Incidental Mutation 'R4838:Kif13a'
| ID |
371565 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kif13a
|
| Ensembl Gene |
ENSMUSG00000021375 |
| Gene Name |
kinesin family member 13A |
| Synonyms |
4930505I07Rik, N-3 kinesin |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.268)
|
| Stock # |
R4838 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
46902563-47083343 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46980224 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Arginine
at position 176
(K176R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055304
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056978]
[ENSMUST00000225591]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000056978
AA Change: K176R
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000055304
Gene: ENSMUSG00000021375
AA Change: K176R
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
360 |
2.69e-175 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
low complexity region
|
391 |
406 |
N/A |
INTRINSIC |
|
FHA
|
469 |
519 |
7.16e-2 |
SMART |
|
coiled coil region
|
605 |
639 |
N/A |
INTRINSIC |
|
coiled coil region
|
664 |
704 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
748 |
792 |
1.7e-19 |
PFAM |
|
low complexity region
|
840 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
915 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1003 |
1270 |
2.2e-39 |
PFAM |
|
low complexity region
|
1401 |
1412 |
N/A |
INTRINSIC |
|
low complexity region
|
1475 |
1492 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000225591
AA Change: K113R
PolyPhen 2
Score 0.872 (Sensitivity: 0.83; Specificity: 0.93)
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
T |
C |
7: 119,944,523 (GRCm39) |
V386A |
probably benign |
Het |
| Adk |
G |
A |
14: 21,419,154 (GRCm39) |
A247T |
probably damaging |
Het |
| Ankrd27 |
T |
A |
7: 35,291,231 (GRCm39) |
L9Q |
possibly damaging |
Het |
| Atad2 |
A |
G |
15: 57,966,679 (GRCm39) |
L638P |
probably damaging |
Het |
| Atf7ip |
T |
A |
6: 136,573,489 (GRCm39) |
D1009E |
probably benign |
Het |
| Bend7 |
A |
T |
2: 4,749,133 (GRCm39) |
K83N |
probably damaging |
Het |
| Bicc1 |
C |
T |
10: 70,781,146 (GRCm39) |
D562N |
possibly damaging |
Het |
| Calcrl |
T |
A |
2: 84,181,549 (GRCm39) |
N200Y |
probably damaging |
Het |
| Ccdc125 |
C |
A |
13: 100,814,453 (GRCm39) |
A11E |
possibly damaging |
Het |
| Cd5l |
A |
G |
3: 87,273,258 (GRCm39) |
T76A |
probably benign |
Het |
| Cdhr5 |
A |
T |
7: 140,853,644 (GRCm39) |
I2N |
probably damaging |
Het |
| Cdk10 |
C |
T |
8: 123,957,353 (GRCm39) |
A230V |
probably damaging |
Het |
| Cep128 |
T |
C |
12: 90,966,319 (GRCm39) |
|
probably benign |
Het |
| Cep131 |
T |
C |
11: 119,966,982 (GRCm39) |
N186D |
probably damaging |
Het |
| Cfhr4 |
T |
A |
1: 139,661,181 (GRCm39) |
D556V |
probably damaging |
Het |
| Cog7 |
G |
T |
7: 121,570,604 (GRCm39) |
P168Q |
probably damaging |
Het |
| Col28a1 |
T |
A |
6: 8,014,559 (GRCm39) |
M949L |
probably benign |
Het |
| Coq8b |
T |
A |
7: 26,950,016 (GRCm39) |
M365K |
probably damaging |
Het |
| Cpa1 |
A |
G |
6: 30,639,515 (GRCm39) |
E18G |
possibly damaging |
Het |
| Csmd2 |
A |
G |
4: 128,411,542 (GRCm39) |
H2520R |
probably benign |
Het |
| Cyp2c69 |
T |
C |
19: 39,866,038 (GRCm39) |
N185S |
probably benign |
Het |
| Dpm1 |
G |
A |
2: 168,052,456 (GRCm39) |
T260I |
probably damaging |
Het |
| Dtx3 |
A |
T |
10: 127,027,176 (GRCm39) |
|
probably null |
Het |
| Eepd1 |
T |
C |
9: 25,500,756 (GRCm39) |
V401A |
possibly damaging |
Het |
| Ehhadh |
A |
G |
16: 21,581,952 (GRCm39) |
S347P |
possibly damaging |
Het |
| Elp3 |
A |
G |
14: 65,785,313 (GRCm39) |
|
probably null |
Het |
| Enam |
C |
T |
5: 88,640,967 (GRCm39) |
Q210* |
probably null |
Het |
| Epha1 |
C |
T |
6: 42,340,750 (GRCm39) |
R607H |
probably benign |
Het |
| Erich6 |
A |
G |
3: 58,544,251 (GRCm39) |
I112T |
probably benign |
Het |
| F830045P16Rik |
A |
G |
2: 129,302,470 (GRCm39) |
V374A |
possibly damaging |
Het |
| Fam171a2 |
C |
A |
11: 102,329,511 (GRCm39) |
R416L |
possibly damaging |
Het |
| Fbn1 |
T |
C |
2: 125,214,319 (GRCm39) |
N764S |
probably benign |
Het |
| Fip1l1 |
C |
T |
5: 74,752,600 (GRCm39) |
T469I |
probably damaging |
Het |
| Flad1 |
G |
A |
3: 89,313,217 (GRCm39) |
R342C |
probably damaging |
Het |
| Fzd3 |
A |
G |
14: 65,477,269 (GRCm39) |
V95A |
probably benign |
Het |
| Garem1 |
T |
C |
18: 21,280,950 (GRCm39) |
T469A |
probably benign |
Het |
| Gm17093 |
A |
G |
14: 44,755,805 (GRCm39) |
Y24C |
unknown |
Het |
| Grap2 |
T |
C |
15: 80,522,762 (GRCm39) |
V96A |
possibly damaging |
Het |
| Greb1 |
A |
T |
12: 16,734,361 (GRCm39) |
|
probably null |
Het |
| Grid2ip |
A |
T |
5: 143,374,530 (GRCm39) |
K913* |
probably null |
Het |
| Gzmk |
T |
C |
13: 113,309,555 (GRCm39) |
D126G |
probably damaging |
Het |
| Hibch |
A |
G |
1: 52,924,337 (GRCm39) |
I171V |
possibly damaging |
Het |
| Hipk2 |
G |
T |
6: 38,795,339 (GRCm39) |
T310K |
possibly damaging |
Het |
| Hk3 |
T |
C |
13: 55,154,231 (GRCm39) |
Y815C |
probably damaging |
Het |
| Hps5 |
A |
T |
7: 46,437,778 (GRCm39) |
V99E |
probably damaging |
Het |
| Hspg2 |
A |
G |
4: 137,268,977 (GRCm39) |
H2203R |
possibly damaging |
Het |
| Il12rb2 |
A |
G |
6: 67,286,121 (GRCm39) |
V108A |
probably damaging |
Het |
| Il6st |
C |
T |
13: 112,627,044 (GRCm39) |
R279* |
probably null |
Het |
| Kdm2a |
A |
C |
19: 4,375,054 (GRCm39) |
S692R |
probably benign |
Het |
| Kif5b |
T |
C |
18: 6,216,869 (GRCm39) |
K485E |
probably damaging |
Het |
| Ktn1 |
C |
T |
14: 47,963,413 (GRCm39) |
R1111* |
probably null |
Het |
| Lrrc23 |
A |
T |
6: 124,755,152 (GRCm39) |
N128K |
probably benign |
Het |
| Mad1l1 |
G |
A |
5: 140,286,017 (GRCm39) |
Q293* |
probably null |
Het |
| Man1b1 |
A |
T |
2: 25,235,487 (GRCm39) |
I338F |
possibly damaging |
Het |
| Marchf1 |
G |
T |
8: 66,921,015 (GRCm39) |
V225L |
probably damaging |
Het |
| Matcap2 |
A |
T |
9: 22,335,673 (GRCm39) |
D97V |
probably damaging |
Het |
| Mrpl3 |
A |
G |
9: 104,934,231 (GRCm39) |
D118G |
probably damaging |
Het |
| Nomo1 |
A |
T |
7: 45,733,139 (GRCm39) |
Q1209L |
unknown |
Het |
| Nrcam |
A |
G |
12: 44,620,802 (GRCm39) |
E949G |
probably damaging |
Het |
| Olfm5 |
T |
G |
7: 103,803,572 (GRCm39) |
N297T |
probably damaging |
Het |
| Or51h7 |
T |
A |
7: 102,591,453 (GRCm39) |
L110F |
probably damaging |
Het |
| Pcdh7 |
A |
T |
5: 57,878,146 (GRCm39) |
N567I |
probably damaging |
Het |
| Pkn1 |
A |
G |
8: 84,404,595 (GRCm39) |
L495P |
probably damaging |
Het |
| Pkp1 |
T |
C |
1: 135,810,326 (GRCm39) |
S415G |
probably damaging |
Het |
| Pou2f1 |
T |
A |
1: 165,744,492 (GRCm39) |
Q53L |
probably null |
Het |
| Pramel26 |
G |
A |
4: 143,537,375 (GRCm39) |
Q319* |
probably null |
Het |
| Prkce |
A |
G |
17: 86,937,511 (GRCm39) |
K648R |
probably benign |
Het |
| Ptprh |
G |
A |
7: 4,576,429 (GRCm39) |
T277I |
possibly damaging |
Het |
| Rpl31 |
C |
T |
1: 39,410,048 (GRCm39) |
R83C |
probably benign |
Het |
| Rpusd3 |
G |
A |
6: 113,393,837 (GRCm39) |
Q194* |
probably null |
Het |
| Sgsm1 |
T |
A |
5: 113,430,492 (GRCm39) |
N298Y |
probably damaging |
Het |
| She |
G |
A |
3: 89,758,946 (GRCm39) |
G355D |
probably benign |
Het |
| Shld2 |
A |
G |
14: 33,990,582 (GRCm39) |
V108A |
probably benign |
Het |
| Snx11 |
C |
T |
11: 96,665,284 (GRCm39) |
E9K |
possibly damaging |
Het |
| Soat1 |
C |
A |
1: 156,260,507 (GRCm39) |
A444S |
probably benign |
Het |
| Sox6 |
T |
C |
7: 115,085,897 (GRCm39) |
Y690C |
probably damaging |
Het |
| Spata13 |
T |
A |
14: 60,970,628 (GRCm39) |
F10I |
probably benign |
Het |
| St18 |
C |
A |
1: 6,873,129 (GRCm39) |
T288K |
probably benign |
Het |
| Tifa |
C |
T |
3: 127,590,235 (GRCm39) |
S2F |
probably damaging |
Het |
| Tmem232 |
A |
T |
17: 65,737,883 (GRCm39) |
S392R |
probably benign |
Het |
| Tmtc3 |
T |
C |
10: 100,302,082 (GRCm39) |
N289S |
probably damaging |
Het |
| Tpo |
A |
G |
12: 30,142,633 (GRCm39) |
F697S |
probably damaging |
Het |
| Trp53 |
A |
G |
11: 69,478,456 (GRCm39) |
T122A |
probably damaging |
Het |
| Trps1 |
A |
C |
15: 50,690,712 (GRCm39) |
I10S |
probably benign |
Het |
| Tubgcp5 |
C |
T |
7: 55,443,933 (GRCm39) |
|
probably benign |
Het |
| Unc13c |
T |
G |
9: 73,839,354 (GRCm39) |
Y499S |
possibly damaging |
Het |
| Unc45a |
C |
A |
7: 79,982,783 (GRCm39) |
D381Y |
probably damaging |
Het |
| Upf1 |
G |
C |
8: 70,792,018 (GRCm39) |
H402Q |
probably benign |
Het |
| Uroc1 |
A |
T |
6: 90,326,174 (GRCm39) |
I510F |
possibly damaging |
Het |
| Usp15 |
A |
G |
10: 122,963,662 (GRCm39) |
F589L |
probably damaging |
Het |
| Vmn2r76 |
T |
C |
7: 85,874,733 (GRCm39) |
Y748C |
probably damaging |
Het |
| Wwp1 |
T |
C |
4: 19,662,143 (GRCm39) |
N151D |
probably benign |
Het |
| Zbtb40 |
A |
T |
4: 136,728,527 (GRCm39) |
S439T |
probably benign |
Het |
| Zbtb6 |
A |
T |
2: 37,318,728 (GRCm39) |
L400* |
probably null |
Het |
| Zfp125 |
C |
T |
12: 20,949,961 (GRCm39) |
|
noncoding transcript |
Het |
| Zmynd8 |
A |
C |
2: 165,681,954 (GRCm39) |
Y183* |
probably null |
Het |
| Zpld2 |
A |
G |
4: 133,920,410 (GRCm39) |
V585A |
probably benign |
Het |
|
| Other mutations in Kif13a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01084:Kif13a
|
APN |
13 |
46,904,110 (GRCm39) |
splice site |
probably benign |
|
|
IGL01433:Kif13a
|
APN |
13 |
46,926,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01528:Kif13a
|
APN |
13 |
47,018,313 (GRCm39) |
splice site |
probably benign |
|
|
IGL01536:Kif13a
|
APN |
13 |
46,905,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01620:Kif13a
|
APN |
13 |
47,018,296 (GRCm39) |
missense |
probably benign |
|
|
IGL02020:Kif13a
|
APN |
13 |
46,947,495 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02142:Kif13a
|
APN |
13 |
46,925,011 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02375:Kif13a
|
APN |
13 |
46,978,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02407:Kif13a
|
APN |
13 |
46,938,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02476:Kif13a
|
APN |
13 |
46,938,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03038:Kif13a
|
APN |
13 |
46,926,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03053:Kif13a
|
APN |
13 |
46,905,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03366:Kif13a
|
APN |
13 |
46,918,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0025:Kif13a
|
UTSW |
13 |
46,939,987 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Kif13a
|
UTSW |
13 |
46,947,419 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0137:Kif13a
|
UTSW |
13 |
46,918,079 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0243:Kif13a
|
UTSW |
13 |
46,944,827 (GRCm39) |
missense |
probably benign |
0.24 |
|
R0346:Kif13a
|
UTSW |
13 |
46,967,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0403:Kif13a
|
UTSW |
13 |
46,944,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0492:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0607:Kif13a
|
UTSW |
13 |
46,956,187 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0631:Kif13a
|
UTSW |
13 |
46,932,364 (GRCm39) |
unclassified |
probably benign |
|
|
R0654:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0697:Kif13a
|
UTSW |
13 |
47,001,813 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0699:Kif13a
|
UTSW |
13 |
46,952,689 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0715:Kif13a
|
UTSW |
13 |
46,966,299 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Kif13a
|
UTSW |
13 |
46,967,712 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0903:Kif13a
|
UTSW |
13 |
47,082,735 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1419:Kif13a
|
UTSW |
13 |
46,978,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Kif13a
|
UTSW |
13 |
46,944,987 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Kif13a
|
UTSW |
13 |
46,966,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Kif13a
|
UTSW |
13 |
47,083,088 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1541:Kif13a
|
UTSW |
13 |
46,962,689 (GRCm39) |
missense |
probably benign |
|
|
R1579:Kif13a
|
UTSW |
13 |
46,906,332 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1582:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1752:Kif13a
|
UTSW |
13 |
46,951,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1755:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1755:Kif13a
|
UTSW |
13 |
46,906,089 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1858:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1891:Kif13a
|
UTSW |
13 |
47,082,695 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1902:Kif13a
|
UTSW |
13 |
46,941,638 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1928:Kif13a
|
UTSW |
13 |
46,966,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1961:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R2016:Kif13a
|
UTSW |
13 |
46,964,275 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2139:Kif13a
|
UTSW |
13 |
46,905,945 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Kif13a
|
UTSW |
13 |
46,922,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2407:Kif13a
|
UTSW |
13 |
46,930,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Kif13a
|
UTSW |
13 |
46,967,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3122:Kif13a
|
UTSW |
13 |
46,918,072 (GRCm39) |
splice site |
probably benign |
|
|
R3499:Kif13a
|
UTSW |
13 |
46,978,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3905:Kif13a
|
UTSW |
13 |
46,956,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Kif13a
|
UTSW |
13 |
46,967,631 (GRCm39) |
splice site |
probably null |
|
|
R4771:Kif13a
|
UTSW |
13 |
46,978,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Kif13a
|
UTSW |
13 |
47,083,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4931:Kif13a
|
UTSW |
13 |
46,962,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4980:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4992:Kif13a
|
UTSW |
13 |
46,930,639 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5047:Kif13a
|
UTSW |
13 |
46,941,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5054:Kif13a
|
UTSW |
13 |
46,956,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5141:Kif13a
|
UTSW |
13 |
46,906,197 (GRCm39) |
missense |
probably benign |
|
|
R5329:Kif13a
|
UTSW |
13 |
46,928,877 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5429:Kif13a
|
UTSW |
13 |
46,926,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5499:Kif13a
|
UTSW |
13 |
46,986,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Kif13a
|
UTSW |
13 |
46,905,591 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5594:Kif13a
|
UTSW |
13 |
46,906,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Kif13a
|
UTSW |
13 |
46,978,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5964:Kif13a
|
UTSW |
13 |
46,925,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6115:Kif13a
|
UTSW |
13 |
46,954,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6317:Kif13a
|
UTSW |
13 |
46,980,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Kif13a
|
UTSW |
13 |
46,968,683 (GRCm39) |
splice site |
probably null |
|
|
R6393:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6394:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6395:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6735:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7037:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7038:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7039:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7237:Kif13a
|
UTSW |
13 |
46,962,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7285:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7286:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7287:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7341:Kif13a
|
UTSW |
13 |
46,980,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7693:Kif13a
|
UTSW |
13 |
46,904,089 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7761:Kif13a
|
UTSW |
13 |
46,951,955 (GRCm39) |
missense |
probably benign |
|
|
R8098:Kif13a
|
UTSW |
13 |
46,968,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Kif13a
|
UTSW |
13 |
46,932,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Kif13a
|
UTSW |
13 |
46,906,057 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8806:Kif13a
|
UTSW |
13 |
46,914,813 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8871:Kif13a
|
UTSW |
13 |
46,984,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8877:Kif13a
|
UTSW |
13 |
46,954,921 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8906:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9028:Kif13a
|
UTSW |
13 |
46,951,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kif13a
|
UTSW |
13 |
46,944,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9062:Kif13a
|
UTSW |
13 |
46,941,536 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9070:Kif13a
|
UTSW |
13 |
46,905,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9083:Kif13a
|
UTSW |
13 |
46,966,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9250:Kif13a
|
UTSW |
13 |
46,928,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Kif13a
|
UTSW |
13 |
46,951,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9360:Kif13a
|
UTSW |
13 |
46,962,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9369:Kif13a
|
UTSW |
13 |
46,940,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9589:Kif13a
|
UTSW |
13 |
46,956,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9749:Kif13a
|
UTSW |
13 |
46,914,227 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0013:Kif13a
|
UTSW |
13 |
47,082,746 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACAAGGCAGCCTGAAGTGTG -3'
(R):5'- ATAAAGTGGCCATTAAAGCACCTTC -3'
Sequencing Primer
(F):5'- GTGTGACTGAAGGACACCATTCC -3'
(R):5'- GTGGCCATTAAAGCACCTTCTAATC -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation