Incidental Mutation 'R4740:St18'
| ID |
359573 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St18
|
| Ensembl Gene |
ENSMUSG00000033740 |
| Gene Name |
suppression of tumorigenicity 18 |
| Synonyms |
Nzf3, Myt3 |
| MMRRC Submission |
041965-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4740 (G1)
|
| Quality Score |
85 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
6557455-6931164 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to C
at 6887828 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Leucine
at position 466
(V466L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131417
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043578]
[ENSMUST00000131494]
[ENSMUST00000140079]
[ENSMUST00000150761]
[ENSMUST00000151281]
[ENSMUST00000163727]
|
| AlphaFold |
Q80TY4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043578
AA Change: V466L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000042056
Gene: ENSMUSG00000033740
AA Change: V466L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131494
AA Change: V466L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000117789
Gene: ENSMUSG00000033740
AA Change: V466L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140079
AA Change: V466L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000118322
Gene: ENSMUSG00000033740
AA Change: V466L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142304
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150761
AA Change: V466L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000120298
Gene: ENSMUSG00000033740
AA Change: V466L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151281
AA Change: V466L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000122055
Gene: ENSMUSG00000033740
AA Change: V466L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163727
AA Change: V466L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000131417
Gene: ENSMUSG00000033740
AA Change: V466L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.8%
|
| Validation Efficiency |
100% (95/95) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510009E07Rik |
C |
T |
16: 21,513,146 (GRCm39) |
A4T |
probably benign |
Het |
| Aacs |
T |
C |
5: 125,583,316 (GRCm39) |
S291P |
probably damaging |
Het |
| Abcb1a |
T |
C |
5: 8,752,280 (GRCm39) |
|
probably null |
Het |
| Apol10a |
C |
T |
15: 77,372,841 (GRCm39) |
T159I |
possibly damaging |
Het |
| Arhgap5 |
A |
T |
12: 52,565,860 (GRCm39) |
M944L |
probably benign |
Het |
| Atg16l2 |
A |
G |
7: 100,946,385 (GRCm39) |
L129P |
probably damaging |
Het |
| Baiap2l2 |
T |
A |
15: 79,143,951 (GRCm39) |
Y381F |
probably benign |
Het |
| Chd6 |
A |
T |
2: 160,812,103 (GRCm39) |
D1363E |
probably benign |
Het |
| Ciao3 |
A |
T |
17: 26,000,283 (GRCm39) |
H322L |
probably damaging |
Het |
| Cir1 |
T |
C |
2: 73,142,867 (GRCm39) |
|
probably benign |
Het |
| Clec4a2 |
T |
C |
6: 123,117,622 (GRCm39) |
I180T |
probably damaging |
Het |
| Clec4d |
T |
A |
6: 123,245,072 (GRCm39) |
H117Q |
probably damaging |
Het |
| Cntnap2 |
A |
T |
6: 45,037,251 (GRCm39) |
R10W |
possibly damaging |
Het |
| Coro6 |
A |
G |
11: 77,360,025 (GRCm39) |
E362G |
possibly damaging |
Het |
| Ctr9 |
T |
A |
7: 110,634,578 (GRCm39) |
C196S |
probably benign |
Het |
| Cyp2c55 |
A |
G |
19: 39,007,173 (GRCm39) |
K190E |
probably benign |
Het |
| Dbt |
T |
C |
3: 116,332,781 (GRCm39) |
I200T |
probably damaging |
Het |
| Dnah11 |
A |
G |
12: 118,084,279 (GRCm39) |
F1242L |
probably benign |
Het |
| Dnah2 |
A |
G |
11: 69,348,868 (GRCm39) |
W2534R |
probably damaging |
Het |
| Dph7 |
T |
C |
2: 24,853,143 (GRCm39) |
S86P |
possibly damaging |
Het |
| Dpp9 |
A |
C |
17: 56,505,970 (GRCm39) |
|
probably null |
Het |
| Eif4g3 |
T |
A |
4: 137,925,408 (GRCm39) |
S1584T |
probably benign |
Het |
| Eml4 |
T |
G |
17: 83,717,459 (GRCm39) |
D10E |
probably damaging |
Het |
| Enpp1 |
A |
T |
10: 24,555,146 (GRCm39) |
C67S |
probably null |
Het |
| Epn1 |
A |
G |
7: 5,093,012 (GRCm39) |
D108G |
probably damaging |
Het |
| Eps15 |
A |
G |
4: 109,200,387 (GRCm39) |
Y2C |
probably damaging |
Het |
| Fam135b |
C |
T |
15: 71,335,920 (GRCm39) |
V425I |
probably benign |
Het |
| Frem2 |
G |
A |
3: 53,443,240 (GRCm39) |
A2508V |
probably benign |
Het |
| Fzd3 |
T |
A |
14: 65,473,193 (GRCm39) |
M192L |
possibly damaging |
Het |
| Gls |
C |
T |
1: 52,271,947 (GRCm39) |
A69T |
probably damaging |
Het |
| Gm10051 |
T |
A |
5: 133,504,113 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9271 |
A |
G |
7: 39,013,346 (GRCm39) |
|
noncoding transcript |
Het |
| Gramd1b |
T |
C |
9: 40,227,128 (GRCm39) |
|
probably null |
Het |
| Gvin-ps6 |
G |
A |
7: 106,022,782 (GRCm39) |
|
noncoding transcript |
Het |
| H2-T23 |
A |
T |
17: 36,343,016 (GRCm39) |
|
probably benign |
Het |
| H2-T5 |
T |
A |
17: 36,478,448 (GRCm39) |
I195F |
probably damaging |
Het |
| Hmbox1 |
G |
A |
14: 65,134,483 (GRCm39) |
T39I |
probably damaging |
Het |
| Hmx1 |
A |
G |
5: 35,549,115 (GRCm39) |
E136G |
probably damaging |
Het |
| Hpdl |
T |
C |
4: 116,678,221 (GRCm39) |
N80S |
probably damaging |
Het |
| Hydin |
A |
G |
8: 111,173,071 (GRCm39) |
N918S |
probably benign |
Het |
| Igkv5-37 |
T |
A |
6: 69,940,306 (GRCm39) |
S113C |
probably damaging |
Het |
| Il36rn |
T |
C |
2: 24,167,503 (GRCm39) |
|
probably benign |
Het |
| Mab21l4 |
A |
C |
1: 93,083,890 (GRCm39) |
M189R |
probably benign |
Het |
| Marco |
G |
T |
1: 120,422,499 (GRCm39) |
T61K |
probably damaging |
Het |
| Med1 |
T |
A |
11: 98,071,090 (GRCm39) |
R86* |
probably null |
Het |
| Mertk |
A |
G |
2: 128,593,914 (GRCm39) |
Y306C |
probably damaging |
Het |
| Mgat4c |
T |
C |
10: 102,224,265 (GRCm39) |
F160L |
probably damaging |
Het |
| Midn |
A |
T |
10: 79,987,238 (GRCm39) |
E88V |
probably null |
Het |
| Muc4 |
G |
A |
16: 32,596,277 (GRCm39) |
R3163H |
possibly damaging |
Het |
| Naip1 |
T |
C |
13: 100,581,034 (GRCm39) |
D71G |
possibly damaging |
Het |
| Nhlrc4 |
T |
C |
17: 26,162,577 (GRCm39) |
T57A |
probably benign |
Het |
| Nlrp1a |
T |
C |
11: 71,004,466 (GRCm39) |
|
probably null |
Het |
| Npffr2 |
A |
T |
5: 89,730,879 (GRCm39) |
K270* |
probably null |
Het |
| Or10a3 |
T |
G |
7: 108,480,689 (GRCm39) |
E41D |
probably benign |
Het |
| Or2b6 |
T |
A |
13: 21,823,340 (GRCm39) |
M118L |
possibly damaging |
Het |
| Or51e1 |
T |
A |
7: 102,359,378 (GRCm39) |
I304N |
probably damaging |
Het |
| Or8g26 |
T |
A |
9: 39,095,664 (GRCm39) |
Y60* |
probably null |
Het |
| Or8k40 |
C |
T |
2: 86,584,155 (GRCm39) |
C309Y |
probably benign |
Het |
| Otub2 |
T |
A |
12: 103,359,103 (GRCm39) |
L64Q |
probably benign |
Het |
| Pabpc4l |
C |
G |
3: 46,400,570 (GRCm39) |
G358A |
possibly damaging |
Het |
| Pabpc4l |
C |
T |
3: 46,400,579 (GRCm39) |
R355H |
probably benign |
Het |
| Parp1 |
T |
C |
1: 180,417,033 (GRCm39) |
S606P |
probably damaging |
Het |
| Pkhd1 |
A |
G |
1: 20,594,354 (GRCm39) |
V1253A |
probably benign |
Het |
| Psg29 |
G |
A |
7: 16,942,458 (GRCm39) |
R153H |
probably benign |
Het |
| Rbm25 |
A |
G |
12: 83,691,181 (GRCm39) |
M58V |
possibly damaging |
Het |
| Rbm28 |
T |
C |
6: 29,125,353 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,671,933 (GRCm39) |
S3436P |
possibly damaging |
Het |
| Slc3a1 |
A |
G |
17: 85,354,181 (GRCm39) |
I335V |
probably benign |
Het |
| Slc4a4 |
T |
C |
5: 89,373,753 (GRCm39) |
F953S |
probably damaging |
Het |
| Spata20 |
A |
G |
11: 94,375,404 (GRCm39) |
I130T |
possibly damaging |
Het |
| Spata31h1 |
T |
C |
10: 82,119,481 (GRCm39) |
T4510A |
possibly damaging |
Het |
| Srcap |
T |
C |
7: 127,148,471 (GRCm39) |
S1879P |
probably damaging |
Het |
| Stard3nl |
A |
T |
13: 19,551,948 (GRCm39) |
M166K |
probably benign |
Het |
| Stard3nl |
G |
A |
13: 19,560,736 (GRCm39) |
T13M |
probably damaging |
Het |
| Stil |
A |
G |
4: 114,863,979 (GRCm39) |
T74A |
probably benign |
Het |
| Syt6 |
T |
G |
3: 103,532,972 (GRCm39) |
M367R |
probably damaging |
Het |
| Tacc1 |
T |
C |
8: 25,672,581 (GRCm39) |
T125A |
possibly damaging |
Het |
| Tbc1d8 |
G |
A |
1: 39,441,959 (GRCm39) |
T211I |
possibly damaging |
Het |
| Tcaf1 |
A |
G |
6: 42,663,809 (GRCm39) |
S24P |
probably benign |
Het |
| Trim75 |
T |
G |
8: 65,435,199 (GRCm39) |
Y417S |
probably damaging |
Het |
| Ttll12 |
T |
C |
15: 83,464,321 (GRCm39) |
Y503C |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,641,587 (GRCm39) |
L5176Q |
possibly damaging |
Het |
| Ubqlnl |
C |
T |
7: 103,798,925 (GRCm39) |
V191M |
probably benign |
Het |
| Unc5c |
A |
T |
3: 141,522,692 (GRCm39) |
Y706F |
probably benign |
Het |
| Zfp593 |
T |
C |
4: 133,972,077 (GRCm39) |
|
probably benign |
Het |
| Zfp956 |
T |
C |
6: 47,939,476 (GRCm39) |
S175P |
probably damaging |
Het |
|
| Other mutations in St18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:St18
|
APN |
1 |
6,872,796 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00840:St18
|
APN |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01016:St18
|
APN |
1 |
6,914,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01116:St18
|
APN |
1 |
6,872,856 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01719:St18
|
APN |
1 |
6,916,020 (GRCm39) |
splice site |
probably benign |
|
|
IGL01885:St18
|
APN |
1 |
6,914,596 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02486:St18
|
APN |
1 |
6,890,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02611:St18
|
APN |
1 |
6,839,114 (GRCm39) |
splice site |
probably benign |
|
|
IGL02742:St18
|
APN |
1 |
6,872,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02953:St18
|
APN |
1 |
6,914,337 (GRCm39) |
splice site |
probably benign |
|
|
IGL02999:St18
|
APN |
1 |
6,887,829 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03092:St18
|
APN |
1 |
6,839,118 (GRCm39) |
splice site |
probably benign |
|
|
Smallish
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03055:St18
|
UTSW |
1 |
6,872,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0089:St18
|
UTSW |
1 |
6,919,172 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0257:St18
|
UTSW |
1 |
6,890,186 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0383:St18
|
UTSW |
1 |
6,873,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0588:St18
|
UTSW |
1 |
6,887,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0989:St18
|
UTSW |
1 |
6,898,105 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1068:St18
|
UTSW |
1 |
6,865,786 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1311:St18
|
UTSW |
1 |
6,915,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:St18
|
UTSW |
1 |
6,915,793 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1723:St18
|
UTSW |
1 |
6,880,909 (GRCm39) |
splice site |
probably benign |
|
|
R1926:St18
|
UTSW |
1 |
6,872,913 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1927:St18
|
UTSW |
1 |
6,872,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2035:St18
|
UTSW |
1 |
6,872,552 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:St18
|
UTSW |
1 |
6,898,195 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2139:St18
|
UTSW |
1 |
6,880,839 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2261:St18
|
UTSW |
1 |
6,915,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2300:St18
|
UTSW |
1 |
6,925,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2322:St18
|
UTSW |
1 |
6,914,348 (GRCm39) |
nonsense |
probably null |
|
|
R2846:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3738:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3739:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3772:St18
|
UTSW |
1 |
6,914,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3805:St18
|
UTSW |
1 |
6,872,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:St18
|
UTSW |
1 |
6,873,117 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4034:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4036:St18
|
UTSW |
1 |
6,898,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4407:St18
|
UTSW |
1 |
6,898,061 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4527:St18
|
UTSW |
1 |
6,925,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:St18
|
UTSW |
1 |
6,873,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5182:St18
|
UTSW |
1 |
6,887,877 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5186:St18
|
UTSW |
1 |
6,872,541 (GRCm39) |
splice site |
probably null |
|
|
R5354:St18
|
UTSW |
1 |
6,914,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5423:St18
|
UTSW |
1 |
6,872,840 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5724:St18
|
UTSW |
1 |
6,841,174 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6182:St18
|
UTSW |
1 |
6,914,342 (GRCm39) |
splice site |
probably null |
|
|
R6491:St18
|
UTSW |
1 |
6,898,209 (GRCm39) |
nonsense |
probably null |
|
|
R6503:St18
|
UTSW |
1 |
6,865,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7037:St18
|
UTSW |
1 |
6,873,260 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7098:St18
|
UTSW |
1 |
6,898,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:St18
|
UTSW |
1 |
6,929,351 (GRCm39) |
missense |
|
|
|
R7144:St18
|
UTSW |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7150:St18
|
UTSW |
1 |
6,873,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7334:St18
|
UTSW |
1 |
6,872,783 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7502:St18
|
UTSW |
1 |
6,898,194 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7729:St18
|
UTSW |
1 |
6,872,761 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7848:St18
|
UTSW |
1 |
6,927,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8088:St18
|
UTSW |
1 |
6,898,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8299:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8338:St18
|
UTSW |
1 |
6,879,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8690:St18
|
UTSW |
1 |
6,872,788 (GRCm39) |
missense |
probably benign |
|
|
R8753:St18
|
UTSW |
1 |
6,916,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8808:St18
|
UTSW |
1 |
6,880,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8880:St18
|
UTSW |
1 |
6,865,619 (GRCm39) |
nonsense |
probably null |
|
|
R9055:St18
|
UTSW |
1 |
6,873,206 (GRCm39) |
nonsense |
probably null |
|
|
R9292:St18
|
UTSW |
1 |
6,898,106 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9322:St18
|
UTSW |
1 |
6,865,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9530:St18
|
UTSW |
1 |
6,872,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9603:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9611:St18
|
UTSW |
1 |
6,873,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:St18
|
UTSW |
1 |
6,929,246 (GRCm39) |
missense |
|
|
|
R9644:St18
|
UTSW |
1 |
6,929,276 (GRCm39) |
missense |
|
|
|
R9740:St18
|
UTSW |
1 |
6,873,287 (GRCm39) |
nonsense |
probably null |
|
|
R9750:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTTTTACTGGTGGCAGATTTGAAC -3'
(R):5'- CATTCAGGAAATGGTGGTGC -3'
Sequencing Primer
(F):5'- TTTGAACACAGAAGATGCAGC -3'
(R):5'- CATTCAGGAAATGGTGGTGCTTTTTG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation