Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02965:Tnxb'

365510

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tnxb

Ensembl Gene

ENSMUSG00000033327

Gene Name

tenascin XB

Synonyms

Tnx, TN-MHC

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02965

Quality Score

Status

Chromosome

Chromosomal Location

34879431-34938789 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 34928628 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Asparagine at position 2681 (Y2681N)

Ref Sequence

ENSEMBL: ENSMUSP00000084661 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000087399] [ENSMUST00000168533]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000087399
AA Change: Y2681N

PolyPhen 2 Score 0.931 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000084661
Gene: ENSMUSG00000033327
AA Change: Y2681N

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
low complexity region	33	44	N/A	INTRINSIC
low complexity region	69	89	N/A	INTRINSIC
low complexity region	92	103	N/A	INTRINSIC
EGF	173	201	1.59e1	SMART
EGF	204	232	7.41e0	SMART
EGF	235	263	2.64e1	SMART
EGF	266	294	2.64e1	SMART
EGF	297	325	9.13e0	SMART
EGF	328	356	2.07e1	SMART
EGF_like	359	387	3.16e1	SMART
EGF_like	390	418	4.64e1	SMART
EGF_like	421	449	3.29e1	SMART
EGF_like	452	480	7.09e1	SMART
EGF	483	511	1.15e1	SMART
EGF	514	542	1.91e1	SMART
EGF_like	545	573	4.11e1	SMART
EGF	576	604	7.95e0	SMART
EGF	607	635	1.23e1	SMART
EGF_like	638	666	4.93e1	SMART
EGF_like	674	702	5.24e1	SMART
EGF	705	733	2.29e1	SMART
FN3	736	816	4.12e-3	SMART
FN3	827	904	1.21e-9	SMART
FN3	1047	1126	3.97e-5	SMART
FN3	1142	1223	3.62e-8	SMART
low complexity region	1230	1241	N/A	INTRINSIC
FN3	1242	1320	2.31e-6	SMART
FN3	1351	1431	8.77e-7	SMART
FN3	1460	1539	3.01e-5	SMART
FN3	1556	1636	2.76e-4	SMART
FN3	1657	1736	5.78e-7	SMART
FN3	1752	1832	4.7e-7	SMART
FN3	1851	1929	1.95e-4	SMART
FN3	1955	2034	4.56e-5	SMART
FN3	2066	2145	2.23e-8	SMART
FN3	2164	2244	7.75e-8	SMART
FN3	2279	2358	8.5e-5	SMART
FN3	2387	2467	2.94e-8	SMART
FN3	2501	2580	1.7e-4	SMART
low complexity region	2588	2598	N/A	INTRINSIC
FN3	2607	2687	6.75e-8	SMART
FN3	2716	2795	7.4e-5	SMART
FN3	2822	2902	1.35e-7	SMART
FN3	2931	3010	5.61e-5	SMART
FN3	3026	3106	6.01e-5	SMART
FN3	3120	3199	6.45e-5	SMART
FN3	3214	3293	9.54e-8	SMART
FN3	3316	3396	2.81e-5	SMART
FN3	3416	3502	1.98e-5	SMART
FN3	3518	3596	5.65e-10	SMART
FN3	3607	3682	7.63e-7	SMART
FN3	3695	3770	6.54e-6	SMART
FBG	3787	3997	8.88e-125	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000168533

SMART Domains

Protein: ENSMUSP00000127487
Gene: ENSMUSG00000033327

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
low complexity region	33	44	N/A	INTRINSIC
low complexity region	69	89	N/A	INTRINSIC
low complexity region	92	103	N/A	INTRINSIC
EGF	173	201	1.59e1	SMART
EGF	204	232	7.41e0	SMART
EGF	235	263	2.64e1	SMART
EGF	266	294	2.64e1	SMART
EGF	297	325	9.13e0	SMART
EGF	328	356	2.07e1	SMART
EGF_like	359	387	3.16e1	SMART
EGF_like	390	418	4.64e1	SMART
EGF_like	421	449	3.29e1	SMART
EGF_like	452	480	7.09e1	SMART
EGF	483	511	1.15e1	SMART
EGF	514	542	1.91e1	SMART
EGF_like	545	573	4.11e1	SMART
EGF	576	604	7.95e0	SMART
EGF	607	635	1.23e1	SMART
EGF_like	638	666	4.93e1	SMART
EGF_like	674	702	5.24e1	SMART
EGF	705	733	2.29e1	SMART
FN3	736	816	4.12e-3	SMART
FN3	827	904	1.21e-9	SMART
FN3	924	1003	3.97e-5	SMART
FN3	1019	1100	3.62e-8	SMART
low complexity region	1107	1118	N/A	INTRINSIC
FN3	1119	1197	2.31e-6	SMART
FN3	1228	1308	8.77e-7	SMART
FN3	1337	1416	3.01e-5	SMART
FN3	1433	1513	2.76e-4	SMART
FN3	1534	1613	5.78e-7	SMART
FN3	1629	1709	4.7e-7	SMART
FN3	1728	1806	1.95e-4	SMART
FN3	1832	1911	4.56e-5	SMART
FN3	1943	2022	2.23e-8	SMART
FN3	2051	2130	5.61e-5	SMART
FN3	2146	2226	6.01e-5	SMART
FN3	2240	2319	6.45e-5	SMART
FN3	2334	2413	9.54e-8	SMART
FN3	2436	2516	2.81e-5	SMART
FN3	2536	2622	1.98e-5	SMART
FN3	2638	2716	5.65e-10	SMART
FN3	2727	2802	7.63e-7	SMART
FN3	2815	2890	6.54e-6	SMART
FBG	2907	3117	8.88e-125	SMART

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mice have stretchy skin, similar to patients with human Ehlers-Danlos syndrome. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca6	T	C	11: 110,071,439 (GRCm39)	K1471R	probably benign	Het
Add1	A	G	5: 34,777,467 (GRCm39)	S77G	probably damaging	Het
Atm	G	T	9: 53,364,863 (GRCm39)	N2642K	probably damaging	Het
Atp6v0a2	T	A	5: 124,767,267 (GRCm39)	M10K	possibly damaging	Het
Btd	T	A	14: 31,389,193 (GRCm39)	S305T	probably damaging	Het
Cmya5	C	T	13: 93,229,065 (GRCm39)	V2008I	probably benign	Het
Cpd	T	G	11: 76,681,814 (GRCm39)		probably benign	Het
Dis3l	A	G	9: 64,217,766 (GRCm39)	F772L	probably damaging	Het
Dlg5	A	T	14: 24,222,091 (GRCm39)	I517N	probably damaging	Het
Fig4	G	A	10: 41,161,661 (GRCm39)	T34M	probably damaging	Het
Flna	C	T	X: 73,270,816 (GRCm39)	V2235I	probably damaging	Het
Flot2	T	C	11: 77,950,031 (GRCm39)	I371T	possibly damaging	Het
Fsip2	G	A	2: 82,813,398 (GRCm39)	S3239N	probably benign	Het
Gbp3	A	G	3: 142,273,343 (GRCm39)	I297V	probably benign	Het
Gcnt3	T	C	9: 69,942,235 (GRCm39)	E111G	probably benign	Het
Gdi1	G	T	X: 73,351,331 (GRCm39)	A148S	probably benign	Het
Heatr5b	G	A	17: 79,060,502 (GRCm39)	H2058Y	probably benign	Het
Hsp90aa1	A	G	12: 110,662,113 (GRCm39)	M1T	probably null	Het
Il22b	A	G	10: 118,130,762 (GRCm39)	S45P	probably damaging	Het
Inppl1	C	A	7: 101,477,478 (GRCm39)	V715F	possibly damaging	Het
Kansl1	T	C	11: 104,225,991 (GRCm39)	Y975C	probably damaging	Het
Kif18b	A	G	11: 102,807,338 (GRCm39)		probably benign	Het
Krt40	T	A	11: 99,432,492 (GRCm39)	R175W	probably damaging	Het
Map3k19	T	C	1: 127,751,803 (GRCm39)	D516G	probably damaging	Het
Mfsd3	A	G	15: 76,587,352 (GRCm39)	H345R	probably benign	Het
Mlkl	A	T	8: 112,058,469 (GRCm39)	I162N	probably benign	Het
Mtnr1a	A	T	8: 45,522,419 (GRCm39)	N58I	probably damaging	Het
Nsmf	T	C	2: 24,951,774 (GRCm39)	V499A	probably damaging	Het
Nudt6	A	G	3: 37,473,655 (GRCm39)	L22P	probably damaging	Het
Nxf7	T	G	X: 134,490,159 (GRCm39)	E35A	probably damaging	Het
Or11h23	A	C	14: 50,948,653 (GRCm39)	I289L	probably damaging	Het
Paf1	T	C	7: 28,095,629 (GRCm39)		probably null	Het
Pcdhb11	G	T	18: 37,557,021 (GRCm39)	V784L	probably benign	Het
Pglyrp2	T	C	17: 32,637,560 (GRCm39)	D156G	probably benign	Het
Pnpt1	A	G	11: 29,106,939 (GRCm39)	D670G	probably damaging	Het
Polr1b	T	A	2: 128,967,443 (GRCm39)	H945Q	probably benign	Het
Ptk6	C	T	2: 180,840,861 (GRCm39)		probably benign	Het
Rftn1	C	T	17: 50,362,280 (GRCm39)	E273K	probably benign	Het
Rnf125	A	G	18: 21,116,168 (GRCm39)	I117V	probably benign	Het
Robo4	A	G	9: 37,321,765 (GRCm39)	K742R	possibly damaging	Het
Sez6l	T	C	5: 112,623,440 (GRCm39)	E37G	probably damaging	Het
Skint4	A	T	4: 111,993,218 (GRCm39)	I306L	probably benign	Het
Sntb1	A	T	15: 55,506,081 (GRCm39)	Y497*	probably null	Het
Snx27	C	A	3: 94,489,733 (GRCm39)	V42L	probably damaging	Het
Sorbs1	T	A	19: 40,365,187 (GRCm39)	T199S	probably benign	Het
Sorcs2	A	G	5: 36,235,301 (GRCm39)	Y72H	probably benign	Het
Spef2	G	T	15: 9,725,192 (GRCm39)		probably benign	Het
Sucla2	G	T	14: 73,816,871 (GRCm39)	V204L	probably benign	Het
Tescl	C	A	7: 24,033,098 (GRCm39)	V76F	probably damaging	Het
Usp42	T	C	5: 143,713,769 (GRCm39)	T2A	probably damaging	Het
Vdac3-ps1	T	A	13: 18,205,431 (GRCm39)		noncoding transcript	Het
Wapl	T	A	14: 34,461,181 (GRCm39)		probably benign	Het

Other mutations in Tnxb

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Tnxb	APN	17	34,904,603 (GRCm39)	missense	probably damaging	1.00
IGL00424:Tnxb	APN	17	34,933,666 (GRCm39)	missense	probably damaging	1.00
IGL00486:Tnxb	APN	17	34,911,356 (GRCm39)	missense	probably damaging	1.00
IGL00952:Tnxb	APN	17	34,932,102 (GRCm39)	missense	probably damaging	1.00
IGL00974:Tnxb	APN	17	34,937,707 (GRCm39)	critical splice donor site	probably null
IGL01017:Tnxb	APN	17	34,912,782 (GRCm39)	missense	probably damaging	0.98
IGL01082:Tnxb	APN	17	34,933,584 (GRCm39)	missense	probably damaging	0.97
IGL01397:Tnxb	APN	17	34,933,647 (GRCm39)	missense	probably damaging	0.99
IGL01473:Tnxb	APN	17	34,904,675 (GRCm39)	missense	probably damaging	0.99
IGL01642:Tnxb	APN	17	34,937,488 (GRCm39)	missense	probably damaging	1.00
IGL01774:Tnxb	APN	17	34,907,813 (GRCm39)	missense	probably damaging	1.00
IGL01971:Tnxb	APN	17	34,891,271 (GRCm39)	missense	probably damaging	1.00
IGL02016:Tnxb	APN	17	34,891,249 (GRCm39)	missense	probably damaging	0.98
IGL02160:Tnxb	APN	17	34,933,719 (GRCm39)	missense	probably benign	0.01
IGL02473:Tnxb	APN	17	34,936,736 (GRCm39)	missense	probably damaging	1.00
IGL02666:Tnxb	APN	17	34,903,913 (GRCm39)	missense	probably benign	0.20
IGL02831:Tnxb	APN	17	34,922,545 (GRCm39)	missense	possibly damaging	0.93
IGL02838:Tnxb	APN	17	34,908,606 (GRCm39)	missense	possibly damaging	0.74
IGL03155:Tnxb	APN	17	34,932,569 (GRCm39)	missense	probably damaging	1.00
IGL03194:Tnxb	APN	17	34,914,921 (GRCm39)	nonsense	probably null
IGL03215:Tnxb	APN	17	34,911,499 (GRCm39)	missense	possibly damaging	0.66
IGL03256:Tnxb	APN	17	34,907,694 (GRCm39)	missense	probably damaging	1.00
BB008:Tnxb	UTSW	17	34,907,672 (GRCm39)	missense	probably damaging	1.00
BB018:Tnxb	UTSW	17	34,907,672 (GRCm39)	missense	probably damaging	1.00
E0370:Tnxb	UTSW	17	34,897,917 (GRCm39)	missense	probably damaging	1.00
R0006:Tnxb	UTSW	17	34,901,266 (GRCm39)	missense	probably benign	0.07
R0049:Tnxb	UTSW	17	34,928,542 (GRCm39)	missense	possibly damaging	0.93
R0050:Tnxb	UTSW	17	34,892,299 (GRCm39)	missense	probably damaging	1.00
R0233:Tnxb	UTSW	17	34,918,007 (GRCm39)	missense	probably benign	0.32
R0233:Tnxb	UTSW	17	34,918,007 (GRCm39)	missense	probably benign	0.32
R0311:Tnxb	UTSW	17	34,935,958 (GRCm39)	missense	probably damaging	0.97
R0326:Tnxb	UTSW	17	34,917,153 (GRCm39)	missense	probably benign	0.32
R0387:Tnxb	UTSW	17	34,902,548 (GRCm39)	missense	probably benign	0.30
R0396:Tnxb	UTSW	17	34,890,707 (GRCm39)	missense	probably damaging	1.00
R0511:Tnxb	UTSW	17	34,937,219 (GRCm39)	missense	probably damaging	0.96
R0540:Tnxb	UTSW	17	34,890,892 (GRCm39)	missense	probably damaging	1.00
R0563:Tnxb	UTSW	17	34,935,921 (GRCm39)	missense	probably benign	0.05
R0575:Tnxb	UTSW	17	34,936,180 (GRCm39)	missense	possibly damaging	0.91
R0586:Tnxb	UTSW	17	34,891,118 (GRCm39)	missense	probably damaging	1.00
R0607:Tnxb	UTSW	17	34,890,892 (GRCm39)	missense	probably damaging	1.00
R0622:Tnxb	UTSW	17	34,937,703 (GRCm39)	missense	probably damaging	1.00
R0624:Tnxb	UTSW	17	34,902,522 (GRCm39)	missense	probably damaging	1.00
R0709:Tnxb	UTSW	17	34,908,328 (GRCm39)	missense	probably damaging	1.00
R0898:Tnxb	UTSW	17	34,889,719 (GRCm39)	missense	probably damaging	1.00
R0970:Tnxb	UTSW	17	34,917,917 (GRCm39)	missense	possibly damaging	0.85
R0972:Tnxb	UTSW	17	34,904,117 (GRCm39)	missense	probably damaging	1.00
R1118:Tnxb	UTSW	17	34,904,017 (GRCm39)	missense	probably damaging	1.00
R1119:Tnxb	UTSW	17	34,904,017 (GRCm39)	missense	probably damaging	1.00
R1226:Tnxb	UTSW	17	34,907,903 (GRCm39)	missense	probably damaging	1.00
R1296:Tnxb	UTSW	17	34,890,551 (GRCm39)	missense	probably damaging	1.00
R1297:Tnxb	UTSW	17	34,929,140 (GRCm39)	missense	probably damaging	0.96
R1349:Tnxb	UTSW	17	34,929,267 (GRCm39)	missense	possibly damaging	0.67
R1356:Tnxb	UTSW	17	34,914,446 (GRCm39)	missense	possibly damaging	0.53
R1372:Tnxb	UTSW	17	34,929,267 (GRCm39)	missense	possibly damaging	0.67
R1521:Tnxb	UTSW	17	34,930,477 (GRCm39)	missense	probably damaging	1.00
R1522:Tnxb	UTSW	17	34,937,612 (GRCm39)	missense	probably damaging	1.00
R1532:Tnxb	UTSW	17	34,929,804 (GRCm39)	missense	probably damaging	1.00
R1735:Tnxb	UTSW	17	34,936,944 (GRCm39)	missense	probably damaging	1.00
R1778:Tnxb	UTSW	17	34,902,548 (GRCm39)	missense	probably benign	0.30
R1802:Tnxb	UTSW	17	34,922,863 (GRCm39)	missense	probably damaging	0.98
R1824:Tnxb	UTSW	17	34,911,307 (GRCm39)	nonsense	probably null
R1838:Tnxb	UTSW	17	34,897,884 (GRCm39)	missense	probably damaging	0.96
R1863:Tnxb	UTSW	17	34,889,848 (GRCm39)	missense	probably damaging	1.00
R1865:Tnxb	UTSW	17	34,922,431 (GRCm39)	nonsense	probably null
R1867:Tnxb	UTSW	17	34,890,821 (GRCm39)	missense	probably damaging	1.00
R1883:Tnxb	UTSW	17	34,908,539 (GRCm39)	missense	probably benign	0.01
R1884:Tnxb	UTSW	17	34,908,539 (GRCm39)	missense	probably benign	0.01
R1889:Tnxb	UTSW	17	34,914,799 (GRCm39)	missense	probably damaging	0.97
R1969:Tnxb	UTSW	17	34,898,055 (GRCm39)	missense	probably benign	0.20
R1989:Tnxb	UTSW	17	34,912,859 (GRCm39)	missense	probably damaging	1.00
R1989:Tnxb	UTSW	17	34,902,351 (GRCm39)	missense	probably benign	0.08
R1991:Tnxb	UTSW	17	34,901,225 (GRCm39)	missense	probably damaging	1.00
R1991:Tnxb	UTSW	17	34,890,878 (GRCm39)	missense	probably damaging	1.00
R1992:Tnxb	UTSW	17	34,890,878 (GRCm39)	missense	probably damaging	1.00
R2001:Tnxb	UTSW	17	34,911,553 (GRCm39)	missense	possibly damaging	0.82
R2018:Tnxb	UTSW	17	34,890,724 (GRCm39)	missense	probably benign	0.04
R2030:Tnxb	UTSW	17	34,937,443 (GRCm39)	missense	probably damaging	1.00
R2037:Tnxb	UTSW	17	34,918,179 (GRCm39)	missense	probably damaging	1.00
R2103:Tnxb	UTSW	17	34,901,225 (GRCm39)	missense	probably damaging	1.00
R2116:Tnxb	UTSW	17	34,891,201 (GRCm39)	missense	probably damaging	1.00
R2206:Tnxb	UTSW	17	34,928,391 (GRCm39)	missense	possibly damaging	0.86
R2207:Tnxb	UTSW	17	34,928,391 (GRCm39)	missense	possibly damaging	0.86
R2215:Tnxb	UTSW	17	34,923,114 (GRCm39)	missense	possibly damaging	0.93
R2413:Tnxb	UTSW	17	34,937,252 (GRCm39)	missense	probably damaging	0.99
R2680:Tnxb	UTSW	17	34,922,594 (GRCm39)	missense	possibly damaging	0.51
R2910:Tnxb	UTSW	17	34,891,424 (GRCm39)	missense	probably damaging	1.00
R2984:Tnxb	UTSW	17	34,897,636 (GRCm39)	nonsense	probably null
R3120:Tnxb	UTSW	17	34,911,329 (GRCm39)	missense	possibly damaging	0.86
R3429:Tnxb	UTSW	17	34,922,561 (GRCm39)	missense	probably damaging	0.98
R3429:Tnxb	UTSW	17	34,891,605 (GRCm39)	nonsense	probably null
R3552:Tnxb	UTSW	17	34,937,695 (GRCm39)	missense	probably damaging	1.00
R3698:Tnxb	UTSW	17	34,909,407 (GRCm39)	critical splice donor site	probably null
R3720:Tnxb	UTSW	17	34,931,938 (GRCm39)	missense	possibly damaging	0.95
R3841:Tnxb	UTSW	17	34,917,897 (GRCm39)	missense	possibly damaging	0.72
R3848:Tnxb	UTSW	17	34,909,369 (GRCm39)	missense	possibly damaging	0.82
R3886:Tnxb	UTSW	17	34,937,885 (GRCm39)	missense	probably damaging	1.00
R4074:Tnxb	UTSW	17	34,890,845 (GRCm39)	missense	probably benign	0.22
R4159:Tnxb	UTSW	17	34,930,491 (GRCm39)	missense	probably damaging	0.99
R4160:Tnxb	UTSW	17	34,930,491 (GRCm39)	missense	probably damaging	0.99
R4161:Tnxb	UTSW	17	34,930,491 (GRCm39)	missense	probably damaging	0.99
R4181:Tnxb	UTSW	17	34,928,428 (GRCm39)	missense	possibly damaging	0.93
R4210:Tnxb	UTSW	17	34,929,951 (GRCm39)	missense	possibly damaging	0.84
R4275:Tnxb	UTSW	17	34,917,205 (GRCm39)	missense	probably damaging	0.98
R4329:Tnxb	UTSW	17	34,912,838 (GRCm39)	missense	probably damaging	1.00
R4394:Tnxb	UTSW	17	34,897,636 (GRCm39)	nonsense	probably null
R4395:Tnxb	UTSW	17	34,897,636 (GRCm39)	nonsense	probably null
R4397:Tnxb	UTSW	17	34,897,636 (GRCm39)	nonsense	probably null
R4540:Tnxb	UTSW	17	34,922,309 (GRCm39)	missense	possibly damaging	0.86
R4673:Tnxb	UTSW	17	34,891,514 (GRCm39)	missense	probably damaging	0.99
R4719:Tnxb	UTSW	17	34,908,394 (GRCm39)	missense	probably damaging	1.00
R4725:Tnxb	UTSW	17	34,918,041 (GRCm39)	missense	probably damaging	0.99
R4753:Tnxb	UTSW	17	34,914,909 (GRCm39)	missense	possibly damaging	0.71
R4777:Tnxb	UTSW	17	34,890,917 (GRCm39)	missense	probably damaging	1.00
R4837:Tnxb	UTSW	17	34,936,981 (GRCm39)	missense	probably damaging	0.98
R4898:Tnxb	UTSW	17	34,914,566 (GRCm39)	missense	possibly damaging	0.95
R4938:Tnxb	UTSW	17	34,932,606 (GRCm39)	missense	probably damaging	1.00
R5044:Tnxb	UTSW	17	34,936,457 (GRCm39)	missense	probably damaging	1.00
R5100:Tnxb	UTSW	17	34,929,902 (GRCm39)	missense	probably damaging	0.99
R5223:Tnxb	UTSW	17	34,923,052 (GRCm39)	missense	possibly damaging	0.51
R5269:Tnxb	UTSW	17	34,922,582 (GRCm39)	missense	possibly damaging	0.95
R5333:Tnxb	UTSW	17	34,909,205 (GRCm39)	missense	probably damaging	1.00
R5454:Tnxb	UTSW	17	34,928,599 (GRCm39)	missense	possibly damaging	0.71
R5470:Tnxb	UTSW	17	34,935,947 (GRCm39)	missense	probably null	1.00
R5475:Tnxb	UTSW	17	34,908,567 (GRCm39)	missense	probably damaging	1.00
R5574:Tnxb	UTSW	17	34,929,998 (GRCm39)	missense	probably benign
R5596:Tnxb	UTSW	17	34,907,778 (GRCm39)	missense	probably damaging	1.00
R5599:Tnxb	UTSW	17	34,909,179 (GRCm39)	missense	probably benign	0.22
R5599:Tnxb	UTSW	17	34,909,176 (GRCm39)	missense	probably damaging	1.00
R5615:Tnxb	UTSW	17	34,902,392 (GRCm39)	missense	probably damaging	1.00
R5620:Tnxb	UTSW	17	34,936,504 (GRCm39)	nonsense	probably null
R5625:Tnxb	UTSW	17	34,904,185 (GRCm39)	missense	probably benign	0.30
R5734:Tnxb	UTSW	17	34,917,884 (GRCm39)	missense	possibly damaging	0.53
R5896:Tnxb	UTSW	17	34,891,126 (GRCm39)	missense	probably damaging	1.00
R5961:Tnxb	UTSW	17	34,937,609 (GRCm39)	missense	probably damaging	1.00
R5974:Tnxb	UTSW	17	34,904,681 (GRCm39)	missense	probably damaging	1.00
R6091:Tnxb	UTSW	17	34,929,338 (GRCm39)	missense	probably damaging	0.98
R6134:Tnxb	UTSW	17	34,890,986 (GRCm39)	missense	probably damaging	0.96
R6325:Tnxb	UTSW	17	34,911,398 (GRCm39)	missense	probably damaging	1.00
R6358:Tnxb	UTSW	17	34,897,968 (GRCm39)	missense	probably damaging	0.98
R6362:Tnxb	UTSW	17	34,913,362 (GRCm39)	missense	probably damaging	1.00
R6432:Tnxb	UTSW	17	34,936,891 (GRCm39)	missense	probably damaging	1.00
R6461:Tnxb	UTSW	17	34,890,872 (GRCm39)	missense	probably damaging	1.00
R6467:Tnxb	UTSW	17	34,912,898 (GRCm39)	missense	probably damaging	1.00
R6476:Tnxb	UTSW	17	34,909,166 (GRCm39)	missense	probably damaging	0.98
R6477:Tnxb	UTSW	17	34,938,513 (GRCm39)	missense	probably damaging	1.00
R6631:Tnxb	UTSW	17	34,937,222 (GRCm39)	missense	probably damaging	1.00
R6774:Tnxb	UTSW	17	34,928,606 (GRCm39)	nonsense	probably null
R6787:Tnxb	UTSW	17	34,929,710 (GRCm39)	missense	probably benign	0.02
R6805:Tnxb	UTSW	17	34,917,127 (GRCm39)	missense	possibly damaging	0.93
R6860:Tnxb	UTSW	17	34,932,131 (GRCm39)	missense	probably damaging	0.99
R6883:Tnxb	UTSW	17	34,937,493 (GRCm39)	missense	probably damaging	1.00
R7049:Tnxb	UTSW	17	34,936,242 (GRCm39)	critical splice donor site	probably null
R7107:Tnxb	UTSW	17	34,890,314 (GRCm39)	missense	unknown
R7172:Tnxb	UTSW	17	34,914,994 (GRCm39)	missense	probably damaging	1.00
R7206:Tnxb	UTSW	17	34,923,075 (GRCm39)	missense	possibly damaging	0.71
R7219:Tnxb	UTSW	17	34,898,039 (GRCm39)	missense	probably benign	0.08
R7237:Tnxb	UTSW	17	34,901,170 (GRCm39)	missense	possibly damaging	0.82
R7257:Tnxb	UTSW	17	34,935,475 (GRCm39)	missense	probably benign	0.44
R7269:Tnxb	UTSW	17	34,914,428 (GRCm39)	missense	probably damaging	1.00
R7302:Tnxb	UTSW	17	34,897,875 (GRCm39)	missense	probably benign	0.41
R7372:Tnxb	UTSW	17	34,936,228 (GRCm39)	missense	possibly damaging	0.72
R7384:Tnxb	UTSW	17	34,937,492 (GRCm39)	missense	probably damaging	1.00
R7447:Tnxb	UTSW	17	34,937,444 (GRCm39)	missense	probably damaging	1.00
R7449:Tnxb	UTSW	17	34,922,335 (GRCm39)	missense	possibly damaging	0.93
R7480:Tnxb	UTSW	17	34,934,747 (GRCm39)	missense	probably damaging	0.96
R7506:Tnxb	UTSW	17	34,934,665 (GRCm39)	missense	possibly damaging	0.89
R7586:Tnxb	UTSW	17	34,935,382 (GRCm39)	missense	probably damaging	0.98
R7688:Tnxb	UTSW	17	34,890,880 (GRCm39)	missense	probably benign	0.23
R7690:Tnxb	UTSW	17	34,908,501 (GRCm39)	missense	probably damaging	1.00
R7690:Tnxb	UTSW	17	34,908,494 (GRCm39)	missense	probably benign	0.03
R7732:Tnxb	UTSW	17	34,913,254 (GRCm39)	missense	probably damaging	1.00
R7735:Tnxb	UTSW	17	34,890,398 (GRCm39)	missense	unknown
R7760:Tnxb	UTSW	17	34,931,911 (GRCm39)	missense	probably damaging	0.96
R7874:Tnxb	UTSW	17	34,930,417 (GRCm39)	missense	probably damaging	1.00
R7909:Tnxb	UTSW	17	34,911,428 (GRCm39)	missense	probably benign	0.02
R7922:Tnxb	UTSW	17	34,933,577 (GRCm39)	missense	probably damaging	1.00
R7931:Tnxb	UTSW	17	34,907,672 (GRCm39)	missense	probably damaging	1.00
R7949:Tnxb	UTSW	17	34,936,103 (GRCm39)	missense	probably damaging	1.00
R7953:Tnxb	UTSW	17	34,929,077 (GRCm39)	missense	probably benign	0.03
R7953:Tnxb	UTSW	17	34,928,509 (GRCm39)	missense	possibly damaging	0.86
R7977:Tnxb	UTSW	17	34,929,194 (GRCm39)	missense	possibly damaging	0.92
R7985:Tnxb	UTSW	17	34,935,984 (GRCm39)	critical splice donor site	probably null
R7987:Tnxb	UTSW	17	34,929,194 (GRCm39)	missense	possibly damaging	0.92
R8040:Tnxb	UTSW	17	34,935,532 (GRCm39)	missense	probably damaging	1.00
R8053:Tnxb	UTSW	17	34,923,153 (GRCm39)	missense	probably damaging	0.98
R8074:Tnxb	UTSW	17	34,922,955 (GRCm39)	missense	probably benign	0.32
R8089:Tnxb	UTSW	17	34,891,763 (GRCm39)	missense	unknown
R8169:Tnxb	UTSW	17	34,918,181 (GRCm39)	missense	possibly damaging	0.96
R8348:Tnxb	UTSW	17	34,929,102 (GRCm39)	missense	possibly damaging	0.92
R8352:Tnxb	UTSW	17	34,908,381 (GRCm39)	missense	probably damaging	1.00
R8362:Tnxb	UTSW	17	34,931,946 (GRCm39)	missense	probably damaging	0.99
R8452:Tnxb	UTSW	17	34,908,381 (GRCm39)	missense	probably damaging	1.00
R8527:Tnxb	UTSW	17	34,907,634 (GRCm39)	missense	probably damaging	1.00
R8754:Tnxb	UTSW	17	34,934,882 (GRCm39)	missense	probably damaging	1.00
R8813:Tnxb	UTSW	17	34,938,136 (GRCm39)	missense	probably damaging	1.00
R8936:Tnxb	UTSW	17	34,904,646 (GRCm39)	missense	probably damaging	1.00
R8986:Tnxb	UTSW	17	34,897,646 (GRCm39)	missense	possibly damaging	0.66
R9001:Tnxb	UTSW	17	34,922,410 (GRCm39)	missense	probably benign	0.32
R9215:Tnxb	UTSW	17	34,891,564 (GRCm39)	missense	unknown
R9226:Tnxb	UTSW	17	34,904,766 (GRCm39)	missense	probably damaging	1.00
R9276:Tnxb	UTSW	17	34,929,134 (GRCm39)	missense	possibly damaging	0.60
R9279:Tnxb	UTSW	17	34,898,088 (GRCm39)	missense	possibly damaging	0.46
R9363:Tnxb	UTSW	17	34,917,294 (GRCm39)	missense	possibly damaging	0.93
R9367:Tnxb	UTSW	17	34,931,993 (GRCm39)	missense	probably damaging	1.00
R9494:Tnxb	UTSW	17	34,904,796 (GRCm39)	missense	probably damaging	1.00
R9606:Tnxb	UTSW	17	34,914,578 (GRCm39)	missense	possibly damaging	0.82
R9650:Tnxb	UTSW	17	34,930,629 (GRCm39)	missense	probably damaging	0.99
R9677:Tnxb	UTSW	17	34,917,878 (GRCm39)	missense	possibly damaging	0.93
R9690:Tnxb	UTSW	17	34,936,171 (GRCm39)	missense	probably damaging	1.00
R9761:Tnxb	UTSW	17	34,903,987 (GRCm39)	missense	probably benign	0.32
X0004:Tnxb	UTSW	17	34,922,389 (GRCm39)	missense	possibly damaging	0.71
X0010:Tnxb	UTSW	17	34,890,908 (GRCm39)	missense	probably damaging	1.00
X0019:Tnxb	UTSW	17	34,913,163 (GRCm39)	missense	possibly damaging	0.51
X0063:Tnxb	UTSW	17	34,922,482 (GRCm39)	missense	probably damaging	0.98
X0064:Tnxb	UTSW	17	34,913,006 (GRCm39)	missense	probably damaging	1.00
Z1177:Tnxb	UTSW	17	34,937,700 (GRCm39)	missense	probably damaging	0.99
Z1177:Tnxb	UTSW	17	34,902,305 (GRCm39)	missense	probably damaging	1.00
Z1177:Tnxb	UTSW	17	34,890,740 (GRCm39)	missense	unknown

Posted On

2015-12-18