Incidental Mutation 'R4747:Ercc6'
| ID |
357219 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ercc6
|
| Ensembl Gene |
ENSMUSG00000054051 |
| Gene Name |
excision repair cross-complementing rodent repair deficiency, complementation group 6 |
| Synonyms |
CS group B correcting gene, C130058G22Rik, CSB |
| MMRRC Submission |
042029-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.422)
|
| Stock # |
R4747 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
32235478-32302947 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 32291864 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1076
(V1076A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066256
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066807]
|
| AlphaFold |
F8VPZ5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000066807
AA Change: V1076A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000066256
Gene: ENSMUSG00000054051
AA Change: V1076A
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:4CVO|A
|
82 |
160 |
1e-36 |
PDB |
|
low complexity region
|
286 |
299 |
N/A |
INTRINSIC |
|
low complexity region
|
361 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
434 |
N/A |
INTRINSIC |
|
low complexity region
|
460 |
469 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
491 |
N/A |
INTRINSIC |
|
DEXDc
|
499 |
699 |
8.34e-33 |
SMART |
|
Blast:DEXDc
|
720 |
821 |
7e-56 |
BLAST |
|
HELICc
|
865 |
948 |
1.41e-21 |
SMART |
|
low complexity region
|
1364 |
1377 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228549
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. [provided by RefSeq, Mar 2016]
PHENOTYPE: Homozygous mutant mice exhibit UV sensitivity, inactivation of transcription-coupled repair, increased incidence of induced skin and eye tumors, circling behavior, impaired coordination and lower body weight. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933402D24Rik |
A |
G |
1: 63,795,568 (GRCm39) |
|
probably benign |
Het |
| Acadvl |
G |
T |
11: 69,903,334 (GRCm39) |
N340K |
probably damaging |
Het |
| Adgrl4 |
T |
A |
3: 151,213,077 (GRCm39) |
N372K |
probably benign |
Het |
| Adh1 |
G |
A |
3: 137,994,642 (GRCm39) |
G321S |
probably damaging |
Het |
| Ankrd26 |
G |
T |
6: 118,504,718 (GRCm39) |
N730K |
probably benign |
Het |
| Aoc2 |
A |
T |
11: 101,219,646 (GRCm39) |
|
probably null |
Het |
| Arhgef4 |
A |
G |
1: 34,762,355 (GRCm39) |
E537G |
unknown |
Het |
| Ccdc7b |
T |
C |
8: 129,904,716 (GRCm39) |
V118A |
probably benign |
Het |
| Ccdc88b |
T |
A |
19: 6,833,509 (GRCm39) |
R219W |
probably damaging |
Het |
| Ccdc97 |
T |
C |
7: 25,418,348 (GRCm39) |
|
probably null |
Het |
| Cfhr4 |
A |
T |
1: 139,625,922 (GRCm39) |
C792S |
probably damaging |
Het |
| Ciao3 |
A |
T |
17: 25,999,327 (GRCm39) |
Y247F |
probably benign |
Het |
| Cnot1 |
T |
C |
8: 96,501,310 (GRCm39) |
N86S |
probably benign |
Het |
| Comp |
T |
C |
8: 70,829,352 (GRCm39) |
C310R |
probably damaging |
Het |
| Crtc2 |
A |
T |
3: 90,167,518 (GRCm39) |
N281Y |
probably damaging |
Het |
| Cryl1 |
T |
C |
14: 57,550,559 (GRCm39) |
K102E |
probably damaging |
Het |
| Csf2ra |
G |
A |
19: 61,214,491 (GRCm39) |
R225* |
probably null |
Het |
| Dao |
A |
T |
5: 114,150,693 (GRCm39) |
D99V |
probably benign |
Het |
| Dgkd |
A |
G |
1: 87,861,889 (GRCm39) |
T815A |
probably damaging |
Het |
| Dhrs7 |
T |
C |
12: 72,699,892 (GRCm39) |
T247A |
probably benign |
Het |
| Dnah7c |
G |
C |
1: 46,572,328 (GRCm39) |
D934H |
probably damaging |
Het |
| Dnajc15 |
T |
C |
14: 78,081,896 (GRCm39) |
Y82C |
probably benign |
Het |
| Dnajc4 |
T |
C |
19: 6,966,872 (GRCm39) |
Q152R |
probably damaging |
Het |
| Dsc1 |
T |
C |
18: 20,227,615 (GRCm39) |
K541R |
probably damaging |
Het |
| Elp4 |
G |
A |
2: 105,624,952 (GRCm39) |
R196C |
probably damaging |
Het |
| Epha8 |
GC |
G |
4: 136,666,006 (GRCm39) |
|
probably null |
Het |
| Fgd4 |
T |
C |
16: 16,241,793 (GRCm39) |
Y677C |
probably damaging |
Het |
| Fndc3b |
C |
A |
3: 27,483,114 (GRCm39) |
C1028F |
probably damaging |
Het |
| Folr1 |
T |
A |
7: 101,513,184 (GRCm39) |
D37V |
probably damaging |
Het |
| Gabrr3 |
T |
A |
16: 59,268,277 (GRCm39) |
|
probably null |
Het |
| Garem1 |
C |
A |
18: 21,263,000 (GRCm39) |
V605L |
probably benign |
Het |
| Gbp7 |
A |
T |
3: 142,248,778 (GRCm39) |
D347V |
probably damaging |
Het |
| Gdpd4 |
A |
G |
7: 97,610,840 (GRCm39) |
T87A |
possibly damaging |
Het |
| Gm12258 |
C |
A |
11: 58,750,422 (GRCm39) |
H532Q |
probably damaging |
Het |
| Herc2 |
A |
G |
7: 55,756,141 (GRCm39) |
E727G |
possibly damaging |
Het |
| Hfm1 |
G |
A |
5: 107,065,389 (GRCm39) |
H97Y |
probably benign |
Het |
| Idua |
G |
T |
5: 108,828,902 (GRCm39) |
R335L |
probably damaging |
Het |
| Ifi207 |
A |
G |
1: 173,556,633 (GRCm39) |
S702P |
probably benign |
Het |
| Kif16b |
A |
T |
2: 142,699,346 (GRCm39) |
V78D |
probably damaging |
Het |
| Klra17 |
T |
A |
6: 129,849,232 (GRCm39) |
D114V |
probably damaging |
Het |
| Krt76 |
A |
G |
15: 101,794,180 (GRCm39) |
S481P |
probably damaging |
Het |
| Lhfpl5 |
A |
G |
17: 28,798,950 (GRCm39) |
D153G |
probably damaging |
Het |
| Med21 |
T |
A |
6: 146,550,700 (GRCm39) |
D70E |
possibly damaging |
Het |
| Mroh3 |
A |
T |
1: 136,113,237 (GRCm39) |
M739K |
probably benign |
Het |
| Myo1a |
A |
G |
10: 127,550,307 (GRCm39) |
E549G |
probably damaging |
Het |
| Neu1 |
A |
G |
17: 35,153,359 (GRCm39) |
D294G |
possibly damaging |
Het |
| Nmur2 |
A |
T |
11: 55,931,105 (GRCm39) |
I202K |
probably benign |
Het |
| Nop2 |
T |
A |
6: 125,114,057 (GRCm39) |
D174E |
probably benign |
Het |
| Ogfr |
A |
T |
2: 180,236,216 (GRCm39) |
H267L |
probably damaging |
Het |
| Or10p1 |
G |
T |
10: 129,444,053 (GRCm39) |
A99E |
possibly damaging |
Het |
| Or5m8 |
A |
G |
2: 85,822,271 (GRCm39) |
T37A |
probably damaging |
Het |
| P2ry13 |
T |
A |
3: 59,117,308 (GRCm39) |
I157F |
probably benign |
Het |
| Pank4 |
T |
C |
4: 155,063,989 (GRCm39) |
V660A |
probably damaging |
Het |
| Pax6 |
C |
A |
2: 105,526,847 (GRCm39) |
P251Q |
probably benign |
Het |
| Pcdhb13 |
T |
C |
18: 37,577,868 (GRCm39) |
Y749H |
probably damaging |
Het |
| Pcdhga3 |
C |
A |
18: 37,809,799 (GRCm39) |
Q751K |
probably benign |
Het |
| Pcnt |
C |
T |
10: 76,272,299 (GRCm39) |
E186K |
possibly damaging |
Het |
| Pecam1 |
A |
T |
11: 106,575,072 (GRCm39) |
F613I |
probably benign |
Het |
| Pias2 |
T |
C |
18: 77,240,488 (GRCm39) |
*615Q |
probably null |
Het |
| Plb1 |
A |
T |
5: 32,507,003 (GRCm39) |
M1193L |
probably benign |
Het |
| Pomgnt1 |
T |
C |
4: 116,013,396 (GRCm39) |
L506P |
probably damaging |
Het |
| Qrfp |
T |
C |
2: 31,698,852 (GRCm39) |
T27A |
probably damaging |
Het |
| Relb |
C |
A |
7: 19,361,847 (GRCm39) |
|
probably null |
Het |
| Resf1 |
A |
T |
6: 149,228,392 (GRCm39) |
E479D |
probably damaging |
Het |
| Rgl1 |
G |
T |
1: 152,400,450 (GRCm39) |
C685* |
probably null |
Het |
| Ric8b |
A |
G |
10: 84,753,628 (GRCm39) |
Y8C |
probably benign |
Het |
| Rrp36 |
G |
A |
17: 46,980,893 (GRCm39) |
A161V |
possibly damaging |
Het |
| Samd9l |
G |
A |
6: 3,375,504 (GRCm39) |
Q586* |
probably null |
Het |
| Sbf1 |
C |
T |
15: 89,186,916 (GRCm39) |
D821N |
probably damaging |
Het |
| Septin8 |
G |
C |
11: 53,427,545 (GRCm39) |
A255P |
probably damaging |
Het |
| Skp2 |
T |
C |
15: 9,113,927 (GRCm39) |
T329A |
possibly damaging |
Het |
| Slc15a2 |
C |
T |
16: 36,592,498 (GRCm39) |
V220M |
probably damaging |
Het |
| Slc25a11 |
T |
A |
11: 70,536,782 (GRCm39) |
T63S |
possibly damaging |
Het |
| Sowahc |
T |
C |
10: 59,058,983 (GRCm39) |
I373T |
probably benign |
Het |
| Sptbn2 |
T |
A |
19: 4,798,182 (GRCm39) |
M1969K |
probably benign |
Het |
| St14 |
G |
A |
9: 31,015,053 (GRCm39) |
T315M |
possibly damaging |
Het |
| Tagap |
G |
A |
17: 8,151,030 (GRCm39) |
R284H |
probably benign |
Het |
| Tdpoz3 |
T |
A |
3: 93,733,476 (GRCm39) |
S50R |
possibly damaging |
Het |
| Thoc5 |
A |
G |
11: 4,854,187 (GRCm39) |
D182G |
probably damaging |
Het |
| Tinag |
A |
G |
9: 76,904,238 (GRCm39) |
V395A |
probably benign |
Het |
| Tmc8 |
A |
G |
11: 117,683,550 (GRCm39) |
S702G |
probably benign |
Het |
| Tmem202 |
A |
G |
9: 59,426,477 (GRCm39) |
S230P |
possibly damaging |
Het |
| Tmem203 |
T |
C |
2: 25,145,764 (GRCm39) |
V28A |
probably benign |
Het |
| Traf3ip1 |
A |
T |
1: 91,455,479 (GRCm39) |
S647C |
probably damaging |
Het |
| Tram1 |
A |
T |
1: 13,659,870 (GRCm39) |
I26N |
probably damaging |
Het |
| Ttc6 |
A |
T |
12: 57,721,478 (GRCm39) |
D989V |
possibly damaging |
Het |
| Ttll6 |
A |
G |
11: 96,036,372 (GRCm39) |
T334A |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,750,086 (GRCm39) |
D3654E |
probably damaging |
Het |
| Ufd1 |
T |
G |
16: 18,639,832 (GRCm39) |
V112G |
probably damaging |
Het |
| Usp9y |
A |
T |
Y: 1,391,284 (GRCm39) |
Y629N |
possibly damaging |
Het |
| Vmn2r1 |
A |
G |
3: 63,989,267 (GRCm39) |
I69V |
probably benign |
Het |
| Zfp180 |
A |
T |
7: 23,805,246 (GRCm39) |
Y555F |
probably damaging |
Het |
| Zfp438 |
T |
C |
18: 5,214,403 (GRCm39) |
N185S |
probably benign |
Het |
| Zfp445 |
C |
T |
9: 122,686,215 (GRCm39) |
V15I |
possibly damaging |
Het |
| Zfp462 |
A |
G |
4: 55,013,476 (GRCm39) |
E1814G |
probably benign |
Het |
|
| Other mutations in Ercc6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00321:Ercc6
|
APN |
14 |
32,290,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00796:Ercc6
|
APN |
14 |
32,291,959 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00916:Ercc6
|
APN |
14 |
32,284,612 (GRCm39) |
intron |
probably benign |
|
|
IGL01743:Ercc6
|
APN |
14 |
32,274,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01802:Ercc6
|
APN |
14 |
32,284,531 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01886:Ercc6
|
APN |
14 |
32,291,537 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02100:Ercc6
|
APN |
14 |
32,239,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02115:Ercc6
|
APN |
14 |
32,298,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02755:Ercc6
|
APN |
14 |
32,297,705 (GRCm39) |
splice site |
probably benign |
|
|
IGL02964:Ercc6
|
APN |
14 |
32,292,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02998:Ercc6
|
APN |
14 |
32,279,814 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03150:Ercc6
|
APN |
14 |
32,280,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0152:Ercc6
|
UTSW |
14 |
32,268,862 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R0519:Ercc6
|
UTSW |
14 |
32,248,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0591:Ercc6
|
UTSW |
14 |
32,279,973 (GRCm39) |
splice site |
probably benign |
|
|
R0894:Ercc6
|
UTSW |
14 |
32,238,985 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0946:Ercc6
|
UTSW |
14 |
32,274,578 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1313:Ercc6
|
UTSW |
14 |
32,274,677 (GRCm39) |
splice site |
probably benign |
|
|
R1506:Ercc6
|
UTSW |
14 |
32,291,821 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1528:Ercc6
|
UTSW |
14 |
32,240,979 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1711:Ercc6
|
UTSW |
14 |
32,248,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1753:Ercc6
|
UTSW |
14 |
32,298,956 (GRCm39) |
missense |
probably benign |
|
|
R1795:Ercc6
|
UTSW |
14 |
32,238,985 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1843:Ercc6
|
UTSW |
14 |
32,268,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1853:Ercc6
|
UTSW |
14 |
32,298,773 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1859:Ercc6
|
UTSW |
14 |
32,248,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1912:Ercc6
|
UTSW |
14 |
32,298,760 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2308:Ercc6
|
UTSW |
14 |
32,288,366 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R2322:Ercc6
|
UTSW |
14 |
32,248,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2386:Ercc6
|
UTSW |
14 |
32,263,316 (GRCm39) |
splice site |
probably null |
|
|
R4170:Ercc6
|
UTSW |
14 |
32,288,754 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4369:Ercc6
|
UTSW |
14 |
32,239,164 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4389:Ercc6
|
UTSW |
14 |
32,296,865 (GRCm39) |
nonsense |
probably null |
|
|
R4811:Ercc6
|
UTSW |
14 |
32,296,886 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4840:Ercc6
|
UTSW |
14 |
32,263,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4973:Ercc6
|
UTSW |
14 |
32,296,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5068:Ercc6
|
UTSW |
14 |
32,292,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5069:Ercc6
|
UTSW |
14 |
32,292,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5070:Ercc6
|
UTSW |
14 |
32,292,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5093:Ercc6
|
UTSW |
14 |
32,289,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5265:Ercc6
|
UTSW |
14 |
32,291,580 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5272:Ercc6
|
UTSW |
14 |
32,240,985 (GRCm39) |
nonsense |
probably null |
|
|
R5499:Ercc6
|
UTSW |
14 |
32,238,916 (GRCm39) |
start codon destroyed |
probably null |
0.98 |
|
R5795:Ercc6
|
UTSW |
14 |
32,248,309 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6258:Ercc6
|
UTSW |
14 |
32,279,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6260:Ercc6
|
UTSW |
14 |
32,279,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6267:Ercc6
|
UTSW |
14 |
32,248,360 (GRCm39) |
nonsense |
probably null |
|
|
R6291:Ercc6
|
UTSW |
14 |
32,291,943 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6296:Ercc6
|
UTSW |
14 |
32,248,360 (GRCm39) |
nonsense |
probably null |
|
|
R6361:Ercc6
|
UTSW |
14 |
32,239,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6500:Ercc6
|
UTSW |
14 |
32,248,780 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6555:Ercc6
|
UTSW |
14 |
32,239,064 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6724:Ercc6
|
UTSW |
14 |
32,288,288 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6925:Ercc6
|
UTSW |
14 |
32,284,565 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7143:Ercc6
|
UTSW |
14 |
32,292,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7327:Ercc6
|
UTSW |
14 |
32,248,361 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7396:Ercc6
|
UTSW |
14 |
32,291,762 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7529:Ercc6
|
UTSW |
14 |
32,282,686 (GRCm39) |
nonsense |
probably null |
|
|
R7609:Ercc6
|
UTSW |
14 |
32,288,318 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7802:Ercc6
|
UTSW |
14 |
32,239,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7854:Ercc6
|
UTSW |
14 |
32,288,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Ercc6
|
UTSW |
14 |
32,284,526 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8181:Ercc6
|
UTSW |
14 |
32,279,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8320:Ercc6
|
UTSW |
14 |
32,242,972 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8388:Ercc6
|
UTSW |
14 |
32,292,297 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R8479:Ercc6
|
UTSW |
14 |
32,248,363 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8831:Ercc6
|
UTSW |
14 |
32,282,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8849:Ercc6
|
UTSW |
14 |
32,291,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8912:Ercc6
|
UTSW |
14 |
32,248,211 (GRCm39) |
missense |
probably benign |
0.40 |
|
R9210:Ercc6
|
UTSW |
14 |
32,291,822 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9309:Ercc6
|
UTSW |
14 |
32,240,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9499:Ercc6
|
UTSW |
14 |
32,284,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9552:Ercc6
|
UTSW |
14 |
32,284,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9562:Ercc6
|
UTSW |
14 |
32,296,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9688:Ercc6
|
UTSW |
14 |
32,297,755 (GRCm39) |
missense |
probably benign |
|
|
R9699:Ercc6
|
UTSW |
14 |
32,282,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9743:Ercc6
|
UTSW |
14 |
32,298,943 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Ercc6
|
UTSW |
14 |
32,248,444 (GRCm39) |
missense |
probably benign |
0.27 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTGTGTTCTCCCTATTACAG -3'
(R):5'- AAGAACCCTGCTTCTCACTGG -3'
Sequencing Primer
(F):5'- TTACAGGAACGGGCTCCAGTATTC -3'
(R):5'- GTGCTTGCCTCCACTGGTG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation