Incidental Mutation 'R4796:Plxnb1'
| ID |
369063 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4796 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 108943663 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Leucine
at position 1917
(V1917L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072093
AA Change: V1917L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: V1917L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrv1 |
C |
T |
13: 81,303,350 (GRCm39) |
W132* |
probably null |
Het |
| Atp8b3 |
A |
G |
10: 80,360,188 (GRCm39) |
V961A |
probably damaging |
Het |
| Bglap |
A |
C |
3: 88,291,712 (GRCm39) |
I4S |
unknown |
Het |
| Bmp1 |
T |
C |
14: 70,729,513 (GRCm39) |
|
probably null |
Het |
| Brd10 |
G |
A |
19: 29,731,018 (GRCm39) |
H665Y |
probably benign |
Het |
| Btaf1 |
T |
C |
19: 36,933,828 (GRCm39) |
L152P |
possibly damaging |
Het |
| Cacna1b |
T |
A |
2: 24,527,499 (GRCm39) |
T1621S |
possibly damaging |
Het |
| Capn3 |
A |
T |
2: 120,333,479 (GRCm39) |
N621I |
probably damaging |
Het |
| Ccdc121rt3 |
A |
G |
5: 112,503,165 (GRCm39) |
S180P |
possibly damaging |
Het |
| Ccdc59 |
T |
C |
10: 105,677,429 (GRCm39) |
S23P |
probably benign |
Het |
| Cd22 |
A |
T |
7: 30,572,381 (GRCm39) |
|
probably null |
Het |
| Cdh20 |
A |
G |
1: 104,868,989 (GRCm39) |
D160G |
probably damaging |
Het |
| Cep112 |
T |
C |
11: 108,377,818 (GRCm39) |
|
probably null |
Het |
| Clock |
T |
C |
5: 76,413,763 (GRCm39) |
K44R |
probably damaging |
Het |
| Coq10b |
A |
G |
1: 55,110,957 (GRCm39) |
T242A |
probably damaging |
Het |
| Cstdc2 |
A |
G |
2: 148,692,658 (GRCm39) |
F48S |
probably damaging |
Het |
| Ctnnd1 |
G |
T |
2: 84,450,270 (GRCm39) |
R317S |
probably damaging |
Het |
| Dlg5 |
G |
A |
14: 24,194,451 (GRCm39) |
H1674Y |
probably damaging |
Het |
| Drc3 |
C |
A |
11: 60,254,354 (GRCm39) |
N75K |
probably damaging |
Het |
| Efna4 |
T |
C |
3: 89,242,555 (GRCm39) |
E113G |
probably damaging |
Het |
| Egr3 |
C |
A |
14: 70,315,024 (GRCm39) |
A44D |
probably benign |
Het |
| Ercc3 |
T |
C |
18: 32,381,363 (GRCm39) |
F393S |
probably damaging |
Het |
| Evi2 |
T |
A |
11: 79,406,273 (GRCm39) |
|
probably benign |
Het |
| Fam78b |
T |
C |
1: 166,906,216 (GRCm39) |
V125A |
probably benign |
Het |
| Fars2 |
A |
T |
13: 36,721,400 (GRCm39) |
E448V |
probably damaging |
Het |
| Farsb |
A |
T |
1: 78,401,833 (GRCm39) |
*590R |
probably null |
Het |
| Fat3 |
A |
G |
9: 15,911,028 (GRCm39) |
M1658T |
probably benign |
Het |
| Fhod3 |
G |
T |
18: 25,118,358 (GRCm39) |
V232F |
probably damaging |
Het |
| Fkbpl |
G |
A |
17: 34,864,303 (GRCm39) |
A24T |
probably benign |
Het |
| Fzd3 |
A |
G |
14: 65,472,607 (GRCm39) |
V387A |
possibly damaging |
Het |
| Gm1527 |
A |
G |
3: 28,974,812 (GRCm39) |
I542V |
possibly damaging |
Het |
| Gm7964 |
A |
G |
7: 83,405,109 (GRCm39) |
|
probably null |
Het |
| Hbs1l |
G |
T |
10: 21,218,405 (GRCm39) |
G301C |
probably damaging |
Het |
| Hipk4 |
A |
G |
7: 27,227,995 (GRCm39) |
H247R |
probably benign |
Het |
| Hmcn1 |
A |
G |
1: 150,629,362 (GRCm39) |
V965A |
probably benign |
Het |
| Hoxa5 |
C |
T |
6: 52,180,943 (GRCm39) |
A130T |
probably benign |
Het |
| Igf2r |
C |
T |
17: 12,903,013 (GRCm39) |
V2346I |
possibly damaging |
Het |
| Igsf8 |
T |
C |
1: 172,143,889 (GRCm39) |
V14A |
probably benign |
Het |
| Impg1 |
G |
A |
9: 80,301,377 (GRCm39) |
P183L |
probably damaging |
Het |
| Isl1 |
T |
C |
13: 116,441,966 (GRCm39) |
N89S |
probably benign |
Het |
| Itga1 |
C |
A |
13: 115,171,921 (GRCm39) |
W61C |
probably damaging |
Het |
| Itga5 |
T |
C |
15: 103,256,187 (GRCm39) |
R922G |
probably benign |
Het |
| Itgb5 |
T |
C |
16: 33,705,391 (GRCm39) |
V227A |
possibly damaging |
Het |
| Jph4 |
G |
T |
14: 55,347,165 (GRCm39) |
P461T |
probably damaging |
Het |
| Kcnab1 |
T |
A |
3: 65,211,586 (GRCm39) |
|
probably null |
Het |
| Klrc1 |
T |
A |
6: 129,654,725 (GRCm39) |
|
probably null |
Het |
| Lonrf2 |
A |
T |
1: 38,855,119 (GRCm39) |
L92Q |
probably benign |
Het |
| Ly75 |
T |
C |
2: 60,180,284 (GRCm39) |
E631G |
probably benign |
Het |
| Mapk13 |
T |
C |
17: 28,994,528 (GRCm39) |
Y140H |
probably damaging |
Het |
| Meak7 |
A |
T |
8: 120,495,093 (GRCm39) |
S222T |
probably benign |
Het |
| Mgat4d |
A |
G |
8: 84,084,749 (GRCm39) |
E164G |
probably damaging |
Het |
| Mrtfa |
C |
T |
15: 80,901,234 (GRCm39) |
S419N |
probably damaging |
Het |
| Mtcl2 |
A |
G |
2: 156,862,172 (GRCm39) |
S1586P |
probably benign |
Het |
| Mthfs |
A |
T |
9: 89,122,078 (GRCm39) |
H188L |
probably benign |
Het |
| Muc5b |
T |
A |
7: 141,417,983 (GRCm39) |
M3643K |
possibly damaging |
Het |
| Mylk3 |
T |
C |
8: 86,077,014 (GRCm39) |
Y474C |
probably damaging |
Het |
| Myo5b |
A |
G |
18: 74,877,701 (GRCm39) |
T1567A |
possibly damaging |
Het |
| Ncaph2 |
T |
G |
15: 89,255,010 (GRCm39) |
V478G |
probably damaging |
Het |
| Ncbp1 |
A |
G |
4: 46,152,967 (GRCm39) |
R247G |
possibly damaging |
Het |
| Nedd9 |
T |
C |
13: 41,471,376 (GRCm39) |
K208E |
probably benign |
Het |
| Nxph2 |
C |
T |
2: 23,289,870 (GRCm39) |
T74M |
probably benign |
Het |
| Ogdh |
T |
A |
11: 6,290,570 (GRCm39) |
M385K |
probably benign |
Het |
| Or10a5 |
A |
T |
7: 106,636,121 (GRCm39) |
Y253F |
probably benign |
Het |
| Or3a1c |
A |
T |
11: 74,046,417 (GRCm39) |
I146F |
probably benign |
Het |
| Or4a2 |
T |
C |
2: 89,248,235 (GRCm39) |
H174R |
probably damaging |
Het |
| Or6a2 |
C |
T |
7: 106,600,542 (GRCm39) |
G175D |
probably damaging |
Het |
| Or7g18 |
T |
C |
9: 18,787,475 (GRCm39) |
V284A |
probably damaging |
Het |
| Or8b54 |
T |
A |
9: 38,686,670 (GRCm39) |
F40I |
probably benign |
Het |
| Pcsk2 |
A |
C |
2: 143,655,345 (GRCm39) |
I510L |
probably benign |
Het |
| Pdgfra |
A |
G |
5: 75,349,972 (GRCm39) |
N952S |
probably benign |
Het |
| Pex26 |
T |
C |
6: 121,170,516 (GRCm39) |
F287S |
probably damaging |
Het |
| Pick1 |
G |
C |
15: 79,139,810 (GRCm39) |
|
probably benign |
Het |
| Polk |
T |
C |
13: 96,625,764 (GRCm39) |
T347A |
probably benign |
Het |
| Ppp1r10 |
T |
G |
17: 36,234,979 (GRCm39) |
I61R |
probably damaging |
Het |
| Prex1 |
A |
T |
2: 166,434,211 (GRCm39) |
L503Q |
probably damaging |
Het |
| Ptp4a1 |
A |
C |
1: 30,983,019 (GRCm39) |
I133R |
probably damaging |
Het |
| Rassf10 |
G |
T |
7: 112,553,735 (GRCm39) |
R112L |
probably damaging |
Het |
| Ripor3 |
T |
A |
2: 167,823,260 (GRCm39) |
I884F |
probably damaging |
Het |
| Rnft2 |
A |
G |
5: 118,339,311 (GRCm39) |
Y369H |
probably damaging |
Het |
| Rtp3 |
A |
T |
9: 110,815,522 (GRCm39) |
V281E |
probably benign |
Het |
| Runx1t1 |
T |
A |
4: 13,837,767 (GRCm39) |
N51K |
probably damaging |
Het |
| Selp |
A |
G |
1: 163,972,475 (GRCm39) |
T705A |
probably benign |
Het |
| Sgca |
A |
T |
11: 94,861,553 (GRCm39) |
|
probably null |
Het |
| Slc22a3 |
T |
C |
17: 12,642,675 (GRCm39) |
E514G |
probably damaging |
Het |
| Slc28a2b |
T |
A |
2: 122,344,940 (GRCm39) |
I182N |
probably damaging |
Het |
| Slc2a1 |
G |
A |
4: 118,989,642 (GRCm39) |
R61Q |
probably damaging |
Het |
| Smarcal1 |
G |
A |
1: 72,636,599 (GRCm39) |
V425I |
probably benign |
Het |
| Ssx2ip |
T |
C |
3: 146,124,114 (GRCm39) |
V43A |
probably benign |
Het |
| Synpo |
A |
G |
18: 60,737,386 (GRCm39) |
S187P |
probably damaging |
Het |
| Thnsl1 |
T |
A |
2: 21,216,856 (GRCm39) |
C203* |
probably null |
Het |
| Ttyh3 |
A |
T |
5: 140,620,541 (GRCm39) |
I232N |
probably damaging |
Het |
| Upk1b |
T |
C |
16: 38,607,604 (GRCm39) |
H41R |
probably benign |
Het |
| Vmn2r76 |
T |
C |
7: 85,879,652 (GRCm39) |
D216G |
possibly damaging |
Het |
| Zan |
A |
T |
5: 137,379,112 (GRCm39) |
C5329* |
probably null |
Het |
| Zbtb40 |
C |
T |
4: 136,725,953 (GRCm39) |
M535I |
probably benign |
Het |
| Zfp383 |
A |
C |
7: 29,614,263 (GRCm39) |
T173P |
possibly damaging |
Het |
| Zfp7 |
T |
A |
15: 76,775,546 (GRCm39) |
C529* |
probably null |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1727:Plxnb1
|
UTSW |
9 |
108,930,125 (GRCm39) |
splice site |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2102:Plxnb1
|
UTSW |
9 |
108,944,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4676:Plxnb1
|
UTSW |
9 |
108,939,503 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Plxnb1
|
UTSW |
9 |
108,939,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Plxnb1
|
UTSW |
9 |
108,934,442 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5256:Plxnb1
|
UTSW |
9 |
108,943,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6193:Plxnb1
|
UTSW |
9 |
108,933,971 (GRCm39) |
missense |
probably benign |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCCTGAGATCTACCTGACACG -3'
(R):5'- TAACTGTGCTGTGGAGGCAG -3'
Sequencing Primer
(F):5'- ACGCCTGCTATCCATGAAGGTG -3'
(R):5'- AGGCCCCCACATATGTCCTG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation