Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02972:Vmn1r87'

365864

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r87

Ensembl Gene

ENSMUSG00000070815

Gene Name

vomeronasal 1 receptor 87

Synonyms

V1rk1

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.050) question?

Stock #

IGL02972

Quality Score

Status

Chromosome

Chromosomal Location

12865398-12866285 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to T at 12866256 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Stop codon at position 10 (Y10*)

Ref Sequence

ENSEMBL: ENSMUSP00000154184 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094827] [ENSMUST00000211249] [ENSMUST00000227443] [ENSMUST00000228800]

AlphaFold

Q8R255

Predicted Effect

probably null
Transcript: ENSMUST00000094827
AA Change: Y10*

SMART Domains

Protein: ENSMUSP00000092422
Gene: ENSMUSG00000070815
AA Change: Y10*

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	285	1.2e-11	PFAM
Pfam:V1R	14	280	1.8e-36	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000211249
AA Change: Y10*

Predicted Effect

probably null
Transcript: ENSMUST00000227443
AA Change: Y10*

Predicted Effect

probably null
Transcript: ENSMUST00000228800
AA Change: Y10*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410137M14Rik	T	A	17: 37,289,412 (GRCm39)	I105F	possibly damaging	Het
Bmpr1b	C	T	3: 141,576,519 (GRCm39)	D105N	probably benign	Het
Ces2e	A	T	8: 105,653,693 (GRCm39)	S44C	probably damaging	Het
Chd7	T	A	4: 8,855,174 (GRCm39)	N2134K	probably benign	Het
Chst15	T	C	7: 131,870,902 (GRCm39)	D211G	probably damaging	Het
Dpp4	T	C	2: 62,182,569 (GRCm39)	S571G	probably damaging	Het
Gna11	T	C	10: 81,369,225 (GRCm39)	I113V	probably benign	Het
Grm3	T	C	5: 9,562,410 (GRCm39)	Y480C	probably damaging	Het
Mccc1	C	T	3: 36,039,238 (GRCm39)	V252I	possibly damaging	Het
Nol12	A	G	15: 78,824,799 (GRCm39)	T209A	probably damaging	Het
Or2y14	G	A	11: 49,404,918 (GRCm39)	G151D	probably damaging	Het
Or52a33	A	G	7: 103,289,101 (GRCm39)	M82T	probably damaging	Het
Or7e168	T	C	9: 19,720,238 (GRCm39)	F208S	probably damaging	Het
P3h1	C	A	4: 119,105,157 (GRCm39)	Q712K	possibly damaging	Het
Per2	T	A	1: 91,351,703 (GRCm39)	E934D	possibly damaging	Het
Pfkl	T	C	10: 77,824,108 (GRCm39)	D760G	probably benign	Het
Piezo2	C	A	18: 63,197,856 (GRCm39)		probably benign	Het
Pkd1l1	C	T	11: 8,813,908 (GRCm39)	R1481Q	probably damaging	Het
Plpp3	T	C	4: 105,065,989 (GRCm39)	V189A	possibly damaging	Het
Pnpla1	A	G	17: 29,105,921 (GRCm39)	E592G	probably null	Het
Prdm2	A	T	4: 142,858,736 (GRCm39)	M1518K	probably benign	Het
Rhbdl3	G	A	11: 80,222,742 (GRCm39)		probably benign	Het
Rnf145	C	T	11: 44,454,865 (GRCm39)	S582F	probably benign	Het
Rsf1	A	G	7: 97,310,533 (GRCm39)	D421G	probably benign	Het
Serac1	A	C	17: 6,121,039 (GRCm39)	L85*	probably null	Het
Slc43a1	T	G	2: 84,690,462 (GRCm39)	V460G	probably damaging	Het
Slc7a6	G	A	8: 106,906,059 (GRCm39)	C97Y	probably damaging	Het
Slco5a1	A	T	1: 13,060,379 (GRCm39)	L114*	probably null	Het
Stxbp2	A	T	8: 3,691,971 (GRCm39)	I538F	probably benign	Het
Taok1	A	G	11: 77,450,584 (GRCm39)	V396A	probably benign	Het
Tmem232	T	A	17: 65,783,668 (GRCm39)	H233L	probably benign	Het
Tmprss11c	C	T	5: 86,385,692 (GRCm39)	S247N	possibly damaging	Het
Tnc	C	T	4: 63,894,715 (GRCm39)	S1557N	probably benign	Het
Txlng	A	G	X: 161,590,551 (GRCm39)	M94T	probably damaging	Het
Ube2b	A	T	11: 51,879,509 (GRCm39)	I87K	probably damaging	Het
Ubr5	A	T	15: 38,042,196 (GRCm39)	S133R	probably damaging	Het
Ugt1a5	C	T	1: 88,094,144 (GRCm39)	T124I	probably benign	Het
Vamp1	G	T	6: 125,196,610 (GRCm39)	R117L	probably benign	Het
Zan	G	A	5: 137,461,948 (GRCm39)	T1077I	unknown	Het
Zc2hc1b	C	A	10: 13,047,025 (GRCm39)	V29F	probably damaging	Het
Zfp597	T	C	16: 3,684,387 (GRCm39)	D123G	probably benign	Het

Other mutations in Vmn1r87

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01400:Vmn1r87	APN	7	12,866,230 (GRCm39)	missense	probably damaging	1.00
IGL01577:Vmn1r87	APN	7	12,865,775 (GRCm39)	missense	probably benign	0.00
IGL03246:Vmn1r87	APN	7	12,866,288 (GRCm39)	utr 5 prime	probably benign
PIT4142001:Vmn1r87	UTSW	7	12,866,112 (GRCm39)	missense	probably benign	0.00
R0153:Vmn1r87	UTSW	7	12,866,211 (GRCm39)	missense	probably damaging	1.00
R0502:Vmn1r87	UTSW	7	12,865,583 (GRCm39)	missense	probably damaging	1.00
R0658:Vmn1r87	UTSW	7	12,865,756 (GRCm39)	missense	probably damaging	1.00
R1589:Vmn1r87	UTSW	7	12,865,703 (GRCm39)	missense	possibly damaging	0.46
R1731:Vmn1r87	UTSW	7	12,865,703 (GRCm39)	missense	possibly damaging	0.46
R2027:Vmn1r87	UTSW	7	12,865,823 (GRCm39)	missense	probably damaging	0.99
R2044:Vmn1r87	UTSW	7	12,865,748 (GRCm39)	missense	probably benign	0.02
R3124:Vmn1r87	UTSW	7	12,865,493 (GRCm39)	missense	probably damaging	1.00
R4208:Vmn1r87	UTSW	7	12,866,185 (GRCm39)	missense	probably benign	0.37
R4731:Vmn1r87	UTSW	7	12,866,254 (GRCm39)	missense	possibly damaging	0.92
R4732:Vmn1r87	UTSW	7	12,866,254 (GRCm39)	missense	possibly damaging	0.92
R4733:Vmn1r87	UTSW	7	12,866,254 (GRCm39)	missense	possibly damaging	0.92
R5079:Vmn1r87	UTSW	7	12,866,253 (GRCm39)	missense	probably benign	0.01
R5125:Vmn1r87	UTSW	7	12,865,792 (GRCm39)	missense	possibly damaging	0.79
R5178:Vmn1r87	UTSW	7	12,865,792 (GRCm39)	missense	possibly damaging	0.79
R6599:Vmn1r87	UTSW	7	12,865,886 (GRCm39)	nonsense	probably null
R7067:Vmn1r87	UTSW	7	12,865,849 (GRCm39)	missense	probably benign	0.02
R7560:Vmn1r87	UTSW	7	12,865,745 (GRCm39)	missense	probably damaging	1.00
R7574:Vmn1r87	UTSW	7	12,865,613 (GRCm39)	missense	probably benign	0.01
R7910:Vmn1r87	UTSW	7	12,865,832 (GRCm39)	missense	probably damaging	1.00
R8040:Vmn1r87	UTSW	7	12,866,086 (GRCm39)	missense	possibly damaging	0.87
R8220:Vmn1r87	UTSW	7	12,865,427 (GRCm39)	missense	possibly damaging	0.72
R9690:Vmn1r87	UTSW	7	12,866,263 (GRCm39)	missense	probably benign	0.01
X0028:Vmn1r87	UTSW	7	12,865,910 (GRCm39)	missense	possibly damaging	0.52

Posted On

2015-12-18