Incidental Mutation 'R4798:Urb1'
| ID |
369264 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
5730405K23Rik, 4921511H13Rik |
| MMRRC Submission |
042422-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4798 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
90548415-90607301 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 90554715 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 1839
(N1839S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140920
AA Change: N1839S
PolyPhen 2
Score 0.124 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: N1839S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0639 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.6%
|
| Validation Efficiency |
97% (111/114) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
T |
C |
13: 77,471,843 (GRCm39) |
W1083R |
possibly damaging |
Het |
| Adamts10 |
T |
A |
17: 33,747,726 (GRCm39) |
L54Q |
probably damaging |
Het |
| Ankrd24 |
A |
C |
10: 81,479,149 (GRCm39) |
|
probably benign |
Het |
| Atg2b |
A |
G |
12: 105,618,888 (GRCm39) |
S813P |
probably benign |
Het |
| Atp13a3 |
T |
A |
16: 30,160,058 (GRCm39) |
I716F |
probably damaging |
Het |
| Atp6v1c1 |
T |
A |
15: 38,689,420 (GRCm39) |
W294R |
probably damaging |
Het |
| Atrnl1 |
G |
T |
19: 58,030,793 (GRCm39) |
A1312S |
probably benign |
Het |
| Bcl2 |
A |
T |
1: 106,640,338 (GRCm39) |
H91Q |
possibly damaging |
Het |
| Cacna1c |
G |
A |
6: 118,607,263 (GRCm39) |
Q1214* |
probably null |
Het |
| Cacna1g |
C |
A |
11: 94,324,673 (GRCm39) |
G1183W |
probably damaging |
Het |
| Capsl |
A |
T |
15: 9,461,828 (GRCm39) |
M75L |
probably benign |
Het |
| Ccdc122 |
T |
G |
14: 77,349,047 (GRCm39) |
|
probably benign |
Het |
| Ccdc57 |
T |
G |
11: 120,772,683 (GRCm39) |
R645S |
possibly damaging |
Het |
| Cdh8 |
T |
A |
8: 99,751,558 (GRCm39) |
R720* |
probably null |
Het |
| Cenpx |
T |
G |
11: 120,602,610 (GRCm39) |
|
probably benign |
Het |
| Clic3 |
T |
C |
2: 25,348,194 (GRCm39) |
S114P |
probably damaging |
Het |
| Cracdl |
A |
T |
1: 37,664,046 (GRCm39) |
D617E |
probably benign |
Het |
| Crtac1 |
A |
T |
19: 42,312,240 (GRCm39) |
W158R |
possibly damaging |
Het |
| Dennd2b |
C |
T |
7: 109,156,240 (GRCm39) |
G170D |
probably damaging |
Het |
| Dhrs11 |
T |
A |
11: 84,719,626 (GRCm39) |
Q33L |
probably benign |
Het |
| Dnah8 |
G |
A |
17: 30,967,542 (GRCm39) |
D2585N |
probably benign |
Het |
| Dpp9 |
G |
T |
17: 56,498,016 (GRCm39) |
Q647K |
probably damaging |
Het |
| Egf |
C |
T |
3: 129,510,327 (GRCm39) |
G64D |
probably damaging |
Het |
| Eif2b4 |
C |
T |
5: 31,346,864 (GRCm39) |
|
probably benign |
Het |
| Epas1 |
A |
G |
17: 87,113,267 (GRCm39) |
N151S |
probably benign |
Het |
| Fastkd1 |
A |
T |
2: 69,521,651 (GRCm39) |
I707K |
probably benign |
Het |
| Fbln2 |
A |
G |
6: 91,246,168 (GRCm39) |
T1005A |
probably benign |
Het |
| Fgfrl1 |
T |
A |
5: 108,851,363 (GRCm39) |
Y93* |
probably null |
Het |
| Fktn |
A |
G |
4: 53,744,637 (GRCm39) |
T306A |
probably benign |
Het |
| Gabbr2 |
T |
G |
4: 46,991,139 (GRCm39) |
Y96S |
possibly damaging |
Het |
| Gm16332 |
A |
T |
1: 139,819,396 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5145 |
G |
T |
17: 20,790,810 (GRCm39) |
V63F |
probably damaging |
Het |
| Gm9970 |
G |
T |
5: 31,398,429 (GRCm39) |
|
probably benign |
Het |
| Gpr158 |
A |
G |
2: 21,787,993 (GRCm39) |
T545A |
probably damaging |
Het |
| Heatr1 |
G |
A |
13: 12,426,929 (GRCm39) |
E685K |
probably benign |
Het |
| Herc6 |
A |
T |
6: 57,581,151 (GRCm39) |
I284F |
probably damaging |
Het |
| Hook1 |
C |
G |
4: 95,890,794 (GRCm39) |
A301G |
possibly damaging |
Het |
| Hpcal4 |
T |
A |
4: 123,084,491 (GRCm39) |
M140K |
possibly damaging |
Het |
| Il11ra1 |
T |
C |
4: 41,766,096 (GRCm39) |
|
probably benign |
Het |
| Ildr1 |
A |
T |
16: 36,542,917 (GRCm39) |
H439L |
possibly damaging |
Het |
| Itga11 |
A |
G |
9: 62,684,009 (GRCm39) |
|
probably null |
Het |
| Jag2 |
A |
T |
12: 112,880,252 (GRCm39) |
D337E |
probably benign |
Het |
| Krt82 |
C |
T |
15: 101,458,923 (GRCm39) |
R39Q |
probably benign |
Het |
| L3mbtl4 |
T |
A |
17: 68,666,475 (GRCm39) |
M1K |
probably null |
Het |
| Lrrc32 |
T |
G |
7: 98,148,224 (GRCm39) |
F335V |
probably damaging |
Het |
| Lurap1l |
T |
A |
4: 80,829,650 (GRCm39) |
V20E |
probably damaging |
Het |
| Lyar |
T |
A |
5: 38,385,230 (GRCm39) |
V90D |
possibly damaging |
Het |
| Man2c1 |
C |
T |
9: 57,048,469 (GRCm39) |
R778* |
probably null |
Het |
| Mapk6 |
A |
G |
9: 75,295,714 (GRCm39) |
F595L |
probably benign |
Het |
| Mccc1 |
A |
G |
3: 36,039,150 (GRCm39) |
I281T |
probably damaging |
Het |
| Mep1b |
T |
C |
18: 21,226,311 (GRCm39) |
V391A |
probably damaging |
Het |
| Mier1 |
G |
A |
4: 102,988,195 (GRCm39) |
D40N |
probably damaging |
Het |
| Mkx |
T |
C |
18: 7,002,432 (GRCm39) |
H38R |
probably benign |
Het |
| Mroh4 |
A |
G |
15: 74,498,028 (GRCm39) |
L184P |
probably damaging |
Het |
| Muc2 |
C |
A |
7: 141,307,877 (GRCm39) |
N834K |
probably benign |
Het |
| Mycl |
A |
G |
4: 122,894,049 (GRCm39) |
D283G |
probably damaging |
Het |
| Myh6 |
T |
C |
14: 55,190,750 (GRCm39) |
N975S |
probably damaging |
Het |
| Myl12a |
A |
G |
17: 71,303,297 (GRCm39) |
|
probably benign |
Het |
| Mysm1 |
T |
C |
4: 94,853,910 (GRCm39) |
T230A |
probably benign |
Het |
| Naca |
A |
G |
10: 127,883,672 (GRCm39) |
K2099R |
probably null |
Het |
| Nbeal1 |
T |
G |
1: 60,261,352 (GRCm39) |
|
probably null |
Het |
| Nedd1 |
A |
G |
10: 92,534,772 (GRCm39) |
V246A |
probably benign |
Het |
| Nid2 |
A |
G |
14: 19,839,829 (GRCm39) |
D806G |
probably benign |
Het |
| Ninl |
G |
A |
2: 150,801,801 (GRCm39) |
R156* |
probably null |
Het |
| Obscn |
T |
A |
11: 58,960,685 (GRCm39) |
I3418F |
probably damaging |
Het |
| Or8g37 |
T |
A |
9: 39,731,193 (GRCm39) |
V86E |
probably benign |
Het |
| Pappa2 |
T |
C |
1: 158,684,949 (GRCm39) |
N730S |
probably damaging |
Het |
| Pcm1 |
G |
A |
8: 41,746,715 (GRCm39) |
D1305N |
probably damaging |
Het |
| Pcsk4 |
A |
T |
10: 80,158,938 (GRCm39) |
I485N |
probably damaging |
Het |
| Phldb2 |
T |
C |
16: 45,646,237 (GRCm39) |
R111G |
probably damaging |
Het |
| Prdm10 |
T |
C |
9: 31,252,569 (GRCm39) |
F385S |
probably damaging |
Het |
| Prkcsh |
C |
T |
9: 21,923,034 (GRCm39) |
P351L |
probably damaging |
Het |
| Prrc2a |
G |
A |
17: 35,369,018 (GRCm39) |
P2006L |
probably damaging |
Het |
| Rad51c |
T |
C |
11: 87,286,204 (GRCm39) |
D251G |
probably damaging |
Het |
| Radil |
A |
G |
5: 142,470,918 (GRCm39) |
F1088L |
probably benign |
Het |
| Rere |
C |
A |
4: 150,699,624 (GRCm39) |
|
probably benign |
Het |
| Rnf167 |
T |
A |
11: 70,540,961 (GRCm39) |
C196S |
probably benign |
Het |
| Robo2 |
T |
A |
16: 74,149,633 (GRCm39) |
Y65F |
probably damaging |
Het |
| Scarf2 |
G |
A |
16: 17,621,371 (GRCm39) |
C319Y |
probably damaging |
Het |
| Sec24c |
A |
G |
14: 20,743,780 (GRCm39) |
D995G |
probably damaging |
Het |
| Selenbp1 |
T |
C |
3: 94,851,211 (GRCm39) |
L369S |
probably benign |
Het |
| Sgpl1 |
A |
T |
10: 60,959,123 (GRCm39) |
I53K |
possibly damaging |
Het |
| Sh3bp5 |
C |
A |
14: 31,099,452 (GRCm39) |
R265L |
probably benign |
Het |
| Slc1a6 |
A |
T |
10: 78,635,952 (GRCm39) |
Y339F |
probably damaging |
Het |
| Smchd1 |
G |
T |
17: 71,667,048 (GRCm39) |
Y1781* |
probably null |
Het |
| Smg1 |
T |
C |
7: 117,779,697 (GRCm39) |
S1233G |
probably benign |
Het |
| Snap91 |
A |
T |
9: 86,665,507 (GRCm39) |
|
probably benign |
Het |
| Snx29 |
T |
A |
16: 11,238,600 (GRCm39) |
L112Q |
probably damaging |
Het |
| Sptbn5 |
T |
C |
2: 119,889,622 (GRCm39) |
|
probably benign |
Het |
| Srl |
A |
T |
16: 4,310,222 (GRCm39) |
H502Q |
possibly damaging |
Het |
| St8sia3 |
A |
G |
18: 64,404,820 (GRCm39) |
M366V |
probably benign |
Het |
| Stk19 |
A |
T |
17: 35,041,485 (GRCm39) |
|
probably benign |
Het |
| Syngap1 |
G |
A |
17: 27,180,423 (GRCm39) |
A611T |
probably benign |
Het |
| Tas2r113 |
A |
G |
6: 132,870,670 (GRCm39) |
T233A |
possibly damaging |
Het |
| Tbcc |
G |
A |
17: 47,202,145 (GRCm39) |
W177* |
probably null |
Het |
| Tcstv3 |
T |
A |
13: 120,779,618 (GRCm39) |
|
probably null |
Het |
| Trav13-5 |
T |
A |
14: 54,033,408 (GRCm39) |
C106S |
probably damaging |
Het |
| Trmt61a |
G |
A |
12: 111,645,147 (GRCm39) |
V28M |
possibly damaging |
Het |
| Ubap2l |
G |
A |
3: 89,928,210 (GRCm39) |
T553M |
probably damaging |
Het |
| Ush2a |
T |
C |
1: 188,475,742 (GRCm39) |
L2893P |
probably damaging |
Het |
| Usp24 |
G |
A |
4: 106,217,359 (GRCm39) |
V421M |
possibly damaging |
Het |
| Vmn1r43 |
T |
C |
6: 89,846,892 (GRCm39) |
E198G |
probably benign |
Het |
| Vps13d |
A |
C |
4: 144,904,626 (GRCm39) |
S130A |
probably damaging |
Het |
| Zfp426 |
T |
A |
9: 20,382,310 (GRCm39) |
I211F |
probably benign |
Het |
| Znfx1 |
T |
C |
2: 166,880,489 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,550,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,575,986 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,589,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,601,346 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,554,649 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,574,448 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,557,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,566,474 (GRCm39) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,569,583 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,585,044 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,577,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,585,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,588,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,593,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,580,150 (GRCm39) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,574,310 (GRCm39) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,573,095 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,576,026 (GRCm39) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,570,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,607,185 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,566,335 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,573,206 (GRCm39) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,593,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,571,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1521:Urb1
|
UTSW |
16 |
90,550,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,574,328 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,557,340 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,570,936 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,569,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,584,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1672:Urb1
|
UTSW |
16 |
90,584,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Urb1
|
UTSW |
16 |
90,563,928 (GRCm39) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,558,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,559,232 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,571,686 (GRCm39) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,580,264 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,566,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,584,974 (GRCm39) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,571,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,566,282 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,585,034 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,584,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,573,159 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,573,017 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4672:Urb1
|
UTSW |
16 |
90,569,522 (GRCm39) |
missense |
probably benign |
|
|
R4681:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,550,406 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,566,443 (GRCm39) |
nonsense |
probably null |
|
|
R4809:Urb1
|
UTSW |
16 |
90,556,730 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,592,302 (GRCm39) |
nonsense |
probably null |
|
|
R4916:Urb1
|
UTSW |
16 |
90,580,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Urb1
|
UTSW |
16 |
90,602,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,553,059 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,548,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,548,983 (GRCm39) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,580,162 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,589,636 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5436:Urb1
|
UTSW |
16 |
90,589,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5767:Urb1
|
UTSW |
16 |
90,573,051 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,569,652 (GRCm39) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,559,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,585,985 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,600,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,575,982 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,550,807 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,559,318 (GRCm39) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,584,302 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,607,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,575,971 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,578,994 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,588,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Urb1
|
UTSW |
16 |
90,549,003 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7339:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,571,656 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,584,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,558,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,589,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,594,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,583,006 (GRCm39) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,576,040 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,588,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,571,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,600,311 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,607,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,571,005 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,550,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,566,290 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,589,638 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,569,463 (GRCm39) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,583,096 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,571,750 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,550,771 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATTTGGCCATTTCCAGAAGC -3'
(R):5'- CTTGTGGCTAATGGTCCCAG -3'
Sequencing Primer
(F):5'- TGGCCATTTCCAGAAGCTAGACTG -3'
(R):5'- GACCTCAAAAGTCTAGGACCATTG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation