Zfp804a |
A |
T |
2: 82,086,926 (GRCm39) |
S252C |
probably damaging |
Het |
| Zgrf1 |
C |
T |
3: 127,392,353 (GRCm39) |
T1291I |
probably benign |
Het |
|
| Other mutations in Tnn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Tnn
|
APN |
1 |
159,953,021 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL00433:Tnn
|
APN |
1 |
159,925,776 (GRCm39) |
splice site |
probably benign |
|
|
IGL00858:Tnn
|
APN |
1 |
159,915,962 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00939:Tnn
|
APN |
1 |
159,975,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01569:Tnn
|
APN |
1 |
159,948,124 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01591:Tnn
|
APN |
1 |
159,953,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Tnn
|
APN |
1 |
159,975,172 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01811:Tnn
|
APN |
1 |
159,934,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01813:Tnn
|
APN |
1 |
159,916,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02340:Tnn
|
APN |
1 |
159,972,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Tnn
|
APN |
1 |
159,968,163 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL02535:Tnn
|
APN |
1 |
159,950,222 (GRCm39) |
splice site |
probably null |
|
|
IGL02563:Tnn
|
APN |
1 |
159,942,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02572:Tnn
|
APN |
1 |
159,913,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Tnn
|
APN |
1 |
159,968,347 (GRCm39) |
splice site |
probably benign |
|
|
IGL02818:Tnn
|
APN |
1 |
159,943,848 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03284:Tnn
|
APN |
1 |
159,953,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
1mM(1):Tnn
|
UTSW |
1 |
159,924,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4305001:Tnn
|
UTSW |
1 |
159,913,647 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0023:Tnn
|
UTSW |
1 |
159,932,498 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0316:Tnn
|
UTSW |
1 |
159,948,137 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0492:Tnn
|
UTSW |
1 |
159,948,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0547:Tnn
|
UTSW |
1 |
159,943,907 (GRCm39) |
intron |
probably benign |
|
|
R1067:Tnn
|
UTSW |
1 |
159,952,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1563:Tnn
|
UTSW |
1 |
159,952,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Tnn
|
UTSW |
1 |
159,924,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1615:Tnn
|
UTSW |
1 |
159,945,978 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1637:Tnn
|
UTSW |
1 |
159,975,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1707:Tnn
|
UTSW |
1 |
159,972,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnn
|
UTSW |
1 |
159,975,154 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1797:Tnn
|
UTSW |
1 |
159,968,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1847:Tnn
|
UTSW |
1 |
159,943,752 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1925:Tnn
|
UTSW |
1 |
159,924,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Tnn
|
UTSW |
1 |
159,968,170 (GRCm39) |
splice site |
probably null |
|
|
R2196:Tnn
|
UTSW |
1 |
159,924,798 (GRCm39) |
nonsense |
probably null |
|
|
R2225:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2286:Tnn
|
UTSW |
1 |
159,938,079 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2850:Tnn
|
UTSW |
1 |
159,966,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3110:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3111:Tnn
|
UTSW |
1 |
159,934,625 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3112:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3729:Tnn
|
UTSW |
1 |
159,973,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4183:Tnn
|
UTSW |
1 |
159,924,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4441:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4588:Tnn
|
UTSW |
1 |
159,972,681 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4647:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4648:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4703:Tnn
|
UTSW |
1 |
159,943,815 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4737:Tnn
|
UTSW |
1 |
159,973,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4802:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4868:Tnn
|
UTSW |
1 |
159,958,443 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4977:Tnn
|
UTSW |
1 |
159,948,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Tnn
|
UTSW |
1 |
159,953,949 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5026:Tnn
|
UTSW |
1 |
159,973,707 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Tnn
|
UTSW |
1 |
159,972,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5049:Tnn
|
UTSW |
1 |
159,968,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5119:Tnn
|
UTSW |
1 |
159,948,122 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5128:Tnn
|
UTSW |
1 |
159,950,464 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5234:Tnn
|
UTSW |
1 |
159,972,569 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5398:Tnn
|
UTSW |
1 |
159,975,092 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Tnn
|
UTSW |
1 |
159,950,272 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5452:Tnn
|
UTSW |
1 |
159,937,831 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5466:Tnn
|
UTSW |
1 |
159,948,106 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6022:Tnn
|
UTSW |
1 |
159,937,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6062:Tnn
|
UTSW |
1 |
159,925,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6086:Tnn
|
UTSW |
1 |
159,913,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6132:Tnn
|
UTSW |
1 |
159,973,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6324:Tnn
|
UTSW |
1 |
159,972,774 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6455:Tnn
|
UTSW |
1 |
159,942,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6563:Tnn
|
UTSW |
1 |
159,915,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6650:Tnn
|
UTSW |
1 |
159,942,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6806:Tnn
|
UTSW |
1 |
159,948,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6810:Tnn
|
UTSW |
1 |
159,932,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7157:Tnn
|
UTSW |
1 |
159,953,947 (GRCm39) |
nonsense |
probably null |
|
|
R7243:Tnn
|
UTSW |
1 |
159,934,687 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7340:Tnn
|
UTSW |
1 |
159,973,592 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7472:Tnn
|
UTSW |
1 |
159,937,917 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7502:Tnn
|
UTSW |
1 |
159,937,929 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7527:Tnn
|
UTSW |
1 |
159,946,074 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7608:Tnn
|
UTSW |
1 |
159,915,984 (GRCm39) |
nonsense |
probably null |
|
|
R7746:Tnn
|
UTSW |
1 |
159,942,255 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8096:Tnn
|
UTSW |
1 |
159,950,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8136:Tnn
|
UTSW |
1 |
159,934,630 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8191:Tnn
|
UTSW |
1 |
159,953,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8337:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8427:Tnn
|
UTSW |
1 |
159,958,256 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8433:Tnn
|
UTSW |
1 |
159,924,790 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8479:Tnn
|
UTSW |
1 |
159,950,397 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8505:Tnn
|
UTSW |
1 |
159,973,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8554:Tnn
|
UTSW |
1 |
159,937,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Tnn
|
UTSW |
1 |
159,943,846 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8850:Tnn
|
UTSW |
1 |
159,937,814 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8928:Tnn
|
UTSW |
1 |
159,953,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Tnn
|
UTSW |
1 |
159,953,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0019:Tnn
|
UTSW |
1 |
159,913,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnn
|
UTSW |
1 |
159,973,863 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Tnn
|
UTSW |
1 |
159,954,097 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCAGGTCGCAATTCTTCTG -3'
(R):5'- GGGTAAGTTCCATTCAGCCAG -3'
Sequencing Primer
(F):5'- CAATTCTTCTGCGGTGTCTGAAGAC -3'
(R):5'- ATTCAGCCAGCCCTCATGG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation