Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02879:Serinc3'

362760

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Serinc3

Ensembl Gene

ENSMUSG00000017707

Gene Name

serine incorporator 3

Synonyms

DIFF33, TMS-1, Tde1, AIGP1

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02879

Quality Score

Status

Chromosome

Chromosomal Location

163466577-163487767 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 163474172 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000017851 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000017851]

AlphaFold

Q9QZI9

Predicted Effect

probably benign
Transcript: ENSMUST00000017851

SMART Domains

Protein: ENSMUSP00000017851
Gene: ENSMUSG00000017707

Domain	Start	End	E-Value	Type
Pfam:Serinc	16	470	9e-168	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000129854

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrl3	A	G	5: 81,659,966 (GRCm39)	Y245C	probably damaging	Het
Asb3	G	A	11: 31,051,067 (GRCm39)	R507H	probably damaging	Het
Cacna1g	A	C	11: 94,300,431 (GRCm39)	I2118S	probably benign	Het
Col3a1	A	T	1: 45,380,119 (GRCm39)		probably benign	Het
Ecscr	T	C	18: 35,846,731 (GRCm39)	N221S	possibly damaging	Het
Enpp4	T	C	17: 44,412,841 (GRCm39)	D231G	probably benign	Het
Fastkd5	A	G	2: 130,456,341 (GRCm39)	Y750H	probably damaging	Het
Gm42688	A	G	6: 83,084,125 (GRCm39)	Y510C	probably damaging	Het
Gtse1	T	C	15: 85,753,264 (GRCm39)		probably benign	Het
Il4ra	A	G	7: 125,176,069 (GRCm39)	E759G	possibly damaging	Het
Itgb4	A	G	11: 115,885,178 (GRCm39)	D1019G	probably benign	Het
Kcnh1	T	C	1: 191,959,223 (GRCm39)	V259A	probably damaging	Het
Ksr1	G	A	11: 78,965,270 (GRCm39)	L15F	probably damaging	Het
Lrrc40	G	A	3: 157,747,302 (GRCm39)		probably benign	Het
Myh15	A	T	16: 48,993,422 (GRCm39)	T1686S	possibly damaging	Het
Neb	A	C	2: 52,146,697 (GRCm39)	L2856V	possibly damaging	Het
Nkapd1	C	T	9: 50,520,671 (GRCm39)		probably null	Het
Pcnx2	A	T	8: 126,498,796 (GRCm39)	C1568S	probably damaging	Het
Pld5	T	A	1: 175,798,157 (GRCm39)	K352I	probably damaging	Het
Prmt3	A	G	7: 49,467,811 (GRCm39)	D339G	probably benign	Het
Ptbp2	A	G	3: 119,534,054 (GRCm39)	Y272H	probably damaging	Het
Ptprb	A	G	10: 116,163,873 (GRCm39)	D847G	probably benign	Het
Rin1	C	T	19: 5,101,383 (GRCm39)	T89I	probably damaging	Het
Runx1t1	T	C	4: 13,889,868 (GRCm39)	I599T	unknown	Het
Slc27a5	C	T	7: 12,728,971 (GRCm39)		probably benign	Het
Terf2	C	T	8: 107,803,329 (GRCm39)	S417N	probably benign	Het
Tyw1	T	C	5: 130,325,612 (GRCm39)	V500A	probably damaging	Het
Upk1b	G	A	16: 38,596,640 (GRCm39)		probably benign	Het
Vmn1r81	C	T	7: 11,994,319 (GRCm39)	M96I	probably benign	Het
Vmn2r11	A	T	5: 109,201,704 (GRCm39)	Y267N	possibly damaging	Het

Other mutations in Serinc3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00569:Serinc3	APN	2	163,469,921 (GRCm39)	missense	probably damaging	1.00
IGL01152:Serinc3	APN	2	163,478,831 (GRCm39)	missense	probably damaging	0.99
IGL02945:Serinc3	APN	2	163,472,836 (GRCm39)	splice site	probably benign
R0783:Serinc3	UTSW	2	163,478,923 (GRCm39)	missense	possibly damaging	0.95
R1181:Serinc3	UTSW	2	163,467,446 (GRCm39)	missense	probably damaging	1.00
R1848:Serinc3	UTSW	2	163,487,409 (GRCm39)	unclassified	probably benign
R4254:Serinc3	UTSW	2	163,478,888 (GRCm39)	missense	probably benign
R6225:Serinc3	UTSW	2	163,469,799 (GRCm39)	missense	probably damaging	1.00
R6271:Serinc3	UTSW	2	163,472,896 (GRCm39)	missense	probably benign	0.15
R6860:Serinc3	UTSW	2	163,476,366 (GRCm39)	missense	probably benign
R6986:Serinc3	UTSW	2	163,469,891 (GRCm39)	missense	probably benign	0.00
R7060:Serinc3	UTSW	2	163,478,879 (GRCm39)	missense	probably benign	0.01
R7618:Serinc3	UTSW	2	163,472,889 (GRCm39)	missense	possibly damaging	0.88
R9223:Serinc3	UTSW	2	163,478,812 (GRCm39)	missense	probably benign	0.26
R9274:Serinc3	UTSW	2	163,468,371 (GRCm39)	missense	probably damaging	1.00
R9766:Serinc3	UTSW	2	163,471,095 (GRCm39)	missense	probably damaging	1.00
T0970:Serinc3	UTSW	2	163,469,835 (GRCm39)	small deletion	probably benign

Posted On

2015-12-18