Mutagenetix > Incidental Mutation

Incidental Mutation 'R4735:Bltp1'

356432

Institutional Source

Beutler Lab

Gene Symbol

Bltp1

Ensembl Gene

ENSMUSG00000037270

Gene Name

bridge-like lipid transfer protein family member 1

Synonyms

FSA, 4932438A13Rik, Tweek

MMRRC Submission

041962-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R4735 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

36917253-37107182 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 37059116 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 3267 (N3267K)

Ref Sequence

ENSEMBL: ENSMUSP00000117808 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057272] [ENSMUST00000152564]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000057272
AA Change: N3267K

PolyPhen 2 Score 0.841 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000060199
Gene: ENSMUSG00000037270
AA Change: N3267K

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000146948

SMART Domains

Protein: ENSMUSP00000121356
Gene: ENSMUSG00000037270

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	167	177	N/A	INTRINSIC
low complexity region	458	483	N/A	INTRINSIC
low complexity region	557	578	N/A	INTRINSIC
low complexity region	730	744	N/A	INTRINSIC
low complexity region	747	755	N/A	INTRINSIC
low complexity region	823	855	N/A	INTRINSIC
low complexity region	878	891	N/A	INTRINSIC
low complexity region	1065	1086	N/A	INTRINSIC
FSA_C	1092	1696	N/A	SMART
low complexity region	1699	1710	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000152564
AA Change: N3267K

PolyPhen 2 Score 0.841 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000117808
Gene: ENSMUSG00000037270
AA Change: N3267K

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.1%
20x: 95.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Allele List at MGI

Other mutations in this stock

Total: 133 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2700049A03Rik	T	A	12: 71,262,897 (GRCm39)	I1410N	possibly damaging	Het
9230106D20Rik	T	C	10: 19,536,001 (GRCm39)		noncoding transcript	Het
Acsf3	T	A	8: 123,508,218 (GRCm39)	I238N	probably damaging	Het
Ahctf1	T	C	1: 179,580,964 (GRCm39)	N1746S	probably benign	Het
Akap3	T	C	6: 126,842,601 (GRCm39)	S407P	probably damaging	Het
Ankfy1	T	A	11: 72,621,437 (GRCm39)	M241K	probably benign	Het
Ano7	C	A	1: 93,328,216 (GRCm39)	T622K	probably benign	Het
App	T	C	16: 84,900,202 (GRCm39)	T83A	probably damaging	Het
Arhgef28	T	A	13: 98,036,237 (GRCm39)	E1674V	probably damaging	Het
Asb2	C	A	12: 103,291,317 (GRCm39)	V489L	probably benign	Het
Atrn	T	C	2: 130,862,910 (GRCm39)	V1330A	probably benign	Het
Brca1	A	G	11: 101,383,001 (GRCm39)		probably null	Het
Bspry	G	A	4: 62,404,762 (GRCm39)	R186Q	probably damaging	Het
Ccdc168	A	G	1: 44,100,861 (GRCm39)	I79T	probably benign	Het
Cdkn2d	C	G	9: 21,202,185 (GRCm39)	V21L	probably benign	Het
Celsr1	T	A	15: 85,790,230 (GRCm39)		probably null	Het
Ckap4	A	G	10: 84,369,384 (GRCm39)	V116A	possibly damaging	Het
Crb3	A	G	17: 57,372,207 (GRCm39)	T85A	probably damaging	Het
Cyld	T	C	8: 89,456,278 (GRCm39)	S443P	probably damaging	Het
Cyp27a1	T	G	1: 74,776,366 (GRCm39)	V434G	possibly damaging	Het
Cyp2b13	A	G	7: 25,787,720 (GRCm39)	T339A	probably benign	Het
Dars1	A	T	1: 128,303,971 (GRCm39)	L252*	probably null	Het
Dcaf10	G	A	4: 45,372,769 (GRCm39)	R394Q	possibly damaging	Het
Ddx55	T	C	5: 124,704,539 (GRCm39)	F382S	probably damaging	Het
Dmtf1l	T	A	X: 125,722,217 (GRCm39)	K296M	probably damaging	Het
Dnah7b	G	A	1: 46,106,115 (GRCm39)	R33Q	unknown	Het
Dnm2	G	T	9: 21,385,883 (GRCm39)	S302I	probably damaging	Het
Dock4	T	A	12: 40,681,525 (GRCm39)	F75I	probably benign	Het
Dpp10	T	C	1: 123,326,356 (GRCm39)	N365S	probably benign	Het
Dpy19l3	G	T	7: 35,422,146 (GRCm39)	Q236K	probably benign	Het
Dsp	T	C	13: 38,380,016 (GRCm39)	S1655P	probably damaging	Het
Ebpl	A	T	14: 61,579,567 (GRCm39)	I117N	probably damaging	Het
Edc4	T	A	8: 106,613,818 (GRCm39)	V386E	probably damaging	Het
Eif2s2	T	A	2: 154,720,467 (GRCm39)		probably null	Het
Elob	A	T	17: 24,046,562 (GRCm39)		probably null	Het
Enox2	T	C	X: 48,158,554 (GRCm39)	I71V	probably damaging	Het
Fez1	A	T	9: 36,772,141 (GRCm39)	K149*	probably null	Het
Fhip2a	A	G	19: 57,359,661 (GRCm39)	E67G	probably damaging	Het
Fign	A	G	2: 63,810,782 (GRCm39)	Y163H	probably damaging	Het
Flnc	G	A	6: 29,455,812 (GRCm39)	G2048S	probably damaging	Het
Fras1	A	G	5: 96,736,022 (GRCm39)	D539G	probably benign	Het
Frmd4b	T	C	6: 97,436,220 (GRCm39)		probably benign	Het
Gan	C	T	8: 117,920,970 (GRCm39)	T402M	probably damaging	Het
Ganc	T	A	2: 120,267,104 (GRCm39)		silent	Het
Ggt6	C	A	11: 72,327,425 (GRCm39)	R103S	probably benign	Het
Gli2	T	C	1: 118,768,052 (GRCm39)	D725G	probably damaging	Het
Gm15446	T	A	5: 110,090,818 (GRCm39)	C357S	probably damaging	Het
Gm44501	A	G	17: 40,889,810 (GRCm39)	N108S	probably benign	Het
Gm6309	A	T	5: 146,105,054 (GRCm39)	D286E	probably damaging	Het
Gm6358	G	A	16: 88,937,848 (GRCm39)	G29E	unknown	Het
Grik5	A	G	7: 24,757,713 (GRCm39)	I422T	probably damaging	Het
Grin2c	A	G	11: 115,140,422 (GRCm39)	I1232T	possibly damaging	Het
Gsg1	C	T	6: 135,214,405 (GRCm39)	R365H	possibly damaging	Het
H2-M2	A	G	17: 37,794,135 (GRCm39)	S30P	possibly damaging	Het
Hcfc2	A	G	10: 82,547,914 (GRCm39)	D302G	probably damaging	Het
Hk2	T	C	6: 82,721,955 (GRCm39)	D128G	probably benign	Het
Hmcn2	C	A	2: 31,273,787 (GRCm39)	Q1380K	probably benign	Het
Hsp90b1	G	T	10: 86,529,819 (GRCm39)	P617T	probably damaging	Het
Htr1d	A	G	4: 136,170,197 (GRCm39)	E142G	probably benign	Het
Hydin	G	A	8: 111,282,264 (GRCm39)		probably null	Het
Il1r1	T	A	1: 40,332,455 (GRCm39)	N81K	probably benign	Het
Inpp5b	T	C	4: 124,677,760 (GRCm39)	S407P	probably damaging	Het
Itpkb	T	C	1: 180,245,780 (GRCm39)	Y766H	probably damaging	Het
Lyrm2	T	A	4: 32,801,150 (GRCm39)	I65N	probably damaging	Het
Mink1	T	A	11: 70,500,086 (GRCm39)		probably null	Het
Mkrn3	C	T	7: 62,069,452 (GRCm39)	R113H	probably damaging	Het
Msx3	G	A	7: 139,627,798 (GRCm39)	A157V	probably damaging	Het
Nrxn2	T	G	19: 6,548,484 (GRCm39)	V59G	possibly damaging	Het
Nt5c3b	T	C	11: 100,331,732 (GRCm39)	T12A	probably benign	Het
Nwd2	G	A	5: 63,965,594 (GRCm39)	R1726Q	probably benign	Het
Nynrin	A	G	14: 56,107,625 (GRCm39)	T911A	probably benign	Het
Or11i1	T	A	3: 106,728,996 (GRCm39)	Y293F	probably damaging	Het
Or4p18	T	C	2: 88,233,267 (GRCm39)	T4A	probably benign	Het
Or51aa5	A	G	7: 103,167,030 (GRCm39)	I187T	possibly damaging	Het
Or51af1	C	T	7: 103,141,267 (GRCm39)	V273M	possibly damaging	Het
Or52n20	C	T	7: 104,320,200 (GRCm39)	T97I	probably benign	Het
Or5p66	A	G	7: 107,885,520 (GRCm39)	M271T	probably benign	Het
Or6c212	A	G	10: 129,558,792 (GRCm39)	I207T	probably benign	Het
Patl1	G	T	19: 11,899,869 (GRCm39)	M220I	probably benign	Het
Pcnx2	A	T	8: 126,554,780 (GRCm39)		probably null	Het
Pigr	A	T	1: 130,774,291 (GRCm39)	T424S	probably damaging	Het
Pik3c2b	T	A	1: 132,994,787 (GRCm39)	D250E	probably benign	Het
Ppa2	G	A	3: 133,076,186 (GRCm39)	E272K	probably benign	Het
Pramel7	G	A	2: 87,321,187 (GRCm39)	Q283*	probably null	Het
Prelid3b	A	G	2: 174,307,683 (GRCm39)	I81T	probably benign	Het
Prpf38a	T	C	4: 108,436,242 (GRCm39)	I24V	possibly damaging	Het
Ptger2	A	G	14: 45,239,295 (GRCm39)	D311G	possibly damaging	Het
Rab4b	A	T	7: 26,872,191 (GRCm39)		probably benign	Het
Rad17	A	C	13: 100,755,637 (GRCm39)	D581E	probably damaging	Het
Samd11	T	C	4: 156,333,230 (GRCm39)	T333A	probably benign	Het
Scaf4	C	T	16: 90,049,320 (GRCm39)	D256N	unknown	Het
Serinc2	A	G	4: 130,157,438 (GRCm39)	F82L	probably benign	Het
Serpina3g	T	A	12: 104,205,372 (GRCm39)	V37E	probably damaging	Het
Serpinb9c	T	A	13: 33,334,254 (GRCm39)	M263L	probably benign	Het
Shbg	A	G	11: 69,508,326 (GRCm39)	I67T	possibly damaging	Het
Slc25a48	G	A	13: 56,596,887 (GRCm39)		probably null	Het
Slc25a54	T	C	3: 109,005,923 (GRCm39)	W144R	probably damaging	Het
Slc34a1	A	T	13: 55,561,397 (GRCm39)	T621S	probably benign	Het
Slc6a18	A	T	13: 73,814,554 (GRCm39)	C419S	probably benign	Het
Smc5	A	T	19: 23,220,069 (GRCm39)	D389E	probably benign	Het
Smco3	T	A	6: 136,808,636 (GRCm39)	E79D	probably damaging	Het
Sox5	A	G	6: 143,906,561 (GRCm39)	F298S	probably damaging	Het
Sphkap	A	G	1: 83,256,838 (GRCm39)	S304P	probably benign	Het
Tcea2	C	T	2: 181,328,514 (GRCm39)	T211I	probably damaging	Het
Tcf4	G	T	18: 69,697,226 (GRCm39)	S34I	possibly damaging	Het
Tlr4	C	T	4: 66,759,435 (GRCm39)	R743C	probably damaging	Het
Tmem183a	T	C	1: 134,288,620 (GRCm39)	E67G	probably damaging	Het
Tpr	C	T	1: 150,317,947 (GRCm39)	R2152C	possibly damaging	Het
Trbv15	T	C	6: 41,118,358 (GRCm39)	I38T	probably benign	Het
Treh	G	A	9: 44,592,849 (GRCm39)	A125T	probably damaging	Het
Trio	A	T	15: 27,752,875 (GRCm39)		probably null	Het
Ttn	A	G	2: 76,782,293 (GRCm39)	V981A	probably damaging	Het
Uap1l1	A	G	2: 25,252,732 (GRCm39)	L436P	probably damaging	Het
Uba7	A	T	9: 107,854,115 (GRCm39)	I182F	possibly damaging	Het
Unc13c	A	T	9: 73,600,620 (GRCm39)	S1375T	probably benign	Het
Usp48	C	CT	4: 137,360,680 (GRCm39)		probably null	Het
Utp20	A	C	10: 88,652,780 (GRCm39)	V378G	possibly damaging	Het
Vmn1r69	A	T	7: 10,314,926 (GRCm39)		probably benign	Het
Vmn1r86	A	T	7: 12,836,221 (GRCm39)	H218Q	probably damaging	Het
Vmn2r121	T	A	X: 123,038,335 (GRCm39)	I562L	probably benign	Het
Vmn2r45	A	T	7: 8,486,472 (GRCm39)	I272N	probably damaging	Het
Wdr90	A	G	17: 26,078,424 (GRCm39)	V320A	probably benign	Het
Wfikkn1	A	G	17: 26,097,367 (GRCm39)	V319A	possibly damaging	Het
Whamm	A	G	7: 81,221,122 (GRCm39)	D18G	probably benign	Het
Wrn	T	A	8: 33,775,250 (GRCm39)	I605F	probably damaging	Het
Zdhhc18	A	G	4: 133,341,178 (GRCm39)	F232L	probably damaging	Het
Zfp41	T	C	15: 75,490,609 (GRCm39)	I187T	probably benign	Het
Zfp418	A	G	7: 7,185,561 (GRCm39)	Y508C	probably damaging	Het
Zfp560	T	G	9: 20,260,347 (GRCm39)	I172L	probably benign	Het
Zfp943	A	T	17: 22,211,391 (GRCm39)	D159V	probably benign	Het
Zfp955a	T	C	17: 33,460,696 (GRCm39)	I479V	probably benign	Het
Zfpm1	T	A	8: 123,062,219 (GRCm39)	V426D	probably benign	Het
Zic1	C	T	9: 91,246,558 (GRCm39)	M171I	possibly damaging	Het

Other mutations in Bltp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00428:Bltp1	APN	3	37,065,876 (GRCm39)	missense	probably benign	0.00
IGL00434:Bltp1	APN	3	37,041,448 (GRCm39)	missense	probably damaging	0.98
IGL00640:Bltp1	APN	3	36,962,367 (GRCm39)	missense	probably damaging	1.00
IGL00693:Bltp1	APN	3	37,106,696 (GRCm39)	utr 3 prime	probably benign
IGL00721:Bltp1	APN	3	37,084,900 (GRCm39)	splice site	probably null
IGL00756:Bltp1	APN	3	36,962,367 (GRCm39)	missense	probably damaging	1.00
IGL00896:Bltp1	APN	3	37,093,611 (GRCm39)	missense	probably benign
IGL00902:Bltp1	APN	3	37,095,494 (GRCm39)	missense	probably damaging	1.00
IGL00980:Bltp1	APN	3	37,054,190 (GRCm39)	missense	probably damaging	1.00
IGL01019:Bltp1	APN	3	37,061,133 (GRCm39)	critical splice acceptor site	probably null
IGL01025:Bltp1	APN	3	37,100,429 (GRCm39)	missense	possibly damaging	0.89
IGL01306:Bltp1	APN	3	37,059,162 (GRCm39)	splice site	probably benign
IGL01370:Bltp1	APN	3	37,001,904 (GRCm39)	missense	probably benign	0.07
IGL01377:Bltp1	APN	3	37,027,601 (GRCm39)	critical splice donor site	probably null
IGL01401:Bltp1	APN	3	36,996,441 (GRCm39)	missense	probably benign
IGL01419:Bltp1	APN	3	37,102,270 (GRCm39)	missense	probably damaging	1.00
IGL01432:Bltp1	APN	3	37,057,908 (GRCm39)	missense	possibly damaging	0.87
IGL01433:Bltp1	APN	3	36,941,919 (GRCm39)	missense	probably damaging	1.00
IGL01452:Bltp1	APN	3	37,050,457 (GRCm39)	unclassified	probably benign
IGL01520:Bltp1	APN	3	37,027,409 (GRCm39)	nonsense	probably null
IGL01524:Bltp1	APN	3	36,996,531 (GRCm39)	missense	possibly damaging	0.90
IGL01628:Bltp1	APN	3	37,062,634 (GRCm39)	missense	probably damaging	1.00
IGL01638:Bltp1	APN	3	37,028,460 (GRCm39)	missense	probably damaging	1.00
IGL01650:Bltp1	APN	3	37,046,822 (GRCm39)	splice site	probably benign
IGL01717:Bltp1	APN	3	37,088,885 (GRCm39)	missense	probably benign
IGL01767:Bltp1	APN	3	37,095,512 (GRCm39)	missense	probably benign	0.29
IGL01813:Bltp1	APN	3	36,982,669 (GRCm39)	missense	possibly damaging	0.90
IGL01998:Bltp1	APN	3	37,011,165 (GRCm39)	missense	possibly damaging	0.49
IGL02172:Bltp1	APN	3	37,059,022 (GRCm39)	missense	probably damaging	0.99
IGL02197:Bltp1	APN	3	36,960,884 (GRCm39)	missense	probably damaging	1.00
IGL02248:Bltp1	APN	3	37,023,439 (GRCm39)	critical splice donor site	probably null
IGL02273:Bltp1	APN	3	36,975,586 (GRCm39)	splice site	probably benign
IGL02403:Bltp1	APN	3	37,084,813 (GRCm39)	missense	probably benign
IGL02492:Bltp1	APN	3	37,102,262 (GRCm39)	missense	probably benign	0.04
IGL02517:Bltp1	APN	3	37,013,017 (GRCm39)	missense	probably damaging	1.00
IGL02519:Bltp1	APN	3	36,949,464 (GRCm39)	missense	probably damaging	1.00
IGL02586:Bltp1	APN	3	37,098,757 (GRCm39)	nonsense	probably null
IGL02620:Bltp1	APN	3	37,090,094 (GRCm39)	missense	possibly damaging	0.95
IGL02621:Bltp1	APN	3	37,095,633 (GRCm39)	splice site	probably benign
IGL02670:Bltp1	APN	3	37,021,454 (GRCm39)	nonsense	probably null
IGL02806:Bltp1	APN	3	37,000,643 (GRCm39)	missense	possibly damaging	0.95
IGL02985:Bltp1	APN	3	37,012,906 (GRCm39)	missense	probably damaging	0.99
IGL03004:Bltp1	APN	3	37,019,826 (GRCm39)	splice site	probably benign
IGL03037:Bltp1	APN	3	37,023,356 (GRCm39)	missense	probably benign	0.23
IGL03037:Bltp1	APN	3	37,023,357 (GRCm39)	missense	probably damaging	1.00
IGL03062:Bltp1	APN	3	37,092,666 (GRCm39)	splice site	probably benign
IGL03137:Bltp1	APN	3	37,088,751 (GRCm39)	missense	probably damaging	0.98
IGL03150:Bltp1	APN	3	37,002,215 (GRCm39)	missense	probably damaging	1.00
IGL03204:Bltp1	APN	3	37,105,083 (GRCm39)	splice site	probably benign
IGL03207:Bltp1	APN	3	37,004,145 (GRCm39)	missense	possibly damaging	0.73
IGL03256:Bltp1	APN	3	36,960,832 (GRCm39)	splice site	probably benign
IGL03264:Bltp1	APN	3	37,056,784 (GRCm39)	missense	probably damaging	1.00
IGL03265:Bltp1	APN	3	37,102,140 (GRCm39)	missense	probably benign	0.00
IGL03303:Bltp1	APN	3	36,924,226 (GRCm39)	missense	possibly damaging	0.90
admonished	UTSW	3	37,002,453 (GRCm39)	missense	probably damaging	1.00
alerted	UTSW	3	37,087,414 (GRCm39)	missense	possibly damaging	0.85
informed	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
resolved	UTSW	3	36,975,370 (GRCm39)	missense	possibly damaging	0.60
tipped	UTSW	3	37,042,234 (GRCm39)	missense	possibly damaging	0.81
warned	UTSW	3	37,019,770 (GRCm39)	missense	probably damaging	1.00
FR4340:Bltp1	UTSW	3	37,104,901 (GRCm39)	critical splice acceptor site	probably benign
FR4737:Bltp1	UTSW	3	37,104,903 (GRCm39)	critical splice acceptor site	probably benign
PIT4515001:Bltp1	UTSW	3	37,028,385 (GRCm39)	missense	probably damaging	1.00
R0035:Bltp1	UTSW	3	37,041,747 (GRCm39)	nonsense	probably null
R0047:Bltp1	UTSW	3	36,962,341 (GRCm39)	missense	possibly damaging	0.83
R0047:Bltp1	UTSW	3	36,962,341 (GRCm39)	missense	possibly damaging	0.83
R0068:Bltp1	UTSW	3	37,006,370 (GRCm39)	missense	probably benign	0.28
R0068:Bltp1	UTSW	3	37,006,370 (GRCm39)	missense	probably benign	0.28
R0092:Bltp1	UTSW	3	37,082,308 (GRCm39)	missense	probably benign	0.41
R0233:Bltp1	UTSW	3	37,002,712 (GRCm39)	nonsense	probably null
R0233:Bltp1	UTSW	3	37,002,712 (GRCm39)	nonsense	probably null
R0256:Bltp1	UTSW	3	36,971,922 (GRCm39)	missense	probably benign	0.01
R0277:Bltp1	UTSW	3	36,997,331 (GRCm39)	nonsense	probably null
R0321:Bltp1	UTSW	3	36,960,937 (GRCm39)	splice site	probably null
R0323:Bltp1	UTSW	3	36,997,331 (GRCm39)	nonsense	probably null
R0335:Bltp1	UTSW	3	37,023,301 (GRCm39)	missense	probably damaging	1.00
R0375:Bltp1	UTSW	3	37,100,401 (GRCm39)	missense	probably damaging	0.99
R0437:Bltp1	UTSW	3	37,043,953 (GRCm39)	missense	possibly damaging	0.81
R0445:Bltp1	UTSW	3	37,054,214 (GRCm39)	missense	probably damaging	0.99
R0496:Bltp1	UTSW	3	37,041,784 (GRCm39)	missense	probably damaging	1.00
R0531:Bltp1	UTSW	3	37,090,974 (GRCm39)	missense	probably damaging	1.00
R0543:Bltp1	UTSW	3	37,050,607 (GRCm39)	missense	probably benign	0.22
R0545:Bltp1	UTSW	3	37,041,839 (GRCm39)	splice site	probably benign
R0674:Bltp1	UTSW	3	37,098,775 (GRCm39)	missense	possibly damaging	0.86
R0745:Bltp1	UTSW	3	36,982,612 (GRCm39)	missense	probably damaging	1.00
R0755:Bltp1	UTSW	3	37,000,513 (GRCm39)	missense	probably damaging	1.00
R0785:Bltp1	UTSW	3	37,013,483 (GRCm39)	splice site	probably benign
R1056:Bltp1	UTSW	3	37,098,829 (GRCm39)	missense	probably benign	0.44
R1056:Bltp1	UTSW	3	37,037,602 (GRCm39)	missense	possibly damaging	0.69
R1080:Bltp1	UTSW	3	37,042,404 (GRCm39)	missense	probably damaging	1.00
R1103:Bltp1	UTSW	3	37,050,672 (GRCm39)	missense	probably benign
R1119:Bltp1	UTSW	3	37,041,194 (GRCm39)	missense	probably damaging	1.00
R1170:Bltp1	UTSW	3	37,098,780 (GRCm39)	missense	probably damaging	0.98
R1183:Bltp1	UTSW	3	36,949,452 (GRCm39)	missense	possibly damaging	0.51
R1186:Bltp1	UTSW	3	37,050,461 (GRCm39)	unclassified	probably benign
R1201:Bltp1	UTSW	3	37,002,524 (GRCm39)	missense	probably benign
R1219:Bltp1	UTSW	3	37,000,619 (GRCm39)	nonsense	probably null
R1270:Bltp1	UTSW	3	37,006,333 (GRCm39)	missense	probably damaging	1.00
R1273:Bltp1	UTSW	3	37,041,359 (GRCm39)	missense	probably damaging	1.00
R1338:Bltp1	UTSW	3	37,106,684 (GRCm39)	missense	unknown
R1364:Bltp1	UTSW	3	37,041,179 (GRCm39)	missense	probably damaging	1.00
R1437:Bltp1	UTSW	3	36,996,578 (GRCm39)	missense	possibly damaging	0.65
R1447:Bltp1	UTSW	3	37,019,735 (GRCm39)	missense	probably damaging	0.98
R1467:Bltp1	UTSW	3	37,090,094 (GRCm39)	missense	probably damaging	0.99
R1467:Bltp1	UTSW	3	37,090,094 (GRCm39)	missense	probably damaging	0.99
R1470:Bltp1	UTSW	3	37,052,480 (GRCm39)	missense	probably benign	0.31
R1470:Bltp1	UTSW	3	37,052,480 (GRCm39)	missense	probably benign	0.31
R1481:Bltp1	UTSW	3	37,062,583 (GRCm39)	missense	probably damaging	0.99
R1528:Bltp1	UTSW	3	37,106,684 (GRCm39)	missense	unknown
R1533:Bltp1	UTSW	3	37,095,524 (GRCm39)	missense	probably damaging	1.00
R1546:Bltp1	UTSW	3	36,924,205 (GRCm39)	missense	possibly damaging	0.64
R1606:Bltp1	UTSW	3	36,996,548 (GRCm39)	missense	probably damaging	1.00
R1638:Bltp1	UTSW	3	37,089,961 (GRCm39)	nonsense	probably null
R1772:Bltp1	UTSW	3	37,013,581 (GRCm39)	missense	probably damaging	1.00
R1896:Bltp1	UTSW	3	36,962,380 (GRCm39)	nonsense	probably null
R1919:Bltp1	UTSW	3	37,061,132 (GRCm39)	critical splice acceptor site	probably null
R1983:Bltp1	UTSW	3	36,942,014 (GRCm39)	missense	probably null	1.00
R1987:Bltp1	UTSW	3	37,008,134 (GRCm39)	critical splice donor site	probably null
R1992:Bltp1	UTSW	3	37,054,181 (GRCm39)	missense	probably benign	0.32
R1999:Bltp1	UTSW	3	36,962,360 (GRCm39)	missense	probably damaging	1.00
R2004:Bltp1	UTSW	3	36,949,527 (GRCm39)	missense	possibly damaging	0.77
R2010:Bltp1	UTSW	3	36,982,700 (GRCm39)	missense	probably benign	0.09
R2027:Bltp1	UTSW	3	37,102,110 (GRCm39)	splice site	probably benign
R2039:Bltp1	UTSW	3	37,058,027 (GRCm39)	missense	possibly damaging	0.66
R2054:Bltp1	UTSW	3	37,002,002 (GRCm39)	missense	probably benign	0.01
R2089:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,008,119 (GRCm39)	missense	probably damaging	1.00
R2220:Bltp1	UTSW	3	36,929,679 (GRCm39)	critical splice donor site	probably null
R2374:Bltp1	UTSW	3	36,939,545 (GRCm39)	missense	probably benign	0.00
R2437:Bltp1	UTSW	3	37,012,834 (GRCm39)	splice site	probably null
R2860:Bltp1	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
R2861:Bltp1	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
R2909:Bltp1	UTSW	3	37,002,102 (GRCm39)	missense	probably damaging	1.00
R2925:Bltp1	UTSW	3	37,061,271 (GRCm39)	missense	probably damaging	0.99
R2940:Bltp1	UTSW	3	37,012,954 (GRCm39)	missense	probably damaging	1.00
R3015:Bltp1	UTSW	3	36,929,611 (GRCm39)	missense	probably damaging	1.00
R3086:Bltp1	UTSW	3	37,065,852 (GRCm39)	missense	possibly damaging	0.56
R3159:Bltp1	UTSW	3	37,013,564 (GRCm39)	missense	probably benign	0.17
R3440:Bltp1	UTSW	3	37,096,061 (GRCm39)	nonsense	probably null
R3703:Bltp1	UTSW	3	37,041,730 (GRCm39)	missense	probably damaging	1.00
R3705:Bltp1	UTSW	3	37,041,730 (GRCm39)	missense	probably damaging	1.00
R3795:Bltp1	UTSW	3	37,084,714 (GRCm39)	missense	probably benign	0.30
R3820:Bltp1	UTSW	3	37,094,583 (GRCm39)	missense	probably damaging	1.00
R3862:Bltp1	UTSW	3	36,939,547 (GRCm39)	missense	possibly damaging	0.73
R3944:Bltp1	UTSW	3	37,084,210 (GRCm39)	missense	possibly damaging	0.90
R4020:Bltp1	UTSW	3	37,066,724 (GRCm39)	intron	probably benign
R4091:Bltp1	UTSW	3	37,084,738 (GRCm39)	missense	probably benign	0.00
R4159:Bltp1	UTSW	3	36,985,232 (GRCm39)	missense	probably benign	0.00
R4231:Bltp1	UTSW	3	36,974,385 (GRCm39)	missense	probably benign	0.10
R4368:Bltp1	UTSW	3	37,042,296 (GRCm39)	nonsense	probably null
R4413:Bltp1	UTSW	3	37,012,830 (GRCm39)	splice site	probably null
R4475:Bltp1	UTSW	3	37,094,544 (GRCm39)	missense	probably damaging	1.00
R4488:Bltp1	UTSW	3	37,058,082 (GRCm39)	missense	probably null	0.93
R4489:Bltp1	UTSW	3	37,058,082 (GRCm39)	missense	probably null	0.93
R4516:Bltp1	UTSW	3	36,949,460 (GRCm39)	missense	possibly damaging	0.90
R4580:Bltp1	UTSW	3	37,084,174 (GRCm39)	missense	probably benign	0.02
R4672:Bltp1	UTSW	3	36,944,139 (GRCm39)	makesense	probably null
R4705:Bltp1	UTSW	3	37,096,038 (GRCm39)	missense	probably benign	0.03
R4741:Bltp1	UTSW	3	36,996,524 (GRCm39)	missense	probably damaging	0.99
R4754:Bltp1	UTSW	3	37,076,615 (GRCm39)	nonsense	probably null
R4778:Bltp1	UTSW	3	36,991,214 (GRCm39)	missense	possibly damaging	0.90
R4833:Bltp1	UTSW	3	37,019,117 (GRCm39)	missense	probably damaging	0.96
R4896:Bltp1	UTSW	3	37,020,086 (GRCm39)	missense	probably damaging	1.00
R4910:Bltp1	UTSW	3	37,052,348 (GRCm39)	missense	probably damaging	1.00
R4922:Bltp1	UTSW	3	37,041,314 (GRCm39)	missense	probably damaging	1.00
R4941:Bltp1	UTSW	3	36,974,050 (GRCm39)	missense	probably benign	0.41
R4941:Bltp1	UTSW	3	36,971,851 (GRCm39)	missense	probably damaging	1.00
R4980:Bltp1	UTSW	3	36,997,461 (GRCm39)	missense	probably damaging	1.00
R5030:Bltp1	UTSW	3	36,997,548 (GRCm39)	intron	probably benign
R5049:Bltp1	UTSW	3	37,095,539 (GRCm39)	missense	probably damaging	1.00
R5049:Bltp1	UTSW	3	37,094,655 (GRCm39)	intron	probably benign
R5089:Bltp1	UTSW	3	37,041,651 (GRCm39)	missense	probably benign	0.02
R5092:Bltp1	UTSW	3	37,054,234 (GRCm39)	missense	probably benign	0.14
R5122:Bltp1	UTSW	3	37,088,906 (GRCm39)	splice site	probably null
R5210:Bltp1	UTSW	3	37,087,414 (GRCm39)	missense	possibly damaging	0.85
R5246:Bltp1	UTSW	3	37,102,199 (GRCm39)	missense	probably damaging	1.00
R5289:Bltp1	UTSW	3	37,054,258 (GRCm39)	missense	probably damaging	0.97
R5348:Bltp1	UTSW	3	37,102,295 (GRCm39)	missense	probably damaging	1.00
R5394:Bltp1	UTSW	3	36,971,817 (GRCm39)	missense	probably damaging	1.00
R5434:Bltp1	UTSW	3	36,929,665 (GRCm39)	missense	probably damaging	1.00
R5667:Bltp1	UTSW	3	36,971,826 (GRCm39)	missense	probably benign	0.00
R5686:Bltp1	UTSW	3	36,971,809 (GRCm39)	missense	probably benign	0.00
R5701:Bltp1	UTSW	3	36,975,509 (GRCm39)	missense	probably benign	0.10
R5778:Bltp1	UTSW	3	37,012,863 (GRCm39)	missense	probably damaging	1.00
R5787:Bltp1	UTSW	3	37,046,882 (GRCm39)	splice site	probably null
R5800:Bltp1	UTSW	3	37,106,592 (GRCm39)	missense	probably damaging	1.00
R5819:Bltp1	UTSW	3	37,102,749 (GRCm39)	missense	probably benign	0.12
R5820:Bltp1	UTSW	3	37,093,675 (GRCm39)	missense	probably benign	0.00
R5952:Bltp1	UTSW	3	37,019,770 (GRCm39)	missense	probably damaging	1.00
R5975:Bltp1	UTSW	3	37,023,370 (GRCm39)	missense	possibly damaging	0.64
R5996:Bltp1	UTSW	3	36,985,265 (GRCm39)	missense	probably benign	0.07
R6192:Bltp1	UTSW	3	37,042,318 (GRCm39)	missense	probably benign	0.00
R6225:Bltp1	UTSW	3	37,002,453 (GRCm39)	missense	probably damaging	1.00
R6234:Bltp1	UTSW	3	37,037,620 (GRCm39)	missense	probably benign	0.00
R6244:Bltp1	UTSW	3	37,011,148 (GRCm39)	missense	probably benign
R6263:Bltp1	UTSW	3	36,985,260 (GRCm39)	missense	probably benign	0.06
R6351:Bltp1	UTSW	3	36,962,377 (GRCm39)	missense	probably damaging	1.00
R6380:Bltp1	UTSW	3	37,087,456 (GRCm39)	missense	probably benign	0.19
R6468:Bltp1	UTSW	3	37,062,592 (GRCm39)	missense	probably damaging	1.00
R6759:Bltp1	UTSW	3	37,042,234 (GRCm39)	missense	possibly damaging	0.81
R6792:Bltp1	UTSW	3	37,065,715 (GRCm39)	critical splice acceptor site	probably null
R6809:Bltp1	UTSW	3	36,928,431 (GRCm39)	missense	probably damaging	0.98
R6841:Bltp1	UTSW	3	37,075,630 (GRCm39)	missense	probably damaging	1.00
R6959:Bltp1	UTSW	3	37,021,338 (GRCm39)	missense	probably damaging	1.00
R7102:Bltp1	UTSW	3	36,994,947 (GRCm39)	missense	probably damaging	0.99
R7188:Bltp1	UTSW	3	37,004,162 (GRCm39)	missense	probably benign	0.06
R7212:Bltp1	UTSW	3	37,102,158 (GRCm39)	missense
R7425:Bltp1	UTSW	3	37,037,543 (GRCm39)	missense	probably benign	0.02
R7425:Bltp1	UTSW	3	37,002,490 (GRCm39)	missense	probably benign
R7451:Bltp1	UTSW	3	37,076,956 (GRCm39)	splice site	probably null
R7604:Bltp1	UTSW	3	37,003,992 (GRCm39)	splice site	probably null
R7622:Bltp1	UTSW	3	37,002,562 (GRCm39)	nonsense	probably null
R7671:Bltp1	UTSW	3	36,997,380 (GRCm39)	missense	probably damaging	0.99
R7699:Bltp1	UTSW	3	37,080,303 (GRCm39)	missense	probably benign	0.00
R7699:Bltp1	UTSW	3	37,028,321 (GRCm39)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,028,321 (GRCm39)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,080,303 (GRCm39)	missense	probably benign	0.00
R7748:Bltp1	UTSW	3	37,013,484 (GRCm39)	critical splice acceptor site	probably null
R7767:Bltp1	UTSW	3	36,974,436 (GRCm39)	critical splice donor site	probably null
R7787:Bltp1	UTSW	3	36,939,557 (GRCm39)	missense	probably damaging	1.00
R7830:Bltp1	UTSW	3	37,019,081 (GRCm39)	frame shift	probably null
R7849:Bltp1	UTSW	3	37,080,477 (GRCm39)	missense
R7912:Bltp1	UTSW	3	37,061,218 (GRCm39)	missense	probably damaging	0.99
R7914:Bltp1	UTSW	3	37,000,432 (GRCm39)	missense	probably benign	0.13
R7945:Bltp1	UTSW	3	37,020,042 (GRCm39)	missense	probably benign	0.03
R8039:Bltp1	UTSW	3	36,997,363 (GRCm39)	missense	probably benign	0.12
R8101:Bltp1	UTSW	3	37,062,651 (GRCm39)	missense	probably damaging	1.00
R8143:Bltp1	UTSW	3	37,000,657 (GRCm39)	critical splice donor site	probably null
R8145:Bltp1	UTSW	3	37,052,416 (GRCm39)	missense	probably damaging	1.00
R8171:Bltp1	UTSW	3	37,029,862 (GRCm39)	missense	probably benign	0.00
R8210:Bltp1	UTSW	3	37,067,030 (GRCm39)	missense
R8250:Bltp1	UTSW	3	36,971,811 (GRCm39)	missense	probably damaging	0.99
R8369:Bltp1	UTSW	3	37,065,752 (GRCm39)	missense
R8478:Bltp1	UTSW	3	37,087,426 (GRCm39)	missense	possibly damaging	0.74
R8558:Bltp1	UTSW	3	37,102,750 (GRCm39)	missense
R8688:Bltp1	UTSW	3	37,090,066 (GRCm39)	missense
R8724:Bltp1	UTSW	3	36,945,042 (GRCm39)	missense	probably damaging	0.99
R8818:Bltp1	UTSW	3	37,050,697 (GRCm39)	missense	possibly damaging	0.60
R8869:Bltp1	UTSW	3	37,013,007 (GRCm39)	missense	probably damaging	0.99
R8887:Bltp1	UTSW	3	37,087,503 (GRCm39)	missense	possibly damaging	0.95
R8899:Bltp1	UTSW	3	37,042,429 (GRCm39)	missense	probably damaging	1.00
R8907:Bltp1	UTSW	3	37,002,295 (GRCm39)	nonsense	probably null
R8960:Bltp1	UTSW	3	37,067,132 (GRCm39)	missense	probably damaging	1.00
R8990:Bltp1	UTSW	3	36,975,370 (GRCm39)	missense	possibly damaging	0.60
R9021:Bltp1	UTSW	3	37,052,493 (GRCm39)	missense	probably benign	0.00
R9048:Bltp1	UTSW	3	37,065,926 (GRCm39)	missense
R9100:Bltp1	UTSW	3	37,098,907 (GRCm39)	missense
R9166:Bltp1	UTSW	3	37,041,516 (GRCm39)	missense	probably damaging	1.00
R9176:Bltp1	UTSW	3	37,010,852 (GRCm39)	missense	possibly damaging	0.82
R9202:Bltp1	UTSW	3	36,944,970 (GRCm39)	missense	probably benign
R9303:Bltp1	UTSW	3	37,098,969 (GRCm39)	missense
R9305:Bltp1	UTSW	3	37,098,969 (GRCm39)	missense
R9332:Bltp1	UTSW	3	37,104,989 (GRCm39)	missense
R9362:Bltp1	UTSW	3	37,011,162 (GRCm39)	missense	probably benign
R9493:Bltp1	UTSW	3	37,065,885 (GRCm39)	missense
R9534:Bltp1	UTSW	3	37,052,419 (GRCm39)	missense	probably benign	0.01
R9569:Bltp1	UTSW	3	37,066,770 (GRCm39)	missense
R9593:Bltp1	UTSW	3	37,002,090 (GRCm39)	missense	probably damaging	1.00
R9600:Bltp1	UTSW	3	37,095,565 (GRCm39)	nonsense	probably null
R9733:Bltp1	UTSW	3	37,102,732 (GRCm39)	missense
R9751:Bltp1	UTSW	3	37,065,889 (GRCm39)	missense
RF013:Bltp1	UTSW	3	37,104,906 (GRCm39)	critical splice acceptor site	probably benign
RF015:Bltp1	UTSW	3	37,104,897 (GRCm39)	critical splice acceptor site	probably benign
RF021:Bltp1	UTSW	3	37,104,897 (GRCm39)	critical splice acceptor site	probably benign
RF023:Bltp1	UTSW	3	37,104,909 (GRCm39)	critical splice acceptor site	probably benign
RF034:Bltp1	UTSW	3	37,104,909 (GRCm39)	critical splice acceptor site	probably benign
RF035:Bltp1	UTSW	3	37,104,907 (GRCm39)	critical splice acceptor site	probably benign
RF055:Bltp1	UTSW	3	37,104,906 (GRCm39)	critical splice acceptor site	probably benign
X0050:Bltp1	UTSW	3	37,011,277 (GRCm39)	missense	probably damaging	1.00
Z1088:Bltp1	UTSW	3	37,041,716 (GRCm39)	missense	probably damaging	1.00
Z1177:Bltp1	UTSW	3	37,037,589 (GRCm39)	missense	possibly damaging	0.88
Z1177:Bltp1	UTSW	3	36,974,099 (GRCm39)	missense	probably benign
Z1177:Bltp1	UTSW	3	37,090,856 (GRCm39)	missense

Predicted Primers

PCR Primer
(F):5'- CTGTAGGTCTTTTGGAAAACAATGG -3'
(R):5'- TGTCAGGTATCTGCACTGGAAAG -3'

Sequencing Primer
(F):5'- AGGTTTATGAAGAAGCTGG -3'
(R):5'- TATCTGCACTGGAAAGCCAAG -3'

Posted On

2015-11-11