Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02902:Odr4'

363675

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Odr4

Ensembl Gene

ENSMUSG00000006010

Gene Name

odr4 GPCR localization factor homolog

Synonyms

BC003331, 1810053E15Rik

Accession Numbers

Essential gene?

Probably essential (E-score: 0.783) question?

Stock #

IGL02902

Quality Score

Status

Chromosome

Chromosomal Location

150237056-150268831 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (1 bp from exon)

DNA Base Change (assembly)

C to A at 150260179 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000107544 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000006167] [ENSMUST00000094477] [ENSMUST00000097546] [ENSMUST00000097547] [ENSMUST00000111913]

AlphaFold

Q4PJX1

Predicted Effect

probably null
Transcript: ENSMUST00000006167

SMART Domains

Protein: ENSMUSP00000006167
Gene: ENSMUSG00000006010

Domain	Start	End	E-Value	Type
Pfam:ODR4-like	28	364	1.8e-107	PFAM
transmembrane domain	402	424	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000094477

SMART Domains

Protein: ENSMUSP00000092050
Gene: ENSMUSG00000006010

Domain	Start	End	E-Value	Type
Pfam:ODR4-like	28	383	2.8e-120	PFAM
transmembrane domain	424	446	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000097546

SMART Domains

Protein: ENSMUSP00000095152
Gene: ENSMUSG00000006010

Domain	Start	End	E-Value	Type
Pfam:ODR4-like	28	364	1.8e-107	PFAM
transmembrane domain	402	424	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000097547

SMART Domains

Protein: ENSMUSP00000095153
Gene: ENSMUSG00000006010

Domain	Start	End	E-Value	Type
Pfam:ODR4-like	28	209	1.2e-57	PFAM
Pfam:ODR4-like	206	354	3.1e-43	PFAM
transmembrane domain	392	414	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000111913

SMART Domains

Protein: ENSMUSP00000107544
Gene: ENSMUSG00000006010

Domain	Start	End	E-Value	Type
Pfam:ODR4-like	28	386	7.1e-113	PFAM
transmembrane domain	424	446	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000132809

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140112

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000148389

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150615

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 64 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2810459M11Rik	G	T	1: 85,974,087 (GRCm39)	V135F	possibly damaging	Het
Aatk	T	C	11: 119,902,603 (GRCm39)	T541A	probably benign	Het
Abcc1	T	C	16: 14,240,991 (GRCm39)	L516P	probably damaging	Het
Actl6a	T	A	3: 32,776,791 (GRCm39)	V350E	possibly damaging	Het
Afm	A	G	5: 90,674,222 (GRCm39)	K245E	possibly damaging	Het
Agr3	T	C	12: 35,996,915 (GRCm39)	V63A	probably damaging	Het
Arhgef28	A	T	13: 98,083,383 (GRCm39)	M1162K	probably damaging	Het
Casq2	T	A	3: 101,994,113 (GRCm39)	C53*	probably null	Het
Ccdc181	T	C	1: 164,107,470 (GRCm39)	V51A	probably benign	Het
Cd101	A	G	3: 100,926,310 (GRCm39)		probably benign	Het
Csdc2	T	C	15: 81,832,801 (GRCm39)	V69A	probably benign	Het
Cyp2c23	A	T	19: 44,009,997 (GRCm39)		probably benign	Het
Dnph1	A	G	17: 46,809,427 (GRCm39)		probably benign	Het
Egf	T	C	3: 129,474,796 (GRCm39)	T1124A	probably benign	Het
Gpr45	A	G	1: 43,072,371 (GRCm39)	E338G	possibly damaging	Het
Grb14	A	C	2: 64,768,762 (GRCm39)	L98R	probably damaging	Het
Gucy1a1	T	C	3: 82,026,224 (GRCm39)	S77G	possibly damaging	Het
Helb	A	G	10: 119,925,390 (GRCm39)	S996P	probably benign	Het
Huwe1	A	G	X: 150,669,762 (GRCm39)	E1405G	probably damaging	Het
Ifi47	T	C	11: 48,986,617 (GRCm39)	I128T	probably benign	Het
Ift140	T	A	17: 25,309,736 (GRCm39)	Y1089N	probably damaging	Het
Ift56	A	C	6: 38,402,097 (GRCm39)	S530R	probably benign	Het
Il1r1	A	T	1: 40,341,569 (GRCm39)	H324L	probably benign	Het
Irx1	C	T	13: 72,107,974 (GRCm39)	R236H	probably benign	Het
Itpr3	T	C	17: 27,323,530 (GRCm39)	V1185A	probably benign	Het
Kif19a	T	C	11: 114,676,396 (GRCm39)	V450A	possibly damaging	Het
Krtap21-1	G	T	16: 89,200,446 (GRCm39)	Y65*	probably null	Het
Ltn1	A	T	16: 87,176,693 (GRCm39)	N1704K	possibly damaging	Het
Med1	T	C	11: 98,047,335 (GRCm39)		probably benign	Het
Meis2	T	A	2: 115,893,804 (GRCm39)	H36L	probably damaging	Het
Mier2	T	C	10: 79,385,456 (GRCm39)	N124S	probably damaging	Het
Mmp20	A	G	9: 7,654,171 (GRCm39)		probably null	Het
Muc4	A	G	16: 32,569,212 (GRCm39)	T91A	possibly damaging	Het
Myo3b	T	A	2: 70,119,745 (GRCm39)	V935E	probably benign	Het
Ndufa7	T	C	17: 34,048,632 (GRCm39)		probably benign	Het
Nipal1	A	G	5: 72,825,405 (GRCm39)	E366G	possibly damaging	Het
Nobox	A	T	6: 43,282,617 (GRCm39)	N263K	probably benign	Het
Notch2	A	G	3: 98,018,890 (GRCm39)	D684G	probably damaging	Het
Or2t1	A	G	14: 14,328,789 (GRCm38)	H226R	probably benign	Het
Or4c12b	T	A	2: 89,647,508 (GRCm39)	Y273*	probably null	Het
Or5p69	C	A	7: 107,967,336 (GRCm39)	T213K	probably damaging	Het
Or5w13	T	C	2: 87,523,344 (GRCm39)	N294S	probably damaging	Het
Or6aa1	T	C	7: 86,043,743 (GRCm39)		probably benign	Het
Plau	A	C	14: 20,889,965 (GRCm39)	D270A	possibly damaging	Het
Pof1b	T	C	X: 111,558,809 (GRCm39)		probably null	Het
Pramel23	A	G	4: 143,424,913 (GRCm39)	C177R	probably damaging	Het
Prtn3	A	T	10: 79,717,767 (GRCm39)		probably null	Het
Ptges3	T	A	10: 127,904,616 (GRCm39)	D26E	probably benign	Het
Pxmp2	T	C	5: 110,429,160 (GRCm39)	E99G	probably benign	Het
Rasgef1a	A	G	6: 118,060,068 (GRCm39)	R106G	probably benign	Het
Rnf208	T	C	2: 25,133,774 (GRCm39)	V156A	probably benign	Het
Rps6ka1	A	T	4: 133,599,292 (GRCm39)	I45N	possibly damaging	Het
Rps6ka4	C	T	19: 6,809,623 (GRCm39)		probably null	Het
Rsbn1	G	T	3: 103,860,972 (GRCm39)	C466F	possibly damaging	Het
Shkbp1	A	T	7: 27,042,141 (GRCm39)	C605S	probably damaging	Het
Slc2a10	G	A	2: 165,360,142 (GRCm39)	D531N	probably benign	Het
Sox13	A	G	1: 133,317,204 (GRCm39)	L143P	probably damaging	Het
Stx2	C	T	5: 129,069,285 (GRCm39)	R142Q	probably damaging	Het
Tanc1	T	A	2: 59,623,431 (GRCm39)		probably benign	Het
Tubgcp5	C	T	7: 55,456,355 (GRCm39)	Q316*	probably null	Het
Ubc	A	G	5: 125,463,293 (GRCm39)	V678A	probably benign	Het
Unc5d	G	A	8: 29,365,634 (GRCm39)	T117I	probably damaging	Het
Vmn2r4	T	C	3: 64,314,337 (GRCm39)	I126V	probably benign	Het
Zfp410	T	A	12: 84,378,594 (GRCm39)		probably null	Het

Other mutations in Odr4

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01876:Odr4	APN	1	150,258,089 (GRCm39)	missense	probably benign	0.10
IGL02189:Odr4	APN	1	150,247,784 (GRCm39)	missense	possibly damaging	0.94
IGL02257:Odr4	APN	1	150,262,155 (GRCm39)	missense	probably damaging	0.99
IGL02485:Odr4	APN	1	150,239,240 (GRCm39)	critical splice donor site	probably null
IGL02585:Odr4	APN	1	150,239,272 (GRCm39)	missense	probably damaging	0.96
IGL02712:Odr4	APN	1	150,262,107 (GRCm39)	critical splice donor site	probably null
IGL03014:Odr4	APN	1	150,258,804 (GRCm39)	splice site	probably benign
IGL03124:Odr4	APN	1	150,262,176 (GRCm39)	missense	probably benign	0.00
IGL03181:Odr4	APN	1	150,239,290 (GRCm39)	missense	probably benign	0.06
IGL03344:Odr4	APN	1	150,239,295 (GRCm39)	missense	probably damaging	0.99
R1170:Odr4	UTSW	1	150,262,142 (GRCm39)	missense	probably benign	0.00
R1796:Odr4	UTSW	1	150,251,305 (GRCm39)	missense	probably benign
R1902:Odr4	UTSW	1	150,264,360 (GRCm39)	splice site	probably null
R2149:Odr4	UTSW	1	150,264,310 (GRCm39)	missense	probably benign	0.05
R2155:Odr4	UTSW	1	150,258,086 (GRCm39)	missense	possibly damaging	0.68
R2375:Odr4	UTSW	1	150,265,985 (GRCm39)	critical splice donor site	probably null
R3786:Odr4	UTSW	1	150,260,282 (GRCm39)	missense	probably benign	0.21
R3948:Odr4	UTSW	1	150,264,308 (GRCm39)	nonsense	probably null
R4589:Odr4	UTSW	1	150,260,238 (GRCm39)	missense	probably benign	0.11
R4590:Odr4	UTSW	1	150,262,103 (GRCm39)	splice site	probably null
R4815:Odr4	UTSW	1	150,250,597 (GRCm39)	missense	probably damaging	0.99
R5196:Odr4	UTSW	1	150,258,140 (GRCm39)	missense	probably damaging	1.00
R5437:Odr4	UTSW	1	150,239,269 (GRCm39)	missense	probably benign	0.01
R5549:Odr4	UTSW	1	150,247,909 (GRCm39)	missense	possibly damaging	0.86
R5677:Odr4	UTSW	1	150,250,588 (GRCm39)	missense	probably damaging	1.00
R5896:Odr4	UTSW	1	150,256,111 (GRCm39)	missense	probably benign	0.10
R6472:Odr4	UTSW	1	150,257,273 (GRCm39)	missense	probably benign	0.15
R7108:Odr4	UTSW	1	150,258,041 (GRCm39)	missense	probably benign	0.01
R7402:Odr4	UTSW	1	150,262,107 (GRCm39)	critical splice donor site	probably null
R7662:Odr4	UTSW	1	150,258,045 (GRCm39)	missense	probably benign
R7767:Odr4	UTSW	1	150,247,788 (GRCm39)	missense	probably benign	0.00
R7810:Odr4	UTSW	1	150,268,659 (GRCm39)	utr 5 prime	probably benign
R7916:Odr4	UTSW	1	150,260,249 (GRCm39)	missense	probably benign	0.01
R8114:Odr4	UTSW	1	150,264,308 (GRCm39)	nonsense	probably null
R8120:Odr4	UTSW	1	150,260,177 (GRCm39)	splice site	probably null
R8435:Odr4	UTSW	1	150,258,020 (GRCm39)	missense	possibly damaging	0.90
R9397:Odr4	UTSW	1	150,238,616 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-12-18