Incidental Mutation 'R4795:Pde4d'
| ID |
368970 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pde4d
|
| Ensembl Gene |
ENSMUSG00000021699 |
| Gene Name |
phosphodiesterase 4D, cAMP specific |
| Synonyms |
9630011N22Rik, dunce, Dpde3 |
| MMRRC Submission |
041996-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4795 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
108790711-110092503 bp(+) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
T to A
at 110074705 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136485
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074103]
[ENSMUST00000079975]
[ENSMUST00000117420]
[ENSMUST00000117879]
[ENSMUST00000119507]
[ENSMUST00000119672]
[ENSMUST00000120664]
[ENSMUST00000120671]
[ENSMUST00000177907]
[ENSMUST00000122041]
[ENSMUST00000135275]
|
| AlphaFold |
Q01063 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074103
|
| SMART Domains |
Protein: ENSMUSP00000073742
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
18 |
N/A |
INTRINSIC |
|
HDc
|
329 |
504 |
1.12e-2 |
SMART |
|
low complexity region
|
652 |
667 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000079975
|
| SMART Domains |
Protein: ENSMUSP00000078891
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
349 |
524 |
1.12e-2 |
SMART |
|
low complexity region
|
672 |
687 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117420
|
| SMART Domains |
Protein: ENSMUSP00000113610
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
168 |
343 |
1.12e-2 |
SMART |
|
low complexity region
|
491 |
506 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117879
|
| SMART Domains |
Protein: ENSMUSP00000112774
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
155 |
330 |
1.12e-2 |
SMART |
|
low complexity region
|
478 |
493 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119507
|
| SMART Domains |
Protein: ENSMUSP00000114089
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
354 |
529 |
1.12e-2 |
SMART |
|
low complexity region
|
677 |
692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119672
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000120664
|
| SMART Domains |
Protein: ENSMUSP00000113024
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
235 |
410 |
1.12e-2 |
SMART |
|
low complexity region
|
558 |
573 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151429
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000120671
|
| SMART Domains |
Protein: ENSMUSP00000112991
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
45 |
84 |
N/A |
INTRINSIC |
|
HDc
|
454 |
629 |
1.12e-2 |
SMART |
|
low complexity region
|
777 |
792 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177907
|
| SMART Domains |
Protein: ENSMUSP00000136485
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
398 |
573 |
1.12e-2 |
SMART |
|
low complexity region
|
721 |
736 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122041
|
| SMART Domains |
Protein: ENSMUSP00000113488
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
HDc
|
398 |
573 |
1.12e-2 |
SMART |
|
low complexity region
|
721 |
736 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135275
|
| SMART Domains |
Protein: ENSMUSP00000119583
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
HDc
|
351 |
526 |
1.12e-2 |
SMART |
|
low complexity region
|
674 |
689 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153234
|
| SMART Domains |
Protein: ENSMUSP00000121592
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1E9K|A
|
22 |
59 |
9e-18 |
PDB |
|
low complexity region
|
69 |
85 |
N/A |
INTRINSIC |
|
HDc
|
405 |
580 |
1.12e-2 |
SMART |
|
low complexity region
|
728 |
743 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155459
|
| SMART Domains |
Protein: ENSMUSP00000114945
Gene: ENSMUSG00000021699
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PDEase_I
|
121 |
189 |
2.6e-23 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.7%
|
| Validation Efficiency |
98% (123/125) |
| MGI Phenotype |
PHENOTYPE: Homozygotes for targeted null mutations exhibit delayed growth, female infertility associated with impaired ovulation, and reduced postnatal viability. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca4 |
T |
G |
3: 121,969,772 (GRCm39) |
L2259R |
probably damaging |
Het |
| Acd |
A |
G |
8: 106,427,647 (GRCm39) |
S2P |
possibly damaging |
Het |
| Acsf3 |
A |
G |
8: 123,506,896 (GRCm39) |
Y63C |
possibly damaging |
Het |
| Adam21 |
T |
C |
12: 81,607,748 (GRCm39) |
I5V |
probably benign |
Het |
| Adamts6 |
C |
A |
13: 104,580,636 (GRCm39) |
S783* |
probably null |
Het |
| Adamtsl1 |
T |
C |
4: 86,162,006 (GRCm39) |
|
probably null |
Het |
| Adck2 |
T |
A |
6: 39,553,327 (GRCm39) |
S313T |
probably benign |
Het |
| Adgb |
A |
G |
10: 10,233,616 (GRCm39) |
I1285T |
probably benign |
Het |
| Angptl1 |
T |
A |
1: 156,688,153 (GRCm39) |
M485K |
possibly damaging |
Het |
| Ank3 |
G |
A |
10: 69,694,095 (GRCm39) |
V289I |
probably benign |
Het |
| Atp13a4 |
A |
G |
16: 29,308,826 (GRCm39) |
|
probably null |
Het |
| Atp1a1 |
A |
G |
3: 101,491,091 (GRCm39) |
L648P |
probably benign |
Het |
| Atp2a3 |
A |
G |
11: 72,863,855 (GRCm39) |
I194V |
probably benign |
Het |
| Bglap |
A |
C |
3: 88,291,712 (GRCm39) |
I4S |
unknown |
Het |
| Cacna1b |
T |
A |
2: 24,527,499 (GRCm39) |
T1621S |
possibly damaging |
Het |
| Ccdc112 |
T |
A |
18: 46,420,739 (GRCm39) |
Q337L |
probably benign |
Het |
| Ccdc121rt3 |
A |
G |
5: 112,503,165 (GRCm39) |
S180P |
possibly damaging |
Het |
| Cd34 |
T |
G |
1: 194,633,319 (GRCm39) |
S194A |
probably damaging |
Het |
| Cdh20 |
A |
G |
1: 104,868,989 (GRCm39) |
D160G |
probably damaging |
Het |
| Clock |
T |
C |
5: 76,413,763 (GRCm39) |
K44R |
probably damaging |
Het |
| Commd9 |
A |
G |
2: 101,729,241 (GRCm39) |
N116D |
probably benign |
Het |
| Dab2 |
C |
A |
15: 6,459,092 (GRCm39) |
P335T |
probably benign |
Het |
| Epb41l3 |
T |
A |
17: 69,555,714 (GRCm39) |
|
probably null |
Het |
| Epha2 |
A |
G |
4: 141,049,727 (GRCm39) |
|
probably null |
Het |
| Fam78b |
T |
C |
1: 166,906,216 (GRCm39) |
V125A |
probably benign |
Het |
| Fars2 |
A |
T |
13: 36,721,400 (GRCm39) |
E448V |
probably damaging |
Het |
| Fkbpl |
G |
A |
17: 34,864,303 (GRCm39) |
A24T |
probably benign |
Het |
| Glyr1 |
A |
C |
16: 4,865,622 (GRCm39) |
V44G |
probably benign |
Het |
| Gm1527 |
A |
G |
3: 28,974,812 (GRCm39) |
I542V |
possibly damaging |
Het |
| Gm18856 |
C |
A |
13: 14,139,793 (GRCm39) |
|
probably benign |
Het |
| Gm44501 |
A |
G |
17: 40,889,605 (GRCm39) |
K40E |
probably benign |
Het |
| Hdhd5 |
T |
C |
6: 120,500,407 (GRCm39) |
H97R |
probably benign |
Het |
| Hmcn1 |
A |
G |
1: 150,629,362 (GRCm39) |
V965A |
probably benign |
Het |
| Hsf5 |
A |
G |
11: 87,526,446 (GRCm39) |
M373V |
probably benign |
Het |
| Igbp1b |
C |
T |
6: 138,634,803 (GRCm39) |
E214K |
probably benign |
Het |
| Iigp1 |
T |
A |
18: 60,522,964 (GRCm39) |
F27L |
probably benign |
Het |
| Isl1 |
T |
C |
13: 116,441,966 (GRCm39) |
N89S |
probably benign |
Het |
| Itga1 |
C |
A |
13: 115,171,921 (GRCm39) |
W61C |
probably damaging |
Het |
| Itga5 |
T |
C |
15: 103,256,187 (GRCm39) |
R922G |
probably benign |
Het |
| Kbtbd3 |
G |
A |
9: 4,331,073 (GRCm39) |
W482* |
probably null |
Het |
| Kcnq1 |
A |
G |
7: 142,736,494 (GRCm39) |
T168A |
probably benign |
Het |
| Lrch3 |
A |
G |
16: 32,826,074 (GRCm39) |
N631S |
probably damaging |
Het |
| Lrrk1 |
T |
A |
7: 65,912,413 (GRCm39) |
I1716F |
possibly damaging |
Het |
| Ly75 |
T |
C |
2: 60,180,284 (GRCm39) |
E631G |
probably benign |
Het |
| Map4 |
T |
C |
9: 109,864,331 (GRCm39) |
S519P |
probably benign |
Het |
| Mroh2a |
A |
G |
1: 88,186,386 (GRCm39) |
S64G |
probably benign |
Het |
| Mrtfa |
C |
T |
15: 80,901,234 (GRCm39) |
S419N |
probably damaging |
Het |
| Muc5b |
A |
G |
7: 141,403,304 (GRCm39) |
E755G |
unknown |
Het |
| Ncaph2 |
T |
G |
15: 89,255,010 (GRCm39) |
V478G |
probably damaging |
Het |
| Ncbp1 |
A |
G |
4: 46,152,967 (GRCm39) |
R247G |
possibly damaging |
Het |
| Necab1 |
G |
T |
4: 15,111,208 (GRCm39) |
D73E |
possibly damaging |
Het |
| Nedd9 |
T |
C |
13: 41,471,376 (GRCm39) |
K208E |
probably benign |
Het |
| Nfyb |
A |
T |
10: 82,588,202 (GRCm39) |
|
probably benign |
Het |
| Nol4 |
T |
C |
18: 23,054,944 (GRCm39) |
Q162R |
probably damaging |
Het |
| Nwd2 |
G |
A |
5: 63,962,776 (GRCm39) |
D787N |
probably benign |
Het |
| Olfr908 |
T |
A |
9: 38,427,799 (GRCm39) |
M157K |
probably damaging |
Het |
| Or10a5 |
A |
T |
7: 106,636,121 (GRCm39) |
Y253F |
probably benign |
Het |
| Or11g7 |
A |
C |
14: 50,690,874 (GRCm39) |
M122L |
probably damaging |
Het |
| Or13a22 |
A |
G |
7: 140,072,920 (GRCm39) |
D123G |
probably damaging |
Het |
| Or5ac23 |
C |
T |
16: 59,149,213 (GRCm39) |
V220I |
probably benign |
Het |
| Or6a2 |
C |
T |
7: 106,600,542 (GRCm39) |
G175D |
probably damaging |
Het |
| Or6e1 |
A |
G |
14: 54,520,004 (GRCm39) |
M116T |
probably damaging |
Het |
| Orai3 |
T |
C |
7: 127,373,060 (GRCm39) |
V187A |
probably benign |
Het |
| Parn |
T |
C |
16: 13,424,066 (GRCm39) |
T444A |
probably benign |
Het |
| Pcdh11x |
A |
C |
X: 119,309,937 (GRCm39) |
N460T |
probably damaging |
Het |
| Pcnt |
C |
T |
10: 76,205,858 (GRCm39) |
R2516H |
probably benign |
Het |
| Pdgfra |
A |
G |
5: 75,349,972 (GRCm39) |
N952S |
probably benign |
Het |
| Pgm2 |
A |
G |
5: 64,261,217 (GRCm39) |
Y237C |
probably damaging |
Het |
| Plcb2 |
A |
G |
2: 118,541,605 (GRCm39) |
V975A |
probably benign |
Het |
| Polk |
T |
C |
13: 96,625,764 (GRCm39) |
T347A |
probably benign |
Het |
| Ppp6r1 |
C |
T |
7: 4,644,053 (GRCm39) |
V430M |
possibly damaging |
Het |
| Ptges2 |
C |
A |
2: 32,286,334 (GRCm39) |
C16* |
probably null |
Het |
| Relb |
A |
T |
7: 19,353,764 (GRCm39) |
I38N |
probably damaging |
Het |
| Runx1t1 |
T |
A |
4: 13,837,767 (GRCm39) |
N51K |
probably damaging |
Het |
| Samsn1 |
A |
G |
16: 75,680,733 (GRCm39) |
|
probably benign |
Het |
| Scrn1 |
A |
G |
6: 54,497,754 (GRCm39) |
V279A |
possibly damaging |
Het |
| Sec31b |
A |
G |
19: 44,520,185 (GRCm39) |
S200P |
probably benign |
Het |
| Selp |
A |
G |
1: 163,972,475 (GRCm39) |
T705A |
probably benign |
Het |
| Slc2a1 |
G |
A |
4: 118,989,642 (GRCm39) |
R61Q |
probably damaging |
Het |
| Slit3 |
G |
A |
11: 35,542,647 (GRCm39) |
|
probably null |
Het |
| Smo |
T |
A |
6: 29,755,573 (GRCm39) |
V415E |
probably damaging |
Het |
| Spag8 |
C |
A |
4: 43,652,035 (GRCm39) |
V350L |
possibly damaging |
Het |
| Tbck |
T |
G |
3: 132,413,559 (GRCm39) |
L132R |
possibly damaging |
Het |
| Thnsl1 |
T |
A |
2: 21,216,856 (GRCm39) |
C203* |
probably null |
Het |
| Tm9sf2 |
T |
A |
14: 122,387,252 (GRCm39) |
|
probably null |
Het |
| Tmem131 |
A |
G |
1: 36,880,757 (GRCm39) |
V171A |
probably damaging |
Het |
| Tmem209 |
T |
C |
6: 30,501,954 (GRCm39) |
T83A |
probably benign |
Het |
| Tmem63a |
T |
C |
1: 180,782,416 (GRCm39) |
Y138H |
probably damaging |
Het |
| Trim80 |
A |
G |
11: 115,338,769 (GRCm39) |
Y533C |
probably damaging |
Het |
| Trpv2 |
A |
G |
11: 62,472,006 (GRCm39) |
D66G |
possibly damaging |
Het |
| Trrap |
T |
A |
5: 144,769,298 (GRCm39) |
I2620N |
probably benign |
Het |
| Ttyh3 |
A |
T |
5: 140,620,541 (GRCm39) |
I232N |
probably damaging |
Het |
| Ube2dnl1 |
G |
A |
X: 113,815,482 (GRCm39) |
C119Y |
possibly damaging |
Het |
| Unc13c |
T |
A |
9: 73,839,469 (GRCm39) |
S461C |
probably damaging |
Het |
| Unc80 |
T |
G |
1: 66,567,100 (GRCm39) |
I902S |
probably damaging |
Het |
| Usp42 |
C |
A |
5: 143,709,692 (GRCm39) |
G170W |
probably damaging |
Het |
| Vldlr |
T |
C |
19: 27,216,252 (GRCm39) |
|
probably null |
Het |
| Ywhab |
A |
G |
2: 163,857,265 (GRCm39) |
Y180C |
probably damaging |
Het |
| Zan |
A |
T |
5: 137,379,112 (GRCm39) |
C5329* |
probably null |
Het |
| Zbtb40 |
C |
T |
4: 136,725,953 (GRCm39) |
M535I |
probably benign |
Het |
| Zdhhc1 |
CGGGGG |
CGGGGGG |
8: 106,210,376 (GRCm39) |
|
probably null |
Het |
| Zfp318 |
A |
G |
17: 46,722,988 (GRCm39) |
T1664A |
probably benign |
Het |
| Zfp7 |
T |
A |
15: 76,775,546 (GRCm39) |
C529* |
probably null |
Het |
| Zfp768 |
T |
C |
7: 126,942,547 (GRCm39) |
Q527R |
possibly damaging |
Het |
| Zfp975 |
T |
A |
7: 42,314,570 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Pde4d |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00465:Pde4d
|
APN |
13 |
110,073,221 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL00792:Pde4d
|
APN |
13 |
110,071,929 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL01014:Pde4d
|
APN |
13 |
110,086,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01660:Pde4d
|
APN |
13 |
110,074,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02233:Pde4d
|
APN |
13 |
109,877,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02405:Pde4d
|
APN |
13 |
108,996,743 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02544:Pde4d
|
APN |
13 |
109,877,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02885:Pde4d
|
APN |
13 |
110,084,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03286:Pde4d
|
APN |
13 |
110,091,040 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03406:Pde4d
|
APN |
13 |
110,091,125 (GRCm39) |
unclassified |
probably benign |
|
|
Heliosphere
|
UTSW |
13 |
109,253,476 (GRCm39) |
missense |
probably benign |
|
|
Stubbs
|
UTSW |
13 |
109,909,256 (GRCm39) |
intron |
probably benign |
|
|
IGL03055:Pde4d
|
UTSW |
13 |
110,071,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0020:Pde4d
|
UTSW |
13 |
110,091,104 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0020:Pde4d
|
UTSW |
13 |
110,091,104 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0054:Pde4d
|
UTSW |
13 |
109,876,955 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0054:Pde4d
|
UTSW |
13 |
109,876,955 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0357:Pde4d
|
UTSW |
13 |
110,087,802 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0482:Pde4d
|
UTSW |
13 |
110,073,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0689:Pde4d
|
UTSW |
13 |
109,877,078 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0884:Pde4d
|
UTSW |
13 |
110,087,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1169:Pde4d
|
UTSW |
13 |
110,087,462 (GRCm39) |
splice site |
probably null |
|
|
R1225:Pde4d
|
UTSW |
13 |
110,086,755 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1246:Pde4d
|
UTSW |
13 |
110,087,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1344:Pde4d
|
UTSW |
13 |
110,086,921 (GRCm39) |
nonsense |
probably null |
|
|
R1351:Pde4d
|
UTSW |
13 |
110,087,809 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1371:Pde4d
|
UTSW |
13 |
109,253,595 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1418:Pde4d
|
UTSW |
13 |
110,086,921 (GRCm39) |
nonsense |
probably null |
|
|
R2197:Pde4d
|
UTSW |
13 |
110,084,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2440:Pde4d
|
UTSW |
13 |
110,063,731 (GRCm39) |
intron |
probably benign |
|
|
R3114:Pde4d
|
UTSW |
13 |
110,084,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3115:Pde4d
|
UTSW |
13 |
110,084,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3722:Pde4d
|
UTSW |
13 |
110,087,866 (GRCm39) |
nonsense |
probably null |
|
|
R3742:Pde4d
|
UTSW |
13 |
109,877,013 (GRCm39) |
missense |
probably benign |
0.42 |
|
R3797:Pde4d
|
UTSW |
13 |
109,769,431 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3983:Pde4d
|
UTSW |
13 |
109,876,940 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4618:Pde4d
|
UTSW |
13 |
110,070,411 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4768:Pde4d
|
UTSW |
13 |
110,070,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Pde4d
|
UTSW |
13 |
109,253,400 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4942:Pde4d
|
UTSW |
13 |
108,996,733 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4984:Pde4d
|
UTSW |
13 |
109,876,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Pde4d
|
UTSW |
13 |
109,877,007 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5267:Pde4d
|
UTSW |
13 |
109,397,343 (GRCm39) |
intron |
probably benign |
|
|
R5311:Pde4d
|
UTSW |
13 |
109,769,399 (GRCm39) |
missense |
probably benign |
|
|
R5311:Pde4d
|
UTSW |
13 |
109,769,398 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5376:Pde4d
|
UTSW |
13 |
109,909,178 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5551:Pde4d
|
UTSW |
13 |
110,084,930 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5753:Pde4d
|
UTSW |
13 |
109,909,256 (GRCm39) |
intron |
probably benign |
|
|
R5754:Pde4d
|
UTSW |
13 |
110,074,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5838:Pde4d
|
UTSW |
13 |
109,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5864:Pde4d
|
UTSW |
13 |
110,074,582 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6039:Pde4d
|
UTSW |
13 |
110,084,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6039:Pde4d
|
UTSW |
13 |
110,084,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Pde4d
|
UTSW |
13 |
109,169,119 (GRCm39) |
nonsense |
probably null |
|
|
R6214:Pde4d
|
UTSW |
13 |
110,085,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6215:Pde4d
|
UTSW |
13 |
110,085,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6273:Pde4d
|
UTSW |
13 |
110,086,755 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6431:Pde4d
|
UTSW |
13 |
109,738,320 (GRCm39) |
splice site |
probably null |
|
|
R6501:Pde4d
|
UTSW |
13 |
109,253,476 (GRCm39) |
missense |
probably benign |
|
|
R6534:Pde4d
|
UTSW |
13 |
109,769,435 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6709:Pde4d
|
UTSW |
13 |
110,084,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6722:Pde4d
|
UTSW |
13 |
109,769,432 (GRCm39) |
nonsense |
probably null |
|
|
R7164:Pde4d
|
UTSW |
13 |
109,169,222 (GRCm39) |
missense |
probably benign |
|
|
R7222:Pde4d
|
UTSW |
13 |
109,894,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7417:Pde4d
|
UTSW |
13 |
109,769,322 (GRCm39) |
splice site |
probably null |
|
|
R7489:Pde4d
|
UTSW |
13 |
109,253,301 (GRCm39) |
missense |
unknown |
|
|
R7563:Pde4d
|
UTSW |
13 |
110,087,541 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7861:Pde4d
|
UTSW |
13 |
110,071,858 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8167:Pde4d
|
UTSW |
13 |
109,578,855 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8197:Pde4d
|
UTSW |
13 |
110,084,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Pde4d
|
UTSW |
13 |
108,996,722 (GRCm39) |
missense |
probably benign |
|
|
R8715:Pde4d
|
UTSW |
13 |
110,071,876 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8926:Pde4d
|
UTSW |
13 |
110,074,625 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9054:Pde4d
|
UTSW |
13 |
110,071,924 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9406:Pde4d
|
UTSW |
13 |
109,877,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9516:Pde4d
|
UTSW |
13 |
109,397,196 (GRCm39) |
missense |
|
|
|
R9526:Pde4d
|
UTSW |
13 |
110,071,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCCCAGTAGACACTTTGATTACG -3'
(R):5'- CCGGAAGTCAGTATGTGAGATG -3'
Sequencing Primer
(F):5'- CGTATCTTATGACTCTGGAAGACC -3'
(R):5'- CCCACTGGATCATTTCAGAGAAGTG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation