Incidental Mutation 'R4793:Il1rap'
| ID |
368809 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Il1rap
|
| Ensembl Gene |
ENSMUSG00000022514 |
| Gene Name |
interleukin 1 receptor accessory protein |
| Synonyms |
IL-1RAcP, 6430709H04Rik, IL-1R AcP |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4793 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
26400454-26548867 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 26513984 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Alanine
at position 239
(D239A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133904
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023156]
[ENSMUST00000096129]
[ENSMUST00000166294]
[ENSMUST00000174171]
[ENSMUST00000174202]
|
| AlphaFold |
Q61730 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000023156
AA Change: D239A
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000023156
Gene: ENSMUSG00000022514
AA Change: D239A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
TIR
|
404 |
549 |
5.29e-36 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000096129
AA Change: D239A
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000093843
Gene: ENSMUSG00000022514
AA Change: D239A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
TIR
|
404 |
547 |
1.38e-25 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166294
AA Change: D239A
PolyPhen 2
Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000128100
Gene: ENSMUSG00000022514
AA Change: D239A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
TIR
|
404 |
547 |
1.38e-25 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174171
AA Change: D239A
PolyPhen 2
Score 0.095 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000133904
Gene: ENSMUSG00000022514
AA Change: D239A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
Blast:IG
|
251 |
312 |
1e-28 |
BLAST |
|
low complexity region
|
316 |
332 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174202
AA Change: D239A
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000134202
Gene: ENSMUSG00000022514
AA Change: D239A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
IG
|
32 |
132 |
1.21e-2 |
SMART |
|
IG
|
145 |
232 |
4.04e0 |
SMART |
|
IG
|
251 |
350 |
1.46e-5 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.9%
|
| Validation Efficiency |
100% (91/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009]
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal but show no biological response to IL-1. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca6 |
T |
A |
11: 110,082,544 (GRCm39) |
E1143V |
probably benign |
Het |
| Abi2 |
T |
A |
1: 60,448,963 (GRCm39) |
M1K |
probably null |
Het |
| Acp2 |
T |
C |
2: 91,037,134 (GRCm39) |
F205L |
probably benign |
Het |
| Adam17 |
T |
C |
12: 21,397,396 (GRCm39) |
N219D |
probably benign |
Het |
| Aldh2 |
T |
C |
5: 121,707,042 (GRCm39) |
S168G |
probably damaging |
Het |
| Arhgap15 |
A |
T |
2: 44,032,353 (GRCm39) |
E312D |
probably damaging |
Het |
| Calm5 |
T |
C |
13: 3,904,401 (GRCm39) |
S32P |
probably benign |
Het |
| Capn12 |
G |
A |
7: 28,592,094 (GRCm39) |
D671N |
probably benign |
Het |
| Ccdc73 |
A |
G |
2: 104,848,127 (GRCm39) |
|
probably null |
Het |
| Cdc20 |
T |
A |
4: 118,294,261 (GRCm39) |
I20F |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,167,129 (GRCm39) |
I1841N |
probably damaging |
Het |
| Cftr |
T |
C |
6: 18,226,087 (GRCm39) |
V345A |
probably damaging |
Het |
| Col15a1 |
T |
C |
4: 47,262,997 (GRCm39) |
S550P |
possibly damaging |
Het |
| Col4a4 |
A |
G |
1: 82,516,820 (GRCm39) |
Y133H |
unknown |
Het |
| Csmd1 |
A |
G |
8: 16,138,277 (GRCm39) |
S1592P |
probably damaging |
Het |
| Cts6 |
T |
A |
13: 61,349,626 (GRCm39) |
M56L |
probably benign |
Het |
| Cybb |
C |
G |
X: 9,316,989 (GRCm39) |
D246H |
probably benign |
Het |
| Dock5 |
A |
G |
14: 68,037,803 (GRCm39) |
S947P |
probably benign |
Het |
| Dpysl2 |
G |
T |
14: 67,052,498 (GRCm39) |
A339D |
possibly damaging |
Het |
| Ebf2 |
A |
G |
14: 67,647,531 (GRCm39) |
D360G |
probably damaging |
Het |
| Ensa |
T |
C |
3: 95,532,489 (GRCm39) |
|
probably null |
Het |
| Fap |
C |
A |
2: 62,374,713 (GRCm39) |
V229F |
probably damaging |
Het |
| Fbn1 |
C |
A |
2: 125,163,155 (GRCm39) |
G2116* |
probably null |
Het |
| Frmd4b |
A |
T |
6: 97,272,822 (GRCm39) |
S857T |
probably damaging |
Het |
| Fsip2 |
T |
A |
2: 82,818,044 (GRCm39) |
Y4592* |
probably null |
Het |
| Fubp1 |
T |
A |
3: 151,928,966 (GRCm39) |
Y135N |
possibly damaging |
Het |
| Gdap2 |
T |
C |
3: 100,078,234 (GRCm39) |
L66P |
probably damaging |
Het |
| Gm10257 |
T |
C |
13: 101,083,305 (GRCm39) |
|
noncoding transcript |
Het |
| Gm1758 |
A |
T |
16: 14,325,036 (GRCm39) |
|
noncoding transcript |
Het |
| Gna13 |
T |
C |
11: 109,254,455 (GRCm39) |
|
probably benign |
Het |
| H2bc13 |
T |
C |
13: 21,900,088 (GRCm39) |
S76G |
probably benign |
Het |
| Heatr1 |
T |
C |
13: 12,446,718 (GRCm39) |
I1689T |
probably benign |
Het |
| Hephl1 |
A |
G |
9: 15,009,286 (GRCm39) |
I102T |
probably benign |
Het |
| Hltf |
T |
G |
3: 20,118,114 (GRCm39) |
Y121D |
possibly damaging |
Het |
| Hspg2 |
T |
C |
4: 137,256,784 (GRCm39) |
V1509A |
possibly damaging |
Het |
| Ifitm5 |
G |
T |
7: 140,530,077 (GRCm39) |
R16S |
probably benign |
Het |
| Kalrn |
C |
T |
16: 33,810,180 (GRCm39) |
D2525N |
possibly damaging |
Het |
| Kcna6 |
T |
C |
6: 126,715,519 (GRCm39) |
I457V |
probably damaging |
Het |
| Kctd17 |
T |
A |
15: 78,317,224 (GRCm39) |
L47Q |
probably damaging |
Het |
| Kdm1b |
C |
T |
13: 47,216,553 (GRCm39) |
R308W |
probably damaging |
Het |
| Klk14 |
G |
A |
7: 43,341,501 (GRCm39) |
C51Y |
probably damaging |
Het |
| Lrrc63 |
A |
G |
14: 75,363,601 (GRCm39) |
S177P |
possibly damaging |
Het |
| Lrriq1 |
T |
C |
10: 103,006,327 (GRCm39) |
D1266G |
probably benign |
Het |
| Map3k2 |
G |
T |
18: 32,361,203 (GRCm39) |
M554I |
probably damaging |
Het |
| Mst1r |
T |
A |
9: 107,797,124 (GRCm39) |
V1331E |
probably damaging |
Het |
| Musk |
T |
C |
4: 58,373,400 (GRCm39) |
I775T |
probably damaging |
Het |
| Mybl2 |
A |
G |
2: 162,916,683 (GRCm39) |
K7E |
probably damaging |
Het |
| Nf1 |
T |
C |
11: 79,338,398 (GRCm39) |
S1137P |
probably damaging |
Het |
| Nlrp5 |
A |
G |
7: 23,117,055 (GRCm39) |
I260V |
probably damaging |
Het |
| Or13c7 |
A |
T |
4: 43,854,323 (GRCm39) |
N5Y |
probably benign |
Het |
| Or9g4 |
A |
C |
2: 85,504,842 (GRCm39) |
Y218D |
probably damaging |
Het |
| Or9s23 |
G |
T |
1: 92,501,207 (GRCm39) |
A105S |
possibly damaging |
Het |
| Pabpc1l |
C |
T |
2: 163,869,542 (GRCm39) |
A114V |
possibly damaging |
Het |
| Plac8l1 |
T |
A |
18: 42,311,973 (GRCm39) |
I149F |
possibly damaging |
Het |
| Pou6f1 |
T |
A |
15: 100,476,293 (GRCm39) |
N531I |
probably damaging |
Het |
| Prdm10 |
A |
G |
9: 31,264,701 (GRCm39) |
Y712C |
probably damaging |
Het |
| Ptbp3 |
T |
C |
4: 59,514,297 (GRCm39) |
T43A |
possibly damaging |
Het |
| Ptpn13 |
T |
C |
5: 103,730,644 (GRCm39) |
|
probably null |
Het |
| Rnf135 |
T |
C |
11: 80,087,775 (GRCm39) |
|
probably null |
Het |
| Rusf1 |
A |
T |
7: 127,887,374 (GRCm39) |
|
probably benign |
Het |
| Serpinb3d |
A |
G |
1: 107,005,951 (GRCm39) |
L379P |
probably damaging |
Het |
| Sh2d6 |
T |
A |
6: 72,494,581 (GRCm39) |
T124S |
probably benign |
Het |
| Slc26a5 |
G |
A |
5: 22,042,992 (GRCm39) |
P153S |
probably damaging |
Het |
| Slc5a7 |
A |
G |
17: 54,588,822 (GRCm39) |
F275S |
possibly damaging |
Het |
| Snx14 |
A |
G |
9: 88,276,495 (GRCm39) |
S606P |
probably damaging |
Het |
| Sphkap |
A |
T |
1: 83,255,805 (GRCm39) |
I648K |
possibly damaging |
Het |
| Spon2 |
T |
C |
5: 33,371,904 (GRCm39) |
T301A |
probably damaging |
Het |
| Srpra |
C |
T |
9: 35,124,447 (GRCm39) |
T48I |
probably benign |
Het |
| Taar9 |
G |
A |
10: 23,985,408 (GRCm39) |
P9S |
probably benign |
Het |
| Tacc1 |
A |
T |
8: 25,672,405 (GRCm39) |
S274R |
possibly damaging |
Het |
| Tc2n |
A |
G |
12: 101,617,376 (GRCm39) |
S348P |
possibly damaging |
Het |
| Timd2 |
G |
T |
11: 46,578,008 (GRCm39) |
T41K |
probably damaging |
Het |
| Tmem132a |
T |
A |
19: 10,842,857 (GRCm39) |
E206V |
probably damaging |
Het |
| Tmt1a3 |
A |
G |
15: 100,232,889 (GRCm39) |
M27V |
probably benign |
Het |
| Tpi1 |
A |
T |
6: 124,789,544 (GRCm39) |
|
probably benign |
Het |
| Traf5 |
T |
G |
1: 191,729,765 (GRCm39) |
T429P |
probably benign |
Het |
| Trav4-3 |
A |
G |
14: 53,836,615 (GRCm39) |
S27G |
possibly damaging |
Het |
| Tubd1 |
T |
C |
11: 86,457,895 (GRCm39) |
M462T |
probably benign |
Het |
| Ube4a |
T |
C |
9: 44,860,120 (GRCm39) |
D314G |
probably damaging |
Het |
| Utp25 |
T |
A |
1: 192,796,116 (GRCm39) |
Q50L |
probably null |
Het |
| Vmn2r58 |
G |
T |
7: 41,514,495 (GRCm39) |
T158K |
probably damaging |
Het |
| Vmn2r68 |
C |
A |
7: 84,883,648 (GRCm39) |
M152I |
probably benign |
Het |
| Vmn2r91 |
A |
G |
17: 18,325,658 (GRCm39) |
E92G |
probably damaging |
Het |
| Wdr20rt |
T |
C |
12: 65,273,395 (GRCm39) |
V113A |
probably damaging |
Het |
| Zfp729a |
T |
C |
13: 67,768,546 (GRCm39) |
H561R |
probably damaging |
Het |
| Zfp804a |
T |
A |
2: 82,066,186 (GRCm39) |
D52E |
probably damaging |
Het |
|
| Other mutations in Il1rap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00402:Il1rap
|
APN |
16 |
26,541,151 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL00976:Il1rap
|
APN |
16 |
26,517,589 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01075:Il1rap
|
APN |
16 |
26,498,987 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01665:Il1rap
|
APN |
16 |
26,541,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01962:Il1rap
|
APN |
16 |
26,529,318 (GRCm39) |
nonsense |
probably null |
|
|
IGL02101:Il1rap
|
APN |
16 |
26,442,932 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02411:Il1rap
|
APN |
16 |
26,529,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03132:Il1rap
|
APN |
16 |
26,498,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
bacchus
|
UTSW |
16 |
26,529,382 (GRCm39) |
critical splice donor site |
probably null |
|
|
I1329:Il1rap
|
UTSW |
16 |
26,511,600 (GRCm39) |
missense |
probably benign |
0.07 |
|
LCD18:Il1rap
|
UTSW |
16 |
26,450,343 (GRCm39) |
intron |
probably benign |
|
|
PIT1430001:Il1rap
|
UTSW |
16 |
26,529,343 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0302:Il1rap
|
UTSW |
16 |
26,511,544 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0454:Il1rap
|
UTSW |
16 |
26,517,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0481:Il1rap
|
UTSW |
16 |
26,511,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0612:Il1rap
|
UTSW |
16 |
26,519,855 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R0765:Il1rap
|
UTSW |
16 |
26,529,382 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1552:Il1rap
|
UTSW |
16 |
26,541,184 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1801:Il1rap
|
UTSW |
16 |
26,517,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1867:Il1rap
|
UTSW |
16 |
26,541,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1942:Il1rap
|
UTSW |
16 |
26,541,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1996:Il1rap
|
UTSW |
16 |
26,541,243 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2118:Il1rap
|
UTSW |
16 |
26,529,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Il1rap
|
UTSW |
16 |
26,529,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2124:Il1rap
|
UTSW |
16 |
26,529,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Il1rap
|
UTSW |
16 |
26,541,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3105:Il1rap
|
UTSW |
16 |
26,541,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3106:Il1rap
|
UTSW |
16 |
26,541,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3891:Il1rap
|
UTSW |
16 |
26,495,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4133:Il1rap
|
UTSW |
16 |
26,541,636 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4409:Il1rap
|
UTSW |
16 |
26,531,015 (GRCm39) |
splice site |
probably null |
|
|
R4610:Il1rap
|
UTSW |
16 |
26,533,526 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4755:Il1rap
|
UTSW |
16 |
26,541,532 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4776:Il1rap
|
UTSW |
16 |
26,511,549 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4811:Il1rap
|
UTSW |
16 |
26,519,988 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4834:Il1rap
|
UTSW |
16 |
26,495,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5119:Il1rap
|
UTSW |
16 |
26,442,949 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5744:Il1rap
|
UTSW |
16 |
26,498,974 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6108:Il1rap
|
UTSW |
16 |
26,541,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6149:Il1rap
|
UTSW |
16 |
26,530,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Il1rap
|
UTSW |
16 |
26,529,256 (GRCm39) |
missense |
probably benign |
0.24 |
|
R6246:Il1rap
|
UTSW |
16 |
26,533,631 (GRCm39) |
missense |
probably benign |
|
|
R6249:Il1rap
|
UTSW |
16 |
26,511,598 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6254:Il1rap
|
UTSW |
16 |
26,514,020 (GRCm39) |
missense |
probably benign |
|
|
R6748:Il1rap
|
UTSW |
16 |
26,541,106 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7151:Il1rap
|
UTSW |
16 |
26,530,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7794:Il1rap
|
UTSW |
16 |
26,541,658 (GRCm39) |
missense |
probably benign |
|
|
R7818:Il1rap
|
UTSW |
16 |
26,517,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7819:Il1rap
|
UTSW |
16 |
26,541,151 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7863:Il1rap
|
UTSW |
16 |
26,495,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8240:Il1rap
|
UTSW |
16 |
26,520,001 (GRCm39) |
missense |
probably benign |
|
|
R8559:Il1rap
|
UTSW |
16 |
26,530,884 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8934:Il1rap
|
UTSW |
16 |
26,495,734 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8986:Il1rap
|
UTSW |
16 |
26,533,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9261:Il1rap
|
UTSW |
16 |
26,541,724 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9286:Il1rap
|
UTSW |
16 |
26,517,604 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9326:Il1rap
|
UTSW |
16 |
26,495,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9408:Il1rap
|
UTSW |
16 |
26,533,675 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9493:Il1rap
|
UTSW |
16 |
26,541,702 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9723:Il1rap
|
UTSW |
16 |
26,442,907 (GRCm39) |
start codon destroyed |
probably null |
0.97 |
|
X0027:Il1rap
|
UTSW |
16 |
26,519,897 (GRCm39) |
missense |
probably benign |
0.20 |
|
X0028:Il1rap
|
UTSW |
16 |
26,495,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Il1rap
|
UTSW |
16 |
26,541,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGCACAAGTTCCATGTTAGC -3'
(R):5'- TGGTCCTTACGTGCTGTAGC -3'
Sequencing Primer
(F):5'- GCACAAGTTCCATGTTAGCACTAAG -3'
(R):5'- ACGTGCTGTAGCTTTTGATCATGC -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation