Incidental Mutation 'R4838:Sgsm1'
| ID |
371514 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sgsm1
|
| Ensembl Gene |
ENSMUSG00000042216 |
| Gene Name |
small G protein signaling modulator 1 |
| Synonyms |
Rutbc2, D5Bwg1524e, 2410098H20Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4838 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
113391086-113458652 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 113430492 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Tyrosine
at position 298
(N298Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000046544
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048112]
[ENSMUST00000057209]
[ENSMUST00000112324]
[ENSMUST00000112325]
[ENSMUST00000154248]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000048112
AA Change: N298Y
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000046544
Gene: ENSMUSG00000042216
AA Change: N298Y
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
469 |
N/A |
INTRINSIC |
|
TBC
|
559 |
1053 |
2.88e-29 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000057209
|
| SMART Domains |
Protein: ENSMUSP00000084106
Gene: ENSMUSG00000042216
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
167 |
182 |
N/A |
INTRINSIC |
|
TBC
|
272 |
766 |
2.88e-29 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112324
|
| SMART Domains |
Protein: ENSMUSP00000107943
Gene: ENSMUSG00000042216
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
167 |
182 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112325
AA Change: N298Y
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000107944
Gene: ENSMUSG00000042216
AA Change: N298Y
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
469 |
N/A |
INTRINSIC |
|
SCOP:d1fkma1
|
539 |
615 |
1e-6 |
SMART |
|
Blast:TBC
|
559 |
675 |
1e-71 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000138266
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140981
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145708
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000154248
AA Change: N298Y
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000114932
Gene: ENSMUSG00000042216
AA Change: N298Y
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
524 |
N/A |
INTRINSIC |
|
SCOP:d1fkma1
|
594 |
670 |
9e-7 |
SMART |
|
Blast:TBC
|
614 |
706 |
3e-55 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156340
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147856
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
T |
C |
7: 119,944,523 (GRCm39) |
V386A |
probably benign |
Het |
| Adk |
G |
A |
14: 21,419,154 (GRCm39) |
A247T |
probably damaging |
Het |
| Ankrd27 |
T |
A |
7: 35,291,231 (GRCm39) |
L9Q |
possibly damaging |
Het |
| Atad2 |
A |
G |
15: 57,966,679 (GRCm39) |
L638P |
probably damaging |
Het |
| Atf7ip |
T |
A |
6: 136,573,489 (GRCm39) |
D1009E |
probably benign |
Het |
| Bend7 |
A |
T |
2: 4,749,133 (GRCm39) |
K83N |
probably damaging |
Het |
| Bicc1 |
C |
T |
10: 70,781,146 (GRCm39) |
D562N |
possibly damaging |
Het |
| Calcrl |
T |
A |
2: 84,181,549 (GRCm39) |
N200Y |
probably damaging |
Het |
| Ccdc125 |
C |
A |
13: 100,814,453 (GRCm39) |
A11E |
possibly damaging |
Het |
| Cd5l |
A |
G |
3: 87,273,258 (GRCm39) |
T76A |
probably benign |
Het |
| Cdhr5 |
A |
T |
7: 140,853,644 (GRCm39) |
I2N |
probably damaging |
Het |
| Cdk10 |
C |
T |
8: 123,957,353 (GRCm39) |
A230V |
probably damaging |
Het |
| Cep128 |
T |
C |
12: 90,966,319 (GRCm39) |
|
probably benign |
Het |
| Cep131 |
T |
C |
11: 119,966,982 (GRCm39) |
N186D |
probably damaging |
Het |
| Cfhr4 |
T |
A |
1: 139,661,181 (GRCm39) |
D556V |
probably damaging |
Het |
| Cog7 |
G |
T |
7: 121,570,604 (GRCm39) |
P168Q |
probably damaging |
Het |
| Col28a1 |
T |
A |
6: 8,014,559 (GRCm39) |
M949L |
probably benign |
Het |
| Coq8b |
T |
A |
7: 26,950,016 (GRCm39) |
M365K |
probably damaging |
Het |
| Cpa1 |
A |
G |
6: 30,639,515 (GRCm39) |
E18G |
possibly damaging |
Het |
| Csmd2 |
A |
G |
4: 128,411,542 (GRCm39) |
H2520R |
probably benign |
Het |
| Cyp2c69 |
T |
C |
19: 39,866,038 (GRCm39) |
N185S |
probably benign |
Het |
| Dpm1 |
G |
A |
2: 168,052,456 (GRCm39) |
T260I |
probably damaging |
Het |
| Dtx3 |
A |
T |
10: 127,027,176 (GRCm39) |
|
probably null |
Het |
| Eepd1 |
T |
C |
9: 25,500,756 (GRCm39) |
V401A |
possibly damaging |
Het |
| Ehhadh |
A |
G |
16: 21,581,952 (GRCm39) |
S347P |
possibly damaging |
Het |
| Elp3 |
A |
G |
14: 65,785,313 (GRCm39) |
|
probably null |
Het |
| Enam |
C |
T |
5: 88,640,967 (GRCm39) |
Q210* |
probably null |
Het |
| Epha1 |
C |
T |
6: 42,340,750 (GRCm39) |
R607H |
probably benign |
Het |
| Erich6 |
A |
G |
3: 58,544,251 (GRCm39) |
I112T |
probably benign |
Het |
| F830045P16Rik |
A |
G |
2: 129,302,470 (GRCm39) |
V374A |
possibly damaging |
Het |
| Fam171a2 |
C |
A |
11: 102,329,511 (GRCm39) |
R416L |
possibly damaging |
Het |
| Fbn1 |
T |
C |
2: 125,214,319 (GRCm39) |
N764S |
probably benign |
Het |
| Fip1l1 |
C |
T |
5: 74,752,600 (GRCm39) |
T469I |
probably damaging |
Het |
| Flad1 |
G |
A |
3: 89,313,217 (GRCm39) |
R342C |
probably damaging |
Het |
| Fzd3 |
A |
G |
14: 65,477,269 (GRCm39) |
V95A |
probably benign |
Het |
| Garem1 |
T |
C |
18: 21,280,950 (GRCm39) |
T469A |
probably benign |
Het |
| Gm17093 |
A |
G |
14: 44,755,805 (GRCm39) |
Y24C |
unknown |
Het |
| Grap2 |
T |
C |
15: 80,522,762 (GRCm39) |
V96A |
possibly damaging |
Het |
| Greb1 |
A |
T |
12: 16,734,361 (GRCm39) |
|
probably null |
Het |
| Grid2ip |
A |
T |
5: 143,374,530 (GRCm39) |
K913* |
probably null |
Het |
| Gzmk |
T |
C |
13: 113,309,555 (GRCm39) |
D126G |
probably damaging |
Het |
| Hibch |
A |
G |
1: 52,924,337 (GRCm39) |
I171V |
possibly damaging |
Het |
| Hipk2 |
G |
T |
6: 38,795,339 (GRCm39) |
T310K |
possibly damaging |
Het |
| Hk3 |
T |
C |
13: 55,154,231 (GRCm39) |
Y815C |
probably damaging |
Het |
| Hps5 |
A |
T |
7: 46,437,778 (GRCm39) |
V99E |
probably damaging |
Het |
| Hspg2 |
A |
G |
4: 137,268,977 (GRCm39) |
H2203R |
possibly damaging |
Het |
| Il12rb2 |
A |
G |
6: 67,286,121 (GRCm39) |
V108A |
probably damaging |
Het |
| Il6st |
C |
T |
13: 112,627,044 (GRCm39) |
R279* |
probably null |
Het |
| Kdm2a |
A |
C |
19: 4,375,054 (GRCm39) |
S692R |
probably benign |
Het |
| Kif13a |
T |
C |
13: 46,980,224 (GRCm39) |
K176R |
probably damaging |
Het |
| Kif5b |
T |
C |
18: 6,216,869 (GRCm39) |
K485E |
probably damaging |
Het |
| Ktn1 |
C |
T |
14: 47,963,413 (GRCm39) |
R1111* |
probably null |
Het |
| Lrrc23 |
A |
T |
6: 124,755,152 (GRCm39) |
N128K |
probably benign |
Het |
| Mad1l1 |
G |
A |
5: 140,286,017 (GRCm39) |
Q293* |
probably null |
Het |
| Man1b1 |
A |
T |
2: 25,235,487 (GRCm39) |
I338F |
possibly damaging |
Het |
| Marchf1 |
G |
T |
8: 66,921,015 (GRCm39) |
V225L |
probably damaging |
Het |
| Matcap2 |
A |
T |
9: 22,335,673 (GRCm39) |
D97V |
probably damaging |
Het |
| Mrpl3 |
A |
G |
9: 104,934,231 (GRCm39) |
D118G |
probably damaging |
Het |
| Nomo1 |
A |
T |
7: 45,733,139 (GRCm39) |
Q1209L |
unknown |
Het |
| Nrcam |
A |
G |
12: 44,620,802 (GRCm39) |
E949G |
probably damaging |
Het |
| Olfm5 |
T |
G |
7: 103,803,572 (GRCm39) |
N297T |
probably damaging |
Het |
| Or51h7 |
T |
A |
7: 102,591,453 (GRCm39) |
L110F |
probably damaging |
Het |
| Pcdh7 |
A |
T |
5: 57,878,146 (GRCm39) |
N567I |
probably damaging |
Het |
| Pkn1 |
A |
G |
8: 84,404,595 (GRCm39) |
L495P |
probably damaging |
Het |
| Pkp1 |
T |
C |
1: 135,810,326 (GRCm39) |
S415G |
probably damaging |
Het |
| Pou2f1 |
T |
A |
1: 165,744,492 (GRCm39) |
Q53L |
probably null |
Het |
| Pramel26 |
G |
A |
4: 143,537,375 (GRCm39) |
Q319* |
probably null |
Het |
| Prkce |
A |
G |
17: 86,937,511 (GRCm39) |
K648R |
probably benign |
Het |
| Ptprh |
G |
A |
7: 4,576,429 (GRCm39) |
T277I |
possibly damaging |
Het |
| Rpl31 |
C |
T |
1: 39,410,048 (GRCm39) |
R83C |
probably benign |
Het |
| Rpusd3 |
G |
A |
6: 113,393,837 (GRCm39) |
Q194* |
probably null |
Het |
| She |
G |
A |
3: 89,758,946 (GRCm39) |
G355D |
probably benign |
Het |
| Shld2 |
A |
G |
14: 33,990,582 (GRCm39) |
V108A |
probably benign |
Het |
| Snx11 |
C |
T |
11: 96,665,284 (GRCm39) |
E9K |
possibly damaging |
Het |
| Soat1 |
C |
A |
1: 156,260,507 (GRCm39) |
A444S |
probably benign |
Het |
| Sox6 |
T |
C |
7: 115,085,897 (GRCm39) |
Y690C |
probably damaging |
Het |
| Spata13 |
T |
A |
14: 60,970,628 (GRCm39) |
F10I |
probably benign |
Het |
| St18 |
C |
A |
1: 6,873,129 (GRCm39) |
T288K |
probably benign |
Het |
| Tifa |
C |
T |
3: 127,590,235 (GRCm39) |
S2F |
probably damaging |
Het |
| Tmem232 |
A |
T |
17: 65,737,883 (GRCm39) |
S392R |
probably benign |
Het |
| Tmtc3 |
T |
C |
10: 100,302,082 (GRCm39) |
N289S |
probably damaging |
Het |
| Tpo |
A |
G |
12: 30,142,633 (GRCm39) |
F697S |
probably damaging |
Het |
| Trp53 |
A |
G |
11: 69,478,456 (GRCm39) |
T122A |
probably damaging |
Het |
| Trps1 |
A |
C |
15: 50,690,712 (GRCm39) |
I10S |
probably benign |
Het |
| Tubgcp5 |
C |
T |
7: 55,443,933 (GRCm39) |
|
probably benign |
Het |
| Unc13c |
T |
G |
9: 73,839,354 (GRCm39) |
Y499S |
possibly damaging |
Het |
| Unc45a |
C |
A |
7: 79,982,783 (GRCm39) |
D381Y |
probably damaging |
Het |
| Upf1 |
G |
C |
8: 70,792,018 (GRCm39) |
H402Q |
probably benign |
Het |
| Uroc1 |
A |
T |
6: 90,326,174 (GRCm39) |
I510F |
possibly damaging |
Het |
| Usp15 |
A |
G |
10: 122,963,662 (GRCm39) |
F589L |
probably damaging |
Het |
| Vmn2r76 |
T |
C |
7: 85,874,733 (GRCm39) |
Y748C |
probably damaging |
Het |
| Wwp1 |
T |
C |
4: 19,662,143 (GRCm39) |
N151D |
probably benign |
Het |
| Zbtb40 |
A |
T |
4: 136,728,527 (GRCm39) |
S439T |
probably benign |
Het |
| Zbtb6 |
A |
T |
2: 37,318,728 (GRCm39) |
L400* |
probably null |
Het |
| Zfp125 |
C |
T |
12: 20,949,961 (GRCm39) |
|
noncoding transcript |
Het |
| Zmynd8 |
A |
C |
2: 165,681,954 (GRCm39) |
Y183* |
probably null |
Het |
| Zpld2 |
A |
G |
4: 133,920,410 (GRCm39) |
V585A |
probably benign |
Het |
|
| Other mutations in Sgsm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00230:Sgsm1
|
APN |
5 |
113,392,930 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Sgsm1
|
APN |
5 |
113,424,008 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01377:Sgsm1
|
APN |
5 |
113,424,048 (GRCm39) |
splice site |
probably benign |
|
|
IGL01602:Sgsm1
|
APN |
5 |
113,433,531 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01605:Sgsm1
|
APN |
5 |
113,433,531 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01669:Sgsm1
|
APN |
5 |
113,411,356 (GRCm39) |
missense |
probably benign |
|
|
IGL01920:Sgsm1
|
APN |
5 |
113,421,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01951:Sgsm1
|
APN |
5 |
113,434,633 (GRCm39) |
splice site |
probably benign |
|
|
IGL02387:Sgsm1
|
APN |
5 |
113,400,929 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02690:Sgsm1
|
APN |
5 |
113,434,633 (GRCm39) |
splice site |
probably benign |
|
|
IGL03177:Sgsm1
|
APN |
5 |
113,398,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03186:Sgsm1
|
APN |
5 |
113,432,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03398:Sgsm1
|
APN |
5 |
113,403,182 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
caliente
|
UTSW |
5 |
113,428,328 (GRCm39) |
intron |
probably benign |
|
|
Chili
|
UTSW |
5 |
113,405,989 (GRCm39) |
intron |
probably benign |
|
|
pimiento
|
UTSW |
5 |
113,411,123 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0048:Sgsm1
|
UTSW |
5 |
113,416,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Sgsm1
|
UTSW |
5 |
113,432,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Sgsm1
|
UTSW |
5 |
113,432,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0082:Sgsm1
|
UTSW |
5 |
113,436,702 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0085:Sgsm1
|
UTSW |
5 |
113,427,136 (GRCm39) |
splice site |
probably benign |
|
|
R0099:Sgsm1
|
UTSW |
5 |
113,422,226 (GRCm39) |
splice site |
probably benign |
|
|
R0269:Sgsm1
|
UTSW |
5 |
113,434,795 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0310:Sgsm1
|
UTSW |
5 |
113,411,571 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0325:Sgsm1
|
UTSW |
5 |
113,436,701 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0420:Sgsm1
|
UTSW |
5 |
113,411,625 (GRCm39) |
missense |
probably benign |
0.16 |
|
R0594:Sgsm1
|
UTSW |
5 |
113,458,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0599:Sgsm1
|
UTSW |
5 |
113,392,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0631:Sgsm1
|
UTSW |
5 |
113,432,989 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Sgsm1
|
UTSW |
5 |
113,427,050 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0833:Sgsm1
|
UTSW |
5 |
113,427,050 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0919:Sgsm1
|
UTSW |
5 |
113,406,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0944:Sgsm1
|
UTSW |
5 |
113,413,740 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1169:Sgsm1
|
UTSW |
5 |
113,427,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1232:Sgsm1
|
UTSW |
5 |
113,421,577 (GRCm39) |
nonsense |
probably null |
|
|
R1473:Sgsm1
|
UTSW |
5 |
113,411,123 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1535:Sgsm1
|
UTSW |
5 |
113,411,135 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1796:Sgsm1
|
UTSW |
5 |
113,421,483 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1878:Sgsm1
|
UTSW |
5 |
113,411,381 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2084:Sgsm1
|
UTSW |
5 |
113,433,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Sgsm1
|
UTSW |
5 |
113,411,125 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3856:Sgsm1
|
UTSW |
5 |
113,411,125 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4294:Sgsm1
|
UTSW |
5 |
113,433,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4373:Sgsm1
|
UTSW |
5 |
113,405,989 (GRCm39) |
intron |
probably benign |
|
|
R4558:Sgsm1
|
UTSW |
5 |
113,405,977 (GRCm39) |
intron |
probably benign |
|
|
R4610:Sgsm1
|
UTSW |
5 |
113,403,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4667:Sgsm1
|
UTSW |
5 |
113,407,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4890:Sgsm1
|
UTSW |
5 |
113,428,328 (GRCm39) |
intron |
probably benign |
|
|
R4992:Sgsm1
|
UTSW |
5 |
113,430,486 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5366:Sgsm1
|
UTSW |
5 |
113,398,905 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5776:Sgsm1
|
UTSW |
5 |
113,398,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Sgsm1
|
UTSW |
5 |
113,398,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6000:Sgsm1
|
UTSW |
5 |
113,434,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6354:Sgsm1
|
UTSW |
5 |
113,430,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6440:Sgsm1
|
UTSW |
5 |
113,426,997 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6831:Sgsm1
|
UTSW |
5 |
113,428,246 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7307:Sgsm1
|
UTSW |
5 |
113,421,512 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7309:Sgsm1
|
UTSW |
5 |
113,416,712 (GRCm39) |
splice site |
probably null |
|
|
R7387:Sgsm1
|
UTSW |
5 |
113,411,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7439:Sgsm1
|
UTSW |
5 |
113,422,187 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7485:Sgsm1
|
UTSW |
5 |
113,427,501 (GRCm39) |
splice site |
probably null |
|
|
R7624:Sgsm1
|
UTSW |
5 |
113,422,201 (GRCm39) |
nonsense |
probably null |
|
|
R7632:Sgsm1
|
UTSW |
5 |
113,423,948 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7669:Sgsm1
|
UTSW |
5 |
113,400,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7727:Sgsm1
|
UTSW |
5 |
113,422,193 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7732:Sgsm1
|
UTSW |
5 |
113,414,196 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7961:Sgsm1
|
UTSW |
5 |
113,430,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8088:Sgsm1
|
UTSW |
5 |
113,403,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8213:Sgsm1
|
UTSW |
5 |
113,398,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8278:Sgsm1
|
UTSW |
5 |
113,407,958 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8480:Sgsm1
|
UTSW |
5 |
113,411,284 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8796:Sgsm1
|
UTSW |
5 |
113,411,123 (GRCm39) |
missense |
probably benign |
0.15 |
|
R8816:Sgsm1
|
UTSW |
5 |
113,435,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8904:Sgsm1
|
UTSW |
5 |
113,421,495 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8905:Sgsm1
|
UTSW |
5 |
113,421,495 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8952:Sgsm1
|
UTSW |
5 |
113,432,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Sgsm1
|
UTSW |
5 |
113,436,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9162:Sgsm1
|
UTSW |
5 |
113,430,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9249:Sgsm1
|
UTSW |
5 |
113,428,201 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9375:Sgsm1
|
UTSW |
5 |
113,422,139 (GRCm39) |
missense |
unknown |
|
|
R9377:Sgsm1
|
UTSW |
5 |
113,436,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9461:Sgsm1
|
UTSW |
5 |
113,423,898 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9662:Sgsm1
|
UTSW |
5 |
113,427,097 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9722:Sgsm1
|
UTSW |
5 |
113,428,207 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R9726:Sgsm1
|
UTSW |
5 |
113,458,418 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Sgsm1
|
UTSW |
5 |
113,430,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGTGTTCCTTCTGAAGCTACAGC -3'
(R):5'- ACTGCAGGTGGTTTCTCTGC -3'
Sequencing Primer
(F):5'- CTACAGCAGCAGGGAGGC -3'
(R):5'- CTGCTCGCTGGGCTTATGC -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation