Incidental Mutation 'R4751:Abca14'
| ID |
357593 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca14
|
| Ensembl Gene |
ENSMUSG00000062017 |
| Gene Name |
ATP-binding cassette, sub-family A member 14 |
| Synonyms |
1700110B15Rik, 4930539G24Rik |
| MMRRC Submission |
041970-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4751 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
119803184-119924575 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 119911400 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1328
(E1328G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000081690
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000084640]
|
| AlphaFold |
E9Q8F8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000084640
AA Change: E1328G
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000081690
Gene: ENSMUSG00000062017
AA Change: E1328G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
24 |
463 |
5.7e-23 |
PFAM |
|
AAA
|
548 |
729 |
1.59e-10 |
SMART |
|
Pfam:ABC2_membrane_3
|
902 |
1296 |
1.2e-36 |
PFAM |
|
AAA
|
1384 |
1568 |
1.33e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.4%
|
| Validation Efficiency |
95% (124/131) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1)
|
| Other mutations in this stock |
Total: 115 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9130023H24Rik |
A |
T |
7: 127,836,258 (GRCm39) |
C112S |
probably benign |
Het |
| Abca13 |
G |
A |
11: 9,227,973 (GRCm39) |
|
probably null |
Het |
| Abca9 |
T |
A |
11: 110,021,396 (GRCm39) |
I1105F |
probably benign |
Het |
| Abr |
T |
C |
11: 76,347,434 (GRCm39) |
N396D |
possibly damaging |
Het |
| Aftph |
A |
C |
11: 20,677,074 (GRCm39) |
C178W |
probably damaging |
Het |
| Akr1c14 |
T |
C |
13: 4,115,338 (GRCm39) |
F89S |
possibly damaging |
Het |
| Ank3 |
C |
T |
10: 69,822,036 (GRCm39) |
A1518V |
probably benign |
Het |
| Arfgap2 |
T |
G |
2: 91,097,713 (GRCm39) |
S143R |
probably benign |
Het |
| Aspdh |
T |
A |
7: 44,116,629 (GRCm39) |
C107* |
probably null |
Het |
| Asphd2 |
C |
A |
5: 112,539,612 (GRCm39) |
G74W |
probably damaging |
Het |
| AU040320 |
G |
A |
4: 126,748,259 (GRCm39) |
|
probably null |
Het |
| B3glct |
T |
A |
5: 149,648,867 (GRCm39) |
|
probably null |
Het |
| Bcl9l |
A |
G |
9: 44,418,100 (GRCm39) |
K646R |
probably damaging |
Het |
| Brat1 |
T |
G |
5: 140,704,051 (GRCm39) |
L768R |
probably damaging |
Het |
| Btbd18 |
T |
A |
2: 84,498,265 (GRCm39) |
Y634* |
probably null |
Het |
| Bub1 |
T |
A |
2: 127,665,858 (GRCm39) |
|
probably benign |
Het |
| Carns1 |
A |
T |
19: 4,216,417 (GRCm39) |
D588E |
probably damaging |
Het |
| Cast |
T |
C |
13: 74,894,166 (GRCm39) |
K141E |
probably damaging |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,619,782 (GRCm39) |
|
probably benign |
Het |
| Chsy3 |
T |
C |
18: 59,308,872 (GRCm39) |
S42P |
possibly damaging |
Het |
| Clca3a1 |
A |
T |
3: 144,710,609 (GRCm39) |
F865I |
possibly damaging |
Het |
| Clec4f |
T |
A |
6: 83,622,264 (GRCm39) |
M526L |
possibly damaging |
Het |
| Clnk |
T |
C |
5: 38,878,256 (GRCm39) |
E301G |
probably benign |
Het |
| Colgalt2 |
T |
A |
1: 152,365,627 (GRCm39) |
I309N |
probably benign |
Het |
| Cyp2e1 |
A |
T |
7: 140,354,629 (GRCm39) |
K326* |
probably null |
Het |
| Dagla |
T |
A |
19: 10,227,758 (GRCm39) |
T717S |
probably benign |
Het |
| Dnajc11 |
G |
A |
4: 152,052,999 (GRCm39) |
R141H |
probably benign |
Het |
| Dst |
A |
G |
1: 34,230,965 (GRCm39) |
K2853E |
probably benign |
Het |
| Eif4g1 |
A |
G |
16: 20,505,265 (GRCm39) |
K1208E |
possibly damaging |
Het |
| Elane |
A |
G |
10: 79,722,625 (GRCm39) |
R48G |
probably benign |
Het |
| Fbxo30 |
T |
A |
10: 11,165,939 (GRCm39) |
N220K |
probably benign |
Het |
| Fbxo33 |
A |
T |
12: 59,247,714 (GRCm39) |
|
probably benign |
Het |
| Fetub |
G |
A |
16: 22,756,645 (GRCm39) |
V169I |
probably benign |
Het |
| Gpx6 |
A |
C |
13: 21,501,234 (GRCm39) |
Q107H |
probably damaging |
Het |
| H2bc18 |
A |
T |
3: 96,176,467 (GRCm39) |
|
probably benign |
Het |
| Homer3 |
A |
T |
8: 70,738,084 (GRCm39) |
I19F |
probably damaging |
Het |
| Hspa4 |
C |
T |
11: 53,175,026 (GRCm39) |
V144I |
probably benign |
Het |
| Icos |
C |
T |
1: 61,032,876 (GRCm39) |
S25L |
probably benign |
Het |
| Ifna4 |
A |
G |
4: 88,760,185 (GRCm39) |
T30A |
probably benign |
Het |
| Ino80b |
C |
T |
6: 83,101,731 (GRCm39) |
G46D |
probably damaging |
Het |
| Kpna2 |
T |
G |
11: 106,883,490 (GRCm39) |
I100L |
possibly damaging |
Het |
| Krt71 |
C |
T |
15: 101,643,901 (GRCm39) |
G446R |
probably damaging |
Het |
| Krtap31-2 |
A |
G |
11: 99,827,402 (GRCm39) |
N78S |
possibly damaging |
Het |
| Lman1 |
A |
G |
18: 66,131,505 (GRCm39) |
S132P |
probably benign |
Het |
| Lmna |
T |
C |
3: 88,393,840 (GRCm39) |
Q246R |
possibly damaging |
Het |
| Lrp10 |
T |
A |
14: 54,706,049 (GRCm39) |
V413E |
probably damaging |
Het |
| Macf1 |
A |
C |
4: 123,365,443 (GRCm39) |
I1541S |
probably benign |
Het |
| Med24 |
A |
G |
11: 98,597,258 (GRCm39) |
L874P |
probably damaging |
Het |
| Mgll |
T |
A |
6: 88,702,093 (GRCm39) |
|
probably benign |
Het |
| Mrpl37 |
A |
T |
4: 106,914,672 (GRCm39) |
L364Q |
probably damaging |
Het |
| Mrpl47 |
C |
T |
3: 32,782,590 (GRCm39) |
R209H |
probably benign |
Het |
| Muc5ac |
T |
C |
7: 141,371,338 (GRCm39) |
F3285L |
probably benign |
Het |
| Mylk |
A |
G |
16: 34,699,539 (GRCm39) |
R301G |
probably benign |
Het |
| Nacad |
A |
G |
11: 6,555,726 (GRCm39) |
L8P |
unknown |
Het |
| Ncf1 |
T |
A |
5: 134,258,399 (GRCm39) |
H8L |
probably damaging |
Het |
| Ncoa3 |
T |
A |
2: 165,911,823 (GRCm39) |
M1383K |
possibly damaging |
Het |
| Necab2 |
C |
T |
8: 120,194,337 (GRCm39) |
S271L |
probably benign |
Het |
| Nme8 |
A |
T |
13: 19,859,808 (GRCm39) |
|
probably null |
Het |
| Nsrp1 |
T |
G |
11: 76,967,545 (GRCm39) |
T16P |
possibly damaging |
Het |
| Obox3 |
A |
T |
7: 15,359,617 (GRCm39) |
|
probably null |
Het |
| Or1l8 |
T |
C |
2: 36,817,595 (GRCm39) |
H177R |
probably damaging |
Het |
| Or4c108 |
A |
G |
2: 88,803,477 (GRCm39) |
C253R |
probably damaging |
Het |
| Or4c15 |
T |
A |
2: 88,760,258 (GRCm39) |
I134F |
probably damaging |
Het |
| Or4d6 |
T |
A |
19: 12,086,541 (GRCm39) |
Y123F |
probably damaging |
Het |
| Or52n2b |
A |
T |
7: 104,565,617 (GRCm39) |
Y295* |
probably null |
Het |
| Or6b2 |
C |
A |
1: 92,407,705 (GRCm39) |
A213S |
probably benign |
Het |
| Osbpl3 |
C |
G |
6: 50,277,977 (GRCm39) |
E790Q |
possibly damaging |
Het |
| Osmr |
A |
T |
15: 6,872,333 (GRCm39) |
W254R |
probably damaging |
Het |
| Otoa |
T |
C |
7: 120,732,147 (GRCm39) |
|
probably benign |
Het |
| Pagr1a |
A |
T |
7: 126,614,551 (GRCm39) |
L218H |
probably damaging |
Het |
| Pcdha11 |
G |
A |
18: 37,139,997 (GRCm39) |
G542D |
probably damaging |
Het |
| Pck2 |
T |
A |
14: 55,780,018 (GRCm39) |
I54N |
probably damaging |
Het |
| Ppif |
T |
C |
14: 25,699,923 (GRCm39) |
V173A |
probably damaging |
Het |
| Ptgs2 |
T |
A |
1: 149,979,771 (GRCm39) |
L292H |
probably damaging |
Het |
| Ptpru |
A |
G |
4: 131,529,897 (GRCm39) |
S604P |
probably damaging |
Het |
| Qrfpr |
T |
C |
3: 36,236,771 (GRCm39) |
H210R |
possibly damaging |
Het |
| Rasgrf1 |
A |
G |
9: 89,792,171 (GRCm39) |
T41A |
probably damaging |
Het |
| Rasgrf1 |
A |
G |
9: 89,894,919 (GRCm39) |
H1113R |
probably damaging |
Het |
| Rhoc |
T |
A |
3: 104,699,963 (GRCm39) |
I80N |
probably damaging |
Het |
| Riok3 |
A |
G |
18: 12,287,040 (GRCm39) |
N472S |
probably benign |
Het |
| Rnf213 |
A |
G |
11: 119,336,571 (GRCm39) |
Y3314C |
probably benign |
Het |
| Shank2 |
C |
T |
7: 143,963,205 (GRCm39) |
T264I |
probably damaging |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Sipa1l1 |
A |
G |
12: 82,387,968 (GRCm39) |
I65V |
probably benign |
Het |
| Slc22a19 |
T |
C |
19: 7,668,510 (GRCm39) |
K291R |
possibly damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,030,488 (GRCm39) |
I315V |
probably benign |
Het |
| Slc44a1 |
A |
T |
4: 53,560,973 (GRCm39) |
D563V |
probably damaging |
Het |
| Smchd1 |
A |
T |
17: 71,698,463 (GRCm39) |
H1104Q |
probably benign |
Het |
| Spcs2 |
A |
T |
7: 99,493,976 (GRCm39) |
|
probably null |
Het |
| Speer1e |
T |
A |
5: 11,236,458 (GRCm39) |
Y138N |
probably damaging |
Het |
| Sptb |
T |
C |
12: 76,673,884 (GRCm39) |
E301G |
probably benign |
Het |
| Stum |
T |
C |
1: 180,270,234 (GRCm39) |
D86G |
probably damaging |
Het |
| Sufu |
A |
T |
19: 46,472,088 (GRCm39) |
D449V |
probably benign |
Het |
| Sun5 |
T |
C |
2: 153,707,936 (GRCm39) |
|
probably null |
Het |
| Tbc1d15 |
T |
A |
10: 115,038,492 (GRCm39) |
I574F |
probably damaging |
Het |
| Tert |
G |
A |
13: 73,776,182 (GRCm39) |
S311N |
possibly damaging |
Het |
| Tiparp |
T |
C |
3: 65,460,225 (GRCm39) |
Y507H |
probably damaging |
Het |
| Tnk2 |
T |
C |
16: 32,498,675 (GRCm39) |
C158R |
probably damaging |
Het |
| Tpgs1 |
T |
C |
10: 79,511,454 (GRCm39) |
S199P |
possibly damaging |
Het |
| Trdmt1 |
G |
T |
2: 13,549,464 (GRCm39) |
|
probably benign |
Het |
| Trp53bp1 |
T |
A |
2: 121,058,290 (GRCm39) |
D944V |
probably damaging |
Het |
| Tsc1 |
T |
A |
2: 28,569,093 (GRCm39) |
I720N |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,539,949 (GRCm39) |
T34346A |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,727,925 (GRCm39) |
|
probably benign |
Het |
| Uba7 |
T |
A |
9: 107,857,004 (GRCm39) |
C686S |
possibly damaging |
Het |
| Ush2a |
T |
A |
1: 188,582,284 (GRCm39) |
F3782L |
probably damaging |
Het |
| Vars2 |
A |
T |
17: 35,970,235 (GRCm39) |
H745Q |
possibly damaging |
Het |
| Vgf |
T |
A |
5: 137,061,255 (GRCm39) |
D472E |
probably damaging |
Het |
| Vmn2r15 |
T |
C |
5: 109,434,620 (GRCm39) |
M695V |
probably benign |
Het |
| Vps41 |
A |
T |
13: 18,995,792 (GRCm39) |
D208V |
probably damaging |
Het |
| Vta1 |
C |
T |
10: 14,531,560 (GRCm39) |
A272T |
probably benign |
Het |
| Wnk4 |
G |
A |
11: 101,167,188 (GRCm39) |
|
probably benign |
Het |
| Zfp507 |
T |
C |
7: 35,493,807 (GRCm39) |
K412R |
probably damaging |
Het |
| Zfp768 |
A |
G |
7: 126,943,934 (GRCm39) |
F65L |
possibly damaging |
Het |
| Zfp956 |
T |
C |
6: 47,940,510 (GRCm39) |
S290P |
probably benign |
Het |
|
| Other mutations in Abca14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00486:Abca14
|
APN |
7 |
119,846,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00800:Abca14
|
APN |
7 |
119,854,613 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00845:Abca14
|
APN |
7 |
119,823,174 (GRCm39) |
splice site |
probably benign |
|
|
IGL00897:Abca14
|
APN |
7 |
119,815,348 (GRCm39) |
splice site |
probably benign |
|
|
IGL01524:Abca14
|
APN |
7 |
119,852,644 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL01747:Abca14
|
APN |
7 |
119,877,310 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02214:Abca14
|
APN |
7 |
119,893,398 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02215:Abca14
|
APN |
7 |
119,852,612 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02253:Abca14
|
APN |
7 |
119,807,182 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02302:Abca14
|
APN |
7 |
119,917,968 (GRCm39) |
splice site |
probably benign |
|
|
IGL03391:Abca14
|
APN |
7 |
119,846,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F6893:Abca14
|
UTSW |
7 |
119,924,261 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0109:Abca14
|
UTSW |
7 |
119,917,985 (GRCm39) |
nonsense |
probably null |
|
|
R0109:Abca14
|
UTSW |
7 |
119,917,985 (GRCm39) |
nonsense |
probably null |
|
|
R0265:Abca14
|
UTSW |
7 |
119,822,850 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0326:Abca14
|
UTSW |
7 |
119,823,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Abca14
|
UTSW |
7 |
119,877,703 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0418:Abca14
|
UTSW |
7 |
119,806,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0539:Abca14
|
UTSW |
7 |
119,807,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0574:Abca14
|
UTSW |
7 |
119,823,720 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0611:Abca14
|
UTSW |
7 |
119,851,479 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R0783:Abca14
|
UTSW |
7 |
119,893,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0785:Abca14
|
UTSW |
7 |
119,893,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0863:Abca14
|
UTSW |
7 |
119,815,453 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1034:Abca14
|
UTSW |
7 |
119,815,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1056:Abca14
|
UTSW |
7 |
119,924,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1072:Abca14
|
UTSW |
7 |
119,811,992 (GRCm39) |
missense |
probably benign |
|
|
R1244:Abca14
|
UTSW |
7 |
119,815,561 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1255:Abca14
|
UTSW |
7 |
119,807,016 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1271:Abca14
|
UTSW |
7 |
119,924,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1325:Abca14
|
UTSW |
7 |
119,846,545 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1457:Abca14
|
UTSW |
7 |
119,888,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1467:Abca14
|
UTSW |
7 |
119,815,405 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1467:Abca14
|
UTSW |
7 |
119,815,405 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1494:Abca14
|
UTSW |
7 |
119,815,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1551:Abca14
|
UTSW |
7 |
119,918,101 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1607:Abca14
|
UTSW |
7 |
119,850,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1739:Abca14
|
UTSW |
7 |
119,877,529 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1856:Abca14
|
UTSW |
7 |
119,877,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Abca14
|
UTSW |
7 |
119,847,190 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1892:Abca14
|
UTSW |
7 |
119,815,561 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1898:Abca14
|
UTSW |
7 |
119,850,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1958:Abca14
|
UTSW |
7 |
119,924,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2018:Abca14
|
UTSW |
7 |
119,815,408 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2039:Abca14
|
UTSW |
7 |
119,911,487 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2060:Abca14
|
UTSW |
7 |
119,826,741 (GRCm39) |
nonsense |
probably null |
|
|
R2202:Abca14
|
UTSW |
7 |
119,888,764 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2205:Abca14
|
UTSW |
7 |
119,846,503 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2360:Abca14
|
UTSW |
7 |
119,850,431 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2401:Abca14
|
UTSW |
7 |
119,882,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2426:Abca14
|
UTSW |
7 |
119,882,446 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3433:Abca14
|
UTSW |
7 |
119,893,455 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4598:Abca14
|
UTSW |
7 |
119,854,626 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4599:Abca14
|
UTSW |
7 |
119,854,626 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4700:Abca14
|
UTSW |
7 |
119,911,928 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4826:Abca14
|
UTSW |
7 |
119,815,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4828:Abca14
|
UTSW |
7 |
119,815,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4837:Abca14
|
UTSW |
7 |
119,846,203 (GRCm39) |
missense |
probably benign |
|
|
R4881:Abca14
|
UTSW |
7 |
119,877,472 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4895:Abca14
|
UTSW |
7 |
119,846,572 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4928:Abca14
|
UTSW |
7 |
119,923,803 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4990:Abca14
|
UTSW |
7 |
119,911,388 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Abca14
|
UTSW |
7 |
119,911,505 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5091:Abca14
|
UTSW |
7 |
119,851,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5158:Abca14
|
UTSW |
7 |
119,852,652 (GRCm39) |
missense |
probably benign |
|
|
R5209:Abca14
|
UTSW |
7 |
119,832,130 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5333:Abca14
|
UTSW |
7 |
119,888,769 (GRCm39) |
nonsense |
probably null |
|
|
R5424:Abca14
|
UTSW |
7 |
119,810,777 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5488:Abca14
|
UTSW |
7 |
119,851,473 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5489:Abca14
|
UTSW |
7 |
119,851,473 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5716:Abca14
|
UTSW |
7 |
119,846,217 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6450:Abca14
|
UTSW |
7 |
119,815,449 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6477:Abca14
|
UTSW |
7 |
119,924,325 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6652:Abca14
|
UTSW |
7 |
119,846,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Abca14
|
UTSW |
7 |
119,847,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6874:Abca14
|
UTSW |
7 |
119,851,428 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6965:Abca14
|
UTSW |
7 |
119,882,452 (GRCm39) |
nonsense |
probably null |
|
|
R7142:Abca14
|
UTSW |
7 |
119,850,406 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7146:Abca14
|
UTSW |
7 |
119,854,520 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7202:Abca14
|
UTSW |
7 |
119,917,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7220:Abca14
|
UTSW |
7 |
119,826,667 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R7241:Abca14
|
UTSW |
7 |
119,846,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7291:Abca14
|
UTSW |
7 |
119,888,832 (GRCm39) |
nonsense |
probably null |
|
|
R7296:Abca14
|
UTSW |
7 |
119,877,534 (GRCm39) |
missense |
probably benign |
|
|
R7298:Abca14
|
UTSW |
7 |
119,807,106 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7315:Abca14
|
UTSW |
7 |
119,893,341 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7776:Abca14
|
UTSW |
7 |
119,832,214 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7820:Abca14
|
UTSW |
7 |
119,811,944 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7873:Abca14
|
UTSW |
7 |
119,888,792 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8215:Abca14
|
UTSW |
7 |
119,893,425 (GRCm39) |
missense |
probably benign |
|
|
R8332:Abca14
|
UTSW |
7 |
119,815,436 (GRCm39) |
missense |
probably benign |
|
|
R8419:Abca14
|
UTSW |
7 |
119,815,489 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8444:Abca14
|
UTSW |
7 |
119,918,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8818:Abca14
|
UTSW |
7 |
119,815,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8834:Abca14
|
UTSW |
7 |
119,877,372 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8845:Abca14
|
UTSW |
7 |
119,846,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8889:Abca14
|
UTSW |
7 |
119,815,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8892:Abca14
|
UTSW |
7 |
119,815,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8894:Abca14
|
UTSW |
7 |
119,847,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8903:Abca14
|
UTSW |
7 |
119,815,526 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8950:Abca14
|
UTSW |
7 |
119,823,595 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8950:Abca14
|
UTSW |
7 |
119,823,644 (GRCm39) |
nonsense |
probably null |
|
|
R9018:Abca14
|
UTSW |
7 |
119,918,532 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9018:Abca14
|
UTSW |
7 |
119,888,763 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9110:Abca14
|
UTSW |
7 |
119,831,615 (GRCm39) |
intron |
probably benign |
|
|
R9254:Abca14
|
UTSW |
7 |
119,807,202 (GRCm39) |
nonsense |
probably null |
|
|
R9376:Abca14
|
UTSW |
7 |
119,893,438 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9378:Abca14
|
UTSW |
7 |
119,807,191 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9379:Abca14
|
UTSW |
7 |
119,807,202 (GRCm39) |
nonsense |
probably null |
|
|
R9388:Abca14
|
UTSW |
7 |
119,882,261 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9445:Abca14
|
UTSW |
7 |
119,877,691 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9522:Abca14
|
UTSW |
7 |
119,847,368 (GRCm39) |
missense |
probably null |
0.98 |
|
R9577:Abca14
|
UTSW |
7 |
119,810,768 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9627:Abca14
|
UTSW |
7 |
119,854,530 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:Abca14
|
UTSW |
7 |
119,893,345 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Abca14
|
UTSW |
7 |
119,851,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9696:Abca14
|
UTSW |
7 |
119,888,734 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9709:Abca14
|
UTSW |
7 |
119,888,739 (GRCm39) |
nonsense |
probably null |
|
|
R9780:Abca14
|
UTSW |
7 |
119,911,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Abca14
|
UTSW |
7 |
119,815,358 (GRCm39) |
missense |
probably benign |
0.14 |
|
Z1176:Abca14
|
UTSW |
7 |
119,846,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Abca14
|
UTSW |
7 |
119,917,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCTGTGCAGACTAGTCTCG -3'
(R):5'- CATGAGCTATCAGGACTTATCTTAGG -3'
Sequencing Primer
(F):5'- TCCTGGAACCAAGATGGCTC -3'
(R):5'- TCTTAGGGAATGAAGCCATATGC -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation