Incidental Mutation 'R4755:Thsd7b'
| ID |
357867 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thsd7b
|
| Ensembl Gene |
ENSMUSG00000042581 |
| Gene Name |
thrombospondin, type I, domain containing 7B |
| Synonyms |
1700074E13Rik, D130067I03Rik |
| MMRRC Submission |
042033-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.092)
|
| Stock # |
R4755 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
129201039-130147015 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 130138001 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 1560
(Y1560N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073220
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000073527]
|
| AlphaFold |
Q6P4U0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000073527
AA Change: Y1560N
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000073220
Gene: ENSMUSG00000042581
AA Change: Y1560N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
36 |
N/A |
INTRINSIC |
|
Blast:TSP1
|
43 |
98 |
5e-29 |
BLAST |
|
Blast:TSP1
|
122 |
177 |
9e-24 |
BLAST |
|
TSP1
|
182 |
233 |
2.47e-9 |
SMART |
|
TSP1
|
339 |
399 |
7e-9 |
SMART |
|
Blast:TSP1
|
402 |
482 |
2e-27 |
BLAST |
|
TSP1
|
487 |
543 |
2.12e-1 |
SMART |
|
TSP1
|
604 |
661 |
3.9e-7 |
SMART |
|
TSP1
|
664 |
735 |
2.73e-2 |
SMART |
|
TSP1
|
740 |
796 |
1.01e-5 |
SMART |
|
Blast:TSP1
|
799 |
869 |
6e-35 |
BLAST |
|
TSP1
|
874 |
922 |
9.68e-3 |
SMART |
|
TSP1
|
952 |
999 |
2.42e0 |
SMART |
|
TSP1
|
1004 |
1059 |
3.96e-8 |
SMART |
|
TSP1
|
1062 |
1126 |
1.73e0 |
SMART |
|
TSP1
|
1131 |
1182 |
6.05e-4 |
SMART |
|
TSP1
|
1185 |
1246 |
9.52e-1 |
SMART |
|
TSP1
|
1251 |
1303 |
3.21e-8 |
SMART |
|
TSP1
|
1304 |
1369 |
5.52e-1 |
SMART |
|
TSP1
|
1374 |
1432 |
3.92e-2 |
SMART |
|
transmembrane domain
|
1558 |
1580 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140834
|
| Meta Mutation Damage Score |
0.3964 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
96% (112/117) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930449A18Rik |
T |
A |
3: 59,733,280 (GRCm39) |
|
noncoding transcript |
Het |
| Aadacl2fm1 |
C |
T |
3: 59,843,735 (GRCm39) |
A143V |
probably benign |
Het |
| Accs |
T |
C |
2: 93,671,682 (GRCm39) |
E236G |
probably damaging |
Het |
| Agrn |
C |
T |
4: 156,257,979 (GRCm39) |
|
probably benign |
Het |
| Ahi1 |
A |
G |
10: 20,930,946 (GRCm39) |
I929V |
possibly damaging |
Het |
| Akap5 |
C |
A |
12: 76,374,581 (GRCm39) |
C4* |
probably null |
Het |
| Amotl2 |
A |
T |
9: 102,597,679 (GRCm39) |
H146L |
probably damaging |
Het |
| Ank1 |
A |
G |
8: 23,594,990 (GRCm39) |
N666S |
probably damaging |
Het |
| Atp10d |
A |
T |
5: 72,403,509 (GRCm39) |
T373S |
probably benign |
Het |
| Bpifb9b |
T |
A |
2: 154,161,614 (GRCm39) |
M582K |
probably benign |
Het |
| Brca2 |
T |
A |
5: 150,483,452 (GRCm39) |
|
probably null |
Het |
| Ccdc149 |
A |
G |
5: 52,561,493 (GRCm39) |
V229A |
probably damaging |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,619,782 (GRCm39) |
|
probably benign |
Het |
| Cdk5rap2 |
A |
G |
4: 70,156,662 (GRCm39) |
S1617P |
probably damaging |
Het |
| Cenpk |
A |
T |
13: 104,367,379 (GRCm39) |
M37L |
probably benign |
Het |
| Cenpk |
A |
T |
13: 104,386,020 (GRCm39) |
H305L |
probably benign |
Het |
| Ces5a |
C |
A |
8: 94,262,305 (GRCm39) |
A11S |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,967,520 (GRCm39) |
E186G |
probably damaging |
Het |
| Cfh |
T |
A |
1: 140,016,546 (GRCm39) |
I593F |
probably damaging |
Het |
| Clstn2 |
C |
T |
9: 97,327,726 (GRCm39) |
V961I |
probably benign |
Het |
| Cog5 |
T |
A |
12: 31,919,405 (GRCm39) |
|
probably null |
Het |
| Col4a4 |
T |
C |
1: 82,518,895 (GRCm39) |
D100G |
unknown |
Het |
| Cyp3a41a |
T |
C |
5: 145,652,316 (GRCm39) |
D61G |
probably damaging |
Het |
| Dnah10 |
A |
G |
5: 124,824,809 (GRCm39) |
N655S |
probably benign |
Het |
| Dnai1 |
C |
G |
4: 41,610,269 (GRCm39) |
T295R |
probably damaging |
Het |
| Dnajc6 |
C |
T |
4: 101,407,996 (GRCm39) |
A44V |
probably damaging |
Het |
| Eif4enif1 |
A |
T |
11: 3,194,016 (GRCm39) |
D960V |
probably damaging |
Het |
| Fam167b |
C |
T |
4: 129,472,135 (GRCm39) |
G12R |
probably damaging |
Het |
| Fam20b |
A |
T |
1: 156,515,066 (GRCm39) |
Y266* |
probably null |
Het |
| Fer1l6 |
T |
A |
15: 58,512,060 (GRCm39) |
V1509D |
probably benign |
Het |
| Fhad1 |
A |
T |
4: 141,655,794 (GRCm39) |
I105N |
probably damaging |
Het |
| Fmo2 |
T |
C |
1: 162,716,374 (GRCm39) |
D71G |
probably damaging |
Het |
| Folr2 |
T |
C |
7: 101,493,006 (GRCm39) |
T6A |
possibly damaging |
Het |
| Fry |
A |
C |
5: 150,321,719 (GRCm39) |
E1018A |
probably damaging |
Het |
| Gas2l2 |
A |
G |
11: 83,320,193 (GRCm39) |
I21T |
probably damaging |
Het |
| Gfra1 |
T |
C |
19: 58,441,676 (GRCm39) |
Y85C |
probably damaging |
Het |
| Gpld1 |
A |
T |
13: 25,163,671 (GRCm39) |
Y43F |
probably benign |
Het |
| Gpld1 |
T |
A |
13: 25,163,675 (GRCm39) |
Y44* |
probably null |
Het |
| Grid2 |
A |
G |
6: 63,885,972 (GRCm39) |
T123A |
probably benign |
Het |
| Grina |
T |
C |
15: 76,133,442 (GRCm39) |
L305P |
probably damaging |
Het |
| Gucy1a1 |
G |
A |
3: 82,002,102 (GRCm39) |
A659V |
probably benign |
Het |
| H2-T10 |
T |
A |
17: 36,429,837 (GRCm39) |
K319* |
probably null |
Het |
| Hey2 |
A |
T |
10: 30,710,300 (GRCm39) |
V151E |
probably benign |
Het |
| Ighv1-69 |
G |
A |
12: 115,587,178 (GRCm39) |
T13I |
probably benign |
Het |
| Il1rap |
C |
A |
16: 26,541,532 (GRCm39) |
A591E |
probably benign |
Het |
| Ildr1 |
T |
C |
16: 36,542,383 (GRCm39) |
L261P |
probably benign |
Het |
| Jak1 |
A |
G |
4: 101,031,354 (GRCm39) |
Y463H |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 41,159,285 (GRCm39) |
I1666V |
probably benign |
Het |
| Lrp1b |
T |
A |
2: 41,361,028 (GRCm39) |
T592S |
probably benign |
Het |
| Lrrc36 |
A |
G |
8: 106,178,776 (GRCm39) |
T445A |
possibly damaging |
Het |
| Ly9 |
G |
A |
1: 171,434,806 (GRCm39) |
S29F |
probably damaging |
Het |
| Mapk7 |
A |
C |
11: 61,381,669 (GRCm39) |
C32W |
probably damaging |
Het |
| Marchf10 |
C |
T |
11: 105,255,302 (GRCm39) |
|
probably benign |
Het |
| Mier2 |
A |
T |
10: 79,385,031 (GRCm39) |
M119K |
probably damaging |
Het |
| Mpv17 |
A |
T |
5: 31,303,326 (GRCm39) |
C59* |
probably null |
Het |
| Mrpl27 |
G |
A |
11: 94,544,659 (GRCm39) |
|
probably benign |
Het |
| Myo18b |
G |
A |
5: 113,022,340 (GRCm39) |
Q351* |
probably null |
Het |
| Myo1a |
A |
G |
10: 127,551,557 (GRCm39) |
I704M |
probably damaging |
Het |
| Nadsyn1 |
A |
G |
7: 143,360,650 (GRCm39) |
C373R |
probably damaging |
Het |
| Nckipsd |
C |
A |
9: 108,691,938 (GRCm39) |
A513E |
probably benign |
Het |
| Neb |
T |
C |
2: 52,110,221 (GRCm39) |
D209G |
probably damaging |
Het |
| Nkapl |
T |
A |
13: 21,652,457 (GRCm39) |
Q52L |
unknown |
Het |
| Nptx2 |
G |
A |
5: 144,483,250 (GRCm39) |
S126N |
probably benign |
Het |
| Or2a7 |
G |
A |
6: 43,150,977 (GRCm39) |
S19N |
probably benign |
Het |
| Or52d3 |
T |
A |
7: 104,229,268 (GRCm39) |
Y138* |
probably null |
Het |
| Or7g17 |
A |
T |
9: 18,768,476 (GRCm39) |
H185L |
probably benign |
Het |
| Or8b52 |
A |
G |
9: 38,577,128 (GRCm39) |
V4A |
probably benign |
Het |
| Pclo |
A |
T |
5: 14,764,362 (GRCm39) |
R4278S |
unknown |
Het |
| Pcnx1 |
T |
G |
12: 81,997,068 (GRCm39) |
L988R |
probably damaging |
Het |
| Prl2c5 |
C |
A |
13: 13,363,970 (GRCm39) |
N75K |
probably benign |
Het |
| Prpf19 |
T |
G |
19: 10,875,154 (GRCm39) |
|
probably benign |
Het |
| Ralgapa1 |
A |
G |
12: 55,759,533 (GRCm39) |
S997P |
probably damaging |
Het |
| Rangap1 |
T |
C |
15: 81,597,118 (GRCm39) |
T226A |
probably benign |
Het |
| Rimklb |
G |
A |
6: 122,433,365 (GRCm39) |
L262F |
probably damaging |
Het |
| Rnf169 |
A |
G |
7: 99,574,930 (GRCm39) |
M555T |
probably benign |
Het |
| Rp1l1 |
A |
T |
14: 64,267,519 (GRCm39) |
D1035V |
probably benign |
Het |
| Rps23rg1 |
A |
T |
8: 3,633,922 (GRCm39) |
S8C |
probably damaging |
Het |
| Scd2 |
T |
A |
19: 44,289,791 (GRCm39) |
L262Q |
probably damaging |
Het |
| Scgb2b12 |
T |
A |
7: 32,024,956 (GRCm39) |
M84L |
probably benign |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Sipa1l1 |
G |
A |
12: 82,419,160 (GRCm39) |
V613I |
possibly damaging |
Het |
| Slc25a23 |
T |
A |
17: 57,359,794 (GRCm39) |
D67V |
possibly damaging |
Het |
| Slc25a39 |
C |
T |
11: 102,297,492 (GRCm39) |
|
probably benign |
Het |
| Slc4a10 |
T |
A |
2: 62,127,332 (GRCm39) |
F895Y |
probably damaging |
Het |
| Slc5a4a |
A |
C |
10: 76,022,398 (GRCm39) |
K578Q |
probably benign |
Het |
| Slc6a13 |
G |
A |
6: 121,302,008 (GRCm39) |
G197S |
probably damaging |
Het |
| Smarca2 |
A |
T |
19: 26,631,883 (GRCm39) |
E566V |
possibly damaging |
Het |
| Sorbs3 |
A |
T |
14: 70,421,548 (GRCm39) |
N594K |
probably benign |
Het |
| Spata22 |
A |
T |
11: 73,236,582 (GRCm39) |
D296V |
probably damaging |
Het |
| Sphk2 |
G |
A |
7: 45,363,058 (GRCm39) |
A11V |
possibly damaging |
Het |
| Spp1 |
A |
T |
5: 104,583,081 (GRCm39) |
|
probably benign |
Het |
| Strn3 |
T |
A |
12: 51,656,999 (GRCm39) |
I760L |
possibly damaging |
Het |
| Syk |
A |
T |
13: 52,796,022 (GRCm39) |
Y539F |
probably benign |
Het |
| Tdpoz9-ps1 |
T |
C |
3: 93,846,093 (GRCm39) |
|
probably null |
Het |
| Tmod2 |
C |
A |
9: 75,504,494 (GRCm39) |
E42* |
probably null |
Het |
| Tom1l1 |
T |
C |
11: 90,575,942 (GRCm39) |
E30G |
probably damaging |
Het |
| Trav10 |
G |
A |
14: 53,743,518 (GRCm39) |
A40T |
probably benign |
Het |
| Trav14-2 |
G |
A |
14: 53,878,237 (GRCm39) |
|
probably benign |
Het |
| Tril |
T |
A |
6: 53,795,449 (GRCm39) |
E591V |
probably damaging |
Het |
| Trp53bp1 |
T |
A |
2: 121,059,087 (GRCm39) |
R179* |
probably null |
Het |
| Tspoap1 |
A |
T |
11: 87,662,489 (GRCm39) |
D562V |
possibly damaging |
Het |
| Usp44 |
A |
T |
10: 93,682,768 (GRCm39) |
H406L |
probably damaging |
Het |
| Vangl1 |
A |
G |
3: 102,065,608 (GRCm39) |
I509T |
probably benign |
Het |
| Vax2 |
T |
G |
6: 83,688,379 (GRCm39) |
L34W |
probably damaging |
Het |
| Vmn1r55 |
A |
T |
7: 5,150,025 (GRCm39) |
C133S |
probably damaging |
Het |
| Vmn2r8 |
T |
A |
5: 108,949,566 (GRCm39) |
D427V |
probably benign |
Het |
| Vwde |
A |
G |
6: 13,205,851 (GRCm39) |
I232T |
possibly damaging |
Het |
| Wnk1 |
C |
A |
6: 119,940,431 (GRCm39) |
A769S |
probably damaging |
Het |
| Xpo4 |
A |
C |
14: 57,855,638 (GRCm39) |
S264A |
probably benign |
Het |
| Zfp330 |
A |
T |
8: 83,496,015 (GRCm39) |
C75* |
probably null |
Het |
| Zfp526 |
T |
A |
7: 24,925,064 (GRCm39) |
L441Q |
probably benign |
Het |
| Zfp607b |
T |
G |
7: 27,402,930 (GRCm39) |
L462R |
probably damaging |
Het |
| Zfp719 |
T |
A |
7: 43,240,217 (GRCm39) |
F602I |
probably damaging |
Het |
|
| Other mutations in Thsd7b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00417:Thsd7b
|
APN |
1 |
129,523,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00850:Thsd7b
|
APN |
1 |
130,092,814 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00987:Thsd7b
|
APN |
1 |
129,541,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01068:Thsd7b
|
APN |
1 |
129,523,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01091:Thsd7b
|
APN |
1 |
129,704,071 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL01535:Thsd7b
|
APN |
1 |
129,605,954 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01560:Thsd7b
|
APN |
1 |
130,145,918 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01701:Thsd7b
|
APN |
1 |
129,358,665 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL01775:Thsd7b
|
APN |
1 |
129,556,676 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02077:Thsd7b
|
APN |
1 |
129,744,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02338:Thsd7b
|
APN |
1 |
129,523,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02340:Thsd7b
|
APN |
1 |
130,087,369 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02404:Thsd7b
|
APN |
1 |
129,540,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02519:Thsd7b
|
APN |
1 |
129,540,932 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02543:Thsd7b
|
APN |
1 |
130,092,840 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02740:Thsd7b
|
APN |
1 |
129,540,864 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02793:Thsd7b
|
APN |
1 |
129,879,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02875:Thsd7b
|
APN |
1 |
129,879,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02986:Thsd7b
|
APN |
1 |
129,843,352 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03108:Thsd7b
|
APN |
1 |
130,138,013 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03114:Thsd7b
|
APN |
1 |
130,116,288 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03195:Thsd7b
|
APN |
1 |
129,556,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03291:Thsd7b
|
APN |
1 |
129,688,092 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03397:Thsd7b
|
APN |
1 |
129,523,901 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL03399:Thsd7b
|
APN |
1 |
129,556,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0184:Thsd7b
|
UTSW |
1 |
129,358,701 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0277:Thsd7b
|
UTSW |
1 |
130,123,000 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0526:Thsd7b
|
UTSW |
1 |
129,879,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0633:Thsd7b
|
UTSW |
1 |
130,116,263 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0746:Thsd7b
|
UTSW |
1 |
130,116,268 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0784:Thsd7b
|
UTSW |
1 |
129,523,096 (GRCm39) |
splice site |
probably benign |
|
|
R1158:Thsd7b
|
UTSW |
1 |
130,117,672 (GRCm39) |
splice site |
probably null |
|
|
R1267:Thsd7b
|
UTSW |
1 |
129,556,577 (GRCm39) |
splice site |
probably null |
|
|
R1375:Thsd7b
|
UTSW |
1 |
130,087,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Thsd7b
|
UTSW |
1 |
129,523,778 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1728:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1728:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1728:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1729:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1729:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1729:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1729:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1730:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1730:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1730:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1730:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1739:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1739:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1739:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1739:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1762:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1762:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1762:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1762:Thsd7b
|
UTSW |
1 |
130,030,813 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1762:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1783:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1783:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1783:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1783:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1784:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1784:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1784:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1784:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1785:Thsd7b
|
UTSW |
1 |
129,605,920 (GRCm39) |
missense |
probably benign |
|
|
R1785:Thsd7b
|
UTSW |
1 |
129,595,674 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1785:Thsd7b
|
UTSW |
1 |
129,556,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1785:Thsd7b
|
UTSW |
1 |
130,044,368 (GRCm39) |
missense |
probably benign |
|
|
R1812:Thsd7b
|
UTSW |
1 |
129,686,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1846:Thsd7b
|
UTSW |
1 |
129,540,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1908:Thsd7b
|
UTSW |
1 |
129,605,846 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1996:Thsd7b
|
UTSW |
1 |
129,686,188 (GRCm39) |
nonsense |
probably null |
|
|
R2199:Thsd7b
|
UTSW |
1 |
130,145,895 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2483:Thsd7b
|
UTSW |
1 |
130,030,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2919:Thsd7b
|
UTSW |
1 |
130,117,587 (GRCm39) |
splice site |
probably benign |
|
|
R2935:Thsd7b
|
UTSW |
1 |
129,605,824 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3113:Thsd7b
|
UTSW |
1 |
129,977,599 (GRCm39) |
missense |
probably benign |
0.23 |
|
R3236:Thsd7b
|
UTSW |
1 |
130,145,855 (GRCm39) |
nonsense |
probably null |
|
|
R3745:Thsd7b
|
UTSW |
1 |
129,605,978 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3877:Thsd7b
|
UTSW |
1 |
130,117,919 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3880:Thsd7b
|
UTSW |
1 |
129,523,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4110:Thsd7b
|
UTSW |
1 |
130,044,356 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4112:Thsd7b
|
UTSW |
1 |
130,044,356 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4255:Thsd7b
|
UTSW |
1 |
129,688,024 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4621:Thsd7b
|
UTSW |
1 |
129,358,652 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4703:Thsd7b
|
UTSW |
1 |
129,977,646 (GRCm39) |
intron |
probably benign |
|
|
R4732:Thsd7b
|
UTSW |
1 |
129,540,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Thsd7b
|
UTSW |
1 |
129,540,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4805:Thsd7b
|
UTSW |
1 |
130,116,276 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4840:Thsd7b
|
UTSW |
1 |
129,523,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4879:Thsd7b
|
UTSW |
1 |
130,116,236 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R4936:Thsd7b
|
UTSW |
1 |
129,605,882 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4972:Thsd7b
|
UTSW |
1 |
130,116,309 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5304:Thsd7b
|
UTSW |
1 |
129,605,980 (GRCm39) |
nonsense |
probably null |
|
|
R5422:Thsd7b
|
UTSW |
1 |
129,849,071 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5495:Thsd7b
|
UTSW |
1 |
129,523,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5598:Thsd7b
|
UTSW |
1 |
129,523,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5620:Thsd7b
|
UTSW |
1 |
130,090,673 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5638:Thsd7b
|
UTSW |
1 |
129,523,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5640:Thsd7b
|
UTSW |
1 |
130,044,408 (GRCm39) |
nonsense |
probably null |
|
|
R5655:Thsd7b
|
UTSW |
1 |
129,556,671 (GRCm39) |
splice site |
probably null |
|
|
R5711:Thsd7b
|
UTSW |
1 |
129,688,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5823:Thsd7b
|
UTSW |
1 |
129,605,821 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5888:Thsd7b
|
UTSW |
1 |
130,138,057 (GRCm39) |
nonsense |
probably null |
|
|
R5932:Thsd7b
|
UTSW |
1 |
129,358,575 (GRCm39) |
missense |
probably benign |
|
|
R6243:Thsd7b
|
UTSW |
1 |
130,090,599 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6258:Thsd7b
|
UTSW |
1 |
129,595,655 (GRCm39) |
missense |
probably benign |
|
|
R6260:Thsd7b
|
UTSW |
1 |
129,595,655 (GRCm39) |
missense |
probably benign |
|
|
R6399:Thsd7b
|
UTSW |
1 |
129,744,385 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6437:Thsd7b
|
UTSW |
1 |
129,744,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6719:Thsd7b
|
UTSW |
1 |
130,087,451 (GRCm39) |
splice site |
probably null |
|
|
R6785:Thsd7b
|
UTSW |
1 |
129,358,644 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7304:Thsd7b
|
UTSW |
1 |
130,030,890 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7334:Thsd7b
|
UTSW |
1 |
130,123,012 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7414:Thsd7b
|
UTSW |
1 |
129,556,717 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7673:Thsd7b
|
UTSW |
1 |
129,843,487 (GRCm39) |
splice site |
probably null |
|
|
R7683:Thsd7b
|
UTSW |
1 |
129,523,683 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7861:Thsd7b
|
UTSW |
1 |
130,087,435 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8145:Thsd7b
|
UTSW |
1 |
129,688,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8241:Thsd7b
|
UTSW |
1 |
130,117,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8296:Thsd7b
|
UTSW |
1 |
129,523,193 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8355:Thsd7b
|
UTSW |
1 |
129,523,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8507:Thsd7b
|
UTSW |
1 |
129,605,790 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8520:Thsd7b
|
UTSW |
1 |
129,849,157 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8555:Thsd7b
|
UTSW |
1 |
129,523,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8682:Thsd7b
|
UTSW |
1 |
129,688,011 (GRCm39) |
nonsense |
probably null |
|
|
R8981:Thsd7b
|
UTSW |
1 |
129,523,187 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9029:Thsd7b
|
UTSW |
1 |
130,087,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9133:Thsd7b
|
UTSW |
1 |
129,843,382 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9194:Thsd7b
|
UTSW |
1 |
129,843,371 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9229:Thsd7b
|
UTSW |
1 |
129,849,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9239:Thsd7b
|
UTSW |
1 |
130,087,453 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9460:Thsd7b
|
UTSW |
1 |
130,090,674 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9466:Thsd7b
|
UTSW |
1 |
130,122,866 (GRCm39) |
missense |
probably benign |
|
|
R9588:Thsd7b
|
UTSW |
1 |
130,108,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Thsd7b
|
UTSW |
1 |
129,523,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Thsd7b
|
UTSW |
1 |
129,556,648 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thsd7b
|
UTSW |
1 |
129,523,397 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Thsd7b
|
UTSW |
1 |
129,523,253 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Thsd7b
|
UTSW |
1 |
130,108,161 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCATTGAGTAATCGGCTAGC -3'
(R):5'- CTTAGTGGTCTGGAGATCCCTC -3'
Sequencing Primer
(F):5'- AGCTTAGGCATCCATTTCAGG -3'
(R):5'- CAGGGCCTATGTGATTTC -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation