Mutagenetix > Incidental Mutation

Incidental Mutation 'R4812:Apbb1'

369549

Institutional Source

Beutler Lab

Gene Symbol

Apbb1

Ensembl Gene

ENSMUSG00000037032

Gene Name

amyloid beta precursor protein binding family B member 1

Synonyms

Fe65, Rir

MMRRC Submission

042431-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4812 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

105207690-105230860 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 105223232 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 126 (N126K)

Ref Sequence

ENSEMBL: ENSMUSP00000140822 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000081165] [ENSMUST00000186868] [ENSMUST00000187051] [ENSMUST00000187683] [ENSMUST00000188440] [ENSMUST00000188726] [ENSMUST00000189072] [ENSMUST00000189378] [ENSMUST00000191011] [ENSMUST00000191601] [ENSMUST00000210079] [ENSMUST00000189265] [ENSMUST00000190369]

AlphaFold

Q9QXJ1

Predicted Effect

possibly damaging
Transcript: ENSMUST00000081165
AA Change: N126K

PolyPhen 2 Score 0.917 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000079932
Gene: ENSMUSG00000037032
AA Change: N126K

Domain	Start	End	E-Value	Type
low complexity region	146	184	N/A	INTRINSIC
WW	254	285	6.23e-5	SMART
low complexity region	287	299	N/A	INTRINSIC
PTB	365	512	4.16e-38	SMART
PTB	538	667	1.76e-36	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000186868

SMART Domains

Protein: ENSMUSP00000140052
Gene: ENSMUSG00000037032

Domain	Start	End	E-Value	Type
Pfam:WW	1	24	1.1e-5	PFAM
low complexity region	28	40	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000187051

SMART Domains

Protein: ENSMUSP00000139755
Gene: ENSMUSG00000037032

Domain	Start	End	E-Value	Type
Pfam:WW	1	24	1.4e-5	PFAM
low complexity region	28	40	N/A	INTRINSIC
SCOP:d1shca_	74	120	9e-7	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000187683

SMART Domains

Protein: ENSMUSP00000139426
Gene: ENSMUSG00000037032

Domain	Start	End	E-Value	Type
Pfam:WW	1	24	2.1e-5	PFAM
low complexity region	28	40	N/A	INTRINSIC
Pfam:PID	111	158	5.9e-6	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000188440

SMART Domains

Protein: ENSMUSP00000140715
Gene: ENSMUSG00000037032

Domain	Start	End	E-Value	Type
Pfam:WW	1	24	3.4e-5	PFAM
low complexity region	28	40	N/A	INTRINSIC
PTB	106	223	1.4e-14	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000188726
AA Change: N126K

PolyPhen 2 Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)

Predicted Effect

probably benign
Transcript: ENSMUST00000189072

SMART Domains

Protein: ENSMUSP00000139575
Gene: ENSMUSG00000037032

Domain	Start	End	E-Value	Type
Pfam:WW	1	24	8.1e-5	PFAM
low complexity region	28	40	N/A	INTRINSIC
PTB	106	253	1.8e-40	SMART
PTB	279	408	9.5e-39	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000189378
AA Change: N126K

PolyPhen 2 Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000140979
Gene: ENSMUSG00000037032
AA Change: N126K

Domain	Start	End	E-Value	Type
low complexity region	146	184	N/A	INTRINSIC
WW	254	285	6.23e-5	SMART
low complexity region	287	299	N/A	INTRINSIC
PTB	365	510	6.86e-39	SMART
PTB	536	665	1.76e-36	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000191011
AA Change: N126K

PolyPhen 2 Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000140973
Gene: ENSMUSG00000037032
AA Change: N126K

Domain	Start	End	E-Value	Type
low complexity region	146	184	N/A	INTRINSIC
WW	254	285	6.23e-5	SMART
low complexity region	287	299	N/A	INTRINSIC
PTB	365	510	6.86e-39	SMART
PTB	536	665	1.76e-36	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000191601
AA Change: N126K

PolyPhen 2 Score 0.710 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000140116
Gene: ENSMUSG00000037032
AA Change: N126K

Domain	Start	End	E-Value	Type
low complexity region	146	184	N/A	INTRINSIC
WW	254	285	3.7e-7	SMART
low complexity region	287	299	N/A	INTRINSIC
PTB	365	512	1.8e-40	SMART
PTB	538	667	9.5e-39	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000210079

Predicted Effect

probably benign
Transcript: ENSMUST00000189265

SMART Domains

Protein: ENSMUSP00000140137
Gene: ENSMUSG00000037032

Domain	Start	End	E-Value	Type
Pfam:PID	1	34	2.3e-6	PFAM
PTB	63	192	9.5e-39	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000190369

SMART Domains

Protein: ENSMUSP00000140486
Gene: ENSMUSG00000037032

Domain	Start	End	E-Value	Type
Pfam:WW	1	24	8.1e-5	PFAM
low complexity region	28	40	N/A	INTRINSIC
PTB	106	253	1.8e-40	SMART
PTB	279	408	9.5e-39	SMART

Meta Mutation Damage Score

0.6467

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.2%

Validation Efficiency

93% (124/133)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
PHENOTYPE: Homozygotes for a null allele are hypersensitive to ionizing radiation while mouse embryonic fibroblasts are hypersensitive to DNA damaging agents. Homozygotes for a second null allele display impaired performance in learning and memory tasks, with a striking deficit in reversal spatial learning. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 128 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700017G19Rik	C	T	3: 40,575,633 (GRCm39)		noncoding transcript	Het
Abca5	T	C	11: 110,192,647 (GRCm39)	D681G	probably damaging	Het
Actl11	T	C	9: 107,808,329 (GRCm39)	V884A	probably damaging	Het
Akr1c14	G	A	13: 4,129,165 (GRCm39)	V187M	probably damaging	Het
Bmt2	G	T	6: 13,677,799 (GRCm39)	R12S	unknown	Het
Btrc	G	A	19: 45,411,603 (GRCm39)	C9Y	possibly damaging	Het
C5ar1	A	C	7: 15,982,258 (GRCm39)		probably null	Het
C8a	C	T	4: 104,719,788 (GRCm39)		probably null	Het
Cabin1	A	G	10: 75,482,428 (GRCm39)	S2172P	possibly damaging	Het
Calcoco2	T	C	11: 95,998,276 (GRCm39)	D49G	probably damaging	Het
Camta1	C	T	4: 151,215,999 (GRCm39)	D974N	probably null	Het
Car6	T	C	4: 150,281,872 (GRCm39)	E47G	probably damaging	Het
Ccnd3	G	A	17: 47,908,505 (GRCm39)		probably null	Het
Celf5	A	T	10: 81,306,573 (GRCm39)	V30E	probably damaging	Het
Cfap251	G	A	5: 123,425,368 (GRCm39)	V776I	probably benign	Het
Cfap46	T	A	7: 139,215,916 (GRCm39)	D1513V	probably damaging	Het
Cinp	T	C	12: 110,846,174 (GRCm39)	Y84C	probably damaging	Het
Cnih1	A	G	14: 47,014,001 (GRCm39)	I154T	probably damaging	Het
Col15a1	C	T	4: 47,262,479 (GRCm39)	P511L	possibly damaging	Het
Col4a4	C	T	1: 82,439,874 (GRCm39)	V1364M	unknown	Het
Cplane1	T	G	15: 8,230,607 (GRCm39)		probably null	Het
Crtam	A	G	9: 40,895,621 (GRCm39)	L38P	probably damaging	Het
Ctnna1	T	A	18: 35,372,530 (GRCm39)	V495D	probably damaging	Het
Cubn	T	C	2: 13,463,887 (GRCm39)	Y606C	probably damaging	Het
Cyp4f16	C	T	17: 32,765,652 (GRCm39)	A345V	probably null	Het
Dctn1	A	T	6: 83,166,919 (GRCm39)	M160L	probably benign	Het
Dip2c	T	A	13: 9,687,166 (GRCm39)	C366*	probably null	Het
Dnajc2	G	A	5: 21,968,484 (GRCm39)	S401L	probably benign	Het
Dnmt3l	A	G	10: 77,893,128 (GRCm39)	I302V	probably benign	Het
Dvl2	T	C	11: 69,902,119 (GRCm39)		probably benign	Het
Edn1	T	G	13: 42,457,116 (GRCm39)	S50A	probably benign	Het
Efhc1	A	T	1: 21,060,871 (GRCm39)	R636W	probably damaging	Het
Epg5	T	A	18: 78,022,399 (GRCm39)	H1047Q	probably benign	Het
Etv1	T	G	12: 38,911,287 (GRCm39)	V371G	probably damaging	Het
Fap	T	A	2: 62,349,365 (GRCm39)	I475F	probably damaging	Het
Fbxw15	T	C	9: 109,388,990 (GRCm39)	I140V	probably benign	Het
Fer	A	G	17: 64,241,292 (GRCm39)	T311A	probably benign	Het
Fh1	A	G	1: 175,429,025 (GRCm39)	W497R	probably damaging	Het
Flot2	T	A	11: 77,944,191 (GRCm39)	L45Q	probably damaging	Het
Flt1	C	A	5: 147,620,749 (GRCm39)	A132S	probably benign	Het
Fmnl1	T	C	11: 103,089,390 (GRCm39)		probably benign	Het
Garin5b	G	A	7: 4,762,071 (GRCm39)	T295M	probably damaging	Het
Ggta1	C	T	2: 35,292,735 (GRCm39)	V203I	probably benign	Het
Gm19345	C	T	7: 19,591,798 (GRCm39)	V204M	probably damaging	Het
Gm4204	T	A	1: 135,160,227 (GRCm39)		noncoding transcript	Het
Gm6124	C	G	7: 38,872,319 (GRCm39)		noncoding transcript	Het
Gprin3	T	A	6: 59,330,350 (GRCm39)	K652N	possibly damaging	Het
Gucy1b2	T	C	14: 62,653,346 (GRCm39)		probably null	Het
Hace1	C	A	10: 45,562,699 (GRCm39)	A738E	probably benign	Het
Hectd1	C	T	12: 51,874,134 (GRCm39)		probably null	Het
Hnrnpdl	T	C	5: 100,184,331 (GRCm39)		probably benign	Het
Hyou1	T	C	9: 44,298,418 (GRCm39)		probably benign	Het
Ifi44l	G	A	3: 151,465,336 (GRCm39)	A138V	probably benign	Het
Igkv16-104	A	T	6: 68,402,829 (GRCm39)	I41F	possibly damaging	Het
Ints7	T	A	1: 191,326,542 (GRCm39)	D171E	possibly damaging	Het
Irag2	G	A	6: 145,093,737 (GRCm39)	G120S	probably damaging	Het
Kmt2a	A	T	9: 44,742,651 (GRCm39)		probably benign	Het
Kmt2e	T	C	5: 23,707,585 (GRCm39)	V1716A	possibly damaging	Het
Krtap5-1	G	A	7: 141,850,628 (GRCm39)	S60F	unknown	Het
Lama4	G	A	10: 38,948,765 (GRCm39)	V843I	probably benign	Het
Laptm5	A	G	4: 130,640,749 (GRCm39)		probably null	Het
Lbhd1	G	A	19: 8,866,538 (GRCm39)	A193T	probably damaging	Het
Lce3f	C	T	3: 92,900,247 (GRCm39)	P23S	unknown	Het
Mecom	A	C	3: 30,194,517 (GRCm39)	M1R	probably null	Het
Mindy4	A	C	6: 55,256,088 (GRCm39)	T531P	possibly damaging	Het
Mrpl3	A	G	9: 104,951,023 (GRCm39)	N263S	probably damaging	Het
Myo18b	T	C	5: 112,957,584 (GRCm39)	K1460E	possibly damaging	Het
Myof	A	G	19: 37,905,007 (GRCm39)	Y852H	probably damaging	Het
Nefl	T	G	14: 68,321,734 (GRCm39)	V108G	probably damaging	Het
Nid1	T	A	13: 13,681,053 (GRCm39)	L1061*	probably null	Het
Nim1k	T	A	13: 120,173,920 (GRCm39)	M325L	probably benign	Het
Nlrp1c-ps	T	C	11: 71,143,131 (GRCm39)		noncoding transcript	Het
Npsr1	C	T	9: 24,201,252 (GRCm39)	T59I	probably damaging	Het
Nr2c1	A	G	10: 94,024,114 (GRCm39)	T440A	probably benign	Het
Nup160	C	T	2: 90,556,035 (GRCm39)	T1245I	probably damaging	Het
Nup88	T	A	11: 70,856,552 (GRCm39)	T194S	probably damaging	Het
Oas3	A	G	5: 120,899,212 (GRCm39)		probably benign	Het
Odad2	T	G	18: 7,288,634 (GRCm39)	T78P	possibly damaging	Het
Opn1sw	A	T	6: 29,378,038 (GRCm39)	M252K	probably damaging	Het
Oprm1	T	G	10: 6,782,698 (GRCm39)		probably benign	Het
Or10ag59	A	G	2: 87,406,087 (GRCm39)	I220V	probably benign	Het
Or2y1g	T	A	11: 49,171,284 (GRCm39)	I103K	possibly damaging	Het
Or4x13	T	A	2: 90,231,440 (GRCm39)	M145K	probably benign	Het
Pcdha2	T	A	18: 37,072,861 (GRCm39)	V164E	probably benign	Het
Pclo	A	G	5: 14,590,039 (GRCm39)	T780A	unknown	Het
Pcnx2	T	A	8: 126,592,678 (GRCm39)	Q762L	probably benign	Het
Pcyt2	A	T	11: 120,505,251 (GRCm39)		probably benign	Het
Pdpr	A	G	8: 111,843,349 (GRCm39)	N294D	probably benign	Het
Perm1	T	A	4: 156,303,193 (GRCm39)	V579E	possibly damaging	Het
Pgk2	T	A	17: 40,518,281 (GRCm39)	K382N	possibly damaging	Het
Plcb4	T	A	2: 135,849,801 (GRCm39)	L205Q	probably damaging	Het
Plekha3	C	T	2: 76,516,975 (GRCm39)	T109I	probably damaging	Het
Pnn	T	A	12: 59,118,404 (GRCm39)	V329E	possibly damaging	Het
Ptpn13	A	G	5: 103,671,481 (GRCm39)	I469M	probably benign	Het
Rapgef3	A	G	15: 97,651,684 (GRCm39)	V603A	probably benign	Het
Rbms1	C	T	2: 60,623,113 (GRCm39)	V75I	possibly damaging	Het
Rbp3	T	A	14: 33,676,731 (GRCm39)	D226E	probably damaging	Het
Robo2	A	T	16: 73,713,176 (GRCm39)	N1189K	probably benign	Het
Rragd	A	G	4: 33,018,766 (GRCm39)	T270A	probably benign	Het
Rxfp1	T	A	3: 79,557,889 (GRCm39)	T530S	probably benign	Het
Ryr3	T	C	2: 112,742,581 (GRCm39)	E479G	probably damaging	Het
Scd2	A	T	19: 44,289,841 (GRCm39)	I279F	probably damaging	Het
Sh3d19	A	T	3: 86,031,074 (GRCm39)	D746V	probably damaging	Het
Shroom4	A	G	X: 6,536,180 (GRCm39)	K1133E	probably benign	Het
Sirpb1c	A	G	3: 15,887,386 (GRCm39)	V151A	probably damaging	Het
Slc26a2	A	T	18: 61,335,093 (GRCm39)	I120N	probably damaging	Het
Slco1a1	A	G	6: 141,864,319 (GRCm39)	S494P	probably damaging	Het
Srebf2	A	T	15: 82,088,026 (GRCm39)	T1061S	probably damaging	Het
Sspo	T	C	6: 48,467,444 (GRCm39)	L4202P	probably benign	Het
Synj2	G	A	17: 6,060,939 (GRCm39)	G215E	probably damaging	Het
Tbc1d19	T	C	5: 53,967,148 (GRCm39)	V16A	probably damaging	Het
Tektl1	T	C	10: 78,585,050 (GRCm39)	H262R	probably benign	Het
Tiparp	T	C	3: 65,460,190 (GRCm39)	I495T	possibly damaging	Het
Tipin	A	G	9: 64,211,694 (GRCm39)	H260R	probably benign	Het
Tle1	A	G	4: 72,063,591 (GRCm39)	S221P	probably damaging	Het
Tmem94	T	A	11: 115,686,938 (GRCm39)	L1101*	probably null	Het
Trim43b	C	T	9: 88,973,533 (GRCm39)	D67N	probably benign	Het
Ubn2	T	A	6: 38,440,661 (GRCm39)	C178S	probably benign	Het
Vmn1r54	T	C	6: 90,246,307 (GRCm39)	F74L	probably benign	Het
Vmn2r24	A	G	6: 123,756,144 (GRCm39)	H72R	probably benign	Het
Wnk1	C	T	6: 119,929,732 (GRCm39)	V850I	probably benign	Het
Zan	T	G	5: 137,454,547 (GRCm39)	Y1419S	unknown	Het
Zbtb14	T	A	17: 69,694,577 (GRCm39)	Y92N	probably damaging	Het
Zfand5	A	G	19: 21,255,101 (GRCm39)	K116E	probably benign	Het
Zfhx3	A	G	8: 109,674,593 (GRCm39)	E1881G	possibly damaging	Het
Zfp280b	A	G	10: 75,874,924 (GRCm39)	K268E	probably benign	Het
Zfp541	A	G	7: 15,813,035 (GRCm39)	I563V	probably benign	Het
Zfy2	T	A	Y: 2,106,334 (GRCm39)	I767L	probably benign	Het

Other mutations in Apbb1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02171:Apbb1	APN	7	105,208,333 (GRCm39)	splice site	probably benign
athena	UTSW	7	105,215,902 (GRCm39)	missense	probably benign
R0092:Apbb1	UTSW	7	105,208,361 (GRCm39)	missense	probably damaging	1.00
R0348:Apbb1	UTSW	7	105,214,510 (GRCm39)	missense	probably damaging	0.98
R0633:Apbb1	UTSW	7	105,208,170 (GRCm39)	missense	probably damaging	1.00
R0946:Apbb1	UTSW	7	105,223,062 (GRCm39)	missense	probably benign	0.09
R1076:Apbb1	UTSW	7	105,223,062 (GRCm39)	missense	probably benign	0.09
R1332:Apbb1	UTSW	7	105,214,750 (GRCm39)	missense	possibly damaging	0.74
R1658:Apbb1	UTSW	7	105,223,291 (GRCm39)	missense	probably damaging	1.00
R1739:Apbb1	UTSW	7	105,223,434 (GRCm39)	missense	probably benign
R4230:Apbb1	UTSW	7	105,216,891 (GRCm39)	missense	probably damaging	1.00
R4296:Apbb1	UTSW	7	105,223,033 (GRCm39)	missense	probably benign	0.16
R4385:Apbb1	UTSW	7	105,216,483 (GRCm39)	missense	probably benign	0.00
R4571:Apbb1	UTSW	7	105,222,969 (GRCm39)	missense	probably damaging	1.00
R4647:Apbb1	UTSW	7	105,214,745 (GRCm39)	missense	probably benign	0.01
R5044:Apbb1	UTSW	7	105,214,889 (GRCm39)	intron	probably benign
R5109:Apbb1	UTSW	7	105,214,242 (GRCm39)	missense	probably damaging	1.00
R5479:Apbb1	UTSW	7	105,214,232 (GRCm39)	missense	probably damaging	0.97
R5611:Apbb1	UTSW	7	105,208,690 (GRCm39)	missense	probably damaging	1.00
R5677:Apbb1	UTSW	7	105,208,453 (GRCm39)	missense	probably damaging	1.00
R5785:Apbb1	UTSW	7	105,216,922 (GRCm39)	missense	probably damaging	1.00
R5850:Apbb1	UTSW	7	105,216,790 (GRCm39)	missense	probably damaging	1.00
R5896:Apbb1	UTSW	7	105,223,432 (GRCm39)	missense	probably damaging	1.00
R6151:Apbb1	UTSW	7	105,223,459 (GRCm39)	nonsense	probably null
R6186:Apbb1	UTSW	7	105,216,933 (GRCm39)	missense	probably damaging	1.00
R6229:Apbb1	UTSW	7	105,222,938 (GRCm39)	missense	probably damaging	0.98
R6229:Apbb1	UTSW	7	105,222,937 (GRCm39)	missense	probably damaging	0.98
R6288:Apbb1	UTSW	7	105,208,434 (GRCm39)	missense	probably damaging	1.00
R6295:Apbb1	UTSW	7	105,215,902 (GRCm39)	missense	probably benign
R6443:Apbb1	UTSW	7	105,222,970 (GRCm39)	missense	probably damaging	1.00
R6729:Apbb1	UTSW	7	105,214,588 (GRCm39)	missense	probably damaging	1.00
R7130:Apbb1	UTSW	7	105,214,538 (GRCm39)	missense	probably damaging	0.98
R7209:Apbb1	UTSW	7	105,215,292 (GRCm39)	missense	probably damaging	1.00
R7467:Apbb1	UTSW	7	105,215,339 (GRCm39)	missense	probably benign	0.04
R7489:Apbb1	UTSW	7	105,216,687 (GRCm39)	missense	probably benign	0.30
R7588:Apbb1	UTSW	7	105,223,173 (GRCm39)	missense	probably benign	0.29
R7754:Apbb1	UTSW	7	105,208,509 (GRCm39)	missense	probably damaging	0.97
R7768:Apbb1	UTSW	7	105,216,295 (GRCm39)	missense	probably benign
R7785:Apbb1	UTSW	7	105,216,630 (GRCm39)	missense	probably benign	0.00
R7804:Apbb1	UTSW	7	105,215,807 (GRCm39)	missense	probably damaging	1.00
R7809:Apbb1	UTSW	7	105,223,014 (GRCm39)	missense	probably benign	0.04
R7995:Apbb1	UTSW	7	105,214,852 (GRCm39)	missense	probably benign	0.09
R9206:Apbb1	UTSW	7	105,208,727 (GRCm39)	missense	probably damaging	0.97
R9208:Apbb1	UTSW	7	105,208,727 (GRCm39)	missense	probably damaging	0.97
R9225:Apbb1	UTSW	7	105,218,063 (GRCm39)	missense
Z1088:Apbb1	UTSW	7	105,208,343 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTCTCCAGAGGCTCAGGTAG -3'
(R):5'- CTTCGAAGTGCTATGGGAGAGG -3'

Sequencing Primer
(F):5'- GCCCTGGAGGAGAAGACAAGTC -3'
(R):5'- CCTGCCAATGCCAAGTGGTTAAAG -3'

Posted On

2016-02-04