Incidental Mutation 'R4745:Itsn2'
| ID |
356672 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Itsn2
|
| Ensembl Gene |
ENSMUSG00000020640 |
| Gene Name |
intersectin 2 |
| Synonyms |
Sh3d1B, Sh3p18, Ese2, Eh domain, SH3 domain regulator of endocytosis 2 |
| MMRRC Submission |
042028-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4745 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
4642792-4763952 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 4711944 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 904
(D904G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000151896
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062580]
[ENSMUST00000219007]
[ENSMUST00000220311]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000062580
AA Change: D877G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000052758
Gene: ENSMUSG00000020640
AA Change: D877G
| Domain | Start | End | E-Value | Type |
|---|
|
EH
|
15 |
109 |
8.44e-41 |
SMART |
|
EFh
|
58 |
86 |
7.18e-3 |
SMART |
|
low complexity region
|
156 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
231 |
N/A |
INTRINSIC |
|
EH
|
238 |
333 |
4.06e-43 |
SMART |
|
EFh
|
282 |
310 |
6.16e-2 |
SMART |
|
coiled coil region
|
366 |
462 |
N/A |
INTRINSIC |
|
coiled coil region
|
516 |
556 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
715 |
N/A |
INTRINSIC |
|
SH3
|
721 |
778 |
2.65e-21 |
SMART |
|
low complexity region
|
791 |
811 |
N/A |
INTRINSIC |
|
SH3
|
855 |
909 |
8.83e-18 |
SMART |
|
SH3
|
945 |
999 |
9.1e-20 |
SMART |
|
SH3
|
1017 |
1077 |
1.55e-13 |
SMART |
|
SH3
|
1091 |
1146 |
7.22e-23 |
SMART |
|
RhoGEF
|
1174 |
1355 |
1.93e-56 |
SMART |
|
PH
|
1396 |
1507 |
1.16e-9 |
SMART |
|
C2
|
1531 |
1628 |
3.96e-19 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000217672
AA Change: D435G
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218072
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218985
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000219007
AA Change: D877G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219832
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000220311
AA Change: D904G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Meta Mutation Damage Score |
0.7495 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 94.8%
|
| Validation Efficiency |
97% (89/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal brain morphology and function and behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca17 |
T |
C |
17: 24,526,427 (GRCm39) |
Y619C |
probably damaging |
Het |
| Adck1 |
A |
G |
12: 88,368,949 (GRCm39) |
|
probably null |
Het |
| Agap3 |
A |
C |
5: 24,656,123 (GRCm39) |
|
probably null |
Het |
| Ankib1 |
A |
T |
5: 3,782,566 (GRCm39) |
H354Q |
probably damaging |
Het |
| Ankrd29 |
T |
G |
18: 12,387,679 (GRCm39) |
N301T |
probably benign |
Het |
| Arhgef4 |
A |
G |
1: 34,846,356 (GRCm39) |
T379A |
probably damaging |
Het |
| Arid1a |
A |
G |
4: 133,480,417 (GRCm39) |
V169A |
probably benign |
Het |
| Bag2 |
T |
C |
1: 33,787,417 (GRCm39) |
|
probably null |
Het |
| Bmt2 |
A |
C |
6: 13,628,686 (GRCm39) |
Y332* |
probably null |
Het |
| Bpifb1 |
A |
T |
2: 154,053,501 (GRCm39) |
K248* |
probably null |
Het |
| Caap1 |
C |
A |
4: 94,444,751 (GRCm39) |
|
probably null |
Het |
| Calcr |
T |
A |
6: 3,692,576 (GRCm39) |
Y389F |
probably damaging |
Het |
| Capn1 |
C |
T |
19: 6,043,946 (GRCm39) |
V562I |
probably benign |
Het |
| Ccr1 |
T |
A |
9: 123,763,985 (GRCm39) |
T182S |
probably benign |
Het |
| Ceacam15 |
T |
C |
7: 16,407,259 (GRCm39) |
D86G |
probably benign |
Het |
| Cldnd1 |
C |
T |
16: 58,550,006 (GRCm39) |
T63I |
probably benign |
Het |
| Col12a1 |
A |
T |
9: 79,559,368 (GRCm39) |
|
probably null |
Het |
| Cystm1 |
A |
G |
18: 36,526,348 (GRCm39) |
|
probably benign |
Het |
| Ddx55 |
T |
A |
5: 124,705,028 (GRCm39) |
Y428* |
probably null |
Het |
| Ensa |
G |
A |
3: 95,538,745 (GRCm39) |
G118D |
probably benign |
Het |
| Folh1 |
A |
T |
7: 86,372,482 (GRCm39) |
|
probably null |
Het |
| Foxj2 |
C |
A |
6: 122,814,948 (GRCm39) |
P328Q |
probably damaging |
Het |
| Fscn3 |
A |
G |
6: 28,435,627 (GRCm39) |
I417V |
probably damaging |
Het |
| Galnt7 |
T |
C |
8: 57,995,761 (GRCm39) |
|
probably benign |
Het |
| Gm11563 |
T |
A |
11: 99,549,246 (GRCm39) |
*169C |
probably null |
Het |
| Hfm1 |
A |
T |
5: 107,049,709 (GRCm39) |
D417E |
possibly damaging |
Het |
| Ighv15-2 |
A |
G |
12: 114,528,230 (GRCm39) |
S107P |
probably damaging |
Het |
| Kif1b |
A |
T |
4: 149,322,339 (GRCm39) |
L860* |
probably null |
Het |
| Krt79 |
T |
C |
15: 101,839,119 (GRCm39) |
E450G |
probably damaging |
Het |
| Lama1 |
T |
C |
17: 68,045,775 (GRCm39) |
S227P |
probably damaging |
Het |
| Lamp5 |
C |
A |
2: 135,902,786 (GRCm39) |
H168Q |
probably benign |
Het |
| Lilra5 |
A |
T |
7: 4,245,076 (GRCm39) |
Q240L |
possibly damaging |
Het |
| Lrp1 |
A |
T |
10: 127,385,813 (GRCm39) |
C3521S |
probably benign |
Het |
| Mroh1 |
T |
A |
15: 76,292,730 (GRCm39) |
|
probably null |
Het |
| Nlrp4g |
A |
T |
9: 124,349,515 (GRCm38) |
|
noncoding transcript |
Het |
| Nr2f6 |
A |
T |
8: 71,831,179 (GRCm39) |
I70N |
probably benign |
Het |
| Nr4a2 |
T |
A |
2: 57,000,163 (GRCm39) |
D311V |
probably damaging |
Het |
| Odad2 |
G |
A |
18: 7,286,763 (GRCm39) |
T156M |
probably benign |
Het |
| Or10w1 |
T |
A |
19: 13,632,750 (GRCm39) |
M319K |
probably benign |
Het |
| Or10x4 |
T |
C |
1: 174,219,442 (GRCm39) |
L269P |
probably damaging |
Het |
| Or52n20 |
T |
A |
7: 104,320,711 (GRCm39) |
F267L |
probably damaging |
Het |
| Pcdhb6 |
C |
A |
18: 37,468,426 (GRCm39) |
A449D |
possibly damaging |
Het |
| Pcgf6 |
A |
G |
19: 47,036,545 (GRCm39) |
|
probably null |
Het |
| Prc1 |
C |
A |
7: 79,962,911 (GRCm39) |
H131Q |
probably benign |
Het |
| Ptprq |
C |
A |
10: 107,360,114 (GRCm39) |
R2187L |
probably damaging |
Het |
| Rasl2-9 |
C |
A |
7: 5,128,702 (GRCm39) |
R76L |
possibly damaging |
Het |
| Rdh16f1 |
A |
T |
10: 127,626,685 (GRCm39) |
Y246F |
probably benign |
Het |
| Rit1 |
T |
C |
3: 88,624,982 (GRCm39) |
|
probably benign |
Het |
| Sash1 |
A |
G |
10: 8,605,672 (GRCm39) |
V906A |
probably benign |
Het |
| Scnn1b |
T |
C |
7: 121,501,509 (GRCm39) |
V108A |
probably benign |
Het |
| Sema4f |
A |
T |
6: 82,895,265 (GRCm39) |
I356N |
probably damaging |
Het |
| Shc4 |
A |
T |
2: 125,491,197 (GRCm39) |
L447Q |
probably damaging |
Het |
| Slc24a1 |
T |
C |
9: 64,856,758 (GRCm39) |
M50V |
unknown |
Het |
| Slc28a3 |
T |
A |
13: 58,722,077 (GRCm39) |
D269V |
possibly damaging |
Het |
| Slc35e1 |
A |
G |
8: 73,246,166 (GRCm39) |
S89P |
possibly damaging |
Het |
| Smpd5 |
T |
A |
15: 76,179,008 (GRCm39) |
H125Q |
probably benign |
Het |
| Snapc2 |
A |
G |
8: 4,304,578 (GRCm39) |
T31A |
probably damaging |
Het |
| Sox5 |
G |
C |
6: 143,779,214 (GRCm39) |
H606D |
possibly damaging |
Het |
| Spag6 |
A |
G |
2: 18,742,107 (GRCm39) |
T367A |
possibly damaging |
Het |
| Spag8 |
T |
C |
4: 43,651,636 (GRCm39) |
T413A |
probably damaging |
Het |
| Sptlc3 |
G |
A |
2: 139,389,087 (GRCm39) |
G156R |
probably damaging |
Het |
| Stx19 |
A |
G |
16: 62,642,783 (GRCm39) |
T200A |
probably benign |
Het |
| Tas2r116 |
A |
G |
6: 132,832,668 (GRCm39) |
T90A |
probably benign |
Het |
| Tasor2 |
G |
A |
13: 3,640,069 (GRCm39) |
T356I |
probably benign |
Het |
| Tbl3 |
A |
G |
17: 24,924,304 (GRCm39) |
|
probably benign |
Het |
| Tekt5 |
G |
T |
16: 10,213,058 (GRCm39) |
P76T |
probably damaging |
Het |
| Tjp2 |
C |
T |
19: 24,074,030 (GRCm39) |
E1086K |
possibly damaging |
Het |
| Topbp1 |
T |
C |
9: 103,200,770 (GRCm39) |
L601P |
probably damaging |
Het |
| Trav16 |
T |
A |
14: 53,980,934 (GRCm39) |
M41K |
possibly damaging |
Het |
| Trav6-5 |
C |
A |
14: 53,728,960 (GRCm39) |
N72K |
probably benign |
Het |
| Trpm3 |
C |
G |
19: 22,692,659 (GRCm39) |
T250S |
possibly damaging |
Het |
| Vps35 |
A |
T |
8: 85,987,891 (GRCm39) |
D753E |
probably benign |
Het |
| Vstm2a |
A |
T |
11: 16,213,061 (GRCm39) |
N149Y |
probably damaging |
Het |
| Vwa2 |
G |
T |
19: 56,895,318 (GRCm39) |
M497I |
probably benign |
Het |
| Zfat |
C |
A |
15: 68,052,223 (GRCm39) |
V517L |
probably benign |
Het |
| Zfp169 |
C |
A |
13: 48,643,708 (GRCm39) |
R473L |
possibly damaging |
Het |
| Zfp672 |
T |
C |
11: 58,220,324 (GRCm39) |
|
probably benign |
Het |
| Zranb1 |
T |
C |
7: 132,574,443 (GRCm39) |
V420A |
probably damaging |
Het |
|
| Other mutations in Itsn2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00341:Itsn2
|
APN |
12 |
4,708,027 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00647:Itsn2
|
APN |
12 |
4,663,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL00933:Itsn2
|
APN |
12 |
4,757,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01686:Itsn2
|
APN |
12 |
4,686,693 (GRCm39) |
splice site |
probably benign |
|
|
IGL01873:Itsn2
|
APN |
12 |
4,682,366 (GRCm39) |
splice site |
probably benign |
|
|
IGL02200:Itsn2
|
APN |
12 |
4,686,632 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02280:Itsn2
|
APN |
12 |
4,758,961 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02388:Itsn2
|
APN |
12 |
4,679,557 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02938:Itsn2
|
APN |
12 |
4,747,216 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Gopher
|
UTSW |
12 |
4,756,983 (GRCm39) |
nonsense |
probably null |
|
|
inversus
|
UTSW |
12 |
4,689,670 (GRCm39) |
nonsense |
probably null |
|
|
Liberator
|
UTSW |
12 |
4,716,176 (GRCm39) |
nonsense |
probably null |
|
|
rolled
|
UTSW |
12 |
4,684,792 (GRCm39) |
nonsense |
probably null |
|
|
Stratofortress
|
UTSW |
12 |
4,674,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Underground
|
UTSW |
12 |
4,751,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Vole
|
UTSW |
12 |
4,723,420 (GRCm39) |
nonsense |
probably null |
|
|
R0101:Itsn2
|
UTSW |
12 |
4,683,058 (GRCm39) |
unclassified |
probably benign |
|
|
R0268:Itsn2
|
UTSW |
12 |
4,750,333 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0584:Itsn2
|
UTSW |
12 |
4,747,180 (GRCm39) |
missense |
probably benign |
|
|
R0604:Itsn2
|
UTSW |
12 |
4,708,189 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0639:Itsn2
|
UTSW |
12 |
4,762,556 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0738:Itsn2
|
UTSW |
12 |
4,685,681 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1132:Itsn2
|
UTSW |
12 |
4,708,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1163:Itsn2
|
UTSW |
12 |
4,762,009 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1169:Itsn2
|
UTSW |
12 |
4,689,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1258:Itsn2
|
UTSW |
12 |
4,723,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1297:Itsn2
|
UTSW |
12 |
4,750,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1423:Itsn2
|
UTSW |
12 |
4,723,572 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1572:Itsn2
|
UTSW |
12 |
4,700,044 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1601:Itsn2
|
UTSW |
12 |
4,708,452 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1628:Itsn2
|
UTSW |
12 |
4,679,652 (GRCm39) |
missense |
probably benign |
|
|
R1650:Itsn2
|
UTSW |
12 |
4,687,767 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1752:Itsn2
|
UTSW |
12 |
4,761,950 (GRCm39) |
splice site |
probably null |
|
|
R1758:Itsn2
|
UTSW |
12 |
4,708,160 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1942:Itsn2
|
UTSW |
12 |
4,689,670 (GRCm39) |
nonsense |
probably null |
|
|
R1976:Itsn2
|
UTSW |
12 |
4,722,733 (GRCm39) |
splice site |
probably benign |
|
|
R2000:Itsn2
|
UTSW |
12 |
4,716,176 (GRCm39) |
nonsense |
probably null |
|
|
R2060:Itsn2
|
UTSW |
12 |
4,677,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2119:Itsn2
|
UTSW |
12 |
4,757,025 (GRCm39) |
missense |
probably benign |
0.32 |
|
R2168:Itsn2
|
UTSW |
12 |
4,683,044 (GRCm39) |
unclassified |
probably benign |
|
|
R2394:Itsn2
|
UTSW |
12 |
4,757,005 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R2860:Itsn2
|
UTSW |
12 |
4,750,315 (GRCm39) |
splice site |
probably benign |
|
|
R2861:Itsn2
|
UTSW |
12 |
4,750,315 (GRCm39) |
splice site |
probably benign |
|
|
R2900:Itsn2
|
UTSW |
12 |
4,680,713 (GRCm39) |
unclassified |
probably benign |
|
|
R2991:Itsn2
|
UTSW |
12 |
4,708,474 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3087:Itsn2
|
UTSW |
12 |
4,716,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3881:Itsn2
|
UTSW |
12 |
4,684,546 (GRCm39) |
unclassified |
probably benign |
|
|
R4022:Itsn2
|
UTSW |
12 |
4,674,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Itsn2
|
UTSW |
12 |
4,762,611 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4657:Itsn2
|
UTSW |
12 |
4,763,197 (GRCm39) |
makesense |
probably null |
|
|
R4727:Itsn2
|
UTSW |
12 |
4,757,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4770:Itsn2
|
UTSW |
12 |
4,677,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4905:Itsn2
|
UTSW |
12 |
4,684,583 (GRCm39) |
unclassified |
probably benign |
|
|
R5269:Itsn2
|
UTSW |
12 |
4,683,553 (GRCm39) |
unclassified |
probably benign |
|
|
R5314:Itsn2
|
UTSW |
12 |
4,677,960 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5345:Itsn2
|
UTSW |
12 |
4,722,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5399:Itsn2
|
UTSW |
12 |
4,703,535 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5566:Itsn2
|
UTSW |
12 |
4,676,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5725:Itsn2
|
UTSW |
12 |
4,680,767 (GRCm39) |
unclassified |
probably benign |
|
|
R5773:Itsn2
|
UTSW |
12 |
4,757,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6116:Itsn2
|
UTSW |
12 |
4,679,939 (GRCm39) |
unclassified |
probably benign |
|
|
R6254:Itsn2
|
UTSW |
12 |
4,674,982 (GRCm39) |
splice site |
probably null |
|
|
R6325:Itsn2
|
UTSW |
12 |
4,756,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6361:Itsn2
|
UTSW |
12 |
4,679,655 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6456:Itsn2
|
UTSW |
12 |
4,679,923 (GRCm39) |
unclassified |
probably benign |
|
|
R6494:Itsn2
|
UTSW |
12 |
4,684,792 (GRCm39) |
nonsense |
probably null |
|
|
R6854:Itsn2
|
UTSW |
12 |
4,702,382 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6941:Itsn2
|
UTSW |
12 |
4,679,641 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6961:Itsn2
|
UTSW |
12 |
4,723,420 (GRCm39) |
nonsense |
probably null |
|
|
R7326:Itsn2
|
UTSW |
12 |
4,682,985 (GRCm39) |
missense |
unknown |
|
|
R7387:Itsn2
|
UTSW |
12 |
4,689,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7465:Itsn2
|
UTSW |
12 |
4,756,983 (GRCm39) |
nonsense |
probably null |
|
|
R7471:Itsn2
|
UTSW |
12 |
4,758,198 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7814:Itsn2
|
UTSW |
12 |
4,708,561 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7854:Itsn2
|
UTSW |
12 |
4,751,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7879:Itsn2
|
UTSW |
12 |
4,751,265 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7990:Itsn2
|
UTSW |
12 |
4,685,629 (GRCm39) |
missense |
unknown |
|
|
R8009:Itsn2
|
UTSW |
12 |
4,714,553 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8115:Itsn2
|
UTSW |
12 |
4,723,602 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8143:Itsn2
|
UTSW |
12 |
4,683,003 (GRCm39) |
missense |
unknown |
|
|
R8248:Itsn2
|
UTSW |
12 |
4,712,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8735:Itsn2
|
UTSW |
12 |
4,721,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8748:Itsn2
|
UTSW |
12 |
4,751,337 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9018:Itsn2
|
UTSW |
12 |
4,708,091 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9386:Itsn2
|
UTSW |
12 |
4,679,730 (GRCm39) |
missense |
unknown |
|
|
R9681:Itsn2
|
UTSW |
12 |
4,683,499 (GRCm39) |
missense |
unknown |
|
|
Z1088:Itsn2
|
UTSW |
12 |
4,762,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGTGCTGTGATGAAGTGGC -3'
(R):5'- GCTCATGTGGTAAGGACACC -3'
Sequencing Primer
(F):5'- AAGGCGACTCACATGGCTG -3'
(R):5'- TGGTAAGGACACCAGCGTC -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation