Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02973:Zfp942'

365910

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp942

Ensembl Gene

ENSMUSG00000071267

Gene Name

zinc finger protein 942

Synonyms

3110048L19Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.066) question?

Stock #

IGL02973

Quality Score

Status

Chromosome

Chromosomal Location

22145941-22181445 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to G at 22151972 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000089494 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074295] [ENSMUST00000091879]

AlphaFold

B8JJA7

Predicted Effect

probably null
Transcript: ENSMUST00000074295

SMART Domains

Protein: ENSMUSP00000073907
Gene: ENSMUSG00000071267

Domain	Start	End	E-Value	Type
KRAB	13	69	6.55e-19	SMART
ZnF_C2H2	183	205	1.16e-1	SMART
ZnF_C2H2	211	233	8.22e-2	SMART
ZnF_C2H2	239	261	5.14e-3	SMART
ZnF_C2H2	267	289	8.02e-5	SMART
ZnF_C2H2	295	317	2.32e-1	SMART
ZnF_C2H2	323	345	1.6e-4	SMART
ZnF_C2H2	351	373	8.94e-3	SMART
ZnF_C2H2	379	401	1.95e-3	SMART
ZnF_C2H2	407	429	2.24e-3	SMART
ZnF_C2H2	435	457	7.49e-5	SMART
ZnF_C2H2	463	485	2.99e-4	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000091879

SMART Domains

Protein: ENSMUSP00000089494
Gene: ENSMUSG00000071267

Domain	Start	End	E-Value	Type
KRAB	13	69	6.55e-19	SMART
ZnF_C2H2	183	205	1.16e-1	SMART
ZnF_C2H2	211	233	8.22e-2	SMART
ZnF_C2H2	239	261	5.14e-3	SMART
ZnF_C2H2	267	289	8.02e-5	SMART
ZnF_C2H2	295	317	2.32e-1	SMART
ZnF_C2H2	323	345	1.6e-4	SMART
ZnF_C2H2	351	373	8.94e-3	SMART
ZnF_C2H2	379	401	1.95e-3	SMART
ZnF_C2H2	407	429	2.24e-3	SMART
ZnF_C2H2	435	457	7.49e-5	SMART
ZnF_C2H2	463	485	2.99e-4	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ada	A	G	2: 163,573,053 (GRCm39)	L193P	probably benign	Het
Ago2	A	T	15: 72,995,314 (GRCm39)		probably benign	Het
Ankrd26	A	G	6: 118,500,511 (GRCm39)	S987P	probably damaging	Het
Ap2a2	T	C	7: 141,211,277 (GRCm39)	F938L	possibly damaging	Het
Arhgap35	A	G	7: 16,296,803 (GRCm39)	V754A	possibly damaging	Het
Atp10b	A	T	11: 43,088,336 (GRCm39)	N314I	probably damaging	Het
Atp5f1a	T	C	18: 77,867,849 (GRCm39)	V291A	probably damaging	Het
Ccm2	C	A	11: 6,534,544 (GRCm39)	P19T	probably damaging	Het
Cdc5l	C	A	17: 45,715,573 (GRCm39)	A680S	probably benign	Het
Cds1	A	G	5: 101,960,376 (GRCm39)	T276A	probably damaging	Het
Cit	A	G	5: 116,144,058 (GRCm39)	R1976G	possibly damaging	Het
Col6a5	T	C	9: 105,803,020 (GRCm39)	D1315G	unknown	Het
Emilin1	T	G	5: 31,078,007 (GRCm39)	L922R	probably damaging	Het
Fank1	T	C	7: 133,478,578 (GRCm39)	L213P	probably damaging	Het
Foxc2	T	C	8: 121,844,788 (GRCm39)	S479P	probably benign	Het
Golgb1	G	A	16: 36,732,442 (GRCm39)	R563H	possibly damaging	Het
Hoxb13	A	G	11: 96,085,669 (GRCm39)	Y134C	probably damaging	Het
Krtap4-16	A	T	11: 99,742,167 (GRCm39)	C78S	possibly damaging	Het
Lars1	C	T	18: 42,347,824 (GRCm39)		probably null	Het
Lipe	T	C	7: 25,083,057 (GRCm39)	N740S	probably damaging	Het
Mbd1	C	T	18: 74,408,498 (GRCm39)		probably benign	Het
Mbd5	A	G	2: 49,203,721 (GRCm39)	D1700G	probably damaging	Het
Mpp7	A	G	18: 7,403,297 (GRCm39)	Y338H	probably damaging	Het
Pdgfrl	A	G	8: 41,438,631 (GRCm39)	D189G	probably damaging	Het
Pira12	T	C	7: 3,900,239 (GRCm39)	Y121C	probably damaging	Het
Plxnc1	T	C	10: 94,646,546 (GRCm39)	N1293S	probably damaging	Het
Ppm1e	C	A	11: 87,131,488 (GRCm39)	A302S	probably damaging	Het
Rassf8	A	G	6: 145,762,916 (GRCm39)		probably benign	Het
Rttn	T	C	18: 88,990,618 (GRCm39)	W52R	probably damaging	Het
Skint8	T	C	4: 111,796,790 (GRCm39)	V298A	probably benign	Het
Tulp1	A	T	17: 28,577,516 (GRCm39)		probably benign	Het
Unc5c	T	A	3: 141,494,651 (GRCm39)	D321E	probably benign	Het
Usp16	G	A	16: 87,276,627 (GRCm39)	C654Y	probably damaging	Het
Vwce	G	A	19: 10,632,764 (GRCm39)	W575*	probably null	Het
Wdr89	T	G	12: 75,679,873 (GRCm39)	D127A	probably damaging	Het
Zc3h6	G	A	2: 128,839,715 (GRCm39)	R176Q	probably damaging	Het

Other mutations in Zfp942

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00557:Zfp942	APN	17	22,148,042 (GRCm39)	missense	probably benign
IGL00586:Zfp942	APN	17	22,147,605 (GRCm39)	missense	probably damaging	1.00
IGL03212:Zfp942	APN	17	22,148,445 (GRCm39)	nonsense	probably null
IGL03382:Zfp942	APN	17	22,148,083 (GRCm39)	missense	probably benign	0.04
R0008:Zfp942	UTSW	17	22,147,319 (GRCm39)	missense	probably damaging	1.00
R0113:Zfp942	UTSW	17	22,148,066 (GRCm39)	missense	probably benign	0.18
R0244:Zfp942	UTSW	17	22,147,553 (GRCm39)	missense	probably benign	0.02
R0369:Zfp942	UTSW	17	22,148,017 (GRCm39)	missense	probably benign	0.41
R1664:Zfp942	UTSW	17	22,147,420 (GRCm39)	missense	possibly damaging	0.83
R1824:Zfp942	UTSW	17	22,147,522 (GRCm39)	missense	probably damaging	1.00
R4545:Zfp942	UTSW	17	22,147,285 (GRCm39)	missense	probably benign	0.00
R4785:Zfp942	UTSW	17	22,148,400 (GRCm39)	missense	probably damaging	1.00
R5493:Zfp942	UTSW	17	22,151,985 (GRCm39)	missense	probably null	0.66
R6568:Zfp942	UTSW	17	22,148,043 (GRCm39)	missense	probably benign	0.14
R6733:Zfp942	UTSW	17	22,147,733 (GRCm39)	nonsense	probably null
R7650:Zfp942	UTSW	17	22,147,818 (GRCm39)	missense	probably benign	0.07
R7935:Zfp942	UTSW	17	22,148,208 (GRCm39)	nonsense	probably null
R8065:Zfp942	UTSW	17	22,149,391 (GRCm39)	missense	probably damaging	0.96
R8067:Zfp942	UTSW	17	22,149,391 (GRCm39)	missense	probably damaging	0.96
R8237:Zfp942	UTSW	17	22,147,226 (GRCm39)	missense	possibly damaging	0.92
R8513:Zfp942	UTSW	17	22,147,282 (GRCm39)	missense	probably benign
R9468:Zfp942	UTSW	17	22,148,422 (GRCm39)	missense	probably benign	0.24
R9539:Zfp942	UTSW	17	22,148,014 (GRCm39)	missense	probably damaging	1.00
R9782:Zfp942	UTSW	17	22,147,463 (GRCm39)	missense	probably benign	0.05
X0025:Zfp942	UTSW	17	22,148,288 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-12-18