Incidental Mutation 'R4701:Fmn1'
| ID |
355997 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fmn1
|
| Ensembl Gene |
ENSMUSG00000044042 |
| Gene Name |
formin 1 |
| Synonyms |
formin-1, Fmn |
| MMRRC Submission |
041949-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.249)
|
| Stock # |
R4701 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
113158081-113547112 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 113414416 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Phenylalanine
at position 895
(Y895F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000080093
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081349]
[ENSMUST00000099576]
[ENSMUST00000102547]
[ENSMUST00000161731]
|
| AlphaFold |
Q05860 |
| PDB Structure |
FBP28WW2 domain in complex with the PPLIPPPP peptide [SOLUTION NMR]
FBP28WW2 domain in complex with PTPPPLPP peptide [SOLUTION NMR]
FBP28WW2 domain in complex with a PPPLIPPPP peptide [SOLUTION NMR]
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000081349
AA Change: Y895F
PolyPhen 2
Score 0.758 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000080093
Gene: ENSMUSG00000044042
AA Change: Y895F
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:FH2
|
25 |
641 |
N/A |
BLAST |
|
SCOP:d1jvr__
|
668 |
699 |
2e-3 |
SMART |
|
FH2
|
757 |
1162 |
1.16e-137 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000099576
AA Change: Y1121F
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000097171
Gene: ENSMUSG00000044042
AA Change: Y1121F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
173 |
N/A |
INTRINSIC |
|
Blast:FH2
|
352 |
861 |
N/A |
BLAST |
|
SCOP:d1jvr__
|
894 |
925 |
2e-3 |
SMART |
|
FH2
|
983 |
1388 |
1.16e-137 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000102547
AA Change: Y1121F
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000099606
Gene: ENSMUSG00000044042
AA Change: Y1121F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
173 |
N/A |
INTRINSIC |
|
Blast:FH2
|
352 |
861 |
N/A |
BLAST |
|
SCOP:d1jvr__
|
894 |
925 |
2e-3 |
SMART |
|
FH2
|
983 |
1424 |
1.03e-134 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000161731
AA Change: Y1023F
PolyPhen 2
Score 0.507 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000125052
Gene: ENSMUSG00000044042
AA Change: Y1023F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
173 |
N/A |
INTRINSIC |
|
Blast:FH2
|
352 |
619 |
1e-62 |
BLAST |
|
Blast:FH2
|
625 |
765 |
3e-53 |
BLAST |
|
SCOP:d1jvr__
|
796 |
827 |
2e-3 |
SMART |
|
FH2
|
885 |
1290 |
1.16e-137 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185668
AA Change: Y970F
|
| Meta Mutation Damage Score |
0.0972 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
96% (108/112) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
PHENOTYPE: Homozygotes for spontaneous, irradiation-induced, and transgene-insertional mutations show severe syndactyly and oligodactyly of the feet, abnormal long bones (including radius-ulna fusions), and reduced or absent kidneys. Many mutants survive and breed. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aarsd1 |
T |
C |
11: 101,301,986 (GRCm39) |
I196V |
probably benign |
Het |
| Aass |
T |
A |
6: 23,075,855 (GRCm39) |
K761* |
probably null |
Het |
| Abca13 |
A |
G |
11: 9,242,306 (GRCm39) |
T1390A |
possibly damaging |
Het |
| Abhd16a |
T |
C |
17: 35,315,582 (GRCm39) |
|
probably null |
Het |
| Acad11 |
C |
T |
9: 103,972,764 (GRCm39) |
Q486* |
probably null |
Het |
| Actl9 |
T |
C |
17: 33,652,909 (GRCm39) |
L323P |
probably benign |
Het |
| Adam12 |
T |
A |
7: 133,518,191 (GRCm39) |
I650F |
possibly damaging |
Het |
| Adgre4 |
A |
T |
17: 56,091,971 (GRCm39) |
D77V |
probably damaging |
Het |
| Ankrd26 |
A |
G |
6: 118,483,446 (GRCm39) |
F1586S |
possibly damaging |
Het |
| Anpep |
T |
C |
7: 79,489,213 (GRCm39) |
T320A |
probably benign |
Het |
| Arl15 |
T |
A |
13: 114,104,261 (GRCm39) |
C133S |
probably benign |
Het |
| Ascc3 |
A |
G |
10: 50,596,760 (GRCm39) |
N1230S |
possibly damaging |
Het |
| Atf4 |
T |
A |
15: 80,141,618 (GRCm39) |
I336K |
probably damaging |
Het |
| Atp7b |
A |
T |
8: 22,490,137 (GRCm39) |
S1044T |
probably benign |
Het |
| Atp8b4 |
A |
G |
2: 126,256,213 (GRCm39) |
F249L |
probably damaging |
Het |
| AU021092 |
G |
T |
16: 5,030,057 (GRCm39) |
N319K |
probably benign |
Het |
| Bbs4 |
A |
G |
9: 59,230,802 (GRCm39) |
V440A |
probably benign |
Het |
| Bpifb4 |
G |
T |
2: 153,792,305 (GRCm39) |
G450C |
probably damaging |
Het |
| Cadm1 |
G |
A |
9: 47,730,120 (GRCm39) |
|
probably benign |
Het |
| Ccser2 |
G |
A |
14: 36,660,654 (GRCm39) |
L500F |
probably damaging |
Het |
| Cd22 |
T |
A |
7: 30,575,578 (GRCm39) |
I155F |
probably damaging |
Het |
| Cdkl4 |
A |
T |
17: 80,851,081 (GRCm39) |
V207E |
probably damaging |
Het |
| Cfap251 |
A |
G |
5: 123,460,676 (GRCm39) |
K1213E |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,958,067 (GRCm39) |
D947G |
probably damaging |
Het |
| Cntn6 |
T |
C |
6: 104,781,321 (GRCm39) |
V397A |
probably benign |
Het |
| Cpox |
T |
A |
16: 58,498,332 (GRCm39) |
Y388* |
probably null |
Het |
| Dab1 |
C |
T |
4: 104,588,948 (GRCm39) |
A524V |
probably benign |
Het |
| Dda1 |
T |
A |
8: 71,926,454 (GRCm39) |
Y58N |
probably damaging |
Het |
| Dennd4a |
C |
T |
9: 64,804,639 (GRCm39) |
T1326I |
possibly damaging |
Het |
| Eps8l2 |
A |
T |
7: 140,937,173 (GRCm39) |
I338F |
probably damaging |
Het |
| Fbxo42 |
A |
G |
4: 140,927,120 (GRCm39) |
T467A |
probably benign |
Het |
| Flt4 |
T |
C |
11: 49,517,635 (GRCm39) |
F319S |
possibly damaging |
Het |
| Gm6887 |
C |
A |
7: 42,114,517 (GRCm39) |
|
noncoding transcript |
Het |
| Grid2 |
A |
G |
6: 64,642,899 (GRCm39) |
D887G |
probably benign |
Het |
| Grm6 |
C |
T |
11: 50,753,837 (GRCm39) |
P714S |
probably damaging |
Het |
| Gsto2 |
A |
G |
19: 47,873,095 (GRCm39) |
I157V |
probably benign |
Het |
| Il15ra |
A |
G |
2: 11,723,156 (GRCm39) |
|
probably null |
Het |
| Impg1 |
A |
G |
9: 80,221,682 (GRCm39) |
F713L |
probably benign |
Het |
| Jag1 |
T |
A |
2: 136,936,376 (GRCm39) |
T373S |
probably benign |
Het |
| Kcnh3 |
T |
A |
15: 99,139,826 (GRCm39) |
L904Q |
probably benign |
Het |
| Kctd19 |
C |
A |
8: 106,117,061 (GRCm39) |
G356V |
possibly damaging |
Het |
| Kdm5b |
T |
A |
1: 134,533,750 (GRCm39) |
|
probably benign |
Het |
| Kif1a |
T |
C |
1: 93,006,557 (GRCm39) |
I37V |
probably damaging |
Het |
| Lama5 |
G |
A |
2: 179,833,489 (GRCm39) |
R1508C |
probably damaging |
Het |
| Lamb1 |
T |
A |
12: 31,316,847 (GRCm39) |
C65* |
probably null |
Het |
| Lingo1 |
A |
G |
9: 56,527,542 (GRCm39) |
F349S |
probably damaging |
Het |
| Loxl4 |
G |
A |
19: 42,596,052 (GRCm39) |
H147Y |
probably benign |
Het |
| Lrrn4cl |
T |
A |
19: 8,829,419 (GRCm39) |
N132K |
probably damaging |
Het |
| Med17 |
A |
T |
9: 15,181,656 (GRCm39) |
H31Q |
probably damaging |
Het |
| Med23 |
A |
T |
10: 24,769,546 (GRCm39) |
L476F |
probably damaging |
Het |
| Mgst1 |
A |
T |
6: 138,127,836 (GRCm39) |
D66V |
probably damaging |
Het |
| Mroh2a |
T |
C |
1: 88,162,334 (GRCm39) |
|
probably null |
Het |
| Mroh2a |
A |
C |
1: 88,169,340 (GRCm39) |
I672L |
probably benign |
Het |
| Muc4 |
A |
T |
16: 32,576,220 (GRCm39) |
|
probably benign |
Het |
| Myo18a |
C |
T |
11: 77,708,491 (GRCm39) |
T30M |
probably damaging |
Het |
| Ncapg2 |
G |
T |
12: 116,404,238 (GRCm39) |
R903L |
probably benign |
Het |
| Nme1 |
A |
G |
11: 93,856,734 (GRCm39) |
I9T |
probably damaging |
Het |
| Nmt2 |
T |
A |
2: 3,323,678 (GRCm39) |
I357N |
probably benign |
Het |
| Nphp4 |
T |
C |
4: 152,581,116 (GRCm39) |
F100S |
probably damaging |
Het |
| Oca2 |
C |
A |
7: 55,904,750 (GRCm39) |
T72K |
probably benign |
Het |
| Or52e4 |
A |
T |
7: 104,706,086 (GRCm39) |
D211V |
probably damaging |
Het |
| Or52e7 |
A |
T |
7: 104,684,798 (GRCm39) |
D131V |
probably damaging |
Het |
| Or52z15 |
G |
A |
7: 103,332,269 (GRCm39) |
V105M |
probably damaging |
Het |
| Or7h8 |
T |
C |
9: 20,123,921 (GRCm39) |
I92T |
probably damaging |
Het |
| Or9s15 |
C |
A |
1: 92,525,160 (GRCm39) |
D306E |
probably benign |
Het |
| Plce1 |
A |
T |
19: 38,713,451 (GRCm39) |
T1240S |
probably benign |
Het |
| Plch1 |
A |
T |
3: 63,606,917 (GRCm39) |
|
probably null |
Het |
| Plxna4 |
T |
C |
6: 32,493,623 (GRCm39) |
D331G |
probably damaging |
Het |
| Ppp1r3a |
T |
C |
6: 14,718,992 (GRCm39) |
T641A |
probably benign |
Het |
| Rab32 |
A |
G |
10: 10,426,598 (GRCm39) |
L116P |
probably benign |
Het |
| Recql4 |
C |
T |
15: 76,592,785 (GRCm39) |
C302Y |
probably damaging |
Het |
| Rorc |
G |
C |
3: 94,299,017 (GRCm39) |
E391Q |
probably null |
Het |
| Saa4 |
A |
T |
7: 46,381,051 (GRCm39) |
F24I |
possibly damaging |
Het |
| Sall1 |
T |
A |
8: 89,757,788 (GRCm39) |
K772M |
probably damaging |
Het |
| Sdk1 |
T |
G |
5: 142,170,986 (GRCm39) |
L1950V |
probably damaging |
Het |
| Sil1 |
T |
C |
18: 35,399,949 (GRCm39) |
E352G |
probably benign |
Het |
| Slc26a3 |
C |
T |
12: 31,497,773 (GRCm39) |
P59L |
probably damaging |
Het |
| Smco2 |
T |
C |
6: 146,763,440 (GRCm39) |
|
probably benign |
Het |
| Sppl3 |
A |
G |
5: 115,241,372 (GRCm39) |
|
probably null |
Het |
| St6gal2 |
T |
A |
17: 55,803,345 (GRCm39) |
V360D |
probably damaging |
Het |
| Stard9 |
G |
A |
2: 120,536,194 (GRCm39) |
R345Q |
possibly damaging |
Het |
| Susd4 |
T |
A |
1: 182,719,626 (GRCm39) |
Y414N |
probably damaging |
Het |
| Tenm4 |
T |
C |
7: 96,544,556 (GRCm39) |
Y2191H |
probably damaging |
Het |
| Tln2 |
A |
G |
9: 67,253,809 (GRCm39) |
V754A |
probably benign |
Het |
| Tmem132c |
T |
A |
5: 127,641,560 (GRCm39) |
|
probably benign |
Het |
| Tnn |
A |
T |
1: 159,975,338 (GRCm39) |
S30T |
possibly damaging |
Het |
| Trpd52l3 |
G |
T |
19: 29,981,895 (GRCm39) |
V217F |
probably damaging |
Het |
| Trpm1 |
G |
T |
7: 63,893,248 (GRCm39) |
L1033F |
probably damaging |
Het |
| Tulp2 |
A |
G |
7: 45,167,348 (GRCm39) |
E182G |
probably damaging |
Het |
| Ubr4 |
A |
G |
4: 139,198,647 (GRCm39) |
K4490R |
possibly damaging |
Het |
| Usp17la |
A |
T |
7: 104,509,856 (GRCm39) |
R154* |
probably null |
Het |
| Vmn2r17 |
T |
G |
5: 109,575,849 (GRCm39) |
M240R |
probably damaging |
Het |
| Vmn2r22 |
T |
A |
6: 123,627,428 (GRCm39) |
N56I |
probably benign |
Het |
| Zdhhc21 |
A |
T |
4: 82,738,571 (GRCm39) |
I206N |
possibly damaging |
Het |
| Zfp148 |
T |
A |
16: 33,277,278 (GRCm39) |
D122E |
probably benign |
Het |
| Zfp804a |
A |
T |
2: 82,086,926 (GRCm39) |
S252C |
probably damaging |
Het |
| Zgrf1 |
C |
T |
3: 127,392,353 (GRCm39) |
T1291I |
probably benign |
Het |
|
| Other mutations in Fmn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00495:Fmn1
|
APN |
2 |
113,274,812 (GRCm39) |
intron |
probably benign |
|
|
IGL01520:Fmn1
|
APN |
2 |
113,274,713 (GRCm39) |
intron |
probably benign |
|
|
IGL02039:Fmn1
|
APN |
2 |
113,195,425 (GRCm39) |
missense |
unknown |
|
|
IGL02222:Fmn1
|
APN |
2 |
113,423,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02238:Fmn1
|
APN |
2 |
113,412,470 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02373:Fmn1
|
APN |
2 |
113,194,471 (GRCm39) |
missense |
unknown |
|
|
IGL02490:Fmn1
|
APN |
2 |
113,359,817 (GRCm39) |
splice site |
probably benign |
|
|
IGL02506:Fmn1
|
APN |
2 |
113,355,640 (GRCm39) |
missense |
unknown |
|
|
IGL02684:Fmn1
|
APN |
2 |
113,355,622 (GRCm39) |
missense |
unknown |
|
|
IGL03008:Fmn1
|
APN |
2 |
113,195,445 (GRCm39) |
missense |
unknown |
|
|
IGL03058:Fmn1
|
APN |
2 |
113,272,159 (GRCm39) |
intron |
probably benign |
|
|
IGL03076:Fmn1
|
APN |
2 |
113,414,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
FR4304:Fmn1
|
UTSW |
2 |
113,356,128 (GRCm39) |
small insertion |
probably benign |
|
|
FR4304:Fmn1
|
UTSW |
2 |
113,356,119 (GRCm39) |
small insertion |
probably benign |
|
|
FR4342:Fmn1
|
UTSW |
2 |
113,356,128 (GRCm39) |
small insertion |
probably benign |
|
|
FR4589:Fmn1
|
UTSW |
2 |
113,356,119 (GRCm39) |
small insertion |
probably benign |
|
|
FR4589:Fmn1
|
UTSW |
2 |
113,356,118 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Fmn1
|
UTSW |
2 |
113,356,129 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Fmn1
|
UTSW |
2 |
113,356,126 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Fmn1
|
UTSW |
2 |
113,356,123 (GRCm39) |
small insertion |
probably benign |
|
|
R0349:Fmn1
|
UTSW |
2 |
113,196,141 (GRCm39) |
missense |
unknown |
|
|
R0452:Fmn1
|
UTSW |
2 |
113,467,124 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0529:Fmn1
|
UTSW |
2 |
113,538,198 (GRCm39) |
splice site |
probably benign |
|
|
R1215:Fmn1
|
UTSW |
2 |
113,523,375 (GRCm39) |
nonsense |
probably null |
|
|
R1471:Fmn1
|
UTSW |
2 |
113,523,439 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1489:Fmn1
|
UTSW |
2 |
113,195,557 (GRCm39) |
missense |
unknown |
|
|
R1491:Fmn1
|
UTSW |
2 |
113,426,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1551:Fmn1
|
UTSW |
2 |
113,356,207 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1558:Fmn1
|
UTSW |
2 |
113,523,463 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1588:Fmn1
|
UTSW |
2 |
113,196,043 (GRCm39) |
missense |
unknown |
|
|
R1602:Fmn1
|
UTSW |
2 |
113,355,968 (GRCm39) |
missense |
unknown |
|
|
R1690:Fmn1
|
UTSW |
2 |
113,355,827 (GRCm39) |
missense |
unknown |
|
|
R1772:Fmn1
|
UTSW |
2 |
113,195,700 (GRCm39) |
missense |
unknown |
|
|
R1867:Fmn1
|
UTSW |
2 |
113,539,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1923:Fmn1
|
UTSW |
2 |
113,260,066 (GRCm39) |
intron |
probably benign |
|
|
R1941:Fmn1
|
UTSW |
2 |
113,195,488 (GRCm39) |
missense |
unknown |
|
|
R2019:Fmn1
|
UTSW |
2 |
113,194,825 (GRCm39) |
missense |
unknown |
|
|
R2140:Fmn1
|
UTSW |
2 |
113,425,393 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2164:Fmn1
|
UTSW |
2 |
113,195,962 (GRCm39) |
missense |
unknown |
|
|
R2395:Fmn1
|
UTSW |
2 |
113,195,526 (GRCm39) |
missense |
unknown |
|
|
R2999:Fmn1
|
UTSW |
2 |
113,195,439 (GRCm39) |
missense |
unknown |
|
|
R3405:Fmn1
|
UTSW |
2 |
113,194,693 (GRCm39) |
missense |
unknown |
|
|
R3407:Fmn1
|
UTSW |
2 |
113,195,400 (GRCm39) |
missense |
unknown |
|
|
R3771:Fmn1
|
UTSW |
2 |
113,412,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3772:Fmn1
|
UTSW |
2 |
113,412,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3773:Fmn1
|
UTSW |
2 |
113,412,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3777:Fmn1
|
UTSW |
2 |
113,195,467 (GRCm39) |
missense |
unknown |
|
|
R4166:Fmn1
|
UTSW |
2 |
113,467,080 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4477:Fmn1
|
UTSW |
2 |
113,274,744 (GRCm39) |
intron |
probably benign |
|
|
R4614:Fmn1
|
UTSW |
2 |
113,195,494 (GRCm39) |
missense |
unknown |
|
|
R4867:Fmn1
|
UTSW |
2 |
113,414,465 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5063:Fmn1
|
UTSW |
2 |
113,195,266 (GRCm39) |
missense |
unknown |
|
|
R5224:Fmn1
|
UTSW |
2 |
113,195,470 (GRCm39) |
missense |
unknown |
|
|
R5510:Fmn1
|
UTSW |
2 |
113,426,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6083:Fmn1
|
UTSW |
2 |
113,194,648 (GRCm39) |
missense |
unknown |
|
|
R6234:Fmn1
|
UTSW |
2 |
113,196,000 (GRCm39) |
missense |
unknown |
|
|
R6266:Fmn1
|
UTSW |
2 |
113,426,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6764:Fmn1
|
UTSW |
2 |
113,355,560 (GRCm39) |
missense |
unknown |
|
|
R7054:Fmn1
|
UTSW |
2 |
113,195,353 (GRCm39) |
missense |
unknown |
|
|
R7311:Fmn1
|
UTSW |
2 |
113,356,025 (GRCm39) |
missense |
unknown |
|
|
R7439:Fmn1
|
UTSW |
2 |
113,271,956 (GRCm39) |
missense |
unknown |
|
|
R7440:Fmn1
|
UTSW |
2 |
113,271,956 (GRCm39) |
missense |
unknown |
|
|
R7441:Fmn1
|
UTSW |
2 |
113,271,956 (GRCm39) |
missense |
unknown |
|
|
R7444:Fmn1
|
UTSW |
2 |
113,271,956 (GRCm39) |
missense |
unknown |
|
|
R7461:Fmn1
|
UTSW |
2 |
113,194,416 (GRCm39) |
missense |
unknown |
|
|
R7526:Fmn1
|
UTSW |
2 |
113,518,479 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7540:Fmn1
|
UTSW |
2 |
113,359,655 (GRCm39) |
splice site |
probably null |
|
|
R7576:Fmn1
|
UTSW |
2 |
113,195,353 (GRCm39) |
missense |
unknown |
|
|
R7657:Fmn1
|
UTSW |
2 |
113,355,538 (GRCm39) |
missense |
unknown |
|
|
R7669:Fmn1
|
UTSW |
2 |
113,195,822 (GRCm39) |
missense |
unknown |
|
|
R7713:Fmn1
|
UTSW |
2 |
113,356,159 (GRCm39) |
missense |
unknown |
|
|
R7841:Fmn1
|
UTSW |
2 |
113,359,810 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7953:Fmn1
|
UTSW |
2 |
113,426,689 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7959:Fmn1
|
UTSW |
2 |
113,195,967 (GRCm39) |
missense |
unknown |
|
|
R8041:Fmn1
|
UTSW |
2 |
113,194,939 (GRCm39) |
missense |
unknown |
|
|
R8152:Fmn1
|
UTSW |
2 |
113,196,037 (GRCm39) |
missense |
unknown |
|
|
R8203:Fmn1
|
UTSW |
2 |
113,355,620 (GRCm39) |
missense |
unknown |
|
|
R8318:Fmn1
|
UTSW |
2 |
113,195,502 (GRCm39) |
missense |
unknown |
|
|
R8356:Fmn1
|
UTSW |
2 |
113,195,385 (GRCm39) |
missense |
unknown |
|
|
R8456:Fmn1
|
UTSW |
2 |
113,195,385 (GRCm39) |
missense |
unknown |
|
|
R8698:Fmn1
|
UTSW |
2 |
113,260,152 (GRCm39) |
missense |
unknown |
|
|
R8861:Fmn1
|
UTSW |
2 |
113,195,149 (GRCm39) |
missense |
unknown |
|
|
R8907:Fmn1
|
UTSW |
2 |
113,355,914 (GRCm39) |
missense |
unknown |
|
|
R9147:Fmn1
|
UTSW |
2 |
113,271,973 (GRCm39) |
missense |
unknown |
|
|
R9148:Fmn1
|
UTSW |
2 |
113,271,973 (GRCm39) |
missense |
unknown |
|
|
R9536:Fmn1
|
UTSW |
2 |
113,309,262 (GRCm39) |
missense |
unknown |
|
|
R9574:Fmn1
|
UTSW |
2 |
113,425,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9577:Fmn1
|
UTSW |
2 |
113,194,470 (GRCm39) |
missense |
unknown |
|
|
RF003:Fmn1
|
UTSW |
2 |
113,356,131 (GRCm39) |
small insertion |
probably benign |
|
|
Z1088:Fmn1
|
UTSW |
2 |
113,272,270 (GRCm39) |
intron |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACCATTTGCTTTAGCTGGTAAATGC -3'
(R):5'- ACGCTGTTGTAACTCAGCC -3'
Sequencing Primer
(F):5'- GCTTTAGCTGGTAAATGCCAAGC -3'
(R):5'- GTTGTAACTCAGCCCTCTACG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation