Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02944:Mageb11'

364659

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mageb11

Ensembl Gene

ENSMUSG00000091497

Gene Name

MAGE family member B11

Synonyms

LOC212952, Gm44

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL02944

Quality Score

Status

Chromosome

Chromosomal Location

89935748-89936740 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 89935868 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Glutamic Acid at position 41 (K41E)

Ref Sequence

ENSEMBL: ENSMUSP00000129722 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000172155]

AlphaFold

G3UW88

Predicted Effect

probably benign
Transcript: ENSMUST00000172155
AA Change: K41E

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000129722
Gene: ENSMUSG00000091497
AA Change: K41E

Domain	Start	End	E-Value	Type
MAGE_N	3	79	1.68e0	SMART
MAGE	98	268	7.16e-91	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akap13	A	G	7: 75,258,405 (GRCm39)	Q343R	probably benign	Het
Antxr1	T	A	6: 87,165,141 (GRCm39)	N432I	possibly damaging	Het
Arhgap15	T	C	2: 44,032,362 (GRCm39)		probably null	Het
Atp6v1h	T	A	1: 5,163,578 (GRCm39)		probably benign	Het
Cav2	T	C	6: 17,281,456 (GRCm39)	Y33H	probably damaging	Het
Ccdc175	T	A	12: 72,164,667 (GRCm39)	D585V	probably benign	Het
Coro7	T	C	16: 4,453,276 (GRCm39)	D271G	probably benign	Het
Cylc1	T	A	X: 110,167,373 (GRCm39)	D551E	possibly damaging	Het
Dnah1	A	T	14: 31,022,828 (GRCm39)	I1103N	possibly damaging	Het
Gmds	T	A	13: 32,522,435 (GRCm39)	Y11F	probably benign	Het
Igkv13-54-1	C	T	6: 69,594,374 (GRCm39)		noncoding transcript	Het
Irf8	A	G	8: 121,481,864 (GRCm39)	T318A	probably benign	Het
Lrrc40	G	A	3: 157,747,302 (GRCm39)		probably benign	Het
Mbd1	G	A	18: 74,410,481 (GRCm39)	G428E	probably damaging	Het
Myom2	A	T	8: 15,154,065 (GRCm39)		probably null	Het
Nav2	C	T	7: 49,070,004 (GRCm39)	R287W	probably damaging	Het
Nfs1	C	T	2: 155,969,688 (GRCm39)	D320N	probably damaging	Het
Nlrp9a	A	T	7: 26,258,076 (GRCm39)	T565S	probably benign	Het
Nod1	A	T	6: 54,901,932 (GRCm39)	I951N	possibly damaging	Het
Or1n1b	T	G	2: 36,780,800 (GRCm39)	E20A	possibly damaging	Het
Or2ag1b	A	G	7: 106,288,476 (GRCm39)	L154P	probably damaging	Het
Or52e8b	A	G	7: 104,674,130 (GRCm39)	L19P	probably damaging	Het
Or8d2	A	T	9: 38,760,048 (GRCm39)	I213F	possibly damaging	Het
Pkhd1l1	T	C	15: 44,364,927 (GRCm39)	Y689H	probably damaging	Het
Ppp2r5c	A	G	12: 110,534,234 (GRCm39)	I366V	probably benign	Het
Ppp3cb	T	C	14: 20,578,303 (GRCm39)	Y149C	probably damaging	Het
Prdm1	T	C	10: 44,317,807 (GRCm39)	S354G	probably benign	Het
Ralgapa1	T	A	12: 55,804,736 (GRCm39)	Q520L	probably benign	Het
Slc25a54	A	T	3: 108,987,931 (GRCm39)	Y24F	probably benign	Het
Slfn3	T	A	11: 83,103,837 (GRCm39)	V236E	probably damaging	Het
Syt6	A	G	3: 103,482,865 (GRCm39)		probably benign	Het
Trim30a	G	T	7: 104,084,984 (GRCm39)	N75K	probably benign	Het
Vmn1r175	T	C	7: 23,508,591 (GRCm39)	E12G	probably damaging	Het
Xylt1	A	T	7: 117,233,984 (GRCm39)	T504S	probably benign	Het

Other mutations in Mageb11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03246:Mageb11	APN	X	89,936,008 (GRCm39)	missense	probably benign	0.00
R1385:Mageb11	UTSW	X	89,935,874 (GRCm39)	missense	probably benign	0.01

Posted On

2015-12-18