Incidental Mutation 'R4774:Atp8b3'
| ID |
367778 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atp8b3
|
| Ensembl Gene |
ENSMUSG00000003341 |
| Gene Name |
ATPase, class I, type 8B, member 3 |
| Synonyms |
1700042F02Rik, 1700056N23Rik, SAPLT |
| MMRRC Submission |
042412-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.083)
|
| Stock # |
R4774 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
80355418-80374958 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 80372156 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 24
(N24K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000151571
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020383]
[ENSMUST00000057910]
[ENSMUST00000219648]
[ENSMUST00000220326]
|
| AlphaFold |
Q6UQ17 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000020383
AA Change: N24K
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000020383
Gene: ENSMUSG00000003341
AA Change: N24K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PhoLip_ATPase_N
|
20 |
97 |
9.3e-29 |
PFAM |
|
Pfam:E1-E2_ATPase
|
121 |
367 |
2.2e-10 |
PFAM |
|
Pfam:HAD
|
404 |
866 |
3.7e-17 |
PFAM |
|
Pfam:Cation_ATPase
|
481 |
580 |
8.3e-12 |
PFAM |
|
Pfam:PhoLip_ATPase_C
|
883 |
1135 |
4.2e-61 |
PFAM |
|
low complexity region
|
1140 |
1153 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000057910
|
| SMART Domains |
Protein: ENSMUSP00000049705
Gene: ENSMUSG00000047417
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
53 |
N/A |
INTRINSIC |
|
coiled coil region
|
83 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
180 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
381 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
453 |
N/A |
INTRINSIC |
|
low complexity region
|
468 |
479 |
N/A |
INTRINSIC |
|
low complexity region
|
507 |
525 |
N/A |
INTRINSIC |
|
low complexity region
|
533 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
561 |
583 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
682 |
N/A |
INTRINSIC |
|
Pfam:EloA-BP1
|
794 |
954 |
3.8e-72 |
PFAM |
|
EXOIII
|
1051 |
1210 |
2.36e-38 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182682
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000219648
AA Change: N24K
PolyPhen 2
Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000220326
AA Change: N24K
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.9%
|
| Validation Efficiency |
98% (97/99) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPase 8B; other members of this protein family are located on chromosomes 1, 15 and 18. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
PHENOTYPE: Litters sired by homozygous mutant mice are smaller than those sired by wild-type males. While sperm morphology and motility is intact in null sperm, fertilization rates are reduced due to impaired sperm-egg interactions. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc9 |
T |
C |
6: 142,585,043 (GRCm39) |
I844V |
probably damaging |
Het |
| Acnat1 |
T |
A |
4: 49,450,784 (GRCm39) |
Y109F |
probably benign |
Het |
| Alox12b |
T |
C |
11: 69,054,033 (GRCm39) |
V205A |
probably benign |
Het |
| Arl6ip1 |
G |
A |
7: 117,721,208 (GRCm39) |
R77C |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,666,730 (GRCm39) |
C1156R |
possibly damaging |
Het |
| Bdh1 |
T |
C |
16: 31,273,954 (GRCm39) |
V209A |
possibly damaging |
Het |
| Blm |
A |
T |
7: 80,113,596 (GRCm39) |
C1234S |
probably damaging |
Het |
| Caml |
A |
G |
13: 55,779,740 (GRCm39) |
D271G |
possibly damaging |
Het |
| Capn11 |
T |
C |
17: 45,944,006 (GRCm39) |
D545G |
probably benign |
Het |
| Catspere1 |
T |
C |
1: 177,765,304 (GRCm39) |
|
noncoding transcript |
Het |
| Cep128 |
T |
C |
12: 91,200,969 (GRCm39) |
E347G |
probably damaging |
Het |
| Cngb3 |
A |
G |
4: 19,415,713 (GRCm39) |
T408A |
possibly damaging |
Het |
| Coa8 |
A |
G |
12: 111,679,823 (GRCm39) |
T33A |
possibly damaging |
Het |
| Cog1 |
G |
A |
11: 113,548,253 (GRCm39) |
R18Q |
possibly damaging |
Het |
| Cps1 |
T |
C |
1: 67,259,671 (GRCm39) |
F1338L |
probably damaging |
Het |
| Csmd1 |
T |
C |
8: 16,059,369 (GRCm39) |
H2122R |
probably benign |
Het |
| Ctu2 |
T |
G |
8: 123,207,851 (GRCm39) |
S26A |
probably benign |
Het |
| Dbf4 |
G |
A |
5: 8,453,062 (GRCm39) |
|
probably benign |
Het |
| Ddx23 |
A |
T |
15: 98,545,116 (GRCm39) |
D663E |
probably benign |
Het |
| Dpep2 |
T |
C |
8: 106,717,388 (GRCm39) |
T123A |
possibly damaging |
Het |
| Eed |
A |
G |
7: 89,613,976 (GRCm39) |
I274T |
probably damaging |
Het |
| Eif3b |
A |
G |
5: 140,405,255 (GRCm39) |
D47G |
probably benign |
Het |
| Epas1 |
T |
C |
17: 87,113,186 (GRCm39) |
V124A |
probably damaging |
Het |
| Fer1l6 |
T |
C |
15: 58,449,798 (GRCm39) |
L668P |
probably damaging |
Het |
| Fnip2 |
C |
A |
3: 79,373,028 (GRCm39) |
E1017* |
probably null |
Het |
| Gm43517 |
A |
T |
12: 49,436,690 (GRCm39) |
|
probably benign |
Het |
| Got1 |
A |
G |
19: 43,491,345 (GRCm39) |
|
probably null |
Het |
| H2-Eb2 |
T |
A |
17: 34,553,375 (GRCm39) |
V187E |
probably damaging |
Het |
| H2-Q1 |
T |
C |
17: 35,540,242 (GRCm39) |
|
probably benign |
Het |
| Hpgd |
T |
C |
8: 56,751,454 (GRCm39) |
V94A |
probably damaging |
Het |
| Htra1 |
T |
A |
7: 130,586,756 (GRCm39) |
N446K |
probably benign |
Het |
| Igkv3-4 |
T |
A |
6: 70,649,269 (GRCm39) |
S89R |
probably damaging |
Het |
| Immt |
C |
T |
6: 71,829,720 (GRCm39) |
T142I |
probably damaging |
Het |
| Itpkb |
C |
A |
1: 180,245,759 (GRCm39) |
P759T |
probably damaging |
Het |
| Jmjd1c |
G |
A |
10: 67,060,571 (GRCm39) |
V688I |
possibly damaging |
Het |
| Kbtbd13 |
G |
T |
9: 65,298,025 (GRCm39) |
R304S |
probably benign |
Het |
| Lama5 |
A |
C |
2: 179,827,734 (GRCm39) |
L2176R |
probably damaging |
Het |
| Lrp1b |
G |
C |
2: 40,551,544 (GRCm39) |
L418V |
probably null |
Het |
| Lrrc4b |
C |
A |
7: 44,111,796 (GRCm39) |
|
probably null |
Het |
| Lyst |
A |
G |
13: 13,915,182 (GRCm39) |
N3292S |
probably damaging |
Het |
| Mep1b |
A |
T |
18: 21,219,241 (GRCm39) |
I132F |
probably benign |
Het |
| Mettl2 |
A |
G |
11: 105,017,436 (GRCm39) |
|
probably null |
Het |
| Nherf2 |
T |
C |
17: 24,863,873 (GRCm39) |
M1V |
probably null |
Het |
| Niban1 |
A |
T |
1: 151,591,445 (GRCm39) |
D529V |
probably damaging |
Het |
| Nmd3 |
T |
C |
3: 69,652,569 (GRCm39) |
L385S |
probably benign |
Het |
| Nol4 |
T |
C |
18: 23,045,683 (GRCm39) |
E243G |
probably damaging |
Het |
| Odad1 |
T |
A |
7: 45,597,804 (GRCm39) |
S571R |
probably damaging |
Het |
| Or4l1 |
T |
A |
14: 50,166,726 (GRCm39) |
I92F |
probably damaging |
Het |
| Or51k1 |
A |
G |
7: 103,661,795 (GRCm39) |
I38T |
probably benign |
Het |
| Or5j3 |
A |
T |
2: 86,129,042 (GRCm39) |
N294I |
possibly damaging |
Het |
| Or8b52 |
A |
G |
9: 38,576,519 (GRCm39) |
I207T |
probably benign |
Het |
| Pcnp |
A |
G |
16: 55,837,522 (GRCm39) |
|
probably benign |
Het |
| Pla2g6 |
A |
C |
15: 79,171,818 (GRCm39) |
C680G |
probably damaging |
Het |
| Plekha7 |
G |
T |
7: 115,744,178 (GRCm39) |
D661E |
probably damaging |
Het |
| Prim1 |
A |
T |
10: 127,862,887 (GRCm39) |
|
probably benign |
Het |
| Psg29 |
T |
A |
7: 16,944,460 (GRCm39) |
N323K |
probably benign |
Het |
| Ptrh2 |
G |
A |
11: 86,580,833 (GRCm39) |
R150H |
probably damaging |
Het |
| Rasa1 |
A |
G |
13: 85,398,621 (GRCm39) |
|
probably benign |
Het |
| Rasa3 |
T |
C |
8: 13,627,501 (GRCm39) |
D667G |
probably benign |
Het |
| Rnase2a |
T |
C |
14: 51,493,201 (GRCm39) |
N55D |
probably damaging |
Het |
| Rsf1 |
GCGGCGGCGGCGGCGGCGGC |
GCGGCGGCGGCGGCGGCGGCGGCGGCGGC |
7: 97,229,123 (GRCm39) |
|
probably benign |
Het |
| Sbp |
T |
A |
17: 24,164,218 (GRCm39) |
N133K |
probably damaging |
Het |
| Scml4 |
A |
G |
10: 42,833,743 (GRCm39) |
|
probably benign |
Het |
| Sema5b |
T |
A |
16: 35,483,552 (GRCm39) |
N1063K |
probably damaging |
Het |
| Serpind1 |
C |
T |
16: 17,154,272 (GRCm39) |
T33M |
probably benign |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Slc15a2 |
A |
T |
16: 36,602,057 (GRCm39) |
L80* |
probably null |
Het |
| Sorcs3 |
A |
G |
19: 48,782,602 (GRCm39) |
D1039G |
probably benign |
Het |
| Spon1 |
A |
G |
7: 113,639,102 (GRCm39) |
E776G |
probably damaging |
Het |
| Tdp1 |
C |
T |
12: 99,868,623 (GRCm39) |
A259V |
possibly damaging |
Het |
| Tex46 |
C |
A |
4: 136,337,991 (GRCm39) |
P61Q |
probably benign |
Het |
| Tnr |
T |
A |
1: 159,724,636 (GRCm39) |
L1109Q |
probably damaging |
Het |
| Tns2 |
C |
T |
15: 102,017,369 (GRCm39) |
R281C |
probably damaging |
Het |
| Tpra1 |
G |
A |
6: 88,887,661 (GRCm39) |
|
probably benign |
Het |
| Trim43c |
A |
T |
9: 88,729,705 (GRCm39) |
H383L |
possibly damaging |
Het |
| Trip6 |
A |
G |
5: 137,308,433 (GRCm39) |
C439R |
probably damaging |
Het |
| Tsen2 |
C |
T |
6: 115,552,894 (GRCm39) |
S398L |
possibly damaging |
Het |
| Tubgcp2 |
T |
C |
7: 139,576,074 (GRCm39) |
D863G |
probably damaging |
Het |
| Ube2d2a |
A |
G |
18: 35,903,498 (GRCm39) |
|
probably benign |
Het |
| Umad1 |
T |
A |
6: 8,427,181 (GRCm39) |
F145I |
probably damaging |
Het |
| Unc5c |
A |
T |
3: 141,534,278 (GRCm39) |
E933V |
probably damaging |
Het |
| Vmn1r208 |
A |
G |
13: 22,956,646 (GRCm39) |
F284L |
probably benign |
Het |
| Vmn2r53 |
T |
A |
7: 12,334,692 (GRCm39) |
R323* |
probably null |
Het |
| Zan |
G |
A |
5: 137,387,281 (GRCm39) |
T4924I |
unknown |
Het |
| Zfp597 |
G |
T |
16: 3,683,851 (GRCm39) |
Q302K |
probably benign |
Het |
|
| Other mutations in Atp8b3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00333:Atp8b3
|
APN |
10 |
80,366,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00484:Atp8b3
|
APN |
10 |
80,361,998 (GRCm39) |
splice site |
probably benign |
|
|
IGL00904:Atp8b3
|
APN |
10 |
80,364,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01326:Atp8b3
|
APN |
10 |
80,360,210 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01368:Atp8b3
|
APN |
10 |
80,370,063 (GRCm39) |
splice site |
probably benign |
|
|
IGL01448:Atp8b3
|
APN |
10 |
80,356,256 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01556:Atp8b3
|
APN |
10 |
80,366,802 (GRCm39) |
nonsense |
probably null |
|
|
IGL01754:Atp8b3
|
APN |
10 |
80,366,795 (GRCm39) |
splice site |
probably null |
|
|
IGL01809:Atp8b3
|
APN |
10 |
80,355,845 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01895:Atp8b3
|
APN |
10 |
80,357,662 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02184:Atp8b3
|
APN |
10 |
80,363,067 (GRCm39) |
splice site |
probably benign |
|
|
IGL02224:Atp8b3
|
APN |
10 |
80,361,810 (GRCm39) |
splice site |
probably benign |
|
|
IGL02377:Atp8b3
|
APN |
10 |
80,356,128 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02405:Atp8b3
|
APN |
10 |
80,366,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03090:Atp8b3
|
APN |
10 |
80,366,438 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03244:Atp8b3
|
APN |
10 |
80,370,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4544001:Atp8b3
|
UTSW |
10 |
80,366,420 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0277:Atp8b3
|
UTSW |
10 |
80,362,743 (GRCm39) |
missense |
probably benign |
0.21 |
|
R0908:Atp8b3
|
UTSW |
10 |
80,355,918 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0973:Atp8b3
|
UTSW |
10 |
80,370,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1069:Atp8b3
|
UTSW |
10 |
80,366,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1087:Atp8b3
|
UTSW |
10 |
80,356,017 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Atp8b3
|
UTSW |
10 |
80,368,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1603:Atp8b3
|
UTSW |
10 |
80,361,619 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1606:Atp8b3
|
UTSW |
10 |
80,368,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1707:Atp8b3
|
UTSW |
10 |
80,357,635 (GRCm39) |
splice site |
probably null |
|
|
R1717:Atp8b3
|
UTSW |
10 |
80,364,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1876:Atp8b3
|
UTSW |
10 |
80,365,912 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1939:Atp8b3
|
UTSW |
10 |
80,361,220 (GRCm39) |
nonsense |
probably null |
|
|
R2138:Atp8b3
|
UTSW |
10 |
80,362,939 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2239:Atp8b3
|
UTSW |
10 |
80,366,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2429:Atp8b3
|
UTSW |
10 |
80,362,728 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2696:Atp8b3
|
UTSW |
10 |
80,370,017 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2910:Atp8b3
|
UTSW |
10 |
80,355,746 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R3424:Atp8b3
|
UTSW |
10 |
80,372,181 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3425:Atp8b3
|
UTSW |
10 |
80,372,181 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3432:Atp8b3
|
UTSW |
10 |
80,362,014 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3841:Atp8b3
|
UTSW |
10 |
80,365,540 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4515:Atp8b3
|
UTSW |
10 |
80,359,681 (GRCm39) |
missense |
probably benign |
|
|
R4518:Atp8b3
|
UTSW |
10 |
80,359,681 (GRCm39) |
missense |
probably benign |
|
|
R4519:Atp8b3
|
UTSW |
10 |
80,359,681 (GRCm39) |
missense |
probably benign |
|
|
R4619:Atp8b3
|
UTSW |
10 |
80,361,858 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4648:Atp8b3
|
UTSW |
10 |
80,361,457 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4709:Atp8b3
|
UTSW |
10 |
80,372,604 (GRCm39) |
splice site |
probably null |
|
|
R4796:Atp8b3
|
UTSW |
10 |
80,360,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5000:Atp8b3
|
UTSW |
10 |
80,357,676 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5398:Atp8b3
|
UTSW |
10 |
80,365,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5778:Atp8b3
|
UTSW |
10 |
80,356,007 (GRCm39) |
missense |
probably benign |
|
|
R5990:Atp8b3
|
UTSW |
10 |
80,361,531 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6124:Atp8b3
|
UTSW |
10 |
80,365,515 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6427:Atp8b3
|
UTSW |
10 |
80,356,157 (GRCm39) |
splice site |
probably null |
|
|
R6748:Atp8b3
|
UTSW |
10 |
80,361,058 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6756:Atp8b3
|
UTSW |
10 |
80,361,895 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7051:Atp8b3
|
UTSW |
10 |
80,365,552 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7051:Atp8b3
|
UTSW |
10 |
80,355,858 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7052:Atp8b3
|
UTSW |
10 |
80,355,858 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7418:Atp8b3
|
UTSW |
10 |
80,365,926 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7426:Atp8b3
|
UTSW |
10 |
80,365,463 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7625:Atp8b3
|
UTSW |
10 |
80,355,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7673:Atp8b3
|
UTSW |
10 |
80,360,240 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7921:Atp8b3
|
UTSW |
10 |
80,366,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8077:Atp8b3
|
UTSW |
10 |
80,366,858 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8235:Atp8b3
|
UTSW |
10 |
80,365,650 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8354:Atp8b3
|
UTSW |
10 |
80,361,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8454:Atp8b3
|
UTSW |
10 |
80,361,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8501:Atp8b3
|
UTSW |
10 |
80,355,980 (GRCm39) |
missense |
probably benign |
|
|
R8712:Atp8b3
|
UTSW |
10 |
80,365,923 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8962:Atp8b3
|
UTSW |
10 |
80,355,896 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9129:Atp8b3
|
UTSW |
10 |
80,368,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9333:Atp8b3
|
UTSW |
10 |
80,360,180 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9438:Atp8b3
|
UTSW |
10 |
80,361,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9486:Atp8b3
|
UTSW |
10 |
80,366,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9554:Atp8b3
|
UTSW |
10 |
80,360,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9570:Atp8b3
|
UTSW |
10 |
80,361,822 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9682:Atp8b3
|
UTSW |
10 |
80,371,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Atp8b3
|
UTSW |
10 |
80,364,407 (GRCm39) |
missense |
probably damaging |
0.96 |
|
RF006:Atp8b3
|
UTSW |
10 |
80,362,070 (GRCm39) |
missense |
probably benign |
0.15 |
|
Z1177:Atp8b3
|
UTSW |
10 |
80,366,911 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAACTCGAGAACTCTCAGGGTGG -3'
(R):5'- CCGATACTAGGAGCAGTTGG -3'
Sequencing Primer
(F):5'- GGTGGCTCCCTCACCCC -3'
(R):5'- GTCCAGTCCTGATGTTTACCAG -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation