Incidental Mutation 'IGL02869:Myo18a'
| ID |
362504 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Myo18a
|
| Ensembl Gene |
ENSMUSG00000000631 |
| Gene Name |
myosin XVIIIA |
| Synonyms |
MyoPDZ |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
IGL02869
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
11 |
| Chromosomal Location |
77654072-77756806 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
C to T
at 77720699 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000129098
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000000645]
[ENSMUST00000092884]
[ENSMUST00000092887]
[ENSMUST00000100794]
[ENSMUST00000102488]
[ENSMUST00000108375]
[ENSMUST00000108376]
[ENSMUST00000130627]
[ENSMUST00000172303]
[ENSMUST00000164334]
[ENSMUST00000168348]
[ENSMUST00000130305]
[ENSMUST00000167856]
[ENSMUST00000169105]
|
| AlphaFold |
Q9JMH9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000000645
|
| SMART Domains |
Protein: ENSMUSP00000000645
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
399 |
1183 |
1.53e-45 |
SMART |
|
IQ
|
1184 |
1206 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
1219 |
1867 |
1.7e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092884
|
| SMART Domains |
Protein: ENSMUSP00000090560
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
68 |
851 |
4.16e-47 |
SMART |
|
IQ
|
852 |
874 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
888 |
1534 |
2e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092887
|
| SMART Domains |
Protein: ENSMUSP00000090563
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
399 |
1182 |
4.16e-47 |
SMART |
|
IQ
|
1183 |
1205 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
1218 |
1866 |
3e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100794
|
| SMART Domains |
Protein: ENSMUSP00000098358
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
68 |
847 |
1.45e-46 |
SMART |
|
IQ
|
848 |
870 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
884 |
1530 |
4.9e-35 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102488
|
| SMART Domains |
Protein: ENSMUSP00000099546
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
399 |
1182 |
4.16e-47 |
SMART |
|
IQ
|
1183 |
1205 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
1218 |
1866 |
3e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108375
|
| SMART Domains |
Protein: ENSMUSP00000104012
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
399 |
1182 |
4.16e-47 |
SMART |
|
IQ
|
1183 |
1205 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
1218 |
1838 |
6.8e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108376
|
| SMART Domains |
Protein: ENSMUSP00000104013
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
399 |
1182 |
4.16e-47 |
SMART |
|
IQ
|
1183 |
1205 |
1.11e-3 |
SMART |
|
Blast:MYSc
|
1258 |
1387 |
1e-14 |
BLAST |
|
low complexity region
|
1396 |
1407 |
N/A |
INTRINSIC |
|
low complexity region
|
1743 |
1762 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130627
|
| SMART Domains |
Protein: ENSMUSP00000119839
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
411 |
1194 |
4.16e-47 |
SMART |
|
IQ
|
1195 |
1217 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
1230 |
1850 |
6.9e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172303
|
| SMART Domains |
Protein: ENSMUSP00000129098
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
80 |
863 |
4.16e-47 |
SMART |
|
IQ
|
864 |
886 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
902 |
1547 |
2.6e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164334
|
| SMART Domains |
Protein: ENSMUSP00000131771
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
68 |
851 |
4.16e-47 |
SMART |
|
IQ
|
852 |
874 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
888 |
1505 |
4e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168348
|
| SMART Domains |
Protein: ENSMUSP00000130696
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
447 |
1230 |
4.16e-47 |
SMART |
|
IQ
|
1231 |
1253 |
1.11e-3 |
SMART |
|
Blast:MYSc
|
1306 |
1435 |
1e-14 |
BLAST |
|
low complexity region
|
1444 |
1455 |
N/A |
INTRINSIC |
|
low complexity region
|
1828 |
1847 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130305
|
| SMART Domains |
Protein: ENSMUSP00000119574
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
80 |
863 |
4.16e-47 |
SMART |
|
IQ
|
864 |
886 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
902 |
1547 |
2.6e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167856
|
| SMART Domains |
Protein: ENSMUSP00000128487
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
16 |
789 |
1.3e-32 |
SMART |
|
IQ
|
790 |
812 |
1.11e-3 |
SMART |
|
Blast:MYSc
|
865 |
994 |
1e-14 |
BLAST |
|
low complexity region
|
1003 |
1014 |
N/A |
INTRINSIC |
|
low complexity region
|
1387 |
1406 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1569 |
1627 |
2.13e-5 |
PROSPERO |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169105
|
| SMART Domains |
Protein: ENSMUSP00000132149
Gene: ENSMUSG00000000631
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
227 |
N/A |
INTRINSIC |
|
PDZ
|
229 |
311 |
5.72e-10 |
SMART |
|
MYSc
|
411 |
1194 |
4.16e-47 |
SMART |
|
IQ
|
1195 |
1217 |
1.11e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
1230 |
1878 |
7.3e-35 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154892
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
A |
16: 4,685,323 (GRCm39) |
S1142T |
possibly damaging |
Het |
| Aadacl4fm5 |
T |
C |
4: 144,512,938 (GRCm39) |
I54V |
probably benign |
Het |
| Actr3b |
T |
G |
5: 26,037,433 (GRCm39) |
V215G |
probably damaging |
Het |
| Adam9 |
C |
T |
8: 25,460,634 (GRCm39) |
V617M |
probably damaging |
Het |
| Adgrl2 |
G |
T |
3: 148,596,241 (GRCm39) |
P32T |
probably damaging |
Het |
| Afg2a |
G |
T |
3: 37,518,694 (GRCm39) |
G743W |
probably damaging |
Het |
| Ago3 |
A |
T |
4: 126,261,580 (GRCm39) |
|
probably benign |
Het |
| Allc |
A |
C |
12: 28,623,206 (GRCm39) |
I20M |
probably benign |
Het |
| Asic3 |
G |
A |
5: 24,621,972 (GRCm39) |
W361* |
probably null |
Het |
| Atf7ip |
A |
G |
6: 136,583,577 (GRCm39) |
K1203E |
probably damaging |
Het |
| Babam2 |
C |
A |
5: 32,162,116 (GRCm39) |
H272Q |
possibly damaging |
Het |
| Baz2b |
G |
A |
2: 59,807,872 (GRCm39) |
T129I |
probably benign |
Het |
| C130073F10Rik |
A |
T |
4: 101,747,590 (GRCm39) |
Y146* |
probably null |
Het |
| Cd247 |
A |
G |
1: 165,684,986 (GRCm39) |
E74G |
probably damaging |
Het |
| Cdh17 |
A |
T |
4: 11,814,908 (GRCm39) |
Q778L |
probably benign |
Het |
| Ceacam1 |
T |
C |
7: 25,175,966 (GRCm39) |
D76G |
probably benign |
Het |
| Cela3a |
T |
C |
4: 137,131,145 (GRCm39) |
K198E |
probably benign |
Het |
| Cemip2 |
T |
A |
19: 21,789,241 (GRCm39) |
D558E |
probably damaging |
Het |
| Ces2a |
T |
A |
8: 105,465,691 (GRCm39) |
D281E |
probably damaging |
Het |
| Cetn2 |
A |
T |
X: 71,958,527 (GRCm39) |
D116E |
probably damaging |
Het |
| Cracd |
A |
G |
5: 77,006,890 (GRCm39) |
K1084E |
unknown |
Het |
| Ctu2 |
G |
T |
8: 123,205,530 (GRCm39) |
|
probably null |
Het |
| Cybb |
T |
C |
X: 9,308,828 (GRCm39) |
N469D |
probably benign |
Het |
| Cygb |
C |
T |
11: 116,540,749 (GRCm39) |
R79Q |
probably damaging |
Het |
| Cyp2d10 |
C |
T |
15: 82,288,069 (GRCm39) |
V186M |
possibly damaging |
Het |
| Defb29 |
T |
A |
2: 152,380,942 (GRCm39) |
|
probably null |
Het |
| Depdc7 |
T |
G |
2: 104,560,694 (GRCm39) |
Q100P |
probably damaging |
Het |
| Dhx30 |
A |
C |
9: 109,926,251 (GRCm39) |
I91R |
probably damaging |
Het |
| Dnm1l |
T |
A |
16: 16,159,288 (GRCm39) |
K105* |
probably null |
Het |
| Eddm13 |
T |
C |
7: 6,272,898 (GRCm39) |
|
probably benign |
Het |
| Efhc1 |
T |
C |
1: 21,037,567 (GRCm39) |
I248T |
probably damaging |
Het |
| Elapor1 |
A |
G |
3: 108,380,182 (GRCm39) |
I309T |
probably benign |
Het |
| Entpd2 |
A |
G |
2: 25,288,120 (GRCm39) |
T115A |
probably damaging |
Het |
| Epb42 |
G |
T |
2: 120,856,227 (GRCm39) |
A439E |
probably benign |
Het |
| Esm1 |
T |
G |
13: 113,346,618 (GRCm39) |
L81R |
probably damaging |
Het |
| F8 |
T |
C |
X: 74,330,987 (GRCm39) |
S968G |
probably benign |
Het |
| Fam234b |
T |
G |
6: 135,202,201 (GRCm39) |
Y308D |
probably damaging |
Het |
| Fbxo46 |
T |
G |
7: 18,871,139 (GRCm39) |
V586G |
probably damaging |
Het |
| Foxp1 |
C |
A |
6: 98,907,044 (GRCm39) |
|
probably benign |
Het |
| Gm10754 |
A |
T |
10: 97,518,136 (GRCm39) |
|
probably benign |
Het |
| Gm12695 |
A |
C |
4: 96,650,370 (GRCm39) |
|
probably benign |
Het |
| Gm5468 |
T |
C |
15: 25,414,726 (GRCm39) |
|
probably benign |
Het |
| Grhl1 |
T |
C |
12: 24,631,490 (GRCm39) |
S66P |
probably damaging |
Het |
| Gstt3 |
A |
T |
10: 75,612,576 (GRCm39) |
|
probably null |
Het |
| Gtf2i |
A |
G |
5: 134,308,281 (GRCm39) |
|
probably benign |
Het |
| Gzmk |
C |
A |
13: 113,308,560 (GRCm39) |
G175C |
probably damaging |
Het |
| Helz2 |
T |
C |
2: 180,872,939 (GRCm39) |
|
probably benign |
Het |
| Ift20 |
T |
C |
11: 78,430,780 (GRCm39) |
|
probably benign |
Het |
| Intu |
A |
G |
3: 40,642,216 (GRCm39) |
D491G |
probably damaging |
Het |
| Itch |
G |
T |
2: 155,015,853 (GRCm39) |
|
probably null |
Het |
| Itgb5 |
A |
G |
16: 33,665,362 (GRCm39) |
N26S |
possibly damaging |
Het |
| Lama2 |
A |
T |
10: 26,891,534 (GRCm39) |
S2526R |
probably damaging |
Het |
| Lat2 |
A |
G |
5: 134,637,027 (GRCm39) |
I40T |
probably damaging |
Het |
| Lipa |
T |
A |
19: 34,471,397 (GRCm39) |
M393L |
probably benign |
Het |
| Lipa |
G |
T |
19: 34,471,371 (GRCm39) |
|
probably benign |
Het |
| Lpcat1 |
T |
A |
13: 73,632,417 (GRCm39) |
L10H |
probably damaging |
Het |
| Lpcat3 |
T |
C |
6: 124,679,970 (GRCm39) |
Y348H |
possibly damaging |
Het |
| Lrp1b |
A |
T |
2: 40,591,842 (GRCm39) |
N50K |
unknown |
Het |
| Lrrk2 |
T |
A |
15: 91,634,480 (GRCm39) |
Y1415N |
probably damaging |
Het |
| Lsamp |
A |
T |
16: 41,965,078 (GRCm39) |
T312S |
probably benign |
Het |
| Man2a2 |
T |
C |
7: 80,013,689 (GRCm39) |
E454G |
probably benign |
Het |
| Mcm3 |
T |
C |
1: 20,879,063 (GRCm39) |
K570R |
probably damaging |
Het |
| Mctp2 |
C |
A |
7: 71,878,219 (GRCm39) |
|
probably null |
Het |
| Msantd2 |
T |
G |
9: 37,434,796 (GRCm39) |
C345W |
probably damaging |
Het |
| Musk |
T |
C |
4: 58,354,078 (GRCm39) |
I362T |
probably benign |
Het |
| Myh15 |
A |
T |
16: 48,965,767 (GRCm39) |
N1224I |
probably benign |
Het |
| Myrfl |
G |
T |
10: 116,664,909 (GRCm39) |
Q374K |
probably damaging |
Het |
| Ndrg1 |
T |
A |
15: 66,818,346 (GRCm39) |
Q87H |
probably benign |
Het |
| Nol9 |
G |
A |
4: 152,131,030 (GRCm39) |
C351Y |
probably damaging |
Het |
| Nr5a1 |
A |
G |
2: 38,598,141 (GRCm39) |
S219P |
probably benign |
Het |
| Or8b43 |
T |
C |
9: 38,360,489 (GRCm39) |
F107S |
possibly damaging |
Het |
| Or8g28 |
A |
T |
9: 39,169,520 (GRCm39) |
Y149* |
probably null |
Het |
| Pcdhb19 |
A |
G |
18: 37,631,690 (GRCm39) |
D495G |
probably damaging |
Het |
| Pfkm |
A |
G |
15: 98,026,123 (GRCm39) |
M573V |
probably damaging |
Het |
| Plec |
A |
T |
15: 76,065,516 (GRCm39) |
L1586Q |
probably damaging |
Het |
| Prelp |
C |
A |
1: 133,843,005 (GRCm39) |
E47* |
probably null |
Het |
| Rbm33 |
T |
A |
5: 28,615,753 (GRCm39) |
I32N |
probably damaging |
Het |
| Rgs12 |
A |
T |
5: 35,183,227 (GRCm39) |
D310V |
probably damaging |
Het |
| Ripor2 |
A |
C |
13: 24,880,512 (GRCm39) |
H404P |
possibly damaging |
Het |
| Sh3d21 |
T |
C |
4: 126,056,034 (GRCm39) |
E124G |
probably benign |
Het |
| Shroom2 |
C |
T |
X: 151,442,549 (GRCm39) |
S872N |
probably benign |
Het |
| Slc44a5 |
A |
G |
3: 153,956,651 (GRCm39) |
Y301C |
probably damaging |
Het |
| Smap1 |
A |
T |
1: 23,930,995 (GRCm39) |
H66Q |
possibly damaging |
Het |
| Smyd1 |
G |
T |
6: 71,198,007 (GRCm39) |
|
probably benign |
Het |
| Sptbn4 |
T |
A |
7: 27,093,573 (GRCm39) |
|
probably benign |
Het |
| Srsf3-ps |
T |
A |
11: 98,516,146 (GRCm39) |
R76* |
probably null |
Het |
| Stag3 |
A |
G |
5: 138,280,955 (GRCm39) |
K49R |
probably damaging |
Het |
| Stim1 |
C |
A |
7: 101,917,758 (GRCm39) |
A46E |
unknown |
Het |
| Stxbp2 |
A |
T |
8: 3,691,971 (GRCm39) |
I538F |
probably benign |
Het |
| Tbc1d19 |
A |
G |
5: 53,992,559 (GRCm39) |
T114A |
probably benign |
Het |
| Tln2 |
G |
A |
9: 67,128,807 (GRCm39) |
|
probably benign |
Het |
| Trmt10a |
T |
A |
3: 137,857,945 (GRCm39) |
|
probably null |
Het |
| Vwde |
G |
A |
6: 13,187,136 (GRCm39) |
H784Y |
probably damaging |
Het |
| Zfp773 |
T |
C |
7: 7,137,232 (GRCm39) |
T121A |
probably benign |
Het |
|
| Other mutations in Myo18a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Myo18a
|
APN |
11 |
77,738,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00753:Myo18a
|
APN |
11 |
77,715,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01137:Myo18a
|
APN |
11 |
77,718,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01536:Myo18a
|
APN |
11 |
77,711,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01642:Myo18a
|
APN |
11 |
77,755,558 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL01728:Myo18a
|
APN |
11 |
77,668,682 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01780:Myo18a
|
APN |
11 |
77,741,073 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02286:Myo18a
|
APN |
11 |
77,668,811 (GRCm39) |
nonsense |
probably null |
|
|
IGL02350:Myo18a
|
APN |
11 |
77,741,073 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02357:Myo18a
|
APN |
11 |
77,741,073 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02420:Myo18a
|
APN |
11 |
77,709,519 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02643:Myo18a
|
APN |
11 |
77,668,998 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02667:Myo18a
|
APN |
11 |
77,748,678 (GRCm39) |
splice site |
probably benign |
|
|
IGL02869:Myo18a
|
APN |
11 |
77,755,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02962:Myo18a
|
APN |
11 |
77,669,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02963:Myo18a
|
APN |
11 |
77,732,844 (GRCm39) |
splice site |
probably benign |
|
|
IGL03410:Myo18a
|
APN |
11 |
77,738,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03050:Myo18a
|
UTSW |
11 |
77,709,596 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0022:Myo18a
|
UTSW |
11 |
77,734,059 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0064:Myo18a
|
UTSW |
11 |
77,738,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0064:Myo18a
|
UTSW |
11 |
77,738,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0098:Myo18a
|
UTSW |
11 |
77,736,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0322:Myo18a
|
UTSW |
11 |
77,720,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0373:Myo18a
|
UTSW |
11 |
77,711,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0379:Myo18a
|
UTSW |
11 |
77,741,632 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0513:Myo18a
|
UTSW |
11 |
77,702,420 (GRCm39) |
intron |
probably benign |
|
|
R0688:Myo18a
|
UTSW |
11 |
77,714,966 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0734:Myo18a
|
UTSW |
11 |
77,738,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0790:Myo18a
|
UTSW |
11 |
77,731,535 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1099:Myo18a
|
UTSW |
11 |
77,709,727 (GRCm39) |
splice site |
probably null |
|
|
R1103:Myo18a
|
UTSW |
11 |
77,714,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1183:Myo18a
|
UTSW |
11 |
77,748,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1216:Myo18a
|
UTSW |
11 |
77,709,473 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1331:Myo18a
|
UTSW |
11 |
77,732,405 (GRCm39) |
missense |
probably benign |
0.28 |
|
R1479:Myo18a
|
UTSW |
11 |
77,733,020 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1723:Myo18a
|
UTSW |
11 |
77,744,140 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1742:Myo18a
|
UTSW |
11 |
77,732,293 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1796:Myo18a
|
UTSW |
11 |
77,720,170 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1823:Myo18a
|
UTSW |
11 |
77,715,923 (GRCm39) |
splice site |
probably benign |
|
|
R1827:Myo18a
|
UTSW |
11 |
77,709,597 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2033:Myo18a
|
UTSW |
11 |
77,733,925 (GRCm39) |
splice site |
probably null |
|
|
R2043:Myo18a
|
UTSW |
11 |
77,714,189 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2105:Myo18a
|
UTSW |
11 |
77,741,060 (GRCm39) |
missense |
probably benign |
|
|
R2191:Myo18a
|
UTSW |
11 |
77,709,441 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2264:Myo18a
|
UTSW |
11 |
77,710,798 (GRCm39) |
splice site |
probably benign |
|
|
R2370:Myo18a
|
UTSW |
11 |
77,668,596 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3015:Myo18a
|
UTSW |
11 |
77,749,846 (GRCm39) |
intron |
probably benign |
|
|
R3433:Myo18a
|
UTSW |
11 |
77,708,870 (GRCm39) |
splice site |
probably null |
|
|
R3739:Myo18a
|
UTSW |
11 |
77,736,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3825:Myo18a
|
UTSW |
11 |
77,668,292 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4056:Myo18a
|
UTSW |
11 |
77,702,839 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4163:Myo18a
|
UTSW |
11 |
77,720,534 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4184:Myo18a
|
UTSW |
11 |
77,748,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4620:Myo18a
|
UTSW |
11 |
77,708,773 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4628:Myo18a
|
UTSW |
11 |
77,714,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4647:Myo18a
|
UTSW |
11 |
77,708,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4701:Myo18a
|
UTSW |
11 |
77,708,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4729:Myo18a
|
UTSW |
11 |
77,668,511 (GRCm39) |
splice site |
probably null |
|
|
R4731:Myo18a
|
UTSW |
11 |
77,720,585 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4739:Myo18a
|
UTSW |
11 |
77,714,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4814:Myo18a
|
UTSW |
11 |
77,750,062 (GRCm39) |
intron |
probably benign |
|
|
R4889:Myo18a
|
UTSW |
11 |
77,723,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4988:Myo18a
|
UTSW |
11 |
77,736,347 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5172:Myo18a
|
UTSW |
11 |
77,714,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5177:Myo18a
|
UTSW |
11 |
77,755,668 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5394:Myo18a
|
UTSW |
11 |
77,744,176 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5643:Myo18a
|
UTSW |
11 |
77,745,513 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5808:Myo18a
|
UTSW |
11 |
77,720,127 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5871:Myo18a
|
UTSW |
11 |
77,723,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5936:Myo18a
|
UTSW |
11 |
77,709,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6017:Myo18a
|
UTSW |
11 |
77,732,349 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6053:Myo18a
|
UTSW |
11 |
77,709,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6271:Myo18a
|
UTSW |
11 |
77,711,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6486:Myo18a
|
UTSW |
11 |
77,755,648 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6558:Myo18a
|
UTSW |
11 |
77,741,678 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6884:Myo18a
|
UTSW |
11 |
77,709,875 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R6983:Myo18a
|
UTSW |
11 |
77,736,341 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6993:Myo18a
|
UTSW |
11 |
77,749,900 (GRCm39) |
intron |
probably benign |
|
|
R7071:Myo18a
|
UTSW |
11 |
77,714,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7074:Myo18a
|
UTSW |
11 |
77,733,387 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7238:Myo18a
|
UTSW |
11 |
77,733,059 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7328:Myo18a
|
UTSW |
11 |
77,698,737 (GRCm39) |
missense |
|
|
|
R7527:Myo18a
|
UTSW |
11 |
77,734,406 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7598:Myo18a
|
UTSW |
11 |
77,738,172 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7671:Myo18a
|
UTSW |
11 |
77,750,246 (GRCm39) |
missense |
|
|
|
R7958:Myo18a
|
UTSW |
11 |
77,732,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8098:Myo18a
|
UTSW |
11 |
77,736,227 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8168:Myo18a
|
UTSW |
11 |
77,711,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8318:Myo18a
|
UTSW |
11 |
77,714,215 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8685:Myo18a
|
UTSW |
11 |
77,745,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8778:Myo18a
|
UTSW |
11 |
77,714,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9023:Myo18a
|
UTSW |
11 |
77,718,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9059:Myo18a
|
UTSW |
11 |
77,668,899 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9186:Myo18a
|
UTSW |
11 |
77,749,847 (GRCm39) |
missense |
|
|
|
R9321:Myo18a
|
UTSW |
11 |
77,733,370 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9357:Myo18a
|
UTSW |
11 |
77,733,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9407:Myo18a
|
UTSW |
11 |
77,709,596 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9430:Myo18a
|
UTSW |
11 |
77,709,410 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9576:Myo18a
|
UTSW |
11 |
77,709,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9585:Myo18a
|
UTSW |
11 |
77,709,495 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9698:Myo18a
|
UTSW |
11 |
77,720,681 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9743:Myo18a
|
UTSW |
11 |
77,723,304 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9777:Myo18a
|
UTSW |
11 |
77,733,080 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Y5407:Myo18a
|
UTSW |
11 |
77,668,641 (GRCm39) |
missense |
probably benign |
0.44 |
|
Z1177:Myo18a
|
UTSW |
11 |
77,732,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1187:Myo18a
|
UTSW |
11 |
77,744,643 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
| Posted On |
2015-12-18 |
Incidental Mutation