Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02829:Vmn2r2'

361363

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r2

Ensembl Gene

ENSMUSG00000043897

Gene Name

vomeronasal 2, receptor 2

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

IGL02829

Quality Score

Status

Chromosome

Chromosomal Location

64022699-64049349 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 64026172 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000135110 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000077958] [ENSMUST00000177151]

AlphaFold

L7N2E9

Predicted Effect

probably benign
Transcript: ENSMUST00000077958

SMART Domains

Protein: ENSMUSP00000077109
Gene: ENSMUSG00000043897

Domain	Start	End	E-Value	Type
Pfam:ANF_receptor	1	416	4.5e-80	PFAM
Pfam:NCD3G	458	511	8.3e-18	PFAM
Pfam:7tm_3	542	779	1.3e-75	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000177151

SMART Domains

Protein: ENSMUSP00000135110
Gene: ENSMUSG00000043897

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Pfam:ANF_receptor	83	500	1.6e-84	PFAM
Pfam:NCD3G	542	595	2.6e-17	PFAM
Pfam:7tm_3	628	862	1.9e-47	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Bbs9	A	G	9: 22,490,780 (GRCm39)	T303A	probably damaging	Het
Bet1	T	A	6: 4,086,795 (GRCm39)	M1L	probably benign	Het
Bicc1	A	C	10: 70,794,710 (GRCm39)	V149G	probably damaging	Het
Braf	C	A	6: 39,604,662 (GRCm39)	L655F	possibly damaging	Het
Cd101	A	G	3: 100,925,881 (GRCm39)		probably benign	Het
Cobll1	T	C	2: 64,956,389 (GRCm39)	K290E	probably damaging	Het
Col6a5	A	T	9: 105,811,506 (GRCm39)	I671K	unknown	Het
D130052B06Rik	A	C	11: 33,573,864 (GRCm39)	T154P	probably benign	Het
Dglucy	A	C	12: 100,837,663 (GRCm39)	H602P	probably damaging	Het
Fbxo34	A	G	14: 47,767,146 (GRCm39)	I220V	probably benign	Het
Gm42878	A	G	5: 121,675,266 (GRCm39)	V101A	probably damaging	Het
Gsdmc4	A	G	15: 63,764,497 (GRCm39)	L381P	probably benign	Het
Ifi208	C	A	1: 173,510,406 (GRCm39)	P187H	probably damaging	Het
Lrrc37a	A	T	11: 103,382,000 (GRCm39)	C2473S	unknown	Het
Miip	T	A	4: 147,947,518 (GRCm39)	N214I	probably benign	Het
Mrc2	A	G	11: 105,227,533 (GRCm39)	T589A	possibly damaging	Het
Mtss1	A	G	15: 58,930,277 (GRCm39)		probably benign	Het
Mypn	T	C	10: 63,028,365 (GRCm39)	R233G	probably benign	Het
Naip6	A	T	13: 100,437,273 (GRCm39)	C417S	probably benign	Het
Or13f5	C	T	4: 52,826,027 (GRCm39)	P210L	probably damaging	Het
Or4c111	A	C	2: 88,844,021 (GRCm39)	L129W	probably damaging	Het
Or8k37	T	A	2: 86,469,599 (GRCm39)	Y151F	possibly damaging	Het
Pcsk1	T	C	13: 75,274,955 (GRCm39)	Y515H	probably damaging	Het
Pla2g2e	T	A	4: 138,607,747 (GRCm39)	Y42*	probably null	Het
Polh	A	T	17: 46,483,828 (GRCm39)	L479Q	possibly damaging	Het
Prr36	T	A	8: 4,265,278 (GRCm39)	R157S	possibly damaging	Het
Reck	T	A	4: 43,891,014 (GRCm39)	C51S	probably damaging	Het
Rev3l	A	G	10: 39,701,236 (GRCm39)	D1911G	probably damaging	Het
Scgb1b27	A	T	7: 33,721,173 (GRCm39)		probably null	Het
Sema4g	G	A	19: 44,981,188 (GRCm39)	R47Q	possibly damaging	Het
Serinc1	A	T	10: 57,400,061 (GRCm39)	Y158*	probably null	Het
Slc15a2	C	A	16: 36,577,555 (GRCm39)	G435C	possibly damaging	Het
Tbc1d17	C	A	7: 44,498,296 (GRCm39)		probably benign	Het
Tenm4	C	T	7: 96,544,205 (GRCm39)	Q2074*	probably null	Het
Tns3	A	G	11: 8,469,564 (GRCm39)	C244R	probably damaging	Het
Vmn2r44	T	A	7: 8,380,879 (GRCm39)	Q338L	possibly damaging	Het
Wdr70	C	T	15: 8,006,463 (GRCm39)	D363N	possibly damaging	Het
Yipf7	A	T	5: 69,698,434 (GRCm39)	S24R	probably benign	Het

Other mutations in Vmn2r2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00326:Vmn2r2	APN	3	64,041,319 (GRCm39)	splice site	probably benign
IGL00980:Vmn2r2	APN	3	64,024,601 (GRCm39)	missense	probably benign	0.11
IGL01389:Vmn2r2	APN	3	64,024,430 (GRCm39)	missense	probably damaging	0.97
IGL01804:Vmn2r2	APN	3	64,041,677 (GRCm39)	missense	possibly damaging	0.91
IGL02750:Vmn2r2	APN	3	64,024,823 (GRCm39)	missense	probably damaging	1.00
IGL03036:Vmn2r2	APN	3	64,024,321 (GRCm39)	missense	probably benign	0.01
IGL03174:Vmn2r2	APN	3	64,024,544 (GRCm39)	nonsense	probably null
PIT4151001:Vmn2r2	UTSW	3	64,024,334 (GRCm39)	missense	possibly damaging	0.67
R0029:Vmn2r2	UTSW	3	64,024,365 (GRCm39)	missense	probably benign	0.00
R0310:Vmn2r2	UTSW	3	64,042,039 (GRCm39)	missense	probably damaging	1.00
R0357:Vmn2r2	UTSW	3	64,041,320 (GRCm39)	splice site	probably null
R0637:Vmn2r2	UTSW	3	64,033,999 (GRCm39)	missense	probably benign	0.00
R1626:Vmn2r2	UTSW	3	64,041,921 (GRCm39)	missense	possibly damaging	0.61
R1662:Vmn2r2	UTSW	3	64,024,551 (GRCm39)	missense	probably benign	0.00
R1710:Vmn2r2	UTSW	3	64,024,820 (GRCm39)	missense	probably benign	0.19
R1797:Vmn2r2	UTSW	3	64,042,128 (GRCm39)	missense	probably benign	0.00
R1862:Vmn2r2	UTSW	3	64,041,942 (GRCm39)	missense	possibly damaging	0.79
R1971:Vmn2r2	UTSW	3	64,034,121 (GRCm39)	missense	probably damaging	1.00
R2051:Vmn2r2	UTSW	3	64,024,766 (GRCm39)	missense	possibly damaging	0.77
R2099:Vmn2r2	UTSW	3	64,024,474 (GRCm39)	missense	probably damaging	1.00
R2275:Vmn2r2	UTSW	3	64,023,930 (GRCm39)	missense	probably benign	0.00
R3078:Vmn2r2	UTSW	3	64,042,053 (GRCm39)	missense	probably benign	0.22
R3418:Vmn2r2	UTSW	3	64,024,320 (GRCm39)	missense	probably benign	0.00
R3419:Vmn2r2	UTSW	3	64,024,320 (GRCm39)	missense	probably benign	0.00
R3959:Vmn2r2	UTSW	3	64,047,947 (GRCm39)	missense	probably benign
R4230:Vmn2r2	UTSW	3	64,041,912 (GRCm39)	missense	probably benign	0.00
R4258:Vmn2r2	UTSW	3	64,042,118 (GRCm39)	missense	probably damaging	1.00
R4810:Vmn2r2	UTSW	3	64,044,883 (GRCm39)	missense	probably damaging	1.00
R4822:Vmn2r2	UTSW	3	64,041,960 (GRCm39)	missense	probably damaging	0.99
R4919:Vmn2r2	UTSW	3	64,024,578 (GRCm39)	missense	possibly damaging	0.56
R4925:Vmn2r2	UTSW	3	64,044,892 (GRCm39)	start codon destroyed	probably null	0.03
R4954:Vmn2r2	UTSW	3	64,047,905 (GRCm39)	missense	probably benign	0.00
R5071:Vmn2r2	UTSW	3	64,024,321 (GRCm39)	missense	probably benign	0.01
R5315:Vmn2r2	UTSW	3	64,024,377 (GRCm39)	missense	probably benign	0.37
R5450:Vmn2r2	UTSW	3	64,034,011 (GRCm39)	missense	probably benign
R5577:Vmn2r2	UTSW	3	64,024,416 (GRCm39)	missense	probably benign	0.00
R5595:Vmn2r2	UTSW	3	64,034,036 (GRCm39)	missense	possibly damaging	0.74
R5727:Vmn2r2	UTSW	3	64,024,608 (GRCm39)	missense	probably benign	0.41
R5810:Vmn2r2	UTSW	3	64,024,815 (GRCm39)	missense	probably damaging	1.00
R5919:Vmn2r2	UTSW	3	64,044,723 (GRCm39)	missense	probably benign	0.39
R6052:Vmn2r2	UTSW	3	64,024,782 (GRCm39)	missense	possibly damaging	0.56
R6084:Vmn2r2	UTSW	3	64,024,467 (GRCm39)	missense	probably benign	0.01
R6299:Vmn2r2	UTSW	3	64,024,074 (GRCm39)	nonsense	probably null
R6762:Vmn2r2	UTSW	3	64,041,870 (GRCm39)	missense	probably damaging	1.00
R6858:Vmn2r2	UTSW	3	64,044,915 (GRCm39)	missense	probably damaging	1.00
R6889:Vmn2r2	UTSW	3	64,024,688 (GRCm39)	missense	probably damaging	0.99
R6990:Vmn2r2	UTSW	3	64,024,608 (GRCm39)	missense	probably benign	0.02
R7195:Vmn2r2	UTSW	3	64,023,900 (GRCm39)	missense	probably benign	0.01
R7269:Vmn2r2	UTSW	3	64,033,998 (GRCm39)	missense	probably benign	0.32
R7699:Vmn2r2	UTSW	3	64,024,536 (GRCm39)	missense	possibly damaging	0.69
R7717:Vmn2r2	UTSW	3	64,042,019 (GRCm39)	missense	possibly damaging	0.95
R7798:Vmn2r2	UTSW	3	64,041,518 (GRCm39)	missense	possibly damaging	0.60
R7914:Vmn2r2	UTSW	3	64,041,526 (GRCm39)	missense	probably benign	0.20
R7974:Vmn2r2	UTSW	3	64,024,808 (GRCm39)	missense	probably damaging	0.99
R8394:Vmn2r2	UTSW	3	64,044,858 (GRCm39)	missense	probably damaging	1.00
R8478:Vmn2r2	UTSW	3	64,024,257 (GRCm39)	missense	possibly damaging	0.87
R8731:Vmn2r2	UTSW	3	64,024,404 (GRCm39)	missense	probably benign	0.16
R9035:Vmn2r2	UTSW	3	64,024,172 (GRCm39)	missense	probably damaging	1.00
R9182:Vmn2r2	UTSW	3	64,044,802 (GRCm39)	missense	probably damaging	1.00
R9225:Vmn2r2	UTSW	3	64,034,021 (GRCm39)	missense	probably benign	0.00
R9266:Vmn2r2	UTSW	3	64,024,057 (GRCm39)	missense	probably damaging	0.98
R9427:Vmn2r2	UTSW	3	64,041,945 (GRCm39)	missense	probably damaging	1.00
R9659:Vmn2r2	UTSW	3	64,041,942 (GRCm39)	missense	possibly damaging	0.79
R9666:Vmn2r2	UTSW	3	64,023,870 (GRCm39)	missense	probably benign	0.08
R9771:Vmn2r2	UTSW	3	64,042,079 (GRCm39)	missense	possibly damaging	0.88
R9788:Vmn2r2	UTSW	3	64,041,942 (GRCm39)	missense	possibly damaging	0.79
X0024:Vmn2r2	UTSW	3	64,044,707 (GRCm39)	nonsense	probably null

Posted On

2015-12-18