Incidental Mutation 'R4774:Tnr'
| ID |
367732 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnr
|
| Ensembl Gene |
ENSMUSG00000015829 |
| Gene Name |
tenascin R |
| Synonyms |
J1-tenascin, restrictin, janusin, TN-R |
| MMRRC Submission |
042412-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4774 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
159351339-159759299 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 159724636 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 1109
(L1109Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141553
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000111669]
[ENSMUST00000192069]
|
| AlphaFold |
Q8BYI9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000111669
AA Change: L1109Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000107298
Gene: ENSMUSG00000015829
AA Change: L1109Q
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_like
|
203 |
231 |
3.87e1 |
SMART |
|
EGF_like
|
234 |
262 |
3.16e1 |
SMART |
|
EGF_like
|
265 |
293 |
2.8e1 |
SMART |
|
EGF
|
296 |
324 |
2.43e1 |
SMART |
|
FN3
|
326 |
404 |
4.77e-8 |
SMART |
|
FN3
|
415 |
493 |
3.1e-7 |
SMART |
|
FN3
|
504 |
583 |
2.01e-6 |
SMART |
|
FN3
|
594 |
675 |
1.98e-5 |
SMART |
|
FN3
|
686 |
763 |
3.29e-11 |
SMART |
|
FN3
|
774 |
851 |
3.32e-7 |
SMART |
|
FN3
|
864 |
942 |
3.73e-10 |
SMART |
|
FN3
|
953 |
1031 |
2.28e-5 |
SMART |
|
FN3
|
1041 |
1118 |
8.56e-10 |
SMART |
|
FBG
|
1133 |
1343 |
2.69e-133 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000192069
AA Change: L1109Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000141553
Gene: ENSMUSG00000015829
AA Change: L1109Q
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_like
|
203 |
231 |
3.87e1 |
SMART |
|
EGF_like
|
234 |
262 |
3.16e1 |
SMART |
|
EGF_like
|
265 |
293 |
2.8e1 |
SMART |
|
EGF
|
296 |
324 |
2.43e1 |
SMART |
|
FN3
|
326 |
404 |
4.77e-8 |
SMART |
|
FN3
|
415 |
493 |
3.1e-7 |
SMART |
|
FN3
|
504 |
583 |
2.01e-6 |
SMART |
|
FN3
|
594 |
675 |
1.98e-5 |
SMART |
|
FN3
|
686 |
763 |
3.29e-11 |
SMART |
|
FN3
|
774 |
851 |
3.32e-7 |
SMART |
|
FN3
|
864 |
942 |
3.73e-10 |
SMART |
|
FN3
|
953 |
1031 |
2.28e-5 |
SMART |
|
FN3
|
1041 |
1118 |
8.56e-10 |
SMART |
|
FBG
|
1133 |
1343 |
2.69e-133 |
SMART |
|
| Meta Mutation Damage Score |
0.7685 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.9%
|
| Validation Efficiency |
98% (97/99) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of sodium channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013]
PHENOTYPE: In spite of having decreased conduction velocity in the optic nerve and ultrastrucural alterations within the hippocampus, homozygous null mice are viable, fertile, and display normal behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc9 |
T |
C |
6: 142,585,043 (GRCm39) |
I844V |
probably damaging |
Het |
| Acnat1 |
T |
A |
4: 49,450,784 (GRCm39) |
Y109F |
probably benign |
Het |
| Alox12b |
T |
C |
11: 69,054,033 (GRCm39) |
V205A |
probably benign |
Het |
| Arl6ip1 |
G |
A |
7: 117,721,208 (GRCm39) |
R77C |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,666,730 (GRCm39) |
C1156R |
possibly damaging |
Het |
| Atp8b3 |
A |
C |
10: 80,372,156 (GRCm39) |
N24K |
probably damaging |
Het |
| Bdh1 |
T |
C |
16: 31,273,954 (GRCm39) |
V209A |
possibly damaging |
Het |
| Blm |
A |
T |
7: 80,113,596 (GRCm39) |
C1234S |
probably damaging |
Het |
| Caml |
A |
G |
13: 55,779,740 (GRCm39) |
D271G |
possibly damaging |
Het |
| Capn11 |
T |
C |
17: 45,944,006 (GRCm39) |
D545G |
probably benign |
Het |
| Catspere1 |
T |
C |
1: 177,765,304 (GRCm39) |
|
noncoding transcript |
Het |
| Cep128 |
T |
C |
12: 91,200,969 (GRCm39) |
E347G |
probably damaging |
Het |
| Cngb3 |
A |
G |
4: 19,415,713 (GRCm39) |
T408A |
possibly damaging |
Het |
| Coa8 |
A |
G |
12: 111,679,823 (GRCm39) |
T33A |
possibly damaging |
Het |
| Cog1 |
G |
A |
11: 113,548,253 (GRCm39) |
R18Q |
possibly damaging |
Het |
| Cps1 |
T |
C |
1: 67,259,671 (GRCm39) |
F1338L |
probably damaging |
Het |
| Csmd1 |
T |
C |
8: 16,059,369 (GRCm39) |
H2122R |
probably benign |
Het |
| Ctu2 |
T |
G |
8: 123,207,851 (GRCm39) |
S26A |
probably benign |
Het |
| Dbf4 |
G |
A |
5: 8,453,062 (GRCm39) |
|
probably benign |
Het |
| Ddx23 |
A |
T |
15: 98,545,116 (GRCm39) |
D663E |
probably benign |
Het |
| Dpep2 |
T |
C |
8: 106,717,388 (GRCm39) |
T123A |
possibly damaging |
Het |
| Eed |
A |
G |
7: 89,613,976 (GRCm39) |
I274T |
probably damaging |
Het |
| Eif3b |
A |
G |
5: 140,405,255 (GRCm39) |
D47G |
probably benign |
Het |
| Epas1 |
T |
C |
17: 87,113,186 (GRCm39) |
V124A |
probably damaging |
Het |
| Fer1l6 |
T |
C |
15: 58,449,798 (GRCm39) |
L668P |
probably damaging |
Het |
| Fnip2 |
C |
A |
3: 79,373,028 (GRCm39) |
E1017* |
probably null |
Het |
| Gm43517 |
A |
T |
12: 49,436,690 (GRCm39) |
|
probably benign |
Het |
| Got1 |
A |
G |
19: 43,491,345 (GRCm39) |
|
probably null |
Het |
| H2-Eb2 |
T |
A |
17: 34,553,375 (GRCm39) |
V187E |
probably damaging |
Het |
| H2-Q1 |
T |
C |
17: 35,540,242 (GRCm39) |
|
probably benign |
Het |
| Hpgd |
T |
C |
8: 56,751,454 (GRCm39) |
V94A |
probably damaging |
Het |
| Htra1 |
T |
A |
7: 130,586,756 (GRCm39) |
N446K |
probably benign |
Het |
| Igkv3-4 |
T |
A |
6: 70,649,269 (GRCm39) |
S89R |
probably damaging |
Het |
| Immt |
C |
T |
6: 71,829,720 (GRCm39) |
T142I |
probably damaging |
Het |
| Itpkb |
C |
A |
1: 180,245,759 (GRCm39) |
P759T |
probably damaging |
Het |
| Jmjd1c |
G |
A |
10: 67,060,571 (GRCm39) |
V688I |
possibly damaging |
Het |
| Kbtbd13 |
G |
T |
9: 65,298,025 (GRCm39) |
R304S |
probably benign |
Het |
| Lama5 |
A |
C |
2: 179,827,734 (GRCm39) |
L2176R |
probably damaging |
Het |
| Lrp1b |
G |
C |
2: 40,551,544 (GRCm39) |
L418V |
probably null |
Het |
| Lrrc4b |
C |
A |
7: 44,111,796 (GRCm39) |
|
probably null |
Het |
| Lyst |
A |
G |
13: 13,915,182 (GRCm39) |
N3292S |
probably damaging |
Het |
| Mep1b |
A |
T |
18: 21,219,241 (GRCm39) |
I132F |
probably benign |
Het |
| Mettl2 |
A |
G |
11: 105,017,436 (GRCm39) |
|
probably null |
Het |
| Nherf2 |
T |
C |
17: 24,863,873 (GRCm39) |
M1V |
probably null |
Het |
| Niban1 |
A |
T |
1: 151,591,445 (GRCm39) |
D529V |
probably damaging |
Het |
| Nmd3 |
T |
C |
3: 69,652,569 (GRCm39) |
L385S |
probably benign |
Het |
| Nol4 |
T |
C |
18: 23,045,683 (GRCm39) |
E243G |
probably damaging |
Het |
| Odad1 |
T |
A |
7: 45,597,804 (GRCm39) |
S571R |
probably damaging |
Het |
| Or4l1 |
T |
A |
14: 50,166,726 (GRCm39) |
I92F |
probably damaging |
Het |
| Or51k1 |
A |
G |
7: 103,661,795 (GRCm39) |
I38T |
probably benign |
Het |
| Or5j3 |
A |
T |
2: 86,129,042 (GRCm39) |
N294I |
possibly damaging |
Het |
| Or8b52 |
A |
G |
9: 38,576,519 (GRCm39) |
I207T |
probably benign |
Het |
| Pcnp |
A |
G |
16: 55,837,522 (GRCm39) |
|
probably benign |
Het |
| Pla2g6 |
A |
C |
15: 79,171,818 (GRCm39) |
C680G |
probably damaging |
Het |
| Plekha7 |
G |
T |
7: 115,744,178 (GRCm39) |
D661E |
probably damaging |
Het |
| Prim1 |
A |
T |
10: 127,862,887 (GRCm39) |
|
probably benign |
Het |
| Psg29 |
T |
A |
7: 16,944,460 (GRCm39) |
N323K |
probably benign |
Het |
| Ptrh2 |
G |
A |
11: 86,580,833 (GRCm39) |
R150H |
probably damaging |
Het |
| Rasa1 |
A |
G |
13: 85,398,621 (GRCm39) |
|
probably benign |
Het |
| Rasa3 |
T |
C |
8: 13,627,501 (GRCm39) |
D667G |
probably benign |
Het |
| Rnase2a |
T |
C |
14: 51,493,201 (GRCm39) |
N55D |
probably damaging |
Het |
| Rsf1 |
GCGGCGGCGGCGGCGGCGGC |
GCGGCGGCGGCGGCGGCGGCGGCGGCGGC |
7: 97,229,123 (GRCm39) |
|
probably benign |
Het |
| Sbp |
T |
A |
17: 24,164,218 (GRCm39) |
N133K |
probably damaging |
Het |
| Scml4 |
A |
G |
10: 42,833,743 (GRCm39) |
|
probably benign |
Het |
| Sema5b |
T |
A |
16: 35,483,552 (GRCm39) |
N1063K |
probably damaging |
Het |
| Serpind1 |
C |
T |
16: 17,154,272 (GRCm39) |
T33M |
probably benign |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Slc15a2 |
A |
T |
16: 36,602,057 (GRCm39) |
L80* |
probably null |
Het |
| Sorcs3 |
A |
G |
19: 48,782,602 (GRCm39) |
D1039G |
probably benign |
Het |
| Spon1 |
A |
G |
7: 113,639,102 (GRCm39) |
E776G |
probably damaging |
Het |
| Tdp1 |
C |
T |
12: 99,868,623 (GRCm39) |
A259V |
possibly damaging |
Het |
| Tex46 |
C |
A |
4: 136,337,991 (GRCm39) |
P61Q |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,017,369 (GRCm39) |
R281C |
probably damaging |
Het |
| Tpra1 |
G |
A |
6: 88,887,661 (GRCm39) |
|
probably benign |
Het |
| Trim43c |
A |
T |
9: 88,729,705 (GRCm39) |
H383L |
possibly damaging |
Het |
| Trip6 |
A |
G |
5: 137,308,433 (GRCm39) |
C439R |
probably damaging |
Het |
| Tsen2 |
C |
T |
6: 115,552,894 (GRCm39) |
S398L |
possibly damaging |
Het |
| Tubgcp2 |
T |
C |
7: 139,576,074 (GRCm39) |
D863G |
probably damaging |
Het |
| Ube2d2a |
A |
G |
18: 35,903,498 (GRCm39) |
|
probably benign |
Het |
| Umad1 |
T |
A |
6: 8,427,181 (GRCm39) |
F145I |
probably damaging |
Het |
| Unc5c |
A |
T |
3: 141,534,278 (GRCm39) |
E933V |
probably damaging |
Het |
| Vmn1r208 |
A |
G |
13: 22,956,646 (GRCm39) |
F284L |
probably benign |
Het |
| Vmn2r53 |
T |
A |
7: 12,334,692 (GRCm39) |
R323* |
probably null |
Het |
| Zan |
G |
A |
5: 137,387,281 (GRCm39) |
T4924I |
unknown |
Het |
| Zfp597 |
G |
T |
16: 3,683,851 (GRCm39) |
Q302K |
probably benign |
Het |
|
| Other mutations in Tnr |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00432:Tnr
|
APN |
1 |
159,688,815 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00905:Tnr
|
APN |
1 |
159,679,752 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01396:Tnr
|
APN |
1 |
159,724,594 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01550:Tnr
|
APN |
1 |
159,701,828 (GRCm39) |
missense |
probably benign |
|
|
IGL01803:Tnr
|
APN |
1 |
159,695,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01845:Tnr
|
APN |
1 |
159,695,576 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01983:Tnr
|
APN |
1 |
159,691,349 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01985:Tnr
|
APN |
1 |
159,746,607 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL02210:Tnr
|
APN |
1 |
159,679,671 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL02486:Tnr
|
APN |
1 |
159,679,664 (GRCm39) |
splice site |
probably null |
|
|
IGL03210:Tnr
|
APN |
1 |
159,715,880 (GRCm39) |
missense |
probably benign |
0.00 |
|
Assiduous
|
UTSW |
1 |
159,719,593 (GRCm39) |
missense |
probably benign |
|
|
Grip
|
UTSW |
1 |
159,713,680 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
Persistent
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
Tenacious
|
UTSW |
1 |
159,701,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0002:Tnr
|
UTSW |
1 |
159,701,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0002:Tnr
|
UTSW |
1 |
159,701,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Tnr
|
UTSW |
1 |
159,679,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0042:Tnr
|
UTSW |
1 |
159,714,595 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0594:Tnr
|
UTSW |
1 |
159,677,905 (GRCm39) |
missense |
probably benign |
|
|
R0617:Tnr
|
UTSW |
1 |
159,695,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0637:Tnr
|
UTSW |
1 |
159,677,905 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R0682:Tnr
|
UTSW |
1 |
159,679,877 (GRCm39) |
nonsense |
probably null |
|
|
R1171:Tnr
|
UTSW |
1 |
159,685,780 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1185:Tnr
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
R1185:Tnr
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
R1185:Tnr
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
R1335:Tnr
|
UTSW |
1 |
159,695,600 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1540:Tnr
|
UTSW |
1 |
159,677,675 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1697:Tnr
|
UTSW |
1 |
159,679,600 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1938:Tnr
|
UTSW |
1 |
159,722,607 (GRCm39) |
nonsense |
probably null |
|
|
R1941:Tnr
|
UTSW |
1 |
159,677,704 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2021:Tnr
|
UTSW |
1 |
159,679,592 (GRCm39) |
missense |
probably benign |
|
|
R2022:Tnr
|
UTSW |
1 |
159,679,592 (GRCm39) |
missense |
probably benign |
|
|
R2051:Tnr
|
UTSW |
1 |
159,719,603 (GRCm39) |
missense |
probably benign |
|
|
R2157:Tnr
|
UTSW |
1 |
159,685,840 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2319:Tnr
|
UTSW |
1 |
159,677,618 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R2936:Tnr
|
UTSW |
1 |
159,715,932 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3015:Tnr
|
UTSW |
1 |
159,715,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3417:Tnr
|
UTSW |
1 |
159,722,612 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3739:Tnr
|
UTSW |
1 |
159,750,983 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R3977:Tnr
|
UTSW |
1 |
159,719,593 (GRCm39) |
missense |
probably benign |
|
|
R4232:Tnr
|
UTSW |
1 |
159,713,785 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4478:Tnr
|
UTSW |
1 |
159,712,326 (GRCm39) |
splice site |
probably null |
|
|
R4829:Tnr
|
UTSW |
1 |
159,685,974 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4837:Tnr
|
UTSW |
1 |
159,512,358 (GRCm39) |
intron |
probably benign |
|
|
R5111:Tnr
|
UTSW |
1 |
159,713,798 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5224:Tnr
|
UTSW |
1 |
159,750,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5249:Tnr
|
UTSW |
1 |
159,512,226 (GRCm39) |
intron |
probably benign |
|
|
R5730:Tnr
|
UTSW |
1 |
159,715,892 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5807:Tnr
|
UTSW |
1 |
159,714,500 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5832:Tnr
|
UTSW |
1 |
159,713,692 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5927:Tnr
|
UTSW |
1 |
159,740,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tnr
|
UTSW |
1 |
159,740,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6056:Tnr
|
UTSW |
1 |
159,714,479 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6063:Tnr
|
UTSW |
1 |
159,740,254 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6141:Tnr
|
UTSW |
1 |
159,714,692 (GRCm39) |
missense |
probably benign |
|
|
R6218:Tnr
|
UTSW |
1 |
159,715,884 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6275:Tnr
|
UTSW |
1 |
159,688,840 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6543:Tnr
|
UTSW |
1 |
159,751,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6626:Tnr
|
UTSW |
1 |
159,677,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7378:Tnr
|
UTSW |
1 |
159,712,432 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7587:Tnr
|
UTSW |
1 |
159,713,778 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7766:Tnr
|
UTSW |
1 |
159,715,880 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8140:Tnr
|
UTSW |
1 |
159,691,265 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Tnr
|
UTSW |
1 |
159,715,860 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8248:Tnr
|
UTSW |
1 |
159,719,663 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8374:Tnr
|
UTSW |
1 |
159,685,953 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8427:Tnr
|
UTSW |
1 |
159,713,801 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8465:Tnr
|
UTSW |
1 |
159,713,645 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8534:Tnr
|
UTSW |
1 |
159,746,585 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8753:Tnr
|
UTSW |
1 |
159,677,936 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8804:Tnr
|
UTSW |
1 |
159,685,882 (GRCm39) |
missense |
probably benign |
|
|
R8857:Tnr
|
UTSW |
1 |
159,713,728 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8917:Tnr
|
UTSW |
1 |
159,701,692 (GRCm39) |
nonsense |
probably null |
|
|
R8930:Tnr
|
UTSW |
1 |
159,740,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8932:Tnr
|
UTSW |
1 |
159,740,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8940:Tnr
|
UTSW |
1 |
159,685,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9096:Tnr
|
UTSW |
1 |
159,677,804 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9127:Tnr
|
UTSW |
1 |
159,713,680 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9205:Tnr
|
UTSW |
1 |
159,722,617 (GRCm39) |
missense |
probably benign |
|
|
R9311:Tnr
|
UTSW |
1 |
159,677,663 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9679:Tnr
|
UTSW |
1 |
159,719,608 (GRCm39) |
missense |
probably benign |
0.08 |
|
X0011:Tnr
|
UTSW |
1 |
159,716,908 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0028:Tnr
|
UTSW |
1 |
159,701,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Tnr
|
UTSW |
1 |
159,722,665 (GRCm39) |
missense |
probably benign |
0.29 |
|
Z1177:Tnr
|
UTSW |
1 |
159,679,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTTCCTCCTTACTATGGGGCG -3'
(R):5'- GGGATTTTCTACCAAGGCCTTG -3'
Sequencing Primer
(F):5'- CCTTACTATGGGGCGGGGAG -3'
(R):5'- CAAGGCCTTGGGAAAGGG -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation