Incidental Mutation 'IGL02898:V1rd19'
| ID |
363465 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
V1rd19
|
| Ensembl Gene |
ENSMUSG00000092456 |
| Gene Name |
vomeronasal 1 receptor, D19 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.061)
|
| Stock # |
IGL02898
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
23702536-23703453 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 23702854 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Proline
at position 107
(T107P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133284
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000173571]
|
| AlphaFold |
Q3KNP5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000173571
AA Change: T107P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000133284
Gene: ENSMUSG00000092456
AA Change: T107P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
296 |
1e-9 |
PFAM |
|
Pfam:V1R
|
42 |
295 |
5.9e-13 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 32 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl5 |
A |
G |
10: 80,178,065 (GRCm39) |
|
probably benign |
Het |
| Brd3 |
A |
G |
2: 27,349,753 (GRCm39) |
S267P |
possibly damaging |
Het |
| Btaf1 |
A |
G |
19: 36,946,468 (GRCm39) |
T425A |
probably benign |
Het |
| Caskin1 |
A |
T |
17: 24,721,383 (GRCm39) |
E544D |
probably benign |
Het |
| Col20a1 |
C |
T |
2: 180,630,905 (GRCm39) |
Q58* |
probably null |
Het |
| Eif2ak1 |
G |
A |
5: 143,826,270 (GRCm39) |
V428I |
probably damaging |
Het |
| Fez2 |
A |
G |
17: 78,692,184 (GRCm39) |
I345T |
probably benign |
Het |
| Focad |
A |
T |
4: 88,310,234 (GRCm39) |
M1388L |
probably benign |
Het |
| Gfer |
T |
C |
17: 24,914,921 (GRCm39) |
R41G |
probably benign |
Het |
| Gm9956 |
C |
T |
10: 56,621,350 (GRCm39) |
S4L |
unknown |
Het |
| Krtap6-1 |
G |
A |
16: 88,828,643 (GRCm39) |
G13D |
unknown |
Het |
| Megf8 |
A |
G |
7: 25,045,933 (GRCm39) |
E1492G |
possibly damaging |
Het |
| Myh7 |
T |
C |
14: 55,221,197 (GRCm39) |
I909V |
probably damaging |
Het |
| Or11g25 |
T |
A |
14: 50,723,643 (GRCm39) |
S243T |
probably damaging |
Het |
| Or1e21 |
T |
A |
11: 73,344,561 (GRCm39) |
H159L |
probably damaging |
Het |
| Otog |
A |
G |
7: 45,959,562 (GRCm39) |
E717G |
probably damaging |
Het |
| Pik3r4 |
A |
G |
9: 105,527,605 (GRCm39) |
I319M |
probably benign |
Het |
| Piwil4 |
A |
T |
9: 14,617,583 (GRCm39) |
|
probably benign |
Het |
| Plekho1 |
T |
A |
3: 95,899,493 (GRCm39) |
H100L |
probably damaging |
Het |
| Prr30 |
T |
G |
14: 101,435,917 (GRCm39) |
D215A |
probably benign |
Het |
| Prss52 |
C |
T |
14: 64,351,115 (GRCm39) |
A300V |
possibly damaging |
Het |
| Ralgps2 |
C |
A |
1: 156,645,314 (GRCm39) |
K514N |
probably benign |
Het |
| Robo4 |
T |
C |
9: 37,319,472 (GRCm39) |
I463T |
probably damaging |
Het |
| Sars1 |
A |
T |
3: 108,336,579 (GRCm39) |
F268Y |
probably damaging |
Het |
| Sidt1 |
C |
T |
16: 44,102,858 (GRCm39) |
R289Q |
possibly damaging |
Het |
| Slco1a8 |
T |
A |
6: 141,940,023 (GRCm39) |
Y140F |
probably benign |
Het |
| Slco2a1 |
T |
C |
9: 102,956,805 (GRCm39) |
V539A |
probably damaging |
Het |
| Snrnp200 |
A |
G |
2: 127,058,676 (GRCm39) |
|
probably benign |
Het |
| Spag17 |
A |
G |
3: 100,008,702 (GRCm39) |
D1944G |
probably benign |
Het |
| Spata1 |
C |
T |
3: 146,181,094 (GRCm39) |
R288Q |
possibly damaging |
Het |
| Tatdn3 |
T |
C |
1: 190,778,507 (GRCm39) |
*233W |
probably null |
Het |
| Ttc3 |
T |
A |
16: 94,220,285 (GRCm39) |
V536E |
probably damaging |
Het |
|
| Other mutations in V1rd19 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02631:V1rd19
|
APN |
7 |
23,702,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03231:V1rd19
|
APN |
7 |
23,703,328 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0021:V1rd19
|
UTSW |
7 |
23,703,029 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0184:V1rd19
|
UTSW |
7 |
23,702,632 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0391:V1rd19
|
UTSW |
7 |
23,703,010 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1520:V1rd19
|
UTSW |
7 |
23,702,623 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1635:V1rd19
|
UTSW |
7 |
23,702,812 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1861:V1rd19
|
UTSW |
7 |
23,703,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:V1rd19
|
UTSW |
7 |
23,702,632 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2008:V1rd19
|
UTSW |
7 |
23,702,726 (GRCm39) |
nonsense |
probably null |
|
|
R2059:V1rd19
|
UTSW |
7 |
23,703,259 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2098:V1rd19
|
UTSW |
7 |
23,703,160 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3001:V1rd19
|
UTSW |
7 |
23,703,310 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3002:V1rd19
|
UTSW |
7 |
23,703,310 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4271:V1rd19
|
UTSW |
7 |
23,702,839 (GRCm39) |
missense |
probably benign |
0.36 |
|
R5130:V1rd19
|
UTSW |
7 |
23,702,537 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R5169:V1rd19
|
UTSW |
7 |
23,703,209 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5297:V1rd19
|
UTSW |
7 |
23,702,714 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5924:V1rd19
|
UTSW |
7 |
23,703,374 (GRCm39) |
missense |
probably benign |
|
|
R6181:V1rd19
|
UTSW |
7 |
23,702,640 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6540:V1rd19
|
UTSW |
7 |
23,703,056 (GRCm39) |
nonsense |
probably null |
|
|
R7331:V1rd19
|
UTSW |
7 |
23,703,308 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7332:V1rd19
|
UTSW |
7 |
23,702,743 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8338:V1rd19
|
UTSW |
7 |
23,702,674 (GRCm39) |
nonsense |
probably null |
|
|
R8398:V1rd19
|
UTSW |
7 |
23,703,374 (GRCm39) |
nonsense |
probably null |
|
|
R8881:V1rd19
|
UTSW |
7 |
23,703,081 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9536:V1rd19
|
UTSW |
7 |
23,703,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0065:V1rd19
|
UTSW |
7 |
23,702,761 (GRCm39) |
missense |
probably benign |
0.08 |
|
| Posted On |
2015-12-18 |
Incidental Mutation