Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02805:Zscan4d'

360397

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zscan4d

Ensembl Gene

ENSMUSG00000090714

Gene Name

zinc finger and SCAN domain containing 4D

Synonyms

EG545913

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.135) question?

Stock #

IGL02805

Quality Score

Status

Chromosome

Chromosomal Location

10895570-10900075 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to G at 10898897 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000066504 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000067210]

AlphaFold

A7KBS4

Predicted Effect

probably benign
Transcript: ENSMUST00000067210

SMART Domains

Protein: ENSMUSP00000066504
Gene: ENSMUSG00000090714

Domain	Start	End	E-Value	Type
Pfam:SCAN	39	126	2.5e-19	PFAM
low complexity region	181	197	N/A	INTRINSIC
ZnF_C2H2	395	417	5.14e-3	SMART
ZnF_C2H2	424	446	7.68e0	SMART
ZnF_C2H2	452	474	4.17e-3	SMART
ZnF_C2H2	480	503	3.83e-2	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000209835

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acaca	T	C	11: 84,113,959 (GRCm39)		probably benign	Het
Ankdd1b	A	G	13: 96,580,810 (GRCm39)	S163P	probably benign	Het
Ap5z1	G	A	5: 142,456,038 (GRCm39)		probably benign	Het
Asb14	A	G	14: 26,623,144 (GRCm39)	N172S	possibly damaging	Het
Avil	G	A	10: 126,843,486 (GRCm39)	V139I	possibly damaging	Het
C130073F10Rik	A	T	4: 101,748,171 (GRCm39)	M1K	probably null	Het
Ccdc33	T	A	9: 58,005,874 (GRCm39)	I37F	probably benign	Het
Ccdc9	T	C	7: 16,009,199 (GRCm39)	M550V	probably benign	Het
Cfap119	T	C	7: 127,185,566 (GRCm39)	D121G	possibly damaging	Het
Cgn	T	A	3: 94,681,687 (GRCm39)	L469F	probably damaging	Het
Dnaaf3	C	T	7: 4,526,704 (GRCm39)	G458R	possibly damaging	Het
Dscaml1	T	A	9: 45,359,195 (GRCm39)	N151K	probably damaging	Het
Dsel	A	G	1: 111,790,046 (GRCm39)	V163A	probably damaging	Het
Epg5	A	G	18: 78,073,406 (GRCm39)		probably benign	Het
Fanca	A	T	8: 124,016,233 (GRCm39)	I670N	probably damaging	Het
Fsip2	T	C	2: 82,823,839 (GRCm39)	V6524A	probably benign	Het
Gm10985	T	C	3: 53,752,514 (GRCm39)		probably null	Het
Gm1818	C	T	12: 48,602,518 (GRCm39)		noncoding transcript	Het
Hars2	C	T	18: 36,920,630 (GRCm39)	R158*	probably null	Het
Htr5b	A	G	1: 121,455,617 (GRCm39)	V101A	probably damaging	Het
Ipp	A	G	4: 116,386,885 (GRCm39)	I356V	possibly damaging	Het
Itga8	T	A	2: 12,194,291 (GRCm39)	N703I	possibly damaging	Het
Or8b3	T	A	9: 38,315,132 (GRCm39)		probably benign	Het
Ppp6r3	T	C	19: 3,542,428 (GRCm39)	N406D	probably benign	Het
Rbbp6	G	A	7: 122,600,411 (GRCm39)		probably benign	Het
Rgs7	T	C	1: 174,977,262 (GRCm39)	Y114C	probably damaging	Het
Ripor1	A	G	8: 106,344,203 (GRCm39)	T446A	probably damaging	Het
Rnf213	A	G	11: 119,325,892 (GRCm39)	D1562G	probably damaging	Het
Scaf11	A	T	15: 96,318,063 (GRCm39)	D500E	possibly damaging	Het
Spock1	A	G	13: 58,055,391 (GRCm39)	I4T	possibly damaging	Het
Srebf2	C	A	15: 82,054,045 (GRCm39)	N35K	probably benign	Het
Srgap3	G	T	6: 112,704,224 (GRCm39)	H922N	probably damaging	Het
Stk32c	A	C	7: 138,701,762 (GRCm39)	H112Q	probably damaging	Het
Styxl2	T	C	1: 165,926,630 (GRCm39)	E994G	probably damaging	Het
Thumpd3	A	G	6: 113,043,758 (GRCm39)	D391G	probably damaging	Het
Vmn2r38	T	A	7: 9,078,546 (GRCm39)	H612L	probably damaging	Het
Vsig10l	T	G	7: 43,114,666 (GRCm39)	I289S	probably damaging	Het
Wwox	G	A	8: 115,438,753 (GRCm39)	G273E	probably damaging	Het

Other mutations in Zscan4d

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00518:Zscan4d	APN	7	10,896,281 (GRCm39)	missense	probably benign	0.00
IGL01576:Zscan4d	APN	7	10,896,519 (GRCm39)	missense	possibly damaging	0.91
IGL01926:Zscan4d	APN	7	10,898,921 (GRCm39)	missense	probably damaging	0.98
IGL02008:Zscan4d	APN	7	10,896,296 (GRCm39)	missense	probably benign	0.00
IGL02245:Zscan4d	APN	7	10,896,716 (GRCm39)	missense	probably benign
IGL02473:Zscan4d	APN	7	10,896,336 (GRCm39)	missense	probably benign	0.04
IGL03010:Zscan4d	APN	7	10,897,070 (GRCm39)	missense	probably damaging	0.98
IGL03383:Zscan4d	APN	7	10,896,692 (GRCm39)	missense	probably benign	0.07
R0626:Zscan4d	UTSW	7	10,898,946 (GRCm39)	missense	probably damaging	0.97
R1084:Zscan4d	UTSW	7	10,898,932 (GRCm39)	missense	probably damaging	0.99
R1457:Zscan4d	UTSW	7	10,898,921 (GRCm39)	missense	probably damaging	0.98
R2426:Zscan4d	UTSW	7	10,899,022 (GRCm39)	missense	probably damaging	0.99
R2912:Zscan4d	UTSW	7	10,896,614 (GRCm39)	missense	probably benign
R3736:Zscan4d	UTSW	7	10,896,803 (GRCm39)	missense	probably benign
R4379:Zscan4d	UTSW	7	10,898,905 (GRCm39)	missense	probably benign
R4580:Zscan4d	UTSW	7	10,896,435 (GRCm39)	missense	probably benign	0.00
R4765:Zscan4d	UTSW	7	10,896,594 (GRCm39)	missense	probably benign	0.08
R4975:Zscan4d	UTSW	7	10,899,274 (GRCm39)	start codon destroyed	probably null	0.02
R6452:Zscan4d	UTSW	7	10,895,999 (GRCm39)	missense	probably damaging	0.98
R6570:Zscan4d	UTSW	7	10,895,927 (GRCm39)	missense	possibly damaging	0.92
R6680:Zscan4d	UTSW	7	10,896,366 (GRCm39)	missense	possibly damaging	0.85
R7726:Zscan4d	UTSW	7	10,899,169 (GRCm39)	missense	possibly damaging	0.65
R7772:Zscan4d	UTSW	7	10,896,770 (GRCm39)	missense	probably benign	0.28
R8282:Zscan4d	UTSW	7	10,896,369 (GRCm39)	missense	possibly damaging	0.91
R8320:Zscan4d	UTSW	7	10,799,942 (GRCm39)	missense	probably benign	0.00
R9671:Zscan4d	UTSW	7	10,898,945 (GRCm39)	missense	probably damaging	0.97
R9770:Zscan4d	UTSW	7	10,896,036 (GRCm39)	missense	probably benign	0.33

Posted On

2015-12-18