Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02851:Vmn2r44'

361903

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r44

Ensembl Gene

ENSMUSG00000094098

Gene Name

vomeronasal 2, receptor 44

Synonyms

EG434113

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL02851

Quality Score

Status

Chromosome

Chromosomal Location

8370459-8386237 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 8386050 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Glutamine at position 63 (L63Q)

Ref Sequence

ENSEMBL: ENSMUSP00000132467 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166499]

AlphaFold

L7N2E1

Predicted Effect

probably damaging
Transcript: ENSMUST00000166499
AA Change: L63Q

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000132467
Gene: ENSMUSG00000094098
AA Change: L63Q

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	469	2.5e-34	PFAM
Pfam:NCD3G	512	565	3.8e-20	PFAM
Pfam:7tm_3	598	833	5.7e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akt1	T	C	12: 112,623,518 (GRCm39)	E314G	probably damaging	Het
Amtn	C	A	5: 88,529,481 (GRCm39)	Q106K	probably benign	Het
Birc6	T	C	17: 74,916,184 (GRCm39)	F1700S	probably damaging	Het
Brdt	T	C	5: 107,525,861 (GRCm39)	S905P	possibly damaging	Het
Ccdc68	C	T	18: 70,080,236 (GRCm39)	Q194*	probably null	Het
Cdc27	A	G	11: 104,417,807 (GRCm39)		probably benign	Het
Cdh13	A	G	8: 119,401,897 (GRCm39)	T100A	probably benign	Het
Cdsn	A	G	17: 35,866,791 (GRCm39)	H440R	possibly damaging	Het
Cenpf	C	A	1: 189,390,227 (GRCm39)	D1202Y	probably damaging	Het
Chat	C	A	14: 32,180,570 (GRCm39)	V21L	probably benign	Het
Clca4c-ps	T	A	3: 144,585,493 (GRCm39)		noncoding transcript	Het
Cst9	A	G	2: 148,677,203 (GRCm39)	I25V	probably benign	Het
Dennd1b	C	A	1: 139,096,705 (GRCm39)		probably benign	Het
Dnah9	A	G	11: 65,928,570 (GRCm39)		probably benign	Het
Dpp3	T	G	19: 4,973,159 (GRCm39)	Q145P	probably benign	Het
Elovl5	C	T	9: 77,888,784 (GRCm39)	T217M	probably damaging	Het
Etl4	T	C	2: 20,812,840 (GRCm39)	V906A	possibly damaging	Het
Gm10647	C	T	9: 66,705,543 (GRCm39)		probably benign	Het
Grm5	A	G	7: 87,723,918 (GRCm39)	N736S	probably damaging	Het
Hectd1	A	G	12: 51,814,423 (GRCm39)	S1638P	possibly damaging	Het
Hsd3b2	T	G	3: 98,623,740 (GRCm39)	E46A	possibly damaging	Het
Igkv15-103	A	G	6: 68,414,674 (GRCm39)	T38A	probably benign	Het
Itpr2	C	A	6: 146,287,477 (GRCm39)	V450L	probably damaging	Het
Kbtbd12	T	C	6: 88,595,311 (GRCm39)	H173R	probably benign	Het
Man1a	G	A	10: 53,795,340 (GRCm39)	R638W	probably damaging	Het
Mterf2	A	T	10: 84,955,878 (GRCm39)	S249T	probably damaging	Het
Muc6	T	C	7: 141,234,627 (GRCm39)	D700G	probably damaging	Het
Myh13	A	G	11: 67,239,742 (GRCm39)	H764R	possibly damaging	Het
Myh7b	A	G	2: 155,470,747 (GRCm39)	D1065G	probably damaging	Het
Naip1	C	A	13: 100,569,770 (GRCm39)	W288L	probably damaging	Het
Naip6	C	A	13: 100,437,168 (GRCm39)	A452S	probably benign	Het
Nop2	A	C	6: 125,121,048 (GRCm39)	K610T	possibly damaging	Het
Nop2	G	T	6: 125,121,033 (GRCm39)	G605V	probably benign	Het
Npvf	G	A	6: 50,629,670 (GRCm39)	R107W	probably benign	Het
Or10h28	T	A	17: 33,488,328 (GRCm39)	I210K	probably benign	Het
Or2h2	T	C	17: 37,397,048 (GRCm39)		probably null	Het
Os9	G	A	10: 126,935,262 (GRCm39)		probably benign	Het
Parp4	T	C	14: 56,886,326 (GRCm39)	S1802P	unknown	Het
Piezo2	G	A	18: 63,153,704 (GRCm39)	S2547F	probably benign	Het
Plekha7	G	T	7: 115,734,413 (GRCm39)	A1024E	probably damaging	Het
R3hdm1	T	C	1: 128,102,677 (GRCm39)		probably benign	Het
Robo4	T	C	9: 37,324,678 (GRCm39)	S1022P	probably damaging	Het
Sc5d	T	C	9: 42,166,690 (GRCm39)	N283S	probably benign	Het
Scn10a	C	T	9: 119,500,674 (GRCm39)	V202M	probably damaging	Het
Slco1a8	C	T	6: 141,949,197 (GRCm39)	G60R	probably damaging	Het
Spag16	T	C	1: 70,304,067 (GRCm39)	I366T	possibly damaging	Het
Sptbn4	G	A	7: 27,126,258 (GRCm39)	R222C	possibly damaging	Het
Tlr9	C	T	9: 106,101,929 (GRCm39)	Q407*	probably null	Het
Trappc12	G	A	12: 28,741,405 (GRCm39)	S768L	probably damaging	Het
Zfy2	C	T	Y: 2,106,894 (GRCm39)	G580D	probably benign	Het
Zfy2	T	A	Y: 2,117,188 (GRCm39)	H213L	probably benign	Het

Other mutations in Vmn2r44

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01650:Vmn2r44	APN	7	8,383,103 (GRCm39)	critical splice donor site	probably null
IGL01723:Vmn2r44	APN	7	8,380,915 (GRCm39)	missense	probably damaging	0.97
IGL01767:Vmn2r44	APN	7	8,383,237 (GRCm39)	missense	probably benign	0.00
IGL02161:Vmn2r44	APN	7	8,380,814 (GRCm39)	missense	possibly damaging	0.94
IGL02299:Vmn2r44	APN	7	8,380,815 (GRCm39)	missense	probably benign
IGL02418:Vmn2r44	APN	7	8,380,864 (GRCm39)	missense	probably damaging	1.00
IGL02829:Vmn2r44	APN	7	8,380,879 (GRCm39)	missense	possibly damaging	0.94
IGL03080:Vmn2r44	APN	7	8,386,244 (GRCm39)	utr 5 prime	probably benign
R1471:Vmn2r44	UTSW	7	8,380,882 (GRCm39)	missense	probably damaging	0.99
R1789:Vmn2r44	UTSW	7	8,383,122 (GRCm39)	missense	possibly damaging	0.64
R1932:Vmn2r44	UTSW	7	8,370,981 (GRCm39)	missense	probably benign	0.04
R2354:Vmn2r44	UTSW	7	8,373,639 (GRCm39)	missense	probably damaging	0.99
R4009:Vmn2r44	UTSW	7	8,380,987 (GRCm39)	missense	possibly damaging	0.82
R4130:Vmn2r44	UTSW	7	8,370,918 (GRCm39)	missense	probably damaging	1.00
R4790:Vmn2r44	UTSW	7	8,370,949 (GRCm39)	missense	probably damaging	1.00
R4854:Vmn2r44	UTSW	7	8,383,300 (GRCm39)	missense	possibly damaging	0.94
R4887:Vmn2r44	UTSW	7	8,380,985 (GRCm39)	missense	probably benign	0.19
R4888:Vmn2r44	UTSW	7	8,380,985 (GRCm39)	missense	probably benign	0.19
R5484:Vmn2r44	UTSW	7	8,383,123 (GRCm39)	missense	possibly damaging	0.69
R6110:Vmn2r44	UTSW	7	8,381,005 (GRCm39)	missense	probably damaging	1.00
R6357:Vmn2r44	UTSW	7	8,373,657 (GRCm39)	missense	probably benign	0.01
R6526:Vmn2r44	UTSW	7	8,381,098 (GRCm39)	missense	probably benign	0.01
R7083:Vmn2r44	UTSW	7	8,381,369 (GRCm39)	missense	probably benign	0.44
R7087:Vmn2r44	UTSW	7	8,381,366 (GRCm39)	missense	probably benign	0.02
R7115:Vmn2r44	UTSW	7	8,370,527 (GRCm39)	nonsense	probably null
R7125:Vmn2r44	UTSW	7	8,370,941 (GRCm39)	missense	probably damaging	1.00
R7258:Vmn2r44	UTSW	7	8,380,848 (GRCm39)	missense	probably damaging	1.00
R7359:Vmn2r44	UTSW	7	8,370,538 (GRCm39)	missense	probably benign	0.30
R7494:Vmn2r44	UTSW	7	8,386,122 (GRCm39)	nonsense	probably null
R7766:Vmn2r44	UTSW	7	8,371,219 (GRCm39)	missense	probably damaging	1.00
R7777:Vmn2r44	UTSW	7	8,381,314 (GRCm39)	missense	possibly damaging	0.81
R8184:Vmn2r44	UTSW	7	8,371,227 (GRCm39)	nonsense	probably null
R8674:Vmn2r44	UTSW	7	8,380,822 (GRCm39)	missense	probably damaging	1.00
R8752:Vmn2r44	UTSW	7	8,370,805 (GRCm39)	missense	probably damaging	1.00
R8897:Vmn2r44	UTSW	7	8,381,242 (GRCm39)	missense	probably damaging	1.00
R8915:Vmn2r44	UTSW	7	8,370,650 (GRCm39)	missense	probably damaging	1.00
R8928:Vmn2r44	UTSW	7	8,381,101 (GRCm39)	missense	probably damaging	1.00
R9163:Vmn2r44	UTSW	7	8,371,091 (GRCm39)	missense	probably benign	0.00
Z1177:Vmn2r44	UTSW	7	8,370,976 (GRCm39)	missense	probably damaging	0.99

Posted On

2015-12-18