Incidental Mutation 'IGL02804:Troap'
| ID |
360361 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Troap
|
| Ensembl Gene |
ENSMUSG00000032783 |
| Gene Name |
trophinin associated protein |
| Synonyms |
tastin, E130301L11Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.079)
|
| Stock # |
IGL02804
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
15 |
| Chromosomal Location |
98972854-98981290 bp(+) (GRCm39) |
| Type of Mutation |
splice site (5 bp from exon) |
| DNA Base Change (assembly) |
G to A
at 98975552 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000155404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039665]
[ENSMUST00000230054]
|
| AlphaFold |
B7ZNG4 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000039665
|
| SMART Domains |
Protein: ENSMUSP00000035389
Gene: ENSMUSG00000032783
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
232 |
246 |
N/A |
INTRINSIC |
|
low complexity region
|
390 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
468 |
479 |
N/A |
INTRINSIC |
|
low complexity region
|
499 |
511 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183449
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000229740
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000230027
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000230054
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000230311
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000230868
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 30 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm4 |
A |
T |
4: 144,397,009 (GRCm39) |
I241N |
possibly damaging |
Het |
| Aftph |
T |
C |
11: 20,676,107 (GRCm39) |
T501A |
possibly damaging |
Het |
| Agrn |
A |
G |
4: 156,258,512 (GRCm39) |
S985P |
probably benign |
Het |
| Atxn7l1 |
T |
A |
12: 33,417,788 (GRCm39) |
S650T |
probably damaging |
Het |
| Camk2d |
G |
A |
3: 126,591,387 (GRCm39) |
E286K |
possibly damaging |
Het |
| Card10 |
A |
G |
15: 78,686,649 (GRCm39) |
V56A |
probably damaging |
Het |
| Fcgbpl1 |
G |
T |
7: 27,852,795 (GRCm39) |
V1361L |
probably benign |
Het |
| H2-Q10 |
G |
A |
17: 35,784,147 (GRCm39) |
G263R |
probably damaging |
Het |
| Herc4 |
A |
C |
10: 63,121,454 (GRCm39) |
K365Q |
probably benign |
Het |
| Klhl33 |
T |
C |
14: 51,130,411 (GRCm39) |
H101R |
probably damaging |
Het |
| Lef1 |
A |
G |
3: 130,988,338 (GRCm39) |
N236D |
probably damaging |
Het |
| Lipg |
T |
A |
18: 75,082,159 (GRCm39) |
N255Y |
probably damaging |
Het |
| Lrp5 |
T |
C |
19: 3,650,777 (GRCm39) |
D1219G |
possibly damaging |
Het |
| Myh7b |
T |
C |
2: 155,467,643 (GRCm39) |
L756P |
probably damaging |
Het |
| Nnt |
A |
G |
13: 119,518,210 (GRCm39) |
|
probably null |
Het |
| Or6c88 |
T |
C |
10: 129,407,306 (GRCm39) |
S261P |
possibly damaging |
Het |
| Pcsk9 |
A |
G |
4: 106,314,161 (GRCm39) |
Y145H |
probably damaging |
Het |
| Prkag1 |
G |
A |
15: 98,713,385 (GRCm39) |
S69L |
probably damaging |
Het |
| Prkd2 |
C |
A |
7: 16,589,815 (GRCm39) |
R506S |
probably benign |
Het |
| Ralgapb |
T |
A |
2: 158,268,204 (GRCm39) |
D102E |
possibly damaging |
Het |
| Rbm44 |
A |
G |
1: 91,077,898 (GRCm39) |
|
probably benign |
Het |
| Snap23 |
T |
C |
2: 120,416,637 (GRCm39) |
|
probably benign |
Het |
| Sntg1 |
T |
A |
1: 8,874,182 (GRCm39) |
|
probably benign |
Het |
| Speer4a2 |
T |
A |
5: 26,291,429 (GRCm39) |
K126* |
probably null |
Het |
| Strbp |
T |
C |
2: 37,514,498 (GRCm39) |
|
probably benign |
Het |
| Tmem217 |
G |
A |
17: 29,745,455 (GRCm39) |
L92F |
probably damaging |
Het |
| Vmn1r16 |
T |
C |
6: 57,300,467 (GRCm39) |
M52V |
probably benign |
Het |
| Wwox |
G |
A |
8: 115,438,753 (GRCm39) |
G273E |
probably damaging |
Het |
| Zbp1 |
T |
A |
2: 173,050,939 (GRCm39) |
K310N |
probably damaging |
Het |
| Zfp423 |
T |
A |
8: 88,509,285 (GRCm39) |
H332L |
probably benign |
Het |
|
| Other mutations in Troap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01140:Troap
|
APN |
15 |
98,980,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01949:Troap
|
APN |
15 |
98,979,102 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL02468:Troap
|
APN |
15 |
98,973,242 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL03224:Troap
|
APN |
15 |
98,979,758 (GRCm39) |
missense |
probably benign |
|
|
R0617:Troap
|
UTSW |
15 |
98,980,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1085:Troap
|
UTSW |
15 |
98,980,044 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1872:Troap
|
UTSW |
15 |
98,973,233 (GRCm39) |
splice site |
probably benign |
|
|
R1884:Troap
|
UTSW |
15 |
98,975,779 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1937:Troap
|
UTSW |
15 |
98,975,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2063:Troap
|
UTSW |
15 |
98,980,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2065:Troap
|
UTSW |
15 |
98,980,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2066:Troap
|
UTSW |
15 |
98,980,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2068:Troap
|
UTSW |
15 |
98,980,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2087:Troap
|
UTSW |
15 |
98,976,698 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2159:Troap
|
UTSW |
15 |
98,975,467 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4282:Troap
|
UTSW |
15 |
98,976,713 (GRCm39) |
missense |
probably benign |
|
|
R5296:Troap
|
UTSW |
15 |
98,976,698 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5557:Troap
|
UTSW |
15 |
98,973,675 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5652:Troap
|
UTSW |
15 |
98,980,145 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5764:Troap
|
UTSW |
15 |
98,973,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6891:Troap
|
UTSW |
15 |
98,980,569 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8008:Troap
|
UTSW |
15 |
98,973,511 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9319:Troap
|
UTSW |
15 |
98,975,444 (GRCm39) |
missense |
probably benign |
0.01 |
|
RF012:Troap
|
UTSW |
15 |
98,973,281 (GRCm39) |
missense |
probably benign |
0.10 |
|
Z1177:Troap
|
UTSW |
15 |
98,975,458 (GRCm39) |
missense |
probably null |
|
|
| Posted On |
2015-12-18 |
Incidental Mutation