Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02793:Mphosph9'

359855

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mphosph9

Ensembl Gene

ENSMUSG00000038126

Gene Name

M-phase phosphoprotein 9

Synonyms

4930548D04Rik, MPP9, B930097C17Rik, 9630025B04Rik, MPP-9

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02793

Quality Score

Status

Chromosome

Chromosomal Location

124389022-124466001 bp(-) (GRCm39)

Type of Mutation

critical splice acceptor site

DNA Base Change (assembly)

T to A at 124421800 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000138982 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000031344] [ENSMUST00000147737] [ENSMUST00000184951]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000031344

SMART Domains

Protein: ENSMUSP00000031344
Gene: ENSMUSG00000038126

Domain	Start	End	E-Value	Type
low complexity region	102	119	N/A	INTRINSIC
low complexity region	128	140	N/A	INTRINSIC
low complexity region	414	428	N/A	INTRINSIC
coiled coil region	574	736	N/A	INTRINSIC
low complexity region	879	898	N/A	INTRINSIC
low complexity region	957	971	N/A	INTRINSIC
coiled coil region	1040	1105	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000147737

Predicted Effect

probably null
Transcript: ENSMUST00000184951

SMART Domains

Protein: ENSMUSP00000138982
Gene: ENSMUSG00000038126

Domain	Start	End	E-Value	Type
coiled coil region	102	130	N/A	INTRINSIC
low complexity region	132	149	N/A	INTRINSIC
low complexity region	158	170	N/A	INTRINSIC
low complexity region	444	458	N/A	INTRINSIC
coiled coil region	604	766	N/A	INTRINSIC
low complexity region	909	928	N/A	INTRINSIC
low complexity region	987	1001	N/A	INTRINSIC
coiled coil region	1070	1135	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000200032

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb11	T	C	2: 69,122,293 (GRCm39)	I397V	possibly damaging	Het
Bco2	A	T	9: 50,455,834 (GRCm39)	V173E	probably damaging	Het
Bdnf	T	C	2: 109,554,196 (GRCm39)	V150A	probably damaging	Het
Cdh15	T	A	8: 123,587,721 (GRCm39)	V215E	probably damaging	Het
Col6a2	A	T	10: 76,432,144 (GRCm39)	I1003N	possibly damaging	Het
Daam2	A	C	17: 49,771,056 (GRCm39)	I887S	probably damaging	Het
Dnajb13	C	T	7: 100,156,648 (GRCm39)	D143N	probably damaging	Het
Fabp3-ps1	T	A	10: 86,567,943 (GRCm39)		probably benign	Het
Gid4	G	A	11: 60,323,256 (GRCm39)	R116Q	probably benign	Het
Hectd2	A	G	19: 36,564,821 (GRCm39)	E34G	probably damaging	Het
Hyal6	A	T	6: 24,734,378 (GRCm39)	K104*	probably null	Het
Il1b	A	G	2: 129,209,171 (GRCm39)	I153T	probably benign	Het
Kdm3b	A	G	18: 34,962,072 (GRCm39)	M1499V	probably damaging	Het
Kntc1	C	A	5: 123,916,340 (GRCm39)		probably null	Het
Lmbr1	A	G	5: 29,497,186 (GRCm39)	S72P	probably damaging	Het
Lrrc2	T	C	9: 110,808,695 (GRCm39)		probably null	Het
Map2k5	T	C	9: 63,164,321 (GRCm39)	I328V	probably benign	Het
Mpp4	C	T	1: 59,175,993 (GRCm39)		probably null	Het
Ndrg3	A	G	2: 156,791,952 (GRCm39)		probably null	Het
Ndufa10	A	C	1: 92,397,639 (GRCm39)	Y136D	probably damaging	Het
Or10ak9	A	T	4: 118,726,794 (GRCm39)	D271V	probably damaging	Het
Or2b7	T	A	13: 21,740,172 (GRCm39)	S7C	probably damaging	Het
Or4a72	T	C	2: 89,405,896 (GRCm39)	Y58C	probably damaging	Het
Or8g34	A	G	9: 39,372,802 (GRCm39)	E22G	probably benign	Het
Rab18	T	C	18: 6,788,474 (GRCm39)		probably benign	Het
Rad1	T	C	15: 10,493,365 (GRCm39)	I264T	probably benign	Het
Rhbdf1	A	G	11: 32,163,293 (GRCm39)	V393A	possibly damaging	Het
Rrp12	A	G	19: 41,860,005 (GRCm39)	L1025P	probably damaging	Het
Rtca	A	G	3: 116,286,726 (GRCm39)	F302S	probably damaging	Het
Slc9b1	T	A	3: 135,080,167 (GRCm39)		probably benign	Het
Sspo	A	T	6: 48,464,828 (GRCm39)		probably benign	Het
Ssrp1	T	A	2: 84,871,264 (GRCm39)	I257N	probably damaging	Het
Sval2	A	C	6: 41,838,795 (GRCm39)	Y11S	probably benign	Het
Tcl1b2	T	C	12: 105,120,358 (GRCm39)	*118Q	probably null	Het
Thsd7b	A	G	1: 129,879,130 (GRCm39)	Y989C	probably damaging	Het
Tlr4	A	C	4: 66,757,681 (GRCm39)	H158P	probably damaging	Het
Vmn2r42	T	C	7: 8,197,852 (GRCm39)	T256A	probably benign	Het
Xdh	T	C	17: 74,207,576 (GRCm39)	E927G	probably damaging	Het
Yap1	T	C	9: 7,973,907 (GRCm39)	N178S	probably benign	Het

Other mutations in Mphosph9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01363:Mphosph9	APN	5	124,400,084 (GRCm39)	missense	probably damaging	1.00
IGL01527:Mphosph9	APN	5	124,421,687 (GRCm39)	splice site	probably benign
IGL01784:Mphosph9	APN	5	124,403,373 (GRCm39)	splice site	probably benign
IGL01958:Mphosph9	APN	5	124,463,053 (GRCm39)	utr 5 prime	probably benign
IGL02020:Mphosph9	APN	5	124,397,013 (GRCm39)	missense	probably damaging	0.99
IGL02190:Mphosph9	APN	5	124,403,488 (GRCm39)	missense	possibly damaging	0.92
IGL02261:Mphosph9	APN	5	124,398,150 (GRCm39)	missense	probably damaging	1.00
IGL02569:Mphosph9	APN	5	124,435,634 (GRCm39)	nonsense	probably null
IGL02640:Mphosph9	APN	5	124,453,563 (GRCm39)	missense	possibly damaging	0.66
IGL02702:Mphosph9	APN	5	124,398,052 (GRCm39)	missense	probably damaging	1.00
IGL02813:Mphosph9	APN	5	124,453,691 (GRCm39)	missense	probably benign	0.37
IGL02875:Mphosph9	APN	5	124,421,800 (GRCm39)	critical splice acceptor site	probably null
IGL03149:Mphosph9	APN	5	124,401,074 (GRCm39)	missense	probably damaging	1.00
PIT4445001:Mphosph9	UTSW	5	124,436,853 (GRCm39)	missense	possibly damaging	0.82
R0304:Mphosph9	UTSW	5	124,436,892 (GRCm39)	missense	probably benign	0.01
R0437:Mphosph9	UTSW	5	124,453,631 (GRCm39)	missense	probably benign	0.27
R0483:Mphosph9	UTSW	5	124,445,033 (GRCm39)	nonsense	probably null
R0811:Mphosph9	UTSW	5	124,436,822 (GRCm39)	missense	probably damaging	1.00
R0812:Mphosph9	UTSW	5	124,436,822 (GRCm39)	missense	probably damaging	1.00
R0942:Mphosph9	UTSW	5	124,400,100 (GRCm39)	nonsense	probably null
R1175:Mphosph9	UTSW	5	124,453,739 (GRCm39)	missense	possibly damaging	0.94
R1372:Mphosph9	UTSW	5	124,421,808 (GRCm39)	splice site	probably null
R1442:Mphosph9	UTSW	5	124,403,461 (GRCm39)	missense	possibly damaging	0.62
R1533:Mphosph9	UTSW	5	124,405,204 (GRCm39)	missense	probably damaging	1.00
R1959:Mphosph9	UTSW	5	124,453,764 (GRCm39)	missense	possibly damaging	0.92
R2036:Mphosph9	UTSW	5	124,442,274 (GRCm39)	missense	probably damaging	0.97
R2256:Mphosph9	UTSW	5	124,421,722 (GRCm39)	missense	probably benign	0.00
R2919:Mphosph9	UTSW	5	124,399,069 (GRCm39)	missense	probably benign	0.22
R2920:Mphosph9	UTSW	5	124,399,069 (GRCm39)	missense	probably benign	0.22
R4064:Mphosph9	UTSW	5	124,428,980 (GRCm39)	missense	probably damaging	1.00
R4272:Mphosph9	UTSW	5	124,442,266 (GRCm39)	missense	probably damaging	0.96
R4430:Mphosph9	UTSW	5	124,403,509 (GRCm39)	missense	possibly damaging	0.83
R4883:Mphosph9	UTSW	5	124,437,108 (GRCm39)	missense	probably damaging	1.00
R4992:Mphosph9	UTSW	5	124,442,253 (GRCm39)	missense	probably damaging	1.00
R5815:Mphosph9	UTSW	5	124,453,481 (GRCm39)	missense	probably damaging	1.00
R5993:Mphosph9	UTSW	5	124,454,161 (GRCm39)	missense	probably benign	0.40
R6102:Mphosph9	UTSW	5	124,435,772 (GRCm39)	missense	possibly damaging	0.86
R6295:Mphosph9	UTSW	5	124,458,978 (GRCm39)	missense	possibly damaging	0.46
R6320:Mphosph9	UTSW	5	124,463,024 (GRCm39)	missense	probably damaging	0.99
R6628:Mphosph9	UTSW	5	124,436,825 (GRCm39)	missense	probably damaging	0.98
R6692:Mphosph9	UTSW	5	124,398,179 (GRCm39)	missense	probably damaging	1.00
R6705:Mphosph9	UTSW	5	124,429,027 (GRCm39)	missense	possibly damaging	0.83
R6747:Mphosph9	UTSW	5	124,435,762 (GRCm39)	missense	possibly damaging	0.93
R6787:Mphosph9	UTSW	5	124,399,090 (GRCm39)	missense	probably damaging	0.99
R6850:Mphosph9	UTSW	5	124,399,019 (GRCm39)	missense	probably damaging	1.00
R6956:Mphosph9	UTSW	5	124,435,621 (GRCm39)	missense	probably damaging	1.00
R7075:Mphosph9	UTSW	5	124,458,922 (GRCm39)	missense	probably damaging	0.99
R7604:Mphosph9	UTSW	5	124,454,180 (GRCm39)	missense	probably benign	0.01
R7789:Mphosph9	UTSW	5	124,453,650 (GRCm39)	missense	probably damaging	1.00
R7808:Mphosph9	UTSW	5	124,399,009 (GRCm39)	missense	probably damaging	0.99
R7823:Mphosph9	UTSW	5	124,442,319 (GRCm39)	missense	probably damaging	0.99
R7891:Mphosph9	UTSW	5	124,428,967 (GRCm39)	missense	probably damaging	1.00
R8210:Mphosph9	UTSW	5	124,405,174 (GRCm39)	missense	probably damaging	1.00
R8256:Mphosph9	UTSW	5	124,393,169 (GRCm39)	missense	probably damaging	1.00
R8385:Mphosph9	UTSW	5	124,450,785 (GRCm39)	missense	probably benign	0.19
R8438:Mphosph9	UTSW	5	124,430,455 (GRCm39)	missense	probably benign	0.19
R8692:Mphosph9	UTSW	5	124,450,875 (GRCm39)	missense	probably damaging	0.99
R8790:Mphosph9	UTSW	5	124,453,736 (GRCm39)	missense	probably damaging	1.00
R8818:Mphosph9	UTSW	5	124,463,027 (GRCm39)	nonsense	probably null
R8847:Mphosph9	UTSW	5	124,454,209 (GRCm39)	missense	possibly damaging	0.91
R9018:Mphosph9	UTSW	5	124,436,713 (GRCm39)	missense	probably benign	0.12
R9208:Mphosph9	UTSW	5	124,450,854 (GRCm39)	missense	probably damaging	0.97
R9221:Mphosph9	UTSW	5	124,403,427 (GRCm39)	missense	probably benign	0.10
R9603:Mphosph9	UTSW	5	124,463,015 (GRCm39)	nonsense	probably null
R9721:Mphosph9	UTSW	5	124,436,738 (GRCm39)	missense	possibly damaging	0.87

Posted On

2015-12-18